Ukuhlolwa kwegazi kwe-Aspartate aminotransferase (AST)

Ukuhlolwa kwegazi kwe-aspartate aminotransferase (AST) kukala izinga le-enzyme AST egazini.

Kudingeka isampula yegazi.

Akukho ukulungiselela okukhethekile okudingekayo.

Lapho inaliti ifakwa ukudonsa igazi, abanye abantu bezwa ubuhlungu obulinganiselayo. Abanye bazizwa beshaywa noma betinyelwa kuphela. Ngemuva kwalokho, kungahle kube nokushaywa okuthile noma ukulimazeka okuncane. Lokhu maduzane kuyaphela.

I-AST iyi-enzyme etholakala emazingeni aphezulu esibindini, enhliziyweni nasemisipha. Kutholakala nangamanani amancane kwezinye izicubu. I-enzyme yiprotheni edala ushintsho oluthile lwamakhemikhali emzimbeni.

Ukulimala kwesibindi kubangela ukukhishwa kwe-AST egazini.

Lokhu kuhlolwa kwenziwa ikakhulukazi nezinye izivivinyo (njenge-ALT, ALP, ne-bilirubin) ukuthola nokuqapha izifo zesibindi.

Ububanzi obujwayelekile bungu-8 kuya ku-33 U / L.

Ububanzi bamanani ajwayelekile bungahluka kancane phakathi kwamalabhorethri ahlukene. Amanye amalebhu asebenzisa izilinganiso ezahlukahlukene noma angahlola amasampula ahlukile. Khuluma nomhlinzeki wakho wezokunakekelwa kwempilo mayelana nencazelo yemiphumela yakho ethile yokuhlolwa.

Izinga le-AST elandisiwe ngokuvamile liwuphawu lwesifo sesibindi. Isifo sesibindi sinamathuba amaningi kakhulu lapho amazinga ezinto ezihlolwe ngezinye izivivinyo zegazi lesibindi nawo enyukile.

Izinga le-AST elandisiwe lingahle lidalwe yilokhu okulandelayo:

• Ukuqubuka kwesibindi (i-cirrhosis)
• Ukufa kwezicubu zesibindi
• Isifo senhliziyo
• Insimbi eningi kakhulu emzimbeni (hemochromatosis)
• Isibindi sokuvuvukala esivuthayo (hepatitis)
• Ukuntuleka kokugeleza kwegazi kuye esibindini (isibindi ischemia)
• Umdlavuza wesibindi noma isimila
• Ukusetshenziswa kwezidakamizwa ezinobuthi esibindini, ikakhulukazi ukusetshenziswa kotshwala
• I-Mononucleosis ("mono")
• Isifo semisipha noma ukuhlukumezeka
• Amapancreas avuvukile futhi avuvukile (pancreatitis)

Izinga le-AST nalo lingakhuphuka ngemuva:

• Ukushisa (okujulile)
• Izinqubo zenhliziyo
• Ukudlikiza
• Ukuhlinzwa

Ukukhulelwa nokuvivinya umzimba nakho kungadala ukwanda kwe-AST.

Kunengozi encane ethintekayo ekuthatheni igazi lakho. Imithambo iyehluka ngobukhulu kusuka komunye umuntu iye komunye futhi kusukela kolunye uhlangothi lomzimba kuye kolunye. Ukuthatha igazi kwabanye abantu kungaba nzima kakhulu ukwedlula kwabanye.

Izingozi ezihambisana nokudonswa igazi zincane, kepha zingafaka:

• Ukuquleka noma uzizwe unekhanda elincane
• Ukopha ngokweqile
• Ukubhoboza okuningi ukuthola imithambo
• I-Hematoma (ukuqoqa igazi ngaphansi kwesikhumba)
• Ukutheleleka (ingozi encane noma kunini lapho isikhumba siphukile)

I-aspartate aminotransferase; I-serum glutamic-oxaloacetic transaminase; SGOT

IChernecky CC, iBerger BJ. I-Aspartate aminotransferase (AST, aspartate transaminase, SGOT) - i-serum. Ku: IChernecky CC, iBerger BJ, ama-eds. Ukuhlolwa Kwelabhoratri Nezinqubo Zokuxilonga. Umhlaka 6. ISt Louis, MO: Elsevier Saunders; 2013: 172-173.

UPincus MR, u-Tierno PM, uGleeson E, uBowne WB, uBluth MH. Ukuhlolwa kokusebenza kwesibindi. Ku: McPherson RA, Pincus MR, abahleli. UHenry’s Clinical Diagnosis and Management by Laboratory Methods. Umhla ka-23. ISt Louis, MO: Elsevier; I-2017: isahluko 21.

IPratt DS. I-chemistry yesibindi nokuhlolwa kokusebenza. Ku: Feldman M, Friedman LS, Brandt LJ, ama-eds. Sleisenger kanye neFordtran's Gastrointestinal and Liver Disease. Umhlaka 10. IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 73.