Isivivinyo sokucindezela i-hormone yokukhula

Isivivinyo sokucindezela i-hormone yokukhula sinquma ukuthi ngabe ukukhiqizwa kwe-hormone yokukhula (GH) kucindezelwa ushukela wegazi ophakeme.

Okungenani kuthathwa amasampuli egazi amathathu.

Ukuhlolwa kwenziwa ngale ndlela elandelayo:

• Isampula yokuqala yegazi iqoqwa phakathi kuka-6 ekuseni no-8 ekuseni ngaphambi kokuba udle noma uphuze noma yini.
• Ube usuphuza isisombululo esine-glucose (ushukela). Ungatshelwa ukuthi uphuze kancane ukugwema ukuba nesicanucanu. Kepha kufanele uphuze isixazululo kungakapheli imizuzu emihlanu ukuqinisekisa ukuthi imiphumela yokuhlolwa inembile.
• Amasampula egazi alandelayo ngokuvamile aqoqwa ihora eli-1 kuya kwele-2 ngemuva kokuqeda ukuphuza isisombululo se-glucose. Kwesinye isikhathi zithathwa njalo ngemizuzu engama-30 noma engama-60.
• Isampula ngayinye ithunyelwa elabhorethri khona manjalo. Ilebhu ilinganisa amazinga e-glucose ne-GH kusampula ngayinye.

Ungadli noma yini futhi ubeke umkhawulo ekusebenzeni komzimba amahora ayi-10 kuya kwayi-12 ngaphambi kokuhlolwa.

Ungatshelwa nokuthi uyeke ukuthatha imishanguzo engathinta imiphumela yokuhlolwa. Le mithi ifaka phakathi i-glucocorticoids efana ne-prednisone, hydrocortisone, noma i-dexamethasone. Buza kumhlinzeki wakho wezempilo ngaphambi kokumisa noma imiphi imithi.

Uzocelwa ukuthi uphumule okungenani imizuzu engama-90 ngaphambi kokuhlolwa. Lokhu kungenxa yokuthi ukuvivinya umzimba noma umsebenzi owandisiwe ungashintsha amazinga e-GH.

Uma ingane yakho izokwenza lokhu kuhlolwa, kungasiza ukuchaza ukuthi isivivinyo sizozizwa kanjani futhi sikhombise nodoli. Lapho ingane yakho ijwayelene ngokwengeziwe nokuthi kuzokwenzekani nokuthi kungani, ukukhathazeka okuncane ingane ezozwa ngakho.

Lapho inaliti ifakwa ukudonsa igazi, abanye abantu bezwa ubuhlungu obulinganiselayo. Abanye bazizwa beshaywa noma betinyelwa kuphela. Ngemuva kwalokho, kungahle kube nokushaywa okuthile noma ukulinyazeka okuncane. Lokhu maduzane kuyaphela.

Lokhu kuhlolwa kubheka izinga eliphakeme le-GH, isimo esiholela ekuphakameni kwezingane nase-acromegaly kubantu abadala. Ayisetshenziswa njengesivivinyo sokuhlola esijwayelekile. Lokhu kuhlolwa kwenziwa kuphela uma ukhombisa izimpawu zokwanda kwe-GH.

Imiphumela yokuhlola ejwayelekile ikhombisa ileveli ye-GH engaphansi kuka-1 ng / mL. Ezinganeni, izinga le-GH lingakhuphuka ngenxa ye-hypoglycemia esebenzayo.

Ububanzi bamanani ajwayelekile bungahluka kancane phakathi kwamalabhorethri ahlukene. Amanye amalebhu asebenzisa izilinganiso ezahlukahlukene noma avivinye amasampula ahlukile. Khuluma nomhlinzeki wakho mayelana nencazelo yemiphumela yakho ethile yokuhlolwa.

Uma izinga le-GH lingashintshiwe futhi lihlala liphezulu ngesikhathi sokuhlolwa kokucindezela, umhlinzeki uzosola i-gigantism noma i-acromegaly. Ungahle udinge ukuphinda ubuyekezwe ukuze uqinisekise imiphumela yokuhlolwa.

Kunengozi encane ethintekayo ekuthatheni igazi lakho. Imithambo nemithambo yegazi kuyahluka ngosayizi komunye umuntu kuya kolunye uhlangothi lomzimba kuya kolunye. Ukuthatha igazi kwabanye abantu kungaba nzima kakhulu ukwedlula kwabanye.

Izingozi zokudonswa igazi zincane, kepha zingafaka:

• Ukopha ngokweqile
• Ukubhoboza okuningi ukuthola imithambo
• Ukuquleka noma uzizwe unekhanda elincane
• Igazi elinqwabelana ngaphansi kwesikhumba (hematoma)
• Ukutheleleka (ingozi encane noma kunini lapho isikhumba siphukile)

Ukuhlolwa kokucindezelwa kwe-GH; Ukuhlolwa kokulayisha kwe-glucose; I-Acromegaly - ukuhlolwa kwegazi; I-Gigantism - ukuhlolwa kwegazi

• Ukuhlolwa kwegazi

UKaiser U, Ho K. Pituitary physiology kanye nokuhlolwa kokuxilongwa. Ku: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, abahleli. Incwadi kaWilliams ye-Endocrinology. Umhlaka 14. IPhiladelphia, PA: Elsevier; 2020: isahluko 8.

Ukuhlolwa kukaNakamoto J. Endocrine. Ku: Jameson JL, De Groot LJ, de Kretser DM, et al, abahleli. I-Endocrinology: Eyabantu Abadala Neyengane. Umhla wesi-7. IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 154.