Indomethacin

-Delile

• Ukuze usebenzise ama-suppositories e-indomethacin, landela lezi zinyathelo:
• Ngaphambi kokuthatha indomethacin,
• I-Indomethacin ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalezi zimpawu ezilandelayo noma lezo ezishiwo esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha. Ungaphinde uthathe i-indomethacin uze ukhulume nodokotela wakho.
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

Abantu abathatha izidakamizwa ezingezona ukuvuvukala (ama-NSAID) (ngaphandle kwama-aspirin) afana ne-indomethacin bangaba nengozi enkulu yokuhlaselwa yisifo senhliziyo noma isifo sohlangothi kunabantu abangayiphuzi le mithi. Le micimbi ingenzeka ngaphandle kwesixwayiso futhi ingadala ukufa. Le ngozi ingahle ibe phezulu kubantu abathatha ama-NSAID isikhathi eside. Ungathathi i-NSAID efana ne-indomethacin uma usanda kuhlaselwa yinhliziyo, ngaphandle uma uqondiswe ngudokotela wakho. Tshela udokotela wakho uma wena noma omunye emndenini wakho enesifo senhliziyo, ehlaselwa yisifo senhliziyo, noma sohlangothi, uma ubhema, nokuthi ngabe uke waba ne-cholesterol ephezulu, umfutho wegazi ophakeme noma isifo sikashukela. Thola usizo lwezokwelapha oluphuthumayo ngokushesha uma uhlangabezana nalezi zimpawu ezilandelayo: Ubuhlungu besifuba, ukuphefumula okuncane, ukuba buthakathaka engxenyeni eyodwa noma ohlangothini lomzimba, noma ukukhuluma okungaqinile.

Uma uzobe uhlolwa umthambo we-coronary bypass graft (CABG; uhlobo lokuhlinzwa kwenhliziyo), akufanele uthathe i-indomethacin ngaphambi noma ngemuva kokuhlinzwa.

Ama-NSAID afana ne-indomethacin angadala izilonda, ukuphuma kwegazi, noma izimbobo esiswini noma emathunjini. Lezi zinkinga zingakhula nganoma yisiphi isikhathi ngesikhathi sokwelashwa, zingenzeka ngaphandle kwezimpawu zokuxwayisa, futhi zingadala nokufa. Ingozi ingaba phezulu kubantu abathatha ama-NSAID isikhathi eside, sebekhulile ngeminyaka, benempilo ebuthaka, noma bephuza utshwala obuningi ngenkathi uthatha i-indomethacin. Tshela udokotela wakho uma uthatha noma imuphi wale mithi elandelayo: ama-anticoagulants (’ama-thinner egazi’) afana ne-warfarin (Coumadin, Jantoven); i-aspirin; amanye ama-NSAID afana ne-diflunisal (Dolobid), ibuprofen (Advil, Motrin) ne-naproxen (Aleve, Naprosyn); i-steroids yomlomo efana ne-dexamethasone, i-methylprednisolone (i-Medrol), ne-prednisone (i-Rayos); i-serotonin reuptake inhibitors (SSRIs) ekhethiwe njenge-citalopram (Celexa), i-fluoxetine (i-Prozac, i-Sarafem, i-Selfemra, ku-Symbyax), i-fluvoxamine (i-Luvox), i-paroxetine (i-Brisdelle, i-Paxil, i-Pexeva) ne-sertraline (i-Zoloft); noma i-serotonin norepinephrine reuptake inhibitors (SNRIs) efana ne-desvenlafaxine (Khedezla, Pristiq), duloxetine (Cymbalta), ne-venlafaxine (Effexor XR). Phinda utshele udokotela wakho uma uke waba nezilonda noma wopha esiswini noma emathunjini noma kwezinye izifo zokopha. Uma uhlangabezana nenye yalezi zimpawu ezilandelayo, yeka ukuthatha i-indomethacin bese ushayela udokotela wakho: ubuhlungu besisu, isilungulela, ukuhlanza okunegazi noma okubukeka njengezizathu zekhofi, igazi esitokisini, noma izitulo ezimnyama nezokulinda.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzoqapha izimpawu zakho ngokucophelela futhi mhlawumbe uzo-oda izivivinyo ezithile ukuze ahlole impendulo yomzimba wakho ku-indomethacin. Qiniseka ukuthi utshela udokotela wakho ukuthi uzizwa kanjani ukuze udokotela wakho akwazi ukukubeka inani elifanele lemithi yokwelapha isimo sakho ngengozi ephansi kakhulu yemiphumela emibi kakhulu.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa nge-indomethacin futhi isikhathi ngasinye lapho ugcwalisa umuthi wakho. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs) noma iwebhusayithi yomkhiqizi ukuthola uMhlahlandlela Wezokwelapha.

I-Indomethacin isetshenziselwa ukudambisa ubuhlungu obulinganiselayo kuya kabuhlungu, ubumnene, ukuvuvukala, nokuqina okubangelwa i-osteoarthritis (i-arthritis ebangelwa ukuwohloka kolwelwesi lwamajoyini), isifo samathambo (isifo samathambo esibangelwa ukuvuvukala kolwelwesi lwamajoyini), kanye ne-ankylosing i-spondylitis (i-arthritis ethinta kakhulu umgogodla). I-Indomethacin nayo isetshenziselwa ukwelapha ubuhlungu ehlombe obubangelwa yi-bursitis (ukuvuvukala kwesikhwama esigcwele uketshezi esihlangwini sehlombe) kanye ne-tendinitis (ukuvuvukala kwezicubu ezixhuma imisipha nethambo). Ama-capsule akhishwa ngokushesha e-Indomethacin, ukumiswa (uketshezi) kanye nama-suppositories nawo asetshenziselwa ukwelapha i-gouty arthritis (ukuhlaselwa kobuhlungu obukhulu bamalunga nokuvuvukala okubangelwa ukwakhiwa kwezinto ezithile emajoyintini). I-Indomethacin isekilasini lemithi ebizwa ngama-NSAID. Isebenza ngokumisa ukukhiqizwa komzimba wento ebangela ubuhlungu, umkhuhlane nokuvuvukala.

I-Indomethacin iza njenge-capsule, i-capsule enwetshiwe (esebenza isikhathi eside), nokumiswa okuzothathwa ngomlomo nanjenge-suppository ezosetshenziswa ngohlangothi. Ama-capsule e-Indomethacin noketshezi ngokuvamile kuthathwa izikhathi ezimbili kuya kwezine ngosuku. Ama-suppositories e-Indomethacin ngokuvamile asetshenziswa izikhathi ezimbili noma ezine nsuku zonke. Amaphilisi akhululiwe ngokuvamile athathwa kanye noma kabili ngosuku. Amaphilisi we-Indomethacin, ama-capsule akhishwe isikhathi eside, kanye nokumiswa kufanele kuthathwe nokudla, ngokushesha ngemuva kokudla, noma ngama-antacids. Thatha i-indomethacin ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-indomethacin njengoba iqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Gwinya wonke amaphilisi akhishwe isikhathi eside; ungawahlukanisi, ungawahlafune noma uwagxoze.

Nyakazisa ukumiswa kahle ngaphambi kokusebenzisa ngakunye ukuxuba umuthi ngokulinganayo.

Udokotela wakho angashintsha umthamo wemithi yakho ngesikhathi sokwelashwa kwakho. Kwezinye izimo, udokotela wakho angakuqala ngomthamo ophansi we-indomethacin futhi akhuphule kancane umthamo wakho, hhayi kaningi ngesonto. Kwezinye izimo, udokotela wakho angakuqala ngomthamo omaphakathi we-indomethacin futhi wehlise umthamo wakho uma izimpawu zakho sezilawuliwe. Landela lezi zinkomba ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo.

Ukuze usebenzise ama-suppositories e-indomethacin, landela lezi zinyathelo:

1. Susa ukugoqwa.
2. Gcoba ichopho le-suppository emanzini.
3. Lala ngohlangothi lwakho lwesobunxele bese uphakamisa idolo lakho langakwesokudla esifubeni sakho. (Umuntu ongakwesobunxele kufanele alale ohlangothini lwesokunene aphakamise idolo langakwesokunxele.)
4. Usebenzisa umunwe wakho, faka i-suppository cishe nge-intshi eyodwa (2.5 amasentimitha) ku-rectum. Yibambe endaweni okomzuzwana.
5. Sukuma ngemuva kwemizuzu eyi-15. Geza izandla zakho kahle bese uqala imisebenzi yakho ejwayelekile.
6. Kufanele uzame ukugcina i-suppository isendaweni futhi ugweme ukuhamba kwamathumbu ihora eli-1 ngemuva kokufaka i-suppository.

I-Indomethacin kwesinye isikhathi isetshenziselwa ukudambisa umkhuhlane, ubuhlungu, nokuvuvukala okubangelwa izinhlobo eziningi zezimo noma ukulimala, ukunciphisa inani le-calcium egazini, nokwelapha uhlobo oluthile lomfutho wegazi ophansi. Khuluma nodokotela wakho ngezingozi zokusebenzisa lo muthi ngesimo sakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha indomethacin,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-indomethacin, i-aspirin noma amanye ama-NSAID afana ne-ibuprofen (Advil, Motrin) kanye ne-naproxen (i-Aleve, iNaprosyn), noma imuphi omunye umuthi, noma iziphi izithako ezingasebenzi kuma-capsule e-indomethacin, ukumiswa, ukukhululwa okwandisiwe ama-capsule, noma ama-suppositories. Buza usokhemisi wakho ukuthola uhlu lwezithako ezingasebenzi.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi uyayisho imishanguzo ebhalwe esigabeni ESIBALULEKILE SESEXWAYISO nakokulandelayo: ama-enzyme aguqula i-angiotensin (ACE) anjenge-benazepril (Lotensin, eLotrel), i-captopril, i-enalapril (i-Vasotec, e-Vaseretic), i-fosinopril, i-lisinopril ( ngesiZestoretic), moexipril (Univasc, in Uniretic), perindopril (Aceon, in Prestalia), quinapril (Accupril, in Accuretic, in Quinaretic), ramipril (Altace), kanye netrandolapril (Mavik, eTarka); ama-angiotensin receptor blockers anjenge-candesartan (Atacand, e-Atacand HCT), eprosartan (Teveten), irbesartan (Avapro, e-Avalide), losartan (Cozaar. e-Hyzaar), olmesartan (Benicar, e-Azor, e-Benicar HCT, e-Tribenzor), i-telmisartan (Micardis, eMicardis HCT, eTwynsta), ne-valsartan (eDiovan HCT, e-Exforge); ama-beta blocker anjenge-atenolol (Tenormin, in Tenoretic), labetalol (Trandate), metoprolol (Lopressor, Toprol XL, eDutoprol), nadolol (Corgard, eCorzide), kanye nepropranolol (Hemangeol, Inderal, Innopran); i-cyclosporine (Gengraf, Neoral, Sandimmune); i-digoxin (i-Lanoxin); i-diuretics (‘amaphilisi amanzi’) afana ne-triamterene (Dyrenium, eDyazide); i-lithium (i-Lithobid); i-methotrexate (i-Otrexup, i-Rasuvo, i-Trexall); i-phenytoin (iDilantin, Phenytek); kanye ne-probenecid (i-Probalan, ku-Col-Probenecid). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• Tshela udokotela wakho uma uke waba nesifuba somoya noma wake waba naso, ikakhulukazi uma unezimpumputhe noma izimpumputhe ezivuthayo njalo (ukuvuvukala kolwelwesi lwekhala); ukwehluleka kwenhliziyo; ukuquleka; Isifo sikaParkinson; ukudana noma ukugula kwengqondo; noma isifo sesibindi noma sezinso. Uma uzosebenzisa ama-indomethacin suppositories, futhi utshele udokotela wakho uma ngabe uke waba ne-proctitis (ukuvuvukala kwe-rectum) noma uke waba negazi ngemuva.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa; noma ukuncelisa ibele. I-Indomethacin ingalimaza umbungu futhi idale izinkinga ngokulethwa uma ithathwa cishe amasonto angama-20 noma kamuva ngesikhathi sokukhulelwa. Ungathathi i-indomethacin ezungeze noma ngemuva kwamasonto angama-20 ukhulelwe, ngaphandle kwalapho utshelwa ngudokotela wakho ukuthi wenze njalo. Uma ukhulelwa ngenkathi uthatha i-indomethacin, shayela udokotela wakho.
• khuluma nodokotela wakho ngezingozi nezinzuzo zokuthatha i-indomethacin uma uneminyaka engama-65 noma ngaphezulu. Abantu abadala asebekhulile akufanele bavame ukuthatha i-indomethacin ngoba ayiphephile njengeminye imithi engasetshenziswa ukwelapha isimo esifanayo.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi uthatha i-indomethacin.
• kufanele wazi ukuthi lo muthi ungakwenza ukozele. Ungashayeli imoto noma usebenzise imishini uze wazi ukuthi lo muthi ukuthinta kanjani.
• khuluma nodokotela wakho ngokusetshenziswa okuphephile kotshwala ngenkathi welashwa nge-indomethacin. Utshwala bungenza imiphumela emibi ye-indomethacin ibe yimbi kakhulu.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Indomethacin ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ikhanda
• isiyezi
• ukuhlanza
• isifo sohudo
• ukuqunjelwa
• ukucasuka kwe-rectum
• umuzwa oqhubekayo wesidingo sokukhipha amathumbu
• kukhala ezindlebeni

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalezi zimpawu ezilandelayo noma lezo ezishiwo esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha. Ungaphinde uthathe i-indomethacin uze ukhulume nodokotela wakho.

• ukuzuza kwesisindo okungaqondakali
• ukuphefumula okuncane noma ukuphefumula kanzima
• ukuvuvukala esiswini, emaqakaleni, ezinyaweni, noma emilenzeni
• imfiva
• amabhamuza
• ukuqubuka
• ukulunywa
• isifuba
• ukuvuvukala kwamehlo, ubuso, ulimi, izindebe, umphimbo, noma izandla
• ukuphefumula kanzima noma ukugwinya
• ukushaqeka
• isikhumba esiphaphathekile
• ukushaya kwenhliziyo okusheshayo
• ukukhathala ngokweqile
• ukopha okungajwayelekile noma ukulinyazwa
• ukungabi namandla
• isicanucanu
• ukulahlekelwa isifiso sokudla
• ubuhlungu engxenyeni engenhla kwesokudla yesisu
• izimpawu ezinjengomkhuhlane
• ukuphuzi kwesikhumba noma kwamehlo
• kunamafu, umbala ogqamile, noma umchamo onegazi
• ukuhlungu obusemhlane
• ukuchama okunzima noma okubuhlungu
• ukungaboni kahle noma ezinye izinkinga ngokubona

I-Indomethacin ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• isicanucanu
• ukuhlanza
• ikhanda
• isiyezi
• ukudideka
• ukukhathala ngokweqile
• umuzwa wokuba ndikindiki, ukugwazwa, ukushiswa, noma ukukhasa esikhunjeni
• isithuthwane

Ngaphambi kokwenza noma yiluphi uvivinyo lwelabhoratri, tshela udokotela wakho kanye nabasebenzi be-laboratory ukuthi uthatha indomethacin.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Indocin^®
• Tivorbex^®