ACTH ukuhlolwa kwegazi

Ukuhlolwa kwe-ACTH kukala izinga le-adrenocorticotropic hormone (ACTH) egazini. I-ACTH iyi-hormone ekhishwa endlala yobuchopho ebuchosheni.

Kudingeka isampula yegazi.

Udokotela wakho uzokucela ukuthi wenze isivivinyo kusesekuseni. Lokhu kubalulekile, ngoba izinga le-cortisol liyahlukahluka usuku lonke.

Ungatshelwa nokuthi uyeke ukuthatha imishanguzo engathinta imiphumela yokuhlolwa. Le mithi ifaka phakathi i-glucocorticoids efana ne-prednisone, hydrocortisone, noma i-dexamethasone. (Ungayeki le mithi ngaphandle uma eyalelwe ngumhlinzeki wakho.)

Lapho inaliti ifakwa ukudonsa igazi, abanye abantu bezwa ubuhlungu obulinganiselayo. Abanye bazizwa beshaywa noma betinyelwa kuphela. Ngemuva kwalokho, kungahle kube nokushaywa okuthile noma ukulinyazeka okuncane. Lokhu maduzane kuyaphela.

Umsebenzi omkhulu we-ACTH ukulawula i-cortisol ye-glucocorticoid (steroid). ICortisol ikhishwa yindlala ye-adrenal. Ilawula umfutho wegazi, ushukela wegazi, amasosha omzimba kanye nokuphendula kwengcindezi.

Lokhu kuhlolwa kungasiza ekutholeni izimbangela zezinkinga ezithile zehomoni.

Amanani ajwayelekile esampula yegazi athathwe ekuseni angu-9 kuye ku-52 pg / mL (2 kuye ku-11 pmol / L).

Ububanzi bamanani ajwayelekile bungahluka kancane phakathi kwamalabhorethri ahlukene. Amanye amalebhu asebenzisa izilinganiso ezahlukahlukene noma angahlola izinhlobo ezihlukile. Khuluma nodokotela wakho mayelana nencazelo yemiphumela yakho ethile yokuhlolwa.

Izinga eliphakeme kunokujwayelekile le-ACTH lingakhombisa:

• Izindlala ze-Adrenal azikhiqizi i-cortisol eyanele (isifo i-Addison)
• Izindlala ze-Adrenal azikhiqizi ama-hormone anele (i-congenital adrenal hyperplasia)
• Esinye noma eziningi zezindlala ze-endocrine zisebenza ngokweqile noma zenze isimila (izinhlobo eziningi ze-endocrine neoplasia type I)
• I-pituitary yenza i-ACTH (Cushing disease) eningi kakhulu, evame ukubangelwa isimila esingelona umdlavuza sendlala yamapayipi
• Uhlobo olungavamile lwesimila (amaphaphu, i-thyroid, noma amanyikwe) okwenza i-ACTH (ectopic Cushing syndrome) eningi kakhulu

Izinga eliphansi kunokujwayelekile le-ACTH lingakhombisa:

• Imithi ye-Glucocorticoid icindezela ukukhiqizwa kwe-ACTH (okuvame kakhulu)
• Indlala yamapayipi ayikhiqizi ama-hormone anele, njenge-ACTH (hypopituitarism)
• Isigaxa se-adrenal gland esikhiqiza i-cortisol eningi kakhulu

Kunengozi encane ethintekayo ekuthatheni igazi lakho. Imithambo nemithambo yegazi kuyahluka ngosayizi komunye umuntu kuya kolunye uhlangothi lomzimba kuya kolunye. Ukuthatha igazi kwabanye abantu kungaba nzima kakhulu ukwedlula kwabanye.

Ezinye izingozi ezihambisana nokudonswa igazi zincane kepha zingafaka:

• Ukopha ngokweqile
• Ukuquleka noma uzizwe unekhanda elincane
• Ukubhoboza okuningi ukuthola imithambo
• I-hematoma (ukuqoqwa kwegazi ngaphansi kwesikhumba)
• Ukutheleleka (ingozi encane noma kunini lapho isikhumba siphukile)

I-serum adrenocorticotropic hormone; I-hormone ye-Adrenocorticotropic; I-ACTH ezwela kakhulu

• Izindlala ze-Endocrine

IChernecky CC, iBerger BJ. Ihomoni ye-Adrenocorticotropic (ACTH, corticotropin) - serum. Ku: IChernecky CC, iBerger BJ, ama-eds. Ukuhlolwa Kwelabhoratri Nezinqubo Zokuxilonga. Umhlaka 6. ISt Louis, MO: Elsevier Saunders; 2013: 107.

I-Melmed S, i-Kleinberg D. Izixuku zamapayipi nezicubu. UMelmed S, uPolonsky KS, uLarsen PR, uKronenberg HM, ama-eds. Incwadi kaWilliams ye-Endocrinology. Umhlaka 13. IPhiladelphia, PA: Elsevier; 2016: isahluko 9.

UStewart PM, iNewell-Price JDC. I-adrenal cortex. Ku: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, abahleli. Incwadi kaWilliams ye-Endocrinology. Umhlaka 13. IPhiladelphia, PA: Elsevier; 2016: isahluko 15.