Ukuhlolwa kukaDonath-Landsteiner

Ukuhlolwa kweDonath-Landsteiner ukuhlolwa kwegazi ukuthola amasosha omzimba ayingozi ahlobene nesifo esingajwayelekile esibizwa nge-paroxysmal cold hemoglobinuria. La ma-antibody akha futhi aqede amaseli abomvu egazi lapho umzimba uvezwa amazinga okushisa abandayo.

Kudingeka isampula yegazi.

Akukho ukulungiselela okukhethekile okudingekayo.

Lapho inaliti ifakwa ukudonsa igazi, abanye abantu bezwa ubuhlungu obulinganiselayo. Abanye bazizwa beshaywa noma betinyelwa kuphela. Ngemuva kwalokho, kungahle kube nokushaywa okuthile noma ukulimazeka okuncane. Lokhu maduzane kuyaphela.

Lokhu kuhlolwa kwenziwa ukuqinisekisa ukuxilongwa kwe-paroxysmal cold hemoglobinuria.

Ukuhlolwa kuthathwa njengokujwayelekile uma engekho ama-antibody eDonath-Landsteiner akhona. Lokhu kubizwa ngomphumela ongemuhle.

Ububanzi bamanani ajwayelekile bungahluka kancane phakathi kwamalabhorethri ahlukene. Amanye amalebhu asebenzisa izilinganiso ezahlukahlukene noma avivinye amasampula ahlukile. Khuluma nomhlinzeki wakho wezokunakekelwa kwempilo mayelana nencazelo yemiphumela yakho ethile yokuhlolwa.

Imiphumela engajwayelekile isho ukuthi amasosha omzimba kaDonath-Landsteiner akhona. Lokhu kuyisibonakaliso se-paroxysmal abandayo hemoglobinuria.

Kunengozi encane ethintekayo ekuthatheni igazi lakho. Imithambo nemithambo yegazi kuyahluka ngosayizi komunye umuntu kuya kolunye uhlangothi lomzimba kuya kolunye. Ukuthatha igazi kwabanye abantu kungaba nzima kakhulu ukwedlula kwabanye.

Ezinye izingozi ezihambisana nokudonswa igazi zincane, kepha zingafaka:

• Ukopha ngokweqile
• Ukuquleka noma uzizwe unekhanda elincane
• Ukubhoboza okuningi ukuthola imithambo
• I-hematoma (i-blood buildup ngaphansi kwesikhumba)
• Ukutheleleka (ingozi encane noma kunini lapho isikhumba siphukile)

I-anti-P antibody; Paroxysmal abandayo hemoglobinuria - Donath-Landsteiner

I-Elghetany MT, iSchexneider KI, ukuphazamiseka kwe-Banki K. Erythrocytic. Ku: McPherson RA, Pincus MR, abahleli. UHenry’s Clinical Diagnosis and Management by Laboratory Methods. Umhla ka-23. ISt Louis, MO: Elsevier; I-2017: isahluko 32.

UMichel M. Autoimmune kanye ne-intravascular hemolytic anemias. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-26. IPhiladelphia, PA: Elsevier; 2020: isahluko 151.