ILamivudine neZidovudine

-Delile

• Ngaphambi kokuthatha i-lamivudine ne-zidovudine,
• ILamivudine ne-zidovudine kungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Imiphumela emibi elandelayo ayivamile, kepha uma uhlangabezana nayo, noma enye yalezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

ILamivudine ne-zidovudine kungehlisa inani lamaseli athile egazini lakho, kufaka phakathi amaseli egazi abomvu namhlophe. Tshela udokotela wakho uma ngabe uke waba nenombolo ephansi yanoma yiluphi uhlobo lwamangqamuzana egazi noma noma yikuphi ukuphazamiseka kwegazi okufana ne-anemia (inani eliphansi kunejwayelekile lamaseli abomvu egazi) noma izinkinga zomnkantsha. Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: ukopha okungavamile noma ukulimaza; ukuphelelwa umoya; isikhumba esiphaphathekile; umkhuhlane, umphimbo obuhlungu, amakhaza nezinye izimpawu zokutheleleka; ukukhathala okungajwayelekile noma ubuthakathaka.

ILamivudine ne-zidovudine kungadala ukuphazamiseka kwemisipha, ikakhulukazi uma kusetshenziswa isikhathi eside. Tshela udokotela wakho uma ngabe uke waba nesifo semisipha noma semisipha ebuthakathaka. Uma uzwa ubuhlungu bemisipha noma ubuthakathaka bemisipha, shayela udokotela wakho ngokushesha.

ILamivudine ne-zidovudine kungadala umonakalo osongela impilo esibindini kanye nesimo esingaba yingozi esibizwa nge-lactic acidosis (i-lactic acid egazini). Tshela udokotela wakho uma uke waba nesifo sesibindi noma wake waba naso. Uma unesifo sesibindi udokotela wakho mhlawumbe uzokutshela ukuthi ungathathi i-lamivudine ne-zidovudine. Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo: isicanucanu, ukuhlanza, ubuhlungu engxenyeni engakwesokudla esiswini sakho, ukulahlekelwa isifiso sokudla, ukukhathala ngokweqile, ukopha okungavamile noma ukulimaza, ubuthakathaka, isiyezi, ikhanda elikhanyayo , ukushaya kwenhliziyo okusheshayo noma okungajwayelekile, ukuphefumula kanzima, umchamo omnyama ophuzi noma onsundu, ukunyakaza kwamathumbu anombala okhanyayo, ukuphuzi kwesikhumba noma kwamehlo, ukuzwa ukubanda, ikakhulukazi ezingalweni noma emilenzeni, noma ubuhlungu bemisipha obuhlukile kunanoma yibuphi ubuhlungu bemisipha ojwayele ukubenza isipiliyoni.

Tshela udokotela wakho uma une noma ucabanga ukuthi ungaba nokutheleleka ngegciwane le-hepatitis B (HBV; ukutheleleka kwesibindi okuqhubekayo). Udokotela wakho angakuhlola ukuthi unayo yini i-HBV ngaphambi kokuba uqale ukwelashwa kwakho nge-lamivudine ne-zidovudine. Uma une-HBV futhi uphuza i-lamivudine ne-zidovudine, isimo sakho singase sibe sibi ngokungazelelwe lapho uyeka ukuthatha i-lamivudine ne-zidovudine. Udokotela wakho uzokuhlola futhi a-oda izivivinyo zebhu njalo ezinyangeni ezimbalwa ngemuva kokuyeka ukuthatha i-lamivudine ukubona ukuthi i-HBV yakho isiba kubi kakhulu.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ngesikhathi nangemva kokwelashwa kwakho ukuze ahlole impendulo yomzimba wakho ku-lamivudine ne-zidovudine.

Inhlanganisela ye-lamivudine ne-zidovudine isetshenziswa kanye neminye imithi yokwelapha ukutheleleka ngegciwane lesandulela ngculaza (i-HIV). ILamivudine ne-zidovudine basesigabeni semithi ebizwa nge-nucleoside reverse transcriptase inhibitors (NRTIs). Basebenza ngokunciphisa inani le-HIV egazini. Yize inhlanganisela ye-lamivudine ne-zidovudine ingayelaphi i-HIV, ingahle inciphise amathuba akho okuba ne-immunodeficiency syndrome (i-AIDS) kanye nezifo ezihlobene ne-HIV ezifana nokutheleleka okunzima noma umdlavuza. Ukuthatha le mithi kanye nokwenza ucansi oluphephile nokwenza ezinye izinguquko endleleni yokuphila kunganciphisa ubungozi bokudlulisela (ukusabalalisa) igciwane le-HIV kwabanye abantu.

Inhlanganisela ye-lamivudine ne-zidovudine iza njengethebhulethi ezothathwa ngomlomo. Imvamisa kuthathwa kabili ngosuku noma ngaphandle kokudla. Thatha i-lamivudine ne-zidovudine ngezikhathi ezifanayo nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha le mithi ngendlela eqondiswe ngayo. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

ILamivudine ne-zidovudine ilawula ukutheleleka nge-HIV kepha ayiyelaphi. Qhubeka uphuze i-lamivudine ne-zidovudine noma ngabe uzizwa uphilile.Ungayeki ukuthatha i-lamivudine ne-zidovudine ngaphandle kokukhuluma nodokotela wakho. Lapho ukunikezwa kwakho kwe-lamivudine ne-zidovudine kuqala ukwehla, thola okuningi kudokotela wakho noma ekhemisi. Uma uphuthelwa imithamo noma uyeka ukuthatha i-lamivudine ne-zidovudine, isimo sakho singase sibe nzima ukwelashwa.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-lamivudine ne-zidovudine,

• Tshela udokotela wakho noma usokhemisi uma unegciwane ku-lamivudine (i-Epivir, i-Epivir HBV, nabanye); i-zidovudine (i-Retrovir); noma imiphi eminye imithi; noma yiziphi izithako kumaphilisi e-lamivudine ne-zidovudine. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela nemishanguzo ongayinikiwe, amavithamini, izithasiselo zokudla okunempilo nemikhiqizo yamakhambi oyithathayo. Qiniseka ukuthi usho noma yikuphi okulandelayo: i-atovaquone (Malarone, Mepron), imithi ethile yomdlavuza efana ne-doxorubicin (Doxil), i-fluconazole (i-Diflucan), i-ganciclovir (i-Cytovene, i-Valcyte), i-interferon alpha, i-methadone (i-Dolophine, i-Methadose), i-ribavirin (i-Copegus, i-Rebetrol, abanye), i-rifampin (i-Rifadin, i-Rimactane, i-Rifamate, i-Rifater), ne-stavudine (i-Zerit). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imithi eminingi ingaxhumana ne-lamivudine ne-zidovudine, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu.
• ngaphezu kwezimo ezibalwe esigabeni SESEXWAYISO ESIBALULEKILE, tshela udokotela wakho uma uke waba ne-pancreatitis noma (wake wavuvukala amanyikwe angapheli) noma isifo sezinso.
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha i-lamivudine ne-zidovudine, shayela udokotela wakho. Akufanele uncelise ibele uma utheleleke nge-HIV noma uma uphuza i-lamivudine ne-zidovudine.
• kufanele wazi ukuthi amafutha omzimba wakho angakhuphuka noma ahambele ezindaweni ezahlukahlukene zomzimba wakho, njengasemhlane wakho ongaphezulu, entanyeni (’’ inyathi ’), amabele, nasesizungeze isisu sakho. Ungaqaphela ukulahleka kwamafutha omzimba ebusweni bakho, emilenzeni nasezingalweni.
• kufanele wazi ukuthi ngenkathi uthatha imishanguzo yokwelapha ukutheleleka nge-HIV, amasosha omzimba wakho angaqina futhi aqale ukulwa nezinye izifo ezazivele zisemzimbeni wakho. Lokhu kungadala ukuthi ube nezimpawu zalezo zifo. Uma unezimpawu ezintsha noma eziya ziba zimbi noma kunini ngesikhathi sokwelashwa kwakho nge-lamivudine ne-zidovudine, qiniseka ukuthi utshela udokotela wakho.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

ILamivudine ne-zidovudine kungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ikhanda
• isifo sohudo
• isilungulela
• ubunzima bokulala noma ukulala
• ukudana
• ikhala eligcwele
• ukukhwehlela
• ubuhlungu obuhlangene

Eminye imiphumela emibi ingaba mibi. Imiphumela emibi elandelayo ayivamile, kepha uma uhlangabezana nayo, noma enye yalezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:

• isifuba
• ukuqubuka
• ukulunywa
• ukuphefumula kanzima noma ukugwinya
• ukuba ndikindiki, ukushosholoza, noma ukushisa eminweni noma ezinzwaneni
• imfiva
• isifuba

ILamivudine ne-zidovudine kungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha i-lamivudine ne-zidovudine.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina amaphilisi esiqandisini noma ekamelweni lokushisa kepha kude nokushisa nomswakama okweqile (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• ikhanda
• ukuhlanza
• ukukhathala ngokweqile

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Gcina i-lamivudine ne-zidovudine ezandleni zakho. Ungalindi uze uphelelwe yimithi yokugcwalisa imishanguzo yakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Inhlanganisela^®

• 3TC ne-ZDV
• 3TC ne-AZT
• I-3TC ne-azidothymidine