I-Acetylcholine receptor antibody

I-acetylcholine receptor antibody yiprotheni etholakala egazini labantu abaningi abane-myasthenia gravis. I-antibody ithinta ikhemikhali ethumela amasiginali kusuka emithanjeni kuya emisipheni naphakathi kwezinzwa ebuchosheni.

Lo mbhalo ukhuluma ngokuhlolwa kwegazi kwe-acetylcholine receptor antibody.

Kudingeka isampula yegazi. Isikhathi esiningi, igazi likhishwa emthanjeni ongaphakathi endololwaneni noma ngemuva kwesandla.

Isikhathi esiningi awudingi ukuthatha izinyathelo ezikhethekile ngaphambi kwalolu vivinyo.

Ungase uzwe ubuhlungu obuncane noma isitinyela lapho kufakwa inaliti. Ungase futhi uzizwe ushaywa yisiza ngemuva kokukhishwa kwegazi.

Lokhu kuhlolwa kusetshenziselwa ukuxilonga i-myasthenia gravis.

Imvamisa, ayikho i-acetylcholine receptor antibody (noma ngaphansi kuka-0.05 nmol / L) egazini.

Qaphela: Amabanga wamanani ajwayelekile angahluka kancane kumalabhorethri ahlukile. Khuluma nodokotela wakho mayelana nencazelo yemiphumela yakho ethile yokuhlolwa.

Isibonelo esingenhla sikhombisa isilinganiso esivamile semiphumela yalezi zivivinyo. Amanye ama-laboratories asebenzisa izilinganiso ezahlukahlukene noma angahlola izinhlobo ezahlukene.

Umphumela ongajwayelekile usho ukuthi i-acetylcholine receptor antibody itholakele egazini lakho. Iqinisekisa ukuxilongwa kwe-myasthenia gravis kubantu abanezimpawu. Cishe uhhafu wabantu abane-myasthenia gravis ekhawulelwe ezicutshini zamehlo abo (i-ocular myasthenia gravis) banalo leli gciwane elisegazini labo.

Kodwa-ke, ukuntuleka kwaleli antibody akuvimbeli i-myasthenia gravis. Cishe umuntu oyedwa kwabangu-5 one-myasthenia gravis abanazo izimpawu zaleli gciwane egazini labo. Umhlinzeki wakho angacabanga nokukuhlolela i-antibody ye-kinase (MuSK) antibody.

• Ukuhlolwa kwegazi
• Isistimu yezinzwa emaphakathi nesistimu yezinzwa ezungezayo

U-Evoli A, uVincent A. Ukuphazamiseka kokudluliswa kwe-neuromuscular. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-26. IPhiladelphia, PA: Elsevier; 2020: isahluko 394.

IPatterson ER, iWinters JL. IHemapheresis. Ku: McPherson RA, Pincus MR, abahleli. UHenry’s Clinical Diagnosis and Management by Laboratory Methods. Umhla ka-23. ISt Louis, MO: Elsevier; 2017: isahluko 37.