Ukuhlolwa kwe-Lactate dehydrogenase

I-Lactate dehydrogenase (LDH) yiprotheni esiza ukukhiqiza amandla emzimbeni. Ukuhlolwa kwe-LDH kukala inani le-LDH egazini.

Kudingeka isampula yegazi.

Akukho ukulungiselela okuthile okudingekayo.

Lapho inaliti ifakwa ukudonsa igazi, abanye abantu bezwa ubuhlungu obulinganiselayo. Abanye bazizwa beshaywa noma betinyelwa kuphela. Ngemuva kwalokho, kungahle kube nokushaywa okuthile noma ukulimazeka okuncane. Lokhu maduzane kuyaphela.

I-LDH ivame ukukalwa ukubheka ukulimala kwezicubu. I-LDH inezicubu zomzimba eziningi, ikakhulukazi inhliziyo, isibindi, izinso, imisipha, ubuchopho, amangqamuzana egazi namaphaphu.

Ezinye izimo okungenziwa ukuhlolwa kuzo zifaka:

• Isibalo samaseli abomvu aphansi (i-anemia)
• Umdlavuza, kufaka phakathi umdlavuza wegazi (i-leukemia) noma umdlavuza we-lymph (lymphoma)

Ibanga lenani elijwayelekile liyi-105 kuya kuma-333 amayunithi omhlaba ngelitha ngalinye (IU / L).

Ububanzi bamanani ajwayelekile bungahluka kancane phakathi kwamalabhorethri ahlukene. Amanye amalebhu asebenzisa izilinganiso ezahlukahlukene noma avivinye amasampula ahlukile. Khuluma nomhlinzeki wakho mayelana nencazelo yemiphumela yakho ethile.

Izinga eliphakeme kunokujwayelekile lingaveza:

• Ukuntuleka kokugeleza kwegazi (ischemia)
• Isifo senhliziyo
• I-hemolytic anemia
• I-mononucleosis ethathelwanayo
• I-leukemia noma i-lymphoma
• Isifo sesibindi (isibonelo, i-hepatitis)
• Umfutho wegazi ophansi
• Ukulimala kwemisipha
• Ubuthakathaka bemisipha nokulahleka kwezicubu zemisipha (muscular dystrophy)
• Ukwakhiwa okusha kwezicubu okungavamile (imvamisa umdlavuza)
• I-Pancreatitis
• Unhlangothi
• Ukufa kwezicubu

Uma ileveli yakho ye-LDH iphezulu, umhlinzeki wakho angancoma ukuhlolwa kwe-isoenzymes ye-LDH ukuthola indawo yokulimala kwezicubu.

Kunengozi encane ethintekayo ekuthatheni igazi lakho. Imithambo nemithambo yegazi kuyahluka ngosayizi komunye umuntu kuya kolunye uhlangothi lomzimba kuya kolunye. Ukuthatha igazi kwabanye abantu kungaba nzima kakhulu ukwedlula kwabanye.

Ezinye izingozi ezihambisana nokudonswa igazi zincane, kepha zingafaka:

• Ukopha ngokweqile
• Ukuquleka noma uzizwe unekhanda elincane
• Ukubhoboza okuningi ukuthola imithambo
• I-hematoma (i-blood buildup ngaphansi kwesikhumba)
• Ukutheleleka (ingozi encane noma kunini lapho isikhumba siphukile)

Ukuhlolwa kwe-LDH; Ukuhlolwa kwe-Lactic acid dehydrogenase

ICarty RP, iPincus MR, iSarafraz-Yazdi E.I-enzymology yomtholampilo. Ku: McPherson RA, Pincus MR, abahleli. UHenry’s Clinical Diagnosis and Management by Laboratory Methods. Umhla ka-23. ISt Louis, MO: Elsevier; I-2017: isahluko 20.

IChernecky CC, iBerger BJ. I-Lactate dehydrogenase. Ku: IChernecky CC, iBerger BJ, ama-eds. Ukuhlolwa Kwelabhoratri Nezinqubo Zokuxilonga. Umhlaka 6. ISt Louis, MO: Elsevier Saunders; 2013: 701-702.