I-Eplerenone

-Delile

• Ngaphambi kokuthatha i-eplerenone,
• I-Eplerenone ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Izimpawu ezilandelayo azivamile, kepha uma uhlangabezana nenye yazo, shayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka:

I-Eplerenone isetshenziswa yodwa noma ihlanganiswe neminye imithi yokwelapha umfutho wegazi ophezulu. I-Eplerenone isekilasini lemithi ebizwa ngabaphikisi be-mineralocorticoid receptor. Isebenza ngokuvimba isenzo se-aldosterone, into yemvelo emzimbeni enyusa umfutho wegazi.

Umfutho wegazi ophezulu yisimo esivamile futhi uma ungelashwa, ungadala umonakalo ebuchosheni, enhliziyweni, emithanjeni yegazi, ezinso nakwezinye izingxenye zomzimba. Ukulimala kwalezi zitho kungadala isifo senhliziyo, isifo senhliziyo, ukwehluleka kwenhliziyo, isifo sohlangothi, ukwehluleka kwezinso, ukungaboni, nezinye izinkinga. Ngaphezu kokuthatha umuthi, ukwenza ushintsho endleleni ophila ngayo kuzosiza nasekulawuleni umfutho wegazi. Lezi zinguquko zifaka phakathi ukudla ukudla okunamafutha nosawoti omncane, ukugcina isisindo esinempilo, ukuzivocavoca okungenani imizuzu engama-30 izinsuku eziningi, ukungabhemi, nokusebenzisa utshwala ngokulinganisela.

I-Eplerenone iza njengethebhulethi ezothathwa ngomlomo. Imvamisa iphuzwa kanye noma kabili ngosuku, noma ngaphandle kokudla. Ukukusiza ukuthi ukhumbule ukuthatha i-eplerenone, yithathe ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-eplerenone njengoba iqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Udokotela wakho angakuqala ngomthamo ophansi we-eplerenone futhi akhuphule umthamo wakho ngemuva kwamasonto amane.

I-Eplerenone ilawula umfutho wegazi ophakeme kodwa ayiyelaphi. Kungathatha amasonto ama-4 noma ngaphezulu ngaphambi kokuthi uzwe inzuzo ephelele ye-eplerenone. Qhubeka uthathe i-eplerenone noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-eplerenone ngaphandle kokukhuluma nodokotela wakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-eplerenone,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-eplerenone, noma imiphi eminye imithi, noma yiziphi izithako ezibhebheni ze-eplerenone. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• ungathathi i-eplerenone uma uthatha i-amiloride (Midamor), i-amiloride ne-hydrochlorothiazide, i-itraconazole (i-Onmel, i-Sporanox), i-ketoconazole (i-Nizoral), izithako ze-potassium, i-spironolactone (i-Aldactone), i-spironolactone ne-hydrochlorothiazide (i-Aldactazide), i-Aldactazide, i-Aldactazide) i-triamterene ne-hydrochlorothiazide (iDyazide, iMaxzide).
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokunganikezwa imishanguzo, amavithamini, nezithako zokudla okunomsoco okwenzayo. Qiniseka ukuthi usho noma yikuphi kokulandelayo: i-angiotensin converting enzyme (ACE) inhibitors efana ne-benazepril (Lotensin, eLotrel), i-captopril (i-Capoten), i-enalapril (i-Vasotec, ngesi-Vaseretic), i-fosinopril, i-lisinopril (e-Prinzide, e-Zestoretic), ne-quinapril (i-Accupril, nge-Accuretic, ngesiQuinaretic); ama-angiotensin II receptor antagonists afana ne-azilsartan (Edarbi, e-Edarbyclor), candesartan (Atacand, e-Atacand HCT), eprosartan (Teveten), irbesartan (Avapro, e-Avalide), losartan (Cozaar, e-Hyzaar), olmesartan (Benicar, Azzor , eBenicar HCT), telmisartan (Micardis, eMicardis HCT, eTwynsta), nase-valsartan (Diovan, eDiovan HCT, Exforge); i-aspirin nezinye izidakamizwa ezingezona ukuvuvukala (ama-NSAID) njenge-ibuprofen (Advil, Motrin) ne-naproxen (Aleve, Naprosyn); i-cimetidine (Tagamet); i-clarithromycin (i-Biaxin); i-danazol; i-delavirdine (i-Rescriptor); i-diltiazem (Cardizem, Dilacor, Tiazac, abanye); i-erythromycin (E.E.S., E-Mycin, Erythrocin); i-fluconazole (iDiflucan); i-fluoxetine (i-Prozac, iSarafem, i-Selfemra); i-fluvoxamine (i-Luvox); I-HIV protease inhibitors efana ne-indinavir (Crixivan), i-ritonavir (i-Norvir, e-Kaletra), ne-saquinavir (i-Invirase); i-isoniazid (iLaniazid, eRifamate, Rifater); i-lithium (i-Lithobid); i-metronidazole (i-Flagyl); nefazodone; i-verapamil (Calan, Covera, Verelan, eTarka); futhi zafirlukast (Accolate). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• utshele udokotela wakho ukuthi uthatha miphi imikhiqizo yamakhambi, ikakhulukazi iSt John's wort.
• Tshela udokotela wakho uma ngabe uke waba namazinga aphezulu egazi e-potassium, isifo sikashukela, i-gout, noma isibindi noma isifo sezinso.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha i-eplerenone, shayela udokotela wakho.

Khuluma nodokotela wakho ngokuphuza ijusi lamagilebhisi ngenkathi uthatha lo muthi.

Ungasebenzisi okokufaka usawoti okuqukethe i-potassium ngenkathi uthatha i-eplerenone. Uma udokotela wakho ekutshela ukuthi udle usawoti ophansi noma ukudla okune-sodium eningi, landela lezi zinkomba ngokucophelela.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Eplerenone ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ikhanda
• isiyezi
• isifo sohudo
• ubuhlungu besisu
• ukukhwehlela
• ukukhathala ngokweqile
• izimpawu ezinjengomkhuhlane
• ukukhulisa amabele noma isisa
• ukopha okungavamile kwesitho sangasese sowesifazane

Eminye imiphumela emibi ingaba mibi. Izimpawu ezilandelayo azivamile, kepha uma uhlangabezana nenye yazo, shayela udokotela wakho ngokushesha:

• ubuhlungu besifuba
• ukuluma ezingalweni nasemilenzeni
• ukulahleka kwethoni yemisipha
• ubuthakathaka noma ubunzima emilenzeni
• ukudideka
• ukungabi namandla
• isikhumba esibandayo, esimpunga
• ukushaya kwenhliziyo okungajwayelekile

I-Eplerenone ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka:

• ukuquleka
• isiyezi
• ukungaboni kahle
• isisu esibuhlungu
• ukuluma ezingalweni nasemilenzeni
• ukulahleka kwethoni yemisipha
• ubuthakathaka noma ubunzima emilenzeni
• ukudideka
• ukungabi namandla
• isikhumba esibandayo, esimpunga
• ukushaya kwenhliziyo okungajwayelekile noma okuhamba kancane

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzohlola umfutho wegazi njalo futhi a-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ku-eplerenone.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

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