Inaliti yeFoscarnet

-Delile

• Ngaphambi kokusebenzisa umjovo we-foscarnet,
• I-Foscarnet ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SEXWAYISO, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

I-Foscarnet ingadala izinkinga ezinkulu zezinso. Ingozi yokulimala kwezinso inkulu kubantu abaphelelwe amanzi emzimbeni. Udokotela wakho uzo-oda ukuhlolwa kwelabhorethri ngaphambi nangesikhathi sokwelashwa kwakho ukubona ukuthi izinso zakho ziyathinteka yini yile mithi. Tshela udokotela wakho uma uke waba nesifo sezinso noma unomlomo owomile, umchamo omnyama, ukwehla kokujuluka, isikhumba esomile, nezinye izimpawu zokoma noma osanda kuba nohudo, ukuhlanza, imfiva, ukutheleleka, ukujuluka okweqile, noma behlulekile ukuphuza uketshezi olwanele. Tshela udokotela kanye nosokhemisi wakho uma uthatha i-acyclovir (Zovirax); ama-antibiotic e-aminoglycoside afana ne-amikacin, kanamycin, neomycin, paromomycin, streptomycin, ne-tobramycin; i-amphotericin (i-Abelcet, i-Ambisome); i-cyclosporine (Gengraf, Neoral, Sandimmune); i-methotrexate (i-Otrexup, i-Rasuvo, i-Trexall); i-pentamidine (i-Nebupent, i-Pentam), noma i-tacrolimus (i-Astagraf, i-Prograf). Udokotela wakho angahle angafuni ukuthi uthole umjovo we-foscarnet. Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: ukuncipha kokuchama; ukuvuvukala kobuso, izingalo, izandla, izinyawo, amaqakala, noma imilenze engezansi; ukukhathala okungavamile; noma ubuthakathaka.

I-Foscarnet ingadala ukuquleka. Tshela udokotela wakho uma uke waquleka noma uke waquleka, ezinye izinkinga zesistimu yezinzwa, noma uma uke waba nezinga eliphansi le-calcium egazini lakho. Udokotela wakho mhlawumbe uzohlola izinga le-calcium egazini lakho ngaphambi kokuthola umjovo we-foscarnet nangesikhathi sokwelashwa. Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: ukuquleka; ukuba ndikindiki noma ukuncinza emlonyeni noma eminweni noma ezinzwaneni; ukushesha, ukushaya ngamandla, noma ukushaya kwenhliziyo okungajwayelekile; noma ukuqhuma kwemisipha.

Gcina wonke ama-aphoyintimenti nodokotela wakho, kufaka phakathi udokotela wamehlo, kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile, kufaka phakathi ukuhlolwa kwamehlo ngezikhathi ezithile, ngaphambi nangesikhathi sokwelashwa kwakho ukuze uhlole impendulo yomzimba wakho ku-foscarnet. Udokotela wakho angaphinde ahlele i-electrocardiogram (ECG; ukuhlolwa okulinganisa umsebenzi kagesi enhliziyweni) ngaphambi nangesikhathi sokwelashwa kwakho.

Umjovo we-Foscarnet usetshenziswa wedwa noma nge-ganciclovir (i-Cytovene) ukwelapha i-cytomegalovirus (CMV) retinitis (ukutheleleka kwamehlo okungadala ubumpumputhe) kubantu abanokutheleleka ngegciwane lesandulela ngculaza (i-HIV). Umjovo we-Foscarnet ubuye usetshenziselwe ukwelapha ukutheleleka kwe-herpes simplex virus (HSV) kwesikhumba kanye nolwelwesi lwamafinyila (umlomo, ingquza) kubantu amasosha omzimba wabo angasebenzi ngokujwayelekile nalapho ukwelashwa nge-acyclovir kungazange kusize. UFoscarnet usesigabeni semithi ebizwa ngama-antivirals. Isebenza ngokunciphisa ukukhula kwe-CMV ne-HSV. I-Foscarnet ilawula ukutheleleka kwe-CMV retinitis kanye ne-HSV esikhunjeni nasezikhungweni ze-mucus kepha ayizelaphi lezi zifo.

Umjovo weFoscarnet uza njengoketshezi oluzofakwa ngaphakathi (emthanjeni). Imvamisa ifakwa kancane ngaphezulu kwehora eli-1 kuye kwele-2 njalo ngamahora ayi-8 noma ayi-12. Ubude bokwelashwa kwakho buya ngokuthi uphendula kanjani emithini.

Ungathola umjovo we-foscarnet esibhedlela noma ungahlinzeka ngemithi ekhaya. Uma uzothola umjovo we-foscarnet ekhaya, umhlinzeki wakho wezokunakekelwa kwezempilo uzokukhombisa ukuthi uwusebenzisa kanjani umuthi. Qiniseka ukuthi uyaziqonda lezi zinkomba, bese ubuza umhlinzeki wakho wezokunakekelwa kwezempilo uma unemibuzo

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Umjovo we-Foscarnet kwesinye isikhathi usetshenziselwa ukwelapha nokuvimbela ukutheleleka kwe-CMV ezigulini ezinegciwane lesandulela ngculazi (i-HIV). Khuluma nodokotela wakho ngezingozi zokusebenzisa lo muthi ngesimo sakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokusebenzisa umjovo we-foscarnet,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-foscarnet, noma imiphi eminye imithi, noma iziphi izithako zomjovo we-foscarnet. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi uyayisho imishanguzo ebhalwe esigabeni ESIBALULEKILE SESEXWAYISO nakokulandelayo: amiodarone (Cordarone, Nexterone, Pacerone); i-azithromycin (iZithromax); i-clarithromycin (i-Biaxin); isisu (‘amaphilisi amanzi’) njenge-bumetanide, i-ethacrynic acid (i-Edecrin), i-furosemide (i-Lasix), noma i-torsemide (i-Demadex); i-dofetilide (Tikosyn); i-erythromycin (E-mycin, Ery-Tab, abanye); ama-antibiotic e-fluoroquinolone afaka i-ciprofloxacin (Cipro), i-gatifloxacin (i-Tequin), i-levofloxacin (i-Levaquin), i-moxifloxacin (i-Avelox), ne-ofloxacin (i-Floxin); imithi yokugula kwengqondo noma isicanucanu; procainamide; i-quinidine (ku-Nuedexta); i-ritonavir (iNorvir, eKaletra); i-saquinavir (i-Invirase); i-sotalol (iBetapace, iSorine); kanye ne-tricyclic antidepressants (’mood elevators’) njenge-amitriptyline, desipramine (Norpramin), doxepin (Silenor), noma i-nortriptyline (Pamelor). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo eminingi ingaxhumana nomjovo we-foscarnet, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu.
• utshele udokotela wakho uma ngabe uke waba ne-QT prolongation (isigqi senhliziyo esingajwayelekile esingaholela ekuphelelweni amandla, ekulahlekelweni ukwazi, ekuqulekeni, noma ekufeni okungazelelwe); amazinga aphansi we-potassium noma i-magnesium egazini lakho; Isifo senhliziyo; noma uma udla ukudla kasawoti okuphansi.
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthola umjovo we-foscarnet, shayela udokotela wakho.
• kufanele wazi ukuthi i-foscarnet ingakwenza ukozele noma ube nesiyezi. Ungashayeli imoto noma usebenzise imishini uze wazi ukuthi lo muthi ukuthinta kanjani.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

I-Foscarnet ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ukulunywa, ububomvu, ubuhlungu, noma ukuvuvukala endaweni lapho uthole khona umjovo wakho
• isicanucanu
• ubuhlungu besisu
• ukuhlungu obusemhlane
• ukulahlekelwa isifiso sokudla noma isisindo
• ukuqunjelwa
• ikhanda
• umbono uyashintsha
• ububomvu, ukucasuka, noma izilonda epeni
• ububomvu, ukucasuka, noma izilonda ezungeze isitho sangasese sowesifazane

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SEXWAYISO, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukuqubuka
• isifuba
• ukuvuvukala kwamehlo, ubuso, izindebe, ulimi, noma umphimbo
• ukuphefumula kanzima noma ukugwinya
• ubuhlungu besifuba
• ukushesha, ukushaya ngamandla, noma ukushaya kwenhliziyo okungajwayelekile
• ukuquleka
• ubumhlophe
• ukulahlekelwa ukwazi
• ukuhlanza
• isifo sohudo
• umkhuhlane, ukubanda, ukukhwehlela, noma ezinye izimpawu zokutheleleka
• ukopha okungajwayelekile noma ukulinyazwa
• indle emnyama neyokulinda
• ukuhlanza okunegazi noma okokuhlanza okubukeka njengezizathu zekhofi
• isikhumba esiphaphathekile
• ukuphelelwa umoya
• ukudideka
• ubuhlungu bemisipha noma amajaqamba
• ukujuluka okwandayo

I-Foscarnet ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi usebenzisa lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• isithuthwane
• ukuba ndikindiki noma ukuncinza emlonyeni noma eminweni noma ezinzwaneni
• ukuncipha kokuchama
• ukuvuvukala kobuso, izingalo, izandla, izinyawo, amaqakala noma imilenze engezansi
• ukukhathala okungajwayelekile noma ubuthakathaka

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Foscavir^®