12 Kubuyekezwe Amaphilisi kanye Nezithasiselo Ezithandwayo Zokulahlekelwa Isisindo

-Delile

• 1.Garcinia Cambogia Khipha
• 2. I-Hydroxycut
• 3. Ikhafeyini
• 4. I-Orlistat (i-Alli)
• 5. Ama-Raspberry Ketone
• 6. Khipha Ubhontshisi KaKhofi Ohlaza Okotshani
• 7. IGlucomannan
• 8. IMeratrim
• 9. Khipha Itiye Eliluhlaza
• 10.Conjugated Linoleic Acid (CLA)
• 11. Forskolin
• 12. Umunyu Orenji / iSynephrine
• Imithi kadokotela
• Thatha Umlayezo Wekhaya

Sifaka imikhiqizo esicabanga ukuthi ilusizo kubafundi bethu. Uma uthenga ngezixhumanisi ezikuleli khasi, singathola ikhomishini encane. Nansi inqubo yethu.

Kunezisombululo eziningi ezahlukahlukene zokwehlisa isisindo laphaya.

Lokhu kufaka zonke izinhlobo zamaphilisi, izidakamizwa nezithako zemvelo.

Lokhu kuthiwa kukusiza ukwehlisa isisindo, noma okungenani kukwenze kube lula ukwehlisa isisindo kuhlangene nezinye izindlela.

Bavame ukusebenza ngenqubo eyodwa noma ngaphezulu:

1. Yehlisa isifiso sokudla, kukwenza uzizwe ugcwele ngokwengeziwe ukuze udle amakhalori ambalwa
2. Nciphisa ukumuncwa izakhamzimba ezinjengamafutha, zikwenza thatha ungenise amakhalori ambalwa
3. Khulisa ukushisa kwamafutha, ekwenza ukusha ama-calories amaningi

Nawa amaphilisi kanye nezengezo ezithandwa kakhulu zesisindo eziyi-12, ezibuyekezwa yisayensi.

1.Garcinia Cambogia Khipha

IGarcinia cambogia yaduma umhlaba wonke ngemuva kokuvezwa ohlelweni lukaDkt Oz e2012.

Yisithelo esincane, esiluhlaza okotshani, esimise okwethanga.

Isikhumba sesithelo siqukethe i-hydroxycitric acid (HCA). Lesi isithako esisebenzayo ku-garcinia cambogia extract, emakethwa njengephilisi lokudla.

Isebenza kanjani: Izifundo zezilwane zikhombisa ukuthi ingavimbela i-enzyme ekhiqiza amafutha emzimbeni futhi inyuse amazinga e-serotonin, engasiza ekunciphiseni izifiso (1,).

Ukusebenza kahle: Isifundo esisodwa nabantu abayi-130 siqhathanisa i-garcinia nephilisi le-dummy. Kwakungekho mehluko ngesisindo noma ngamaphesenti amafutha emzimbeni phakathi kwamaqembu (3).

Ukubuyekezwa kuka-2011 okwakubheka izifundo eziyi-12 kwi-garcinia cambogia kwathola ukuthi, ngokwesilinganiso, kwabangela ukwehla kwesisindo cishe samakhilogremu ama-2 (0.88 kg) emasontweni ambalwa (4).

Okuqhamuka uma udla imishanguzo: Ayikho imibiko yemiphumela emibi kakhulu, kepha eminye imibiko yezinkinga zokugaya ukudla emnene.

Ngezansi:

Noma i-garcinia cambogia ingadala ukulahleka kwesisindo okuthobekile, imiphumela incane kakhulu kangangokuthi mhlawumbe ngeke ize ibonakale.

2. I-Hydroxycut

IHydroxycut sekunesikhathi esingaphezu kweminyaka eyishumi ikhona, futhi njengamanje ingenye yezithako ezithandwa kakhulu zokuncipha emhlabeni.

Kunezinhlobo ezahlukahlukene ezahlukahlukene, kepha okuvame kakhulu ukubizwa nje nge- "Hydroxycut."

Isebenza kanjani: Iqukethe izithako ezimbalwa okuthiwa zisiza ekwehliseni isisindo, kufaka phakathi i-caffeine kanye nezitshalo ezimbalwa zezitshalo.

Ukusebenza kahle: Olunye ucwaningo lukhombisile ukuthi kubangele ama-21 lbs (9.5 kg) wokulahleka kwesisindo esikhathini esiyizinyanga ezi-3 (5).

Okuqhamuka uma udla imishanguzo: Uma uzwela nge-caffeine, ungahle uzwe ukukhathazeka, ukuqina, ukuthuthumela, isicanucanu, isifo sohudo nokucasuka.

Ngezansi:

Ngeshwa, kunesifundo esisodwa kuphela kulesi sengezo futhi akukho datha yokusebenza kwesikhathi eside. Ucwaningo olwengeziwe luyadingeka.

3. Ikhafeyini

I-caffeine yinto edliwa kakhulu e-psychoactive emhlabeni ().

Itholakala ngokwemvelo kukhofi, itiye eliluhlaza kanye noshokoledi omnyama, futhi ingezwe ekudleni naseziphuzweni eziningi ezicutshunguliwe.

I-Caffeine iyisikhuthazi esaziwa kakhulu se-metabolism, futhi ivame ukungezwa kwizengezo zokunciphisa isisindo.

Isebenza kanjani: Izifundo zesikhashana esifushane zikhombisile ukuthi i-caffeine ingakhuphula imetabolism ngo-3-11%, futhi inyuse ukushiswa kwamafutha kufika kuma-29% (,, 9, 10).

Ukusebenza kahle: Kukhona futhi ezinye izifundo ezibonisa ukuthi i-caffeine ingadala ukwehlisa isisindo kubantu (,).

Okuqhamuka uma udla imishanguzo: Kwabanye abantu, inani eliphakeme le-caffeine lingadala ukukhathazeka, ukuqwasha, ukuqina, ukucasuka, isicanucanu, isifo sohudo nezinye izimpawu. I-caffeine nayo iyalutha futhi inganciphisa ikhwalithi yokulala kwakho.

Asikho ngempela isidingo sokuthatha isengezo noma iphilisi eline-caffeine kulo. Imithombo engcono kakhulu ikhofi esezingeni eliphakeme netiye eluhlaza, nayo enama-antioxidants nezinye izinzuzo zezempilo.

Ngezansi:

I-caffeine ingakhuphula umzimba futhi ithuthukise ukushiswa kwamafutha esikhathini esifushane. Kodwa-ke, ukubekezelela imiphumela kungakhula ngokushesha.

4. I-Orlistat (i-Alli)

I-Orlistat isidakamizwa esisebenza ngemithi, esithengiswa ngaphezu kwekhawunta ngaphansi kwegama elithi Alli, nangaphansi kwesidakamizwa njenge-Xenical.

Isebenza kanjani: Le pilisi yokwehlisa isisindo isebenza ngokuvimbela ukonakala kwamafutha emathunjini, ikwenze uthathe amakhalori ambalwa emafutheni.

Ukusebenza kahle: Ngokuya ngokubuyekezwa okukhulu kwezifundo eziyi-11, i-orlistat ingakhuphula ukwehla kwesisindo ngamakhilogremu ama-6 (2.7 kg) ngokuqhathaniswa nepilisi yedummy ().

Ezinye izinzuzo: I-Orlistat ikhonjisiwe ukuthi inciphisa umfutho wegazi kancane, futhi yehlise ubungozi bokuthola uhlobo lwesifo sikashukela sohlobo lwe-2 ngama-37% ocwaningweni olulodwa (,).

Okuqhamuka uma udla imishanguzo: Lesi sidakamizwa sinemiphumela emibi eminingi yokugaya ukudla, kufaka phakathi okungaxegi, indle enamafutha, ukuqumba, ukuhamba kwamathumbu kaningi okunzima ukuwalawula, nokunye. Kungaphinde kube nomthelela ekushodeni kwamavithamini ancibilika njengamafutha, njengamavithamini A, D, E noK.

Imvamisa kunconywa ukuthi ulandele ukudla okunamafutha aphansi ngenkathi uthatha i-orlistat, ukuze unciphise imiphumela emibi.

Kuyathakazelisa ukuthi ukudla okuphansi kwe-carb (ngaphandle kwezidakamizwa) kukhonjisiwe ukuthi kusebenza njengokubili kwe-orlistat kanye nokudla okunamafutha aphansi kuhlangene (16).

Ngezansi:

I-Orlistat, eyaziwa nangokuthi i-Alli noma i-Xenical, inganciphisa inani lamafutha owadonsa ekudleni futhi ikusize wehlise isisindo. Inemiphumela emibi eminingi, eminye yayo engemnandi neze.

5. Ama-Raspberry Ketone

I-raspberry ketone yinto etholakala kuma-raspberries, enesibopho sephunga lawo elihlukile.

Uhlobo lokwenziwa lwama-raspberry ketone luthengiswa njengesengezo sokulahlekelwa isisindo.

Isebenza kanjani: Emangqamuzaneni amafutha angawodwa avela kumagundane, ama-raspberry ketone andisa ukuwohloka kwamafutha futhi andise amazinga e-hormone ebizwa ngokuthi i-adiponectin, okukholakala ukuthi ihlobene nokuncipha ().

Ukusebenza kahle: Asikho isifundo esisodwa kuma-raspberry ketone kubantu, kepha isifundo esisodwa samagundane sisebenzisa imithamo emikhulu sikhombisile ukuthi sinciphise ukuzuza kwesisindo ().

Okuqhamuka uma udla imishanguzo: Kungadala ukuthi imivimbo yakho iphunga njengama-raspberry.

Ngezansi:

Abukho ubufakazi bokuthi ama-raspberry ketones abangela ukuncipha kubantu, futhi izifundo zamagundane ezibonisa ukuthi zisebenza zisebenzise imithamo emikhulu.

6. Khipha Ubhontshisi KaKhofi Ohlaza Okotshani

Ubhontshisi wekhofi oluhlaza umane ubhontshisi ojwayelekile wekhofi ongakaze wosa.

Ziqukethe izinto ezimbili okukholelwa ukuthi ziyasiza ekwehliseni isisindo, i-caffeine ne-chlorogenic acid.

Isebenza kanjani: I-caffeine ingakhuphula ukushisa kwamafutha, futhi i-chlorogenic acid inganciphisa ukonakala kwama-carbohydrate esiswini.

Ukusebenza kahle: Izifundo ezimbalwa zabantu zikhombisile ukuthi okukhishwe ubhontshisi wekhofi oluhlaza kungasiza abantu ukunciphisa umzimba (,).

Ukubuyekezwa kwezifundo ezi-3 kutholakale ukuthi ibhekwa yenze ukuthi abantu banciphise amanye amakhilogremu angu-5.4 (2.5 kg) kune-placebo, iphilisi ledummy ().

Ezinye izinzuzo: Ukukhishwa kukabhontshisi okuluhlaza kungasiza ekwehliseni amazinga kashukela egazini, futhi kunciphise umfutho wegazi. Iphinde ibe ne-antioxidants ephezulu (,,,).

Okuqhamuka uma udla imishanguzo: Kungadala imiphumela emibi efanayo ne-caffeine. I-chlorogenic acid ekuyo nayo ingadala nohudo, kanti abanye abantu bangazwani nobhontshisi wekhofi oluhlaza ().

Ngezansi:

Ukukhishwa kukabhontshisi okuluhlaza kungadala ukwehla kwesisindo okuncane, kepha khumbula ukuthi izifundo eziningi zazixhaswe yimboni.

7. IGlucomannan

IGlucomannan uhlobo lwefayibha etholakala ezimpandeni ze-elephant yam, ebizwa nangokuthi i-konjac.

Isebenza kanjani: IGlucomannan imunca amanzi bese iba njengejeli. "Ihlala" esiswini sakho futhi ikhuthaze umuzwa wokugcwala, ikusize udle amakhalori ambalwa (27).

Ukusebenza kahle: Izifundo ezintathu zabantu zikhombisile ukuthi i-glucomannan, ehlanganiswe nokudla okunempilo, ingasiza abantu ukuthi banciphise amakhilogremu angu-8-10 (3.6-4.5 kg) wesisindo emasontweni ama-5 ().

Ezinye izinzuzo: IGlucomannan iyi-fiber engondla amabhaktheriya anobungane emathunjini. Inganciphisa noshukela wegazi, i-cholesterol egazini kanye ne-triglycerides, futhi isebenza kahle kakhulu ekuqunjelweni (,,).

Okuqhamuka uma udla imishanguzo: Kungadala ukuqunjelwa, ukuqothuka kanye nezitulo ezithambile, futhi kungaphazamisa eminye imithi yomlomo uma ithathwa ngasikhathi sinye.

Kubalulekile ukuthatha i-glucomannan cishe isigamu sehora ngaphambi kokudla, nengilazi yamanzi. Uma ungathanda ukuyizama, i-Amazon inokukhetha okuhle okutholakalayo.

Ungathola ukubuyekezwa kwenhloso ye-glucomannan kule ndatshana.

Ngezansi: Ucwaningo luhlala lukhombisa ukuthi i-fiber glucomannan, uma ihlanganiswe nokudla okunempilo, ingasiza abantu ukunciphisa umzimba. Iphinde iholele ekuthuthukisweni kwezimpawu ezahlukahlukene zezempilo.

8. IMeratrim

UMeratrim ungumuntu osondelene naye emakethe yamaphilisi okudla.

Kuyinhlanganisela yezitshalo ezimbili zezitshalo ezingaguqula imetabolism yamaseli amafutha.

Isebenza kanjani: Kuthiwa kwenza kube nzima ngamangqamuzana anamafutha ukuba ande, anciphise inani lamafutha abawacosha egazini, futhi abasize bashise amanoni agciniwe.

Ukusebenza kahle: Kuze kube manje, kwenziwe ucwaningo olulodwa eMeratrim. Bangu-100 abantu abakhuluphele kakhulu ababekwa ekudleni okuqinile kwamakhalori angama-2000, kungaba yiMeratrim noma iphilisi le-dummy (32).

Ngemuva kwamasonto ayisishiyagalombili, iqembu leMeratrim lase lehle ngamakhilogremu ayi-5.2 kg kanye no-4.7 cm (11.9 cm) okhalweni lwabo. Futhi babenezinga lempilo elithuthukisiwe futhi banciphisa ushukela wegazi, i-cholesterol kanye ne-triglycerides.

Okuqhamuka uma udla imishanguzo: Ayikho imiphumela emibi ebikiwe.

Ukubuyekezwa okuningiliziwe kweMeratrim, funda le ndatshana.

Ngezansi:

Ucwaningo oluthile lukhombisile ukuthi iMeratrim idale ukwehla kwesisindo futhi inezinye izinzuzo eziningi zezempilo. Kodwa-ke, lolu cwaningo lwaluxhaswe yimboni futhi kudingeka olunye ucwaningo.

9. Khipha Itiye Eliluhlaza

I-green tea extract iyisithako esidumile kuzithasiselo eziningi zokulahlekelwa isisindo.

Lokhu kungenxa yokuthi ucwaningo oluningi lukhombisile i-antioxidant eyinhloko ekulo, i-EGCG, ukusiza ukushiswa kwamafutha.

Isebenza kanjani: Ukukhishwa kwetiye eluhlaza kukholakala ukuthi kukhulisa umsebenzi we-norepinephrine, i-hormone ekusiza ukuthi ushise amanoni (33).

Ukusebenza kahle: Izifundo eziningi zabantu zikhombisile ukuthi ukukhishwa kwetiye eluhlaza kungandisa ukushisa kwamafutha futhi kubangele ukulahleka kwamafutha, ikakhulukazi endaweni yesisu (,,, 37).

Okuqhamuka uma udla imishanguzo: I-green tea extract ngokuvamile ibekezeleleka kahle. Iqukethe i-caffeine, futhi ingadala izimpawu kubantu abane-caffeine ezwelayo.

Ngokwengeziwe, zonke izinzuzo zezempilo zokuphuza itiye eliluhlaza kufanele zisebenze nasokhisweni lwetiye eluhlaza.

Ngezansi: Itiye elihlaza kanye netiye eluhlaza kungakhuphula ukushisa kwamafutha kancane, futhi kungakusiza ukuthi ulahlekelwe ngamafutha esiswini.

10.Conjugated Linoleic Acid (CLA)

I-linoleic acid ehlanganisiwe, noma i-CLA, ibilokhu iyisengezo esidumile sokulahleka kwamafutha iminyaka.

Ingenye yamafutha “okunempilo” e-trans, futhi itholakala ngokwemvelo kokunye ukudla kwezilwane okunamafutha njengoshizi nebhotela.

Isebenza kanjani: I-CLA inganciphisa isifiso sokudla, ikhulise imetabolism futhi ikhuthaze ukonakala kwamafutha omzimba (,).

Ukusebenza kahle: Ekubuyekezweni okukhulu kwezifundo ezi-18 ezahlukahlukene, i-CLA idale ukwehla kwesisindo cishe kwama-0.2 amakhilogremu (0.1 kg) ngesonto, izinyanga ezifika kwezingu-6 ().

Ngokuya kolunye ucwaningo lokubuyekeza kusuka ku-2012, i-CLA ingakwenza ulahlekelwe isisindo esingama-3 lbs (1.3 kg), uma kuqhathaniswa nepilisi yedummy ().

Okuqhamuka uma udla imishanguzo: I-CLA ingadala imiphumela emibi yokugaya ukudla ehlukahlukene, futhi ingaba nemiphumela emibi esikhathini eside, okungahle kube nomthelela esibindini esinamafutha, ukumelana ne-insulin kanye nokuvuvukala okwandayo.

Ngezansi:

I-CLA iyisengezo esisebenzayo sokulahleka kwesisindo, kepha ingaba nemiphumela emibi esikhathini eside. Inani elincane lokwehlisa isisindo alifanele ingozi.

11. Forskolin

I-Forskolin ikhishwe esitshalweni emndenini we-mint, okuthiwa iyasebenza ekunciphiseni isisindo.

Isebenza kanjani: Kukholakala ukuthi kukhulisa amazinga enkomponi ngaphakathi kwamaseli abizwa nge-cAMP, angahle avuse ukushiswa kwamafutha ().

Ukusebenza kahle: Ucwaningo olulodwa kumadoda angama-30 abakhuluphele nabakhuluphele kakhulu lukhombisile ukuthi i-forskolin inciphise amafutha omzimba futhi yenyusa isisindo semisipha, ngenkathi ingenamphumela osindayo. Olunye ucwaningo kwabesifazane abangama-23 abakhuluphele kakhulu alutholanga miphumela (43,).

Okuqhamuka uma udla imishanguzo: Kunemininingwane elinganiselwe kakhulu ekuphepheni kwalesi sengezo, noma ubungozi bemiphumela emibi.

Ngezansi:

Lezi zifundo ezimbili ezincane ze-forskolin zibonise imiphumela ephikisanayo. Kungcono ukugwema lesi sithasiselo kuze kube kwenziwa olunye ucwaningo.

12. Umunyu Orenji / iSynephrine

Uhlobo lwewolintshi olubizwa ngokuthi i-orange elibabayo luqukethe i-synephrine eyakhiwe.

I-Synephrine ihlobene ne-ephedrine, ebikade iyisithako esithandwayo ekwakhiweni kwamaphilisi okwehlisa isisindo ahlukahlukene.

Kodwa-ke, i-ephedrine selokhu yavinjelwa njengesithako sokulahlekelwa isisindo yi-FDA ngenxa yemiphumela emibi kakhulu.

Isebenza kanjani: USynephrine wabelana ngezindlela ezifanayo ne-ephedrine, kepha ayinamandla kangako. Kunganciphisa ukudla futhi kukhulise kakhulu ukushiswa kwamafutha ().

Ukusebenza kahle: Zimbalwa kakhulu izifundo ezenziwe ku-synephrine, kepha i-ephedrine ikhonjisiwe ukuthi ibangele ukuncipha kwesisindo esifushane kwezifundo eziningi ().

Okuqhamuka uma udla imishanguzo: Njenge-ephedrine, i-synephrine ingaba nemiphumela emibi kakhulu ehlobene nenhliziyo. Kungase futhi kube umlutha.

Ngezansi:

I-Synephrine iyisikhuthazi esinamandla, futhi mhlawumbe iyasebenza ekunciphiseni isisindo esikhathini esifushane. Kodwa-ke, imiphumela emibi ingaba mibi, ngakho-ke lokhu kufanele kusetshenziswe kuphela ngokuqapha okukhulu.

Imithi kadokotela

Ngokwengeziwe, kunamaphilisi amaningi kadokotela okwehlisa isisindo akhonjiswe ukuthi ayasebenza.

Okuvame kakhulu yi-Contrave, Phentermine, ne-Qsymia.

Ngokuya ngocwaningo lwamuva lwango-2014 lokubuyekeza, ngisho namaphilisi okuncipha kwesisindo kadokotela awasebenzi ngendlela ongathemba ngayo.

Ngokwesilinganiso, zingakusiza ukuthi ulahlekelwe yisisindo somzimba esifinyelela ku-3-9% ngokuqhathaniswa nephilisi ledamu (47).

Khumbula ukuthi lokhu kuphela lapho kuhlangene ngokudla okunomsoco okunempilo. Azisebenzi ngokwazo, futhi akusona neze isisombululo sokukhuluphala.

Ingasaphathwa imiphumela yabo emibi eminingi.

UKUHOXISWA KWEBELVIQNgoFebhuwari 2020, i-Food and Drug Administration (FDA) yacela ukuthi i-lorcaserin (Belviq) yesisindo sokulahla isisindo isuswe emakethe yase-U.S. Lokhu kungenxa yokwanda kwamacala omdlavuza kubantu abathathe iBelviq ngokuqhathaniswa ne-placebo. Uma unqunyelwe noma uthatha uBelviq, yeka ukuthatha lesi sidakamizwa bese ukhuluma nomhlinzeki wakho wezokunakekelwa kwempilo mayelana namanye amasu wokulawulwa kwesisindo.

Funda kabanzi ngokuhoxa nalapha.

Thatha Umlayezo Wekhaya

Kuma-12, laba bangabanqobi abasobala, ngobufakazi obuqine kakhulu bokubaxhasa:

• Ukwehla kwesisindo: IGlucomannan, i-CLA ne-Orlistat (i-Alli)
• Ukushisa okukhulu kwamafutha: Okukhishwe nge-caffeine netiye eliluhlaza

Kodwa-ke, kufanele ngeluleke ngokumelene ne-Orlistat ngenxa yemiphumela emibi, kanye ne-CLA ngenxa yemiphumela emibi empilweni ye-metabolic.

Lokho kusishiya ne-glucomannan, i-green tea extract ne-caffeine.

Lezi zithasiselo kungaba njalo iwusizo, kepha imiphumela inesizotha kakhulu.

Ngeshwa, AKUKHO ukwengeza noma iphilisi elisebenza kahle kakhulu ekunciphiseni isisindo.

Bangakunikeza ukugaya umzimba kancane futhi bakusize ulahlekelwe amakhilogremu ambalwa, kepha kulapho kuphela khona, ngeshwa.

Ukusika ama-carbs nokudla amaprotheni amaningi kuseyizindlela ezingcono kakhulu zokwehlisa isisindo, futhi kusebenza kangcono kunawo wonke amaphilisi okudla ahlanganisiwe.