Inaliti ye-Pramlintide

-Delile

• Ingozi ye-hypoglycemia ingaba nkulu ezimweni ezithile. Shayela udokotela wakho uma uhlela ukusebenza kakhulu kunokujwayelekile. Uma unemibandela elandelayo akufanele usebenzise i-pramlintide futhi kufanele ushayele udokotela wakho ukuthola ukuthi wenzeni:
• Ngaphambi kokusebenzisa umjovo we-pramlintide,
• I-Pramlintide ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Izimpawu zokudlula ngokweqile zingafaka:

Uzosebenzisa i-pramlintide nge-insulin yesikhathi sokudla ukulawula amazinga akho kashukela egazini. Uma usebenzisa i-insulin, kunethuba lokuthi uzozwa i-hypoglycemia (ushukela ophansi wegazi). Le ngozi ingase ibe nkulu phakathi namahora amathathu okuqala ngemuva kokujova i-pramlintide, ikakhulukazi uma unesifo sikashukela sohlobo 1 (isimo lapho umzimba ungakhiqizi i-insulin ngakho-ke awukwazi ukulawula inani likashukela egazini). Ungazilimaza wena noma abanye uma ushukela wegazi lakho wehla ngenkathi ubandakanyeka emsebenzini odinga ukuthi uqaphele noma ucabange kahle. Ungashayeli imoto noma usebenzise imishini esindayo uze wazi ukuthi i-pramlintide iluthinta kanjani ushukela wegazi lakho. Khuluma nodokotela wakho mayelana neminye imisebenzi okufanele uyigweme ngenkathi usebenzisa i-pramlintide.

Tshela udokotela wakho uma unesifo sikashukela isikhathi eside, uma unesifo sikashukela, uma ungakwazi ukusho ukuthi ushukela wegazi uphansi, uma udinga ukwelashwa kwe-hypoglycemia izikhathi eziningana ezinyangeni eziyisithupha ezedlule ,, noma uma une-gastroparesis (ukuhamba kancane kokudla kusuka esiswini kuya emathunjini amancane. Udokotela wakho mhlawumbe uzokutshela ukuthi ungasebenzisi i-pramlintide. Futhi utshele udokotela wakho uma uthatha noma imiphi yale mithi elandelayo: umfutho wegazi ophakeme, isifo senhliziyo, noma isifo sezinso sikashukela; ama-beta blockers anjenge-atenolol (e-Tenoretic), labetalol (Trandate), metoprolol (Lopressor, Toprol XL, eDutoprol, eLopressor HCT), nadolol (Corgard, eCorzide), kanye nepropranolol (Hemangeol, Inderal, Innopran, e-Inderide); clonidine (Catapres, Duraclon, Kapvay, in Clorpres); disopyramide (Norpace); fenofibrate (Antara, Lipofen, Tricor, others); fluoxetine (Prozac, Sarafem, Selfemra, in Symbyax); gemfibrozil (L i-opid); i-guanethidine (Ismelin; ayisatholakali e-U.S.); eminye imithi yesifo sikashukela; i-lanreotide (iSomatuline Depot); i-monoamine oxidase (MAO) inhibitors efana ne-isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), ne-tranylcypromine (i-Parnate); i-pentoxifylline (Pentoxil); i-propoxyphene (iDarvon; ayisatholakali e-U.S.); qamba kabusha; ubuhlungu be-salicylate buqeda njenge-aspirin; nama-antibiotic e-sulfonamide afana ne-trimethoprim / sulfamethoxazole (Bactrim, Septra).

Ngenkathi usebenzisa i-pramlintide, kufanele ulinganise ushukela wegazi ngaphambi nangemva kokudla ngakunye nesikhathi sokulala. Uzodinga futhi ukubona noma ukukhuluma nodokotela wakho kaningi, futhi uvame ukushintsha imithamo yakho ye-pramlintide ne-insulini ngokuyaleza izinkomba zikadokotela wakho. Tshela udokotela wakho uma ucabanga ukuthi kuzoba nzima ngawe ukwenza lezi zinto, uma uke waba nobunzima ekuhloleni ushukela wegazi lakho noma ukusebenzisa i-insulin yakho ngendlela efanele esikhathini esedlule, noma uma ukuthola kunzima ukuphatha imishanguzo yakho ngemuva kokuqala ukusebenzisa sbhabha.

Udokotela wakho uzokwehlisa umthamo wakho we-insulin lapho uqala ukusebenzisa i-pramlintide. Udokotela wakho uzokuqala ngomthamo ophansi we-pramlintide futhi uzokhulisa kancane kancane umthamo wakho. Shayela udokotela wakho ngokushesha uma unesicanucanu ngalesi sikhathi; umthamo wakho ungadinga ukuguqulwa noma kungadingeka ukuthi uyeke ukusebenzisa i-pramlintide. Udokotela wakho mhlawumbe uzoshintsha umthamo wakho we-insulin uma usebenzisa umthamo we-pramlintide olungele wena. Landela zonke lezi zinkomba ngokucophelela bese ubuza udokotela wakho noma usokhemisi ngokushesha uma ungaqiniseki ukuthi kufanele usebenzise i-insulin noma i-pramlintide engakanani.

Ingozi ye-hypoglycemia ingaba nkulu ezimweni ezithile. Shayela udokotela wakho uma uhlela ukusebenza kakhulu kunokujwayelekile. Uma unemibandela elandelayo akufanele usebenzise i-pramlintide futhi kufanele ushayele udokotela wakho ukuthola ukuthi wenzeni:

• uhlela ukweqa ukudla.
• uhlela ukudla isidlo esinama-calories angaphansi kwama-250 noma ama-gramu angama-30 ama-carbohydrate.
• awukwazi ukudla ngoba uyagula.
• awukwazi ukudla ngoba uhlelelwe ukuhlinzwa noma ukuhlolwa kokwelapha.
• ushukela wegazi lakho uphansi kakhulu ngaphambi kokudla.

Utshwala bungadala ukwehla kukashukela egazini. Buza udokotela wakho mayelana nokusetshenziswa okuphephile kweziphuzo ezidakayo ngenkathi usebenzisa i-pramlintide.

Shayela udokotela wakho ngokushesha uma ushukela wegazi lakho uphansi kunokujwayelekile noma uma unezinye zezimpawu ezilandelayo zeshukela eliphansi egazini: indlala, ikhanda elibuhlungu, ukujuluka, ukuqhaqhazela ingxenye yomzimba wakho ongeke ukwazi ukuyilawula, ukucasuka, ubunzima bokugxila, ukulahlekelwa ukwazi, ukuquleka, noma ukuquleka. Qiniseka ukuthi uhlala unomthombo osebenzayo osheshayo njengoshukela onzima, ujusi, amaphilisi e-glucose, noma i-glucagon etholakalayo yokwelapha i-hypoglycemia.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa nge-pramlintide futhi isikhathi ngasinye lapho ugcwalisa umuthi wakho. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungathola futhi iMihlahlandlela Yezokwelapha kwiwebhusayithi ye-FDA: http://www.fda.gov.

I-Pramlintide isetshenziswa nesikhathi sokudla i-insulin ukulawula amazinga kashukela egazini kubantu abanesifo sikashukela. I-Pramlintide isetshenziswa kuphela ekwelapheni iziguli ezinoshukela wegazi obungeke ulawulwe yi-insulin noma i-insulin kanye nemithi yomlomo yesifo sikashukela. I-Pramlintide isekilasini lemithi ebizwa ngama-antihyperglycemics. Isebenza ngokunciphisa ukuhamba kokudla esiswini. Lokhu kuvimbela ushukela wegazi ekukhuphukeni kakhulu ngemuva kokudla, futhi kunganciphisa ukudla futhi kubangele ukwehla kwesisindo.

Ngokuhamba kwesikhathi, abantu abanesifo sikashukela kanye noshukela ophakeme wegazi bangakhula babe nezinkinga ezinkulu noma ezisongela impilo, kufaka phakathi isifo senhliziyo, isifo sohlangothi, izinkinga zezinso, ukulimala kwemizwa nezinkinga zamehlo. Ukusebenzisa imithi, ukwenza izinguquko endleleni ophila ngayo (isb., Ukudla, ukuzivocavoca, ukuyeka ukubhema), nokuhlola njalo ushukela wegazi lakho kungasiza ukuphatha isifo sikashukela futhi kuthuthukise impilo yakho. Lokhu kwelashwa kunganciphisa namathuba akho okuhlaselwa yisifo senhliziyo, isifo sohlangothi, noma ezinye izinkinga ezihlobene nesifo sikashukela njengokuhluleka kwezinso, ukulimala kwemizwa (okundikindiki, imilenze ebandayo noma izinyawo; ukwehla kwekhono lezocansi kwabesilisa nabesifazane), izinkinga zamehlo, kufaka phakathi izinguquko noma ukulahleka kombono, noma isifo sezinsini. Udokotela wakho nabanye abahlinzeki bezokunakekelwa kwezempilo bazokhuluma nawe ngendlela engcono yokuphatha isifo sikashukela.

I-Pramlintide iza njengesisombululo (uketshezi) epeni lokufaka elifakiwe ukuze ujove ngaphansi (ngaphansi kwesikhumba). Imvamisa ijovwa kaningana ngosuku, ngaphambi kokudla ngakunye okubandakanya okungenani ama-calories angama-250 noma ama-gramu angama-30 we-carbohydrate. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Sebenzisa i-pramlintide njengoba nje kuqondisiwe. Ungayisebenzisi ngaphezulu noma ngaphansi kwayo noma uyisebenzise kaningi kunokuyalelwa ngudokotela wakho.

I-Pramlintide ilawula isifo sikashukela kepha ayiselaphi. Qhubeka nokusebenzisa i-pramlintide noma ngabe uzizwa uphilile. Ungayeki ukusebenzisa i-pramlintide ngaphandle kokukhuluma nodokotela wakho. Uma uyeka ukusebenzisa i-pramlintide nganoma yisiphi isizathu, ungaqali ukuyisebenzisa futhi ngaphandle kokukhuluma nodokotela wakho.

Qiniseka ukuthi uyazi ukuthi yikuphi okunye okuhlinzekwayo, njengezinaliti, okudingayo ukujova umuthi wakho. Buza udokotela wakho noma usokhemisi ukuthi iziphi izinhlobo zezinaliti ozodinga ukujova umuthi wakho. Funda ngokucophelela futhi uqonde imiyalo yomkhiqizi yokujova i-pramlintide usebenzisa ipeni. Futhi qiniseka ukuthi uyazi ukuthi ungasetha kanjani ipeni elisha futhi nini. Cela udokotela wakho noma usokhemisi ukuthi akubonise ukuthi uyisebenzisa kanjani ipeni. Landela izinkomba ngokucophelela. Ungaxubi i-pramlintide ne-insulin.

Hlala ubheka isisombululo sakho sepeni le-pramlintide ngaphambi kokusijova. Kufanele icace futhi ingenambala. Ungasebenzisi i-pramlintide uma inombala, inamafu, ijiyile, iqukethe izinhlayiya eziqinile, noma uma usuku lokuphelelwa isikhathi kwelebula lephakeji seludlulile.

Ungalokothi usebenzise izinaliti futhi ungalokothi wabelane ngezinaliti noma izibaya. Susa njalo inaliti ngemuva nje kokujova umthamo wakho. Lahla izinaliti esitsheni esingamelana nokubhoboza. Buza udokotela wakho noma usokhemisi ukuthi ungasilahla kanjani isitsha esimelana nokubhoboza.

Ungajova i-pramlintide noma kuphi esiswini noma ethangeni. Ungafaki i-pramlintide engalweni yakho. Khetha indawo ehlukile yokujova i-pramlintide nsuku zonke. Qiniseka ukuthi indawo oyikhethayo ingaphezu kwamasentimitha ama-2 ukusuka lapho uzofaka khona i-insulin.

Kufanele ujove i-pramlintide ngaphansi kwesikhumba ngendlela efanayo nokujova i-insulin. Vumela ipeni le-pramlintide ukuthi lifudumale ekamelweni lokushisa ngaphambi kokujova umuthi. Uma unemibuzo mayelana nokujova i-pramlintide, buza udokotela wakho noma usokhemisi.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokusebenzisa umjovo we-pramlintide,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-pramlintide, noma imiphi eminye imithi, i-metacresol, noma ezinye izithako ezisepeni le-pramlintide. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela nemishanguzo ongayinikiwe, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyiphuzayo. Qiniseka ukuthi uyayisho imithi efakwe kuhlu esigabeni ESIBALULEKILE SESEXWAYISO nanoma yikuphi okulandelayo: i-acarbose (Precose); ama-antihistamine; i-atropine (Atropen, eLomotil, abanye); ama-anti-depressants (’mood elevators’) abizwa ngokuthi ama-tricyclic antidepressants; imishanguzo ethile yokwelapha i-asthma, uhudo, isifo samaphaphu, ukugula ngengqondo, ukugula okunyakazayo, isinye esisebenza ngokweqile, ubuhlungu, isifo sikaParkinson, isisu noma amajaqamba emathumbu, izilonda, nesisu esibuhlungu; laxatives; miglitol (Glyset); nezithambisi zendle. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• uma uthatha izinto zokuvimbela inzalo ngomlomo (amaphilisi okulawula ukubeletha), imishanguzo yezinhlungu, noma ama-antibiotic, yithathe okungenani ihora elilodwa ngaphambi noma ngemuva kwamahora amabili usebenzise i-pramlintide.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi usebenzisa i-pramlintide, shayela udokotela wakho.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi usebenzisa i-pramlintide.

Udokotela wakho, uthisha wokudla, noma uthisha wesifo sikashukela uzokusiza ukuthi wakhe uhlelo lokudla olukusebenzelayo. Landela uhlelo lokudla ngokucophelela.

Yeqa umthamo ophuthelwe bese usebenzisa umthamo wakho ojwayelekile we-pramlintide ngaphambi kokudla kwakho okulandelayo okukhulu. Ungasebenzisi umthamo ophindwe kabili ukwenza okulahlekile.

I-Pramlintide ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ububomvu, ukuvuvukala, ukulinyazwa, noma ukulunywa kusayithi lomjovo we-pramlintide
• ukulahlekelwa isifiso sokudla
• ubuhlungu besisu
• ukukhathala ngokweqile
• isiyezi
• ukukhwehlela
• Umphimbo obuhlungu
• ubuhlungu obuhlangene

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi izimpawu ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha.

I-Pramlintide ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi usebenzisa lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina izibaya ze-pramlintide ezingavulwa esiqandisini futhi uvikele ekukhanyeni; ungaziqandisi izibaya. Lahla noma yiziphi izibaya ezazifriziwe noma zivezwe ukushisa. Ungagcina izibaya ze-pramlintide ezivuliwe esiqandisini noma ekamelweni lokushisa, kepha kufanele uzisebenzise zingakapheli izinsuku ezingama-30. Lahla noma yiziphi izibaya ze-pramlintide ezivuliwe ngemuva kwezinsuku ezingama-30.

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka:

• isisu esibuhlungu
• ukuhlanza
• isifo sohudo
• isiyezi
• ukuqhuma

Ungavumeli omunye umuntu asebenzise imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• ISymlin Pen^®