Uric acid - igazi

I-Uric acid ikhemikhali elenziwa lapho umzimba wephula izinto ezibizwa ngama-purines. Ama-purines ngokuvamile akhiqizwa emzimbeni futhi atholakala kokunye ukudla neziphuzo. Ukudla okunokuqukethwe okuphezulu kwama-purine kufaka phakathi isibindi, ama-anchovies, ama-mackerel, ubhontshisi omisiwe nophizi, nobhiya.

Iningi le-uric acid lincibilika egazini bese liya ezinso. Ukusuka lapho, iphuma ichame. Uma umzimba wakho ukhiqiza i-uric acid eningi kakhulu noma ungayikhiphi ngokwanele, ungagula. Izinga eliphezulu le-uric acid egazini libizwa nge-hyperuricemia.

Lokhu kuhlolwa kubheka ukuthi ungakanani uric acid onayo egazini lakho. Olunye uvivinyo lungasetshenziswa ukuhlola izinga le-uric acid emchameni wakho.

Kudingeka isampula yegazi. Isikhathi esiningi, igazi likhishwa emthanjeni ongaphakathi endololwaneni noma ngemuva kwesandla.

Akufanele udle noma uphuze noma yini amahora amane ngaphambi kokuhlolwa ngaphandle kokuthi utshelwe ngenye indlela.

Imithi eminingi ingaphazamisa imiphumela yokuhlolwa kwegazi.

• Umhlinzeki wakho wezokunakekelwa kwempilo uzokutshela uma kudingeka uyeke ukuthatha noma yimiphi imithi ngaphambi kokwenza lokhu kuhlolwa.
• UNGAYIMISI noma ushintshe imithi yakho ngaphandle kokukhuluma nomhlinzeki wakho kuqala.

Lokhu kuhlolwa kwenziwa ukubona ukuthi unezinga eliphezulu le-uric acid egazini lakho. Izinga eliphakeme le-uric acid kwesinye isikhathi lingadala ukuthi igout noma isifo sezinso.

Ungaba nalolu vivinyo uma ngabe unazo noma usuzoba nezinhlobo ezithile ze-chemotherapy. Ukubhujiswa okusheshayo kwamaseli anomdlavuza noma ukwehla kwesisindo, okungenzeka ngezindlela ezinjalo zokwelapha, kungakhuphula inani le-uric acid egazini lakho.

Amanani ajwayelekile aphakathi kwamamiligram ayi-3.5 kuye kwayi-7.2 nge-deciliter ngayinye (mg / dL).

Ububanzi bamanani ajwayelekile bungahluka kancane phakathi kwamalabhorethri ahlukene. Khuluma nomhlinzeki wakho mayelana nencazelo yemiphumela yakho ethile yokuhlolwa.

Isibonelo esingenhla sikhombisa ibanga lesilinganiso elijwayelekile lemiphumela yalezi zivivinyo. Amanye ama-laboratories asebenzisa izilinganiso ezahlukahlukene noma angahlola izinhlobo ezahlukene.

Amazinga amakhulu kune-evamile e-uric acid (hyperuricemia) angabangelwa:

• I-Acidosis
• Ukuphuza ngokweqile
• Imiphumela emibi ehlobene ne-Chemotherapy
• Ukwehla emzimbeni, imvamisa kungenxa yemithi ekhishwa isisu
• Isifo sikashukela
• Ukuvivinya umzimba ngokweqile
• I-Hypoparathyroidism
• Ubuthi bomthofu
• Umdlavuza wegazi
• Isifo sezinso seMedullary cystic
• I-Polycythemia vera
• Ukudla okunothe nge-purine
• Ukwehluleka kwezinso
• I-toxemia yokukhulelwa

Amaleveli we-uric acid angaphansi kokujwayelekile angahle abe ngenxa ye:

• I-Fanconi syndrome
• Izifo ezibangelwa ifa le-metabolism
• Ukutheleleka nge-HIV
• Isifo sesibindi
• Ukudla okuphansi kwe-purine
• Imithi efana ne-fenofibrate, losartan, ne-trimethoprim-sulfmethoxazole
• I-Syndrome yemfihlo ye-antidiuretic hormone (SIADH) engafanele

Ezinye izizathu okungenzeka ukuthi kwenziwe lolu vivinyo zifaka:

• Isifo sezinso esingalapheki
• Gout
• Ukulimala kwezinso ne-ureter
• Amatshe ezinso (nephrolithiasis)

I-Gout - i-uric acid egazini; Hyperuricemia - uric acid egazini

• Ukuhlolwa kwegazi
• Amakhemikhali e-uric acid

IBurns CM, iWortmann RL. Izici zokwelashwa nokwelashwa kwe-gout. Ku: Firestein GS, Budd RC, Gabriel SE, McInnes IB, O'Dell JR, abahleli. Incwadi kaKelley noFirestein yeRheumatology. Umhlaka 10. IPhiladelphia, PA: Elsevier; 2017: isahluko 95.

Edwards NL. Crystal izifo sebethule. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-25. IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 273.

ISharfuddin AA, i-Weisbord SD, iPalevsky PM, iMolitoris BA. Ukulimala kanzima kwezinso. Ku: Skorecki K, Chertow GM, Marsden PA, Taal MW, Yu ASL, ama-eds. IBrenner neRector's The Kidney. Umhlaka 10. IPhiladelphia, PA: Elsevier; 2016: isahluko 31.