INevirapine

-Delile

• Ngaphambi kokuthatha i-nevirapine,
• INevirapine ingadala imiphumela emibi. Tshela udokotela wakho uma enye yalezi zimpawu inzima noma ingapheli:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

INevirapine ingadala ukulimala kwesibindi okunzima, okusongela impilo, ukusabela kwesikhumba, kanye ne-allergen reaction. Tshela udokotela wakho uma uke waba nesifo sesibindi noma wake waba naso, ikakhulukazi i-hepatitis B noma u-C. Udokotela wakho mhlawumbe uzokutshela ukuthi ungaphuzi i-nevirapine. Phinda utshele udokotela wakho uma unamaqubu noma esinye isimo sesikhumba ngaphambi kokuba uqale ukuthatha i-nevirapine. Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo, yeka ukuthatha i-nevirapine bese ushayela udokotela wakho ngokushesha: ukuqubuka, ikakhulukazi uma kunzima noma kuza nezinye izimpawu ezikulolu hlu; ukukhathala ngokweqile; ukungabi namandla noma ubuthakathaka obujwayelekile; isicanucanu; ukuhlanza; ukulahlekelwa ukudla; umchamo omnyama (onemibala yetiye); indle ephaphathekile; ukuphuzi kwesikhumba noma kwamehlo; ubuhlungu engxenyeni engenhla yangakwesokudla yesisu; umkhuhlane, umphimbo obuhlungu, amakhaza, noma ezinye izimpawu zokutheleleka; izimpawu ezinjengomkhuhlane; ubuhlungu bemisipha noma obuhlangene; amabhamuza; izilonda zomlomo; amehlo abomvu noma avuvukile; isifuba; ukulunywa; ukuvuvukala kobuso, umphimbo, ulimi, izindebe, amehlo, izandla, izinyawo, amaqakala noma imilenze engezansi; ukushaqeka; noma ukuphefumula kanzima noma ukugwinya.

Uma udokotela wakho ekutshela ukuthi uyeke ukuthatha i-nevirapine ngoba unesikhumba esibi noma ukusabela kwesibindi, akufanele uphinde uthathe i-nevirapine futhi.

Udokotela wakho uzokuqala ngomthamo ophansi we-nevirapine futhi akhuphule umthamo wakho ngemuva kwezinsuku eziyi-14. Lokhu kuzonciphisa ubungozi bokuthi uzoba nokuphendula okungathi sína kwesikhumba. Uma uba nanoma yiluphi uhlobo lokuqubuka noma yiziphi izimpawu ezibalwe ngenhla ngenkathi uthatha umthamo ophansi we-nevirapine, shayela udokotela wakho ngokushesha. Musa ukwandisa umthamo wakho kuze kube yilapho ukuqhuma noma izimpawu zakho sezihambile.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile ukuze ahlole impendulo yomzimba wakho ku-nevirapine, ikakhulukazi phakathi namasonto okuqala ayi-18 okwelashwa kwakho.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yeziguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa nge-nevirapine futhi isikhathi ngasinye lapho ugcwalisa umuthi wakho. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungathola futhi iMihlahlandlela Yezokwelapha kwiwebhusayithi ye-FDA: http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm.

Khuluma nodokotela wakho ngezingozi zokuphuza i-nevirapine. Kunobungozi obukhulu bokuthi uzohlaselwa ukulimala kwesibindi ngesikhathi sokwelashwa kwakho uma ungowesifazane futhi uma unesibalo esiphezulu se-CD4 (inani elikhulu lohlobo oluthile lokutheleleka okulwa neseli egazini lakho).

INevirapine isetshenziswa kanye neminye imithi yokwelapha ukutheleleka ngegciwane lesandulela ngculazi (i-HIV) kubantu abadala nasezinganeni ezinezinsuku eziyi-15 nangaphezulu. INevirapine akufanele isetshenziselwe ukwelapha abasebenzi bezokunakekelwa kwempilo noma abanye abantu abachayeke ekuthelelekeni nge-HIV ngemuva kokuthintana negazi, izicubu, noma olunye uketshezi lomzimba olonakele. INevirapine ikusigaba semithi esibizwa nge-non-nucleoside reverse transcriptase inhibitors (NNRTIs). Isebenza ngokunciphisa inani le-HIV egazini. Yize i-nevirapine ingayelaphi i-HIV, ingahle inciphise amathuba akho okuba ne-immunodeficiency syndrome (i-AIDS) kanye nezifo ezihlobene ne-HIV ezinjengezifo ezibucayi noma umdlavuza. Ukuthatha le mithi kanye nokwenza ucansi oluphephile nokwenza ezinye izinguquko endleleni yokuphila kunganciphisa ubungozi bokudlulisela (ukusabalalisa) igciwane le-HIV kwabanye abantu.

INevirapine iza njengethebhulethi, ithebhulethi ekhishwa isikhathi eside, kanye nokumiswa (uketshezi) ukuthatha ngomlomo noma ngaphandle kokudla. Ithebhulethi nokumiswa kuvame ukuthathwa kanye ngosuku amasonto ama-2 bese kuthi kabili ngosuku ngemuva kwamasonto amabili okuqala. Ithebhulethi ekhishwa isikhathi eside ithathwa kanye ngosuku, kulandela ukwelashwa okungenani amasonto amabili ngamaphilisi ejwayelekile e-nevirapine noma ukumiswa. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-nevirapine njengoba nje iyalelwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Gwinya i-nevirapine eneziphuzo ezinjengamanzi, ubisi noma isoda.

Gwinya wonke amaphilisi akhululiwe; ungawahlukanisi, ungawahlafune noma uwagxoze.

Nyakazisa uketshezi ngobumnene ngaphambi kokusebenzisa ngakunye ukuxuba umuthi ngokulinganayo. Sebenzisa inkomishi yokulinganisa ngomlomo noma isirinji yokulinganisa ukuze ulinganise umthamo wakho. Kungcono ukusebenzisa isipontsho, ikakhulukazi uma umthamo wakho ungaphansi kwama-5 mL (1 ithisipuni). Uma usebenzisa inkomishi yokufaka umthamo, qala uphuze yonke imithi oyilinganise enkomishini yokulinganisa. Bese ugcwalisa inkomishi yokufaka umthamo ngamanzi bese uphuza amanzi ukuze uqiniseke ukuthi uthola umthamo wakho ogcwele.

INevirapine ingayilawula i-HIV kepha ngeke iyelaphe. Qhubeka uphuze i-nevirapine noma ngabe uzizwa uphilile. Ungayeki ukuphuza i-nevirapine noma yimuphi omunye umuthi owuthathayo ukwelapha i-HIV noma i-AIDS ngaphandle kokukhuluma nodokotela wakho. Udokotela wakho mhlawumbe uzokutshela ukuthi uyeke ukuthatha imishanguzo yakho ngendlela ethile. Uma uphuthelwa imithamo noma uyeka ukuthatha i-nevirapine, isimo sakho singaba nzima ukwelashwa.

Uma ungaphuzi i-nevirapine izinsuku eziyi-7 noma ngaphezulu, ungaqali ukuyithatha futhi ngaphandle kokukhuluma nodokotela wakho. Udokotela wakho uzokuqala ngomthamo ophansi we-nevirapine, futhi akhuphule umthamo wakho ngemuva kwamasonto amabili.

INevirapine kwesinye isikhathi isetshenziselwa ukuvikela izingane ezingakazalwa omama bazo abane-HIV noma i-AIDS ekutheleleni nge-HIV ngesikhathi sokubeletha.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-nevirapine,

• Tshela udokotela kanye nosokhemisi wakho uma unegciwane ku-nevirapine noma eminye imithi.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, kanye nezithako zokudla okunomsoco okwenzayo. Qiniseka ukuthi usho noma yikuphi kokulandelayo: ama-anticoagulants (’ama-thinner egazi’) njenge-warfarin (i-Coumadin); ama-antifungal athile afana ne-fluconazole (i-Diflucan), i-itraconazole (i-Sporanox), i-ketoconazole (i-Nizoral), ne-voriconazole (i-Vfend); amaphilisi okulawula ukubeletha uma uwaphuza ngenxa yezizathu ezingezona ezokuvimbela ukukhulelwa; ama-calcium channel blocker afana ne-diltiazem (Cardizem, Dilacor, Tiazac), nifedipine (Adalat, Procardia), ne-verapamil (Calan, Covera, Isoptin, Verelan); i-clarithromycin (i-Biaxin); imishanguzo ethile yokwelashwa ngamakhemikhali njenge-cyclophosphamide (i-cytoxan); i-cisapride (i-Propulsid); i-cyclosporine (iNeoral, iSandimmune); i-ergot alkaloids efana ne-ergotamine (i-Cafergot, i-Ercaf, abanye); i-fentanyl (iDuragesic, i-Actiq); imithi yokushaya kwenhliziyo okungajwayelekile njenge-amiodarone (Cordarone) ne-disopyramide (iNorpace); imishanguzo yokubanjwa njenge-carbamazepine (Tegretol), i-clonazepam (iKlonopin), ne-ethosuximide (iZarontin); i-methadone (i-Dolophine), eminye imishanguzo ye-HIV noma i-AIDS njenge-amprenavir (Agenerase), atazanavir (Reyataz), efavirenz (Sustiva), fosamprenavir (Lexiva), indinavir (Crixivan), lopinavir kanye ne-ritonavir inhlanganisela (Kaletra), nelfinavir (Viracept) , ne-saquinavir (i-Fortovase, i-Invirase); i-prednisone (iDeltasone); i-rifabutin (i-Mycobutin); i-rifampin (i-Rifadin, i-Rimactane); i-sirolimus (i-Rapamune); ne-tacrolimus (i-Prograf). Eminye imithi eminingi ingaxhumana ne-nevirapine, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• utshele udokotela wakho kanye nosokhemisi ukuthi yimiphi imikhiqizo yamakhambi oyithathayo, ikakhulukazi iSort John's wort.
• Tshela udokotela wakho uma uke waba nesifo sezinso noma wake waba naso, ikakhulukazi uma welashwa nge-dialysis (ukwelashwa ukuhlanza igazi ngaphandle komzimba lapho izinso zingasebenzi kahle).
• utshele udokotela wakho uma ukhulelwe noma uhlela ukukhulelwa. Uma ukhulelwa ngenkathi uthatha i-nevirapine, shayela udokotela wakho. Akufanele uncelise ibele uma utheleleke nge-HIV noma uphuza i-nevirapine.
• kufanele wazi ukuthi lo muthi unganciphisa ukuzala kwabesifazane. Khuluma nodokotela wakho ngezingozi zokuthatha lo muthi uma unezinkinga mayelana nokuzala.
• kufanele wazi ukuthi amafutha omzimba wakho angakhuphuka noma ahambele kwezinye izindawo zomzimba wakho njengokhalo lwakho, iqolo elingaphezulu, intamo (’’ inyathi hump ’’), amabele, nasesizungeze isisu sakho. Ungaqaphela ukulahleka kwamafutha omzimba ebusweni bakho, emilenzeni nasezingalweni.
• kufanele wazi ukuthi ngenkathi uthatha imishanguzo yokwelapha ukutheleleka nge-HIV, amasosha omzimba wakho angaqina futhi aqale ukulwa nezinye izifo ezazivele zisemzimbeni wakho noma zidale ukuthi ezinye izimo zivele. Lokhu kungadala ukuthi uthuthukise izimpawu zalezo zifo noma izimo. Uma unezimpawu ezintsha noma eziya ziba zimbi phakathi nokwelashwa kwakho nge-nevirapine, qiniseka ukuthi utshela udokotela wakho.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

INevirapine ingadala imiphumela emibi. Tshela udokotela wakho uma enye yalezi zimpawu inzima noma ingapheli:

• ikhanda
• isifo sohudo
• ubuhlungu besisu

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi izimpawu ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• ukuvuvukala kwezandla, izinyawo, amaqakala, noma imilenze engezansi
• amaqhubu abomvu abuhlungu esikhunjeni
• ukukhathala ngokweqile
• imfiva
• ikhanda
• ubunzima bokulala noma ukulala
• isicanucanu
• ukuhlanza
• ukuqubuka
• isiyezi

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Uma uthatha amaphilisi akhululiwe, ungaqaphela okuthile okubukeka njengethebhulethi kusitulo sakho. Leli igobolondo nje elingenalutho lethebhulethi, futhi lokhu akusho ukuthi awutholanga umthamo wakho ophelele wemithi.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Viramune^®
• I-Viramune^® XR