Ukuhlolwa komchamo we-17-Ketosteroids

Ama-17-ketosteroids yizinto ezakhiwa lapho umzimba wehla ama-hormone wesilisa angama-steroid abizwa ngama-androgens namanye ama-hormone akhishwa yizinhlayiya ze-adrenal kwabesilisa nabesifazane, nangama-testes kwabesilisa.

Kudingeka isampula yamahora angama-24. Uzodinga ukuqoqa umchamo wakho ngaphezu kwamahora angama-24. Umhlinzeki wakho wezempilo uzokutshela ukuthi ungakwenza kanjani lokhu. Landela imiyalo ngqo ukuqinisekisa imiphumela enembile.

Umhlinzeki wakho uzokucela ukuthi umise okwesikhashana noma yimiphi imithi engathinta imiphumela yokuhlolwa. Qiniseka ukuthi utshela umhlinzeki wakho ngayo yonke imithi oyiphuzayo. Lokhu kufaka phakathi:

• Imithi elwa namagciwane
• I-aspirin (uma uku-aspirin yesikhathi eside)
• Amaphilisi okuvimbela inzalo
• I-diuretics (amaphilisi wamanzi)
• I-Estrogen

Ungayeki ukuthatha noma imuphi umuthi ngaphambi kokukhuluma nomhlinzeki wakho.

Ukuhlolwa kuhilela ukuchama okuvamile. Akukho ukungakhululeki.

Umhlinzeki wakho anga-oda lokhu kuhlolwa uma unezimpawu zokuphazamiseka okuhambisana namazinga angajwayelekile ama-androgens.

Amanani ajwayelekile angokulandelayo:

• Owesilisa: 7 kuya ku-20 mg ngamahora angama-24
• Owesifazane: 5 kuya ku-15 mg ngamahora angama-24

Ububanzi bamanani ajwayelekile bungahluka kancane phakathi kwamalabhorethri ahlukene. Amanye amalebhu asebenzisa izilinganiso ezahlukahlukene noma avivinye amasampula ahlukile. Khuluma nodokotela wakho mayelana nencazelo yemiphumela yakho ethile yokuhlolwa.

Amazinga akhuphukile we-17-ketosteroids angabangelwa:

• Izinkinga zezindlala ze-Adrenal ezifana nesimila, i-Cushing syndrome
• Ukungalingani kwamahomoni ezocansi kwabesifazane (i-polycystic ovary syndrome)
• Umdlavuza we-Ovarian
• Umdlavuza wamasende
• Indlala yegilo eyeqile
• Ukukhuluphala ngokweqile
• Ukucindezeleka

Ukwehla kwamazinga we-17-ketosteroids kungenzeka ngenxa:

• Izindlala ze-Adrenal azenzi ngokwanele ngamahomoni azo (Isifo i-Addison)
• Ukulimala kwezinso
• Indlala yamapayipi ayenzi ngokwanele amahomoni ayo (i-hypopituitarism)
• Ukususwa kwamasende (ukuthenwa)

Azikho izingozi ngalokhu kuhlolwa.

• Isampula yomchamo

UBertholf RL, uCooper M, uBusika WE. I-adrenal cortex. Ku: Rifai N, ed. I-Tietz Textbook ye-Clinical Chemistry kanye ne-Molecular Diagnostics. Umhlaka 6. ISt Louis, MO: Elsevier; 2018: isahluko 66.

Ukuhlolwa kukaNakamoto J. Endocrine. Ku: Jameson JL, De Groot LJ, de Kretser DM, et al, abahleli. I-Endocrinology: Eyabantu Abadala Neyengane. Umhla wesi-7. IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 154.