Zolmitriptan
-Delile
- Ngaphambi kokuthatha i-zolmitriptan,
- I-Zolmitriptan ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
- Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
- Izimpawu zokudlula ngokweqile zingafaka:
I-Zolmitriptan isetshenziselwa ukwelapha izimpawu zekhanda elibuhlungu (ikhanda elibuhlungu elibuhlungu kwesinye isikhathi elihambisana nesicanucanu nokuzwela komsindo nokukhanya). UZolmitriptan usesigabeni semithi ebizwa ngama-serotonin receptor agonists akhethiwe. Isebenza ngokunciphisa imithambo yegazi ezungeze ubuchopho, imise amasignali obuhlungu ukuthi angathunyelwa ebuchosheni, futhi ivimbele ukukhishwa kwezinto ezithile zemvelo ezibangela ubuhlungu, isicanucanu, nezinye izimpawu ze-migraine. I-Zolmitriptan ayivimbeli ukuhlaselwa yi-migraine noma inciphise inani lekhanda onalo.
I-Zolmitriptan iza njengethebhulethi kanye nethebhulethi ehlukaniswa ngomlomo (ithebhulethi encibilika ngokushesha emlonyeni) ukuthatha ngomlomo. Kuvame ukuthathwa kusibonakaliso sokuqala sekhanda le-migraine. Uma izimpawu zakho ziba ngcono ngemuva kokuthatha i-zolmitriptan kodwa ubuye ngemuva kwamahora ama-2 noma ngaphezulu, ungathatha ithebhulethi yesibili. Kodwa-ke, uma izimpawu zakho zingathuthuki ngemuva kokuthatha i-zolmitriptan, ungathathi ithebhulethi yesibili ngaphandle kokubiza udokotela wakho. Udokotela wakho uzokutshela inani eliphakeme lamaphilisi noma amaphilisi ahlukaniswe ngomlomo ongawathatha esikhathini samahora angama-24. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-zolmitriptan njengoba nje kuyalelwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.
Ungathatha umthamo wakho wokuqala we-zolmitriptan ehhovisi likadokotela noma kwesinye isikhungo sezokwelapha lapho ungabhekwa khona ukusabela okungathi sína.
Uma udokotela wakho enqume umthamo ongaphansi kuka-2.5 mg, ungasebenzisa iminwe yakho ukuphula ithebhulethi engu-2.5-mg kulayini oyihlukanisa phakathi. Kodwa-ke, akufanele wephule noma uhlukanise ithebhulethi ehlukaniswa ngomlomo.
Ukuze uthathe ithebhulethi ehlakazeka ngomlomo, sebenzisa izandla ezomile ukukhipha emuva ukupakisha kwe-foil. Khipha ngokushesha ithebhulethi bese uyibeka olimini lwakho. Ithebhulethi izoncibilika ngokushesha futhi ingagwinywa ngamathe. Awekho amanzi adingekayo ukugwinya amaphilisi ahlukanisayo. Ungavuli ukupakisha kwe-foil noma ususe ithebhulethi ehlukaniswa ngomlomo kuze kube yilapho usulungele ukuyithatha.
Shayela udokotela wakho uma ikhanda lakho lingabi ngcono noma livele kaningi ngemuva kokuthatha i-zolmitriptan.
Uma uthatha i-zolmitriptan kaningi noma isikhathi eside kunesikhathi esinconyiwe, ikhanda lakho lingahle libe libi kakhulu noma lingavela kaningi. Akufanele uthathe i-zolmitriptan noma yimuphi omunye umuthi wekhanda izinsuku ezingaphezu kwezingu-10 ngenyanga. Shayela udokotela wakho uma udinga ukuthatha i-zolmitriptan ukwelapha amakhanda angaphezu kwamathathu esikhathini esiyinyanga engu-1.
Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.
Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.
Ngaphambi kokuthatha i-zolmitriptan,
- Tshela udokotela kanye nosokhemisi wakho uma uxabana ne-zolmitriptan, noma imiphi eminye imithi, noma iziphi izithako ezikumathebulethi e-zolmitriptan noma amaphilisi ahlukaniswa ngomlomo. Buza usokhemisi wakho ukuthola uhlu lwezithako.
- ungathathi i-zolmitriptan uma uphuze noma imuphi umuthi olandelayo emahoreni angama-24 adlule: amanye ama-agonists e-serotonin receptor akhethiwe afana ne-almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt) , noma i-sumatriptan (Imitrex, eTreximet); noma imithi yohlobo lwe-ergot efana ne-bromocriptine (Parlodel), i-cabergoline, i-dihydroergotamine (i-DHE 45, i-Migranal), i-ergoloid mesylates (i-Hydergine), i-ergonovine (i-Ergotrate), i-ergotamine (iCafergot, i-Ergomar, i-Wigraine), i-methylergonovine (iMethergine) ), kanye negolide (Permax).
- ungathathi i-zolmitriptan uma uthatha i-monoamine oxidase A (MAO-A) inhibitor efana ne-isocarboxazid (Marplan), phenelzine (Parnate), noma i-tranylcypromine (i-Nardil) noma uma uthathe omunye wale mithi emasontweni amabili edlule.
- Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, noma imikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: i-acetaminophen (iTylenol); imishanguzo efana ne-amitriptyline (Elavil), i-amoxapine (i-Asendin), i-clomipramine (i-Anafranil), i-desipramine (i-Norpramin), i-doxepin (i-Adapin, i-Sinequan), i-imipramine (i-Tofranil), i-nortriptyline (i-Aventyl, i-Pamelor), i-protripiline Surmontil); i-aspirin neminye imishanguzo yokulwa nokuvuvukala (ama-NSAID) njenge-ibuprofen (Advil, Motrin) ne-naproxen (Aleve, Naprosyn); i-cimetidine (Tagamet); izinto zokuvimbela inzalo ngomlomo (’amaphilisi okulawula inzalo); i-propranolol (Inderal); i-serotonin reuptake inhibitors (SSRIs) ekhethiwe njenge-citalopram (Celexa), i-escitalopram (Lexapro), i-fluoxetine (i-Prozac, i-Sarafem, e-Symbyax), i-fluvoxamine (i-Luvox), i-paroxetine (i-Paxil), ne-sertraline (i-Zoloft); ne-serotonin / norepinephrine reuptake inhibitors ekhethiwe (SNRIs) efana ne-desvenlafaxine (Pristiq), i-duloxetine (i-Cymbalta), i-sibutramine (i-Meridia), ne-venlafaxine (i-Effexor). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
- utshele udokotela wakho uma uke waba nesifo senhliziyo noma wake waba naso; isifo senhliziyo; i-angina (ubuhlungu besifuba); ukushaya kwenhliziyo okungajwayelekile; unhlangothi noma 'mini-stroke'; noma izinkinga zokujikeleza ezifana nemithambo ye-varicose, amahlule egazini emilenzeni, isifo sikaRaynaud (izinkinga zokugeleza kwegazi ukuya eminweni, ezinzwaneni, ezindlebeni nasekhaleni), noma isifo sesisu (isifo sohudo esinegazi nobuhlungu besisu obubangelwa ukwehla kokugeleza kwegazi kuye amathumbu). Udokotela wakho angakutshela ukuthi ungathathi i-zolmitriptan.
- utshele udokotela wakho uma ubhema noma ukhuluphele ngokweqile; uma uke waba nomfutho wegazi ophakeme noma owake waba nawo, i-cholesterol ephezulu, isifo sikashukela, noma isibindi noma isifo sezinso; uma usudlulile esikhathini (ukuguqula impilo); noma uma kukhona amalungu omndeni anesifo senhliziyo noma sohlangothi.
- tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma uhlela ukwenza ucansi ngenkathi uthatha lo muthi, khuluma nodokotela wakho ngezindlela ezisebenzayo zokulawula ukubeletha. Uma ukhulelwa ngenkathi uthatha i-zolmitriptan, shayela udokotela wakho.
- kufanele wazi ukuthi lo muthi ungakwenza ukozele noma ube nesiyezi. Ungashayeli imoto noma usebenzise imishini uze wazi ukuthi i-zolmitriptan ikuthinta kanjani.
- khuluma nodokotela wakho ngezimpawu zakho zekhanda ukuze uqiniseke ukuthi zibangelwa yi-migraine. I-Zolmitriptan akufanele isetshenziselwe ukwelapha izinhlobo ezithile zekhanda le-migraine (i-hemiplegic noma i-basilar) noma ezinye izinhlobo zekhanda (njengama-cluster headaches).
- uma une-phenylketonuria (i-PKU, isimo esizuzwe njengefa lapho kufanele kulandelwe ukudla okukhethekile ukuvimbela ukubola kwengqondo), kufanele wazi ukuthi amaphilisi ahlukaniswa ngomlomo aqukethe i-aspartame eyakha i-phenylalanine.
Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.
I-Zolmitriptan ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
- ukuzizwa ufudumele noma ubanda
- ukozela
- umlomo owomile
- isicanucanu
- isilungulela
- ukujuluka
- isiyezi noma ukuquleka
Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
- ubuhlungu, ukuqina, ingcindezi, noma isisindo esifubeni, emphinjeni, entanyeni noma emhlathini
- inkulumo ehamba kancane noma enzima
- ubuthakathaka noma ukuba ndikindiki kwengalo noma komlenze
- ukushesha, ukushaya ngamandla, noma ukushaya kwenhliziyo okungajwayelekile
- uhudo olunegazi
- ubuhlungu besisu obungazelelwe noma obukhulu
- ukuphaphatheka noma umbala oluhlaza okwesibhakabhaka weminwe nezinzwane
- ukuphelelwa umoya
- ukuvuvukala kwamehlo, ubuso, izindebe, ulimi, noma umphimbo
- ukuphefumula kanzima noma ukugwinya
- ukushaqeka
- ukuqubuka
- isifuba
- ubuhlungu, ukushisa, noma ukuncinza ezandleni noma ezinyaweni
Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).
Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Yigcine ekamelweni lokushisa kude nokukhanya, ukushisa okweqile, nomswakama (hhayi endlini yangasese). Lahla noma imaphi amaphilisi ahlukaniswa ngomlomo owasuse ephaketheni le-blister kodwa awasebenzisanga ngokushesha.
Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.
Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org
Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.
Izimpawu zokudlula ngokweqile zingafaka:
- ukozela ngokweqile
Gcina wonke ama-aphoyintimenti nodokotela wakho. Umfutho wegazi lakho kufanele uhlolwe njalo.
Kufanele ugcine idayari yekhanda ngokubhala phansi lapho uphathwa yikhanda nalapho uthatha i-zolmitriptan.
Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.
Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.
- Zomig®
- I-Zomig-ZMT®