Ukujova kwe-Estrogen

-Delile

• Ngaphambi kokusebenzisa umjovo we-estrogen,
• Umjovo we-Estrogen ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka:

I-Estrogen inyusa ingozi yokuthi uzoba nomdlavuza we-endometrium (umdlavuza wolwelwesi lwesibeletho [isibeletho]). Uma usebenzisa i-estrogen isikhathi eside, iba nkulu ingozi yokuba nomdlavuza we-endometrium. Uma ungazange uthole i-hysterectomy (ukuhlinzwa ukukhipha isibeletho), kufanele unikezwe omunye umuthi obizwa ngokuthi yi-progestin ozowuthatha ngomjovo we-estrogen. Lokhu kunganciphisa ingozi yokuba nomdlavuza we-endometrium, kepha kungakhuphula ingozi yokuba nezinkinga ezithile zezempilo, kubandakanya umdlavuza webele. Ngaphambi kokuba uqale ukusebenzisa umjovo we-estrogen, tshela udokotela wakho uma uke waba nomdlavuza noma wake waba negazi elingajwayelekile esithweni sangasese. Shayela udokotela wakho ngokushesha uma unegazi elingajwayelekile noma elingajwayelekile ngesikhathi sokwelashwa kwakho ngomjovo we-estrogen. Udokotela wakho uzokubuka eduze ukuze akusize uqinisekise ukuthi awunawo umdlavuza we-endometrial ngesikhathi noma ngemuva kokwelapha kwakho.

Ocwaningweni olukhulu, abesifazane abathathe i-estrogen ngama-progestin ngomlomo babenobungozi obukhulu bokuhlaselwa yisifo senhliziyo, ukushaywa unhlangothi, amahlule egazini emaphashini noma emilenzeni, umdlavuza webele, nokuwohloka komqondo (ukulahlekelwa amandla okucabanga, ukufunda nokuqonda). Abesifazane abasebenzisa umjovo we-estrogen bodwa noma ngama-progestin bangaba nengozi enkulu yokuthuthukisa lezi zimo. Tshela udokotela wakho uma ubhema noma ubhema ugwayi, uma uke wahlaselwa yinhliziyo noma wahlaselwa isifo sohlangothi ngonyaka odlule, futhi uma wena noma omunye emndenini wakho uke waba namahlule egazini noma umdlavuza webele. Phinda utshele udokotela wakho uma uke waba nomfutho wegazi ophakeme noma waba nomfutho ophakeme wegazi, amazinga aphezulu egazi e-cholesterol noma amafutha, isifo sikashukela, isifo senhliziyo, i-lupus (isimo lapho umzimba uhlasela izicubu zawo ezidala ukulimala nokuvuvukala), izigaxa zamabele, noma i-mammogram engajwayelekile (i-x-ray yebele esetshenziselwa ukuthola umdlavuza webele).

Lezi zimpawu ezilandelayo zingaba yizimpawu zezimo ezibucayi zezempilo ezibalwe ngenhla. Shayela udokotela wakho ngokushesha uma uhlangabezana nalezi zimpawu ezilandelayo ngenkathi usebenzisa umjovo we-estrogen: ikhanda elibuhlungu, elibuhlungu ngokuzumayo; ukuhlanza okungazelelwe, okunzima; izinkinga zokukhuluma; isiyezi noma ukuquleka; ukulahleka okungazelelwe okuphelele noma okuncane kombono; ukubona kabili; ubuthakathaka noma ukuba ndikindiki kwengalo noma komlenze; ukuchoboza ubuhlungu besifuba noma isisindo sesifuba; ukukhwehlela igazi; ukuphefumula ngokuzumayo; ubunzima bokucabanga kahle, ukukhumbula, noma ukufunda izinto ezintsha; izigaxa zamabele noma ezinye izinguquko zamabele; khulula izingono; noma ubuhlungu, ubumnene, noma ubomvu emlenzeni owodwa.

Ungathatha izinyathelo ukwehlisa ubungozi bokuthi uzoba nenkinga enkulu yezempilo ngenkathi usebenzisa umjovo we-estrogen. Ungasebenzisi umjovo we-estrogen wedwa noma ne-progestin ukuvikela isifo senhliziyo, isifo senhliziyo, unhlangothi, noma ukuwohloka komqondo. Sebenzisa umthamo ophansi kakhulu we-estrogen olawula izimpawu zakho bese usebenzisa umjovo we-estrogen kuphela uma kudingeka. Khuluma nodokotela wakho njalo ezinyangeni ezi-3-6 ukunquma ukuthi kufanele usebenzise umthamo ophansi we-estrogen noma kufanele uyeke ukusebenzisa umuthi.

Kufanele uhlole amabele akho njalo ngenyanga futhi une-mammogram kanye nokuhlolwa kwebele okwenziwa ngudokotela minyaka yonke ukusiza ukuthola umdlavuza webele ngokushesha ngangokunokwenzeka. Udokotela wakho uzokutshela ukuthi ungawahlola kanjani kahle amabele akho nokuthi ngabe kufanele ube nalezi zivivinyo kaningi ngaphezu kwesisodwa ngonyaka ngenxa yomlando wakho wezempilo noma womndeni.

Tshela udokotela wakho uma uhlinzwa noma uzobe usembhedeni. Udokotela wakho angakutshela ukuthi uyeke ukusebenzisa umjovo we-estrogen emasontweni angama-4-6 ngaphambi kokuhlinzwa noma indawo yokulala ukunciphisa ingozi yokuthi uzoba namahlule egazi.

Khuluma nodokotela wakho njalo ngezingozi nezinzuzo zokusebenzisa umjovo we-estrogen.

Izinhlobo ze-estradiol cypionate kanye ne-estradiol valerate yomjovo we-estrogen zisetshenziselwa ukwelapha ukuqhuma okushisayo (ukushisa okushisayo; imizwa eshisa ngokungazelelwe yokushisa nokujuluka) kanye / noma ukoma kwesitho sangasese sowesifazane, ukulunywa nokushisa kwabesifazane ababhekene nokunqamuka kokuya esikhathini (ushintsho lwempilo; ukuphela kwezikhathi zokuya esikhathini njalo ngenyanga). Kodwa-ke, abesifazane abadinga umuthi kuphela ukwelapha ukoma kwesitho sangasese sowesifazane, ukulunywa, noma ukushiswa kufanele bacabangele ukwelashwa okwehlukile. Lezi zinhlobo zomjovo we-estrogen kwesinye isikhathi zisetshenziselwa ukwelapha izimpawu ze-estrogen ephansi kwabesifazane abasebasha abangakhiqizi i-estrogen eyanele ngokwemvelo. Ifomu le-estradiol valerate lomjovo we-estrogen kwesinye isikhathi lisetshenziselwa ukudambisa izimpawu zezinhlobo ezithile zomdlavuza wesitho sowesilisa (isitho sowesilisa sokuzala). Uhlobo lwe-estrogens oluhlanganisiwe lomjovo we-estrogen lusetshenziselwa ukwelapha ukopha okungajwayelekile kwesitho sangasese sowesifazane udokotela anqume ukuthi kubangelwa inkinga yamanani ama-hormone athile emzimbeni. Umjovo we-Estrogen usesigabeni semithi ebizwa ngamahomoni. Isebenza ngokufaka esikhundleni se-estrogen evame ukukhiqizwa ngumzimba.

Izinhlobo ze-estradiol cypionate ne-estradiol valerate zomjovo omude osebenza nge-estrogen uza njengoketshezi ukujova emisipheni. Le mithi ivamise ukujova ngochwepheshe bezokunakekelwa kwezempilo kanye njalo emavikini ama-3 kuye kwangama-4. Lapho ifomu le-estradiol valerate lomjovo we-estrogen lisetshenziselwa ukwelapha izimpawu zomdlavuza wendlala yabesilisa, livamise ukujova ngochwepheshe bezokunakekelwa kwempilo kanye njalo emavikini ayi-1 kuye kwayi-2.

Uhlobo lwe-estrogens oluhlanganisiwe lomjovo we-estrogen luza njengempuphu yokuxubana namanzi oyinyumba nokujova emsipheni noma emthanjeni. Kuvamise ukujova ngochwepheshe bezokunakekelwa kwezempilo njengomthamo owodwa. Umthamo wesibili ungajova amahora ayisithupha kuya kwayishumi nambili ngemuva komthamo wokuqala uma kudingeka ukulawula ukopha kwesitho sangasese sowesifazane.

Uma usebenzisa umjovo we-estrogen ukwelapha ukuqhuma okushisayo, izimpawu zakho kufanele zithuthuke kungakapheli izinsuku ezi-1 kuye kwezingu-5 ngemuva kokuthola umjovo. Tshela udokotela wakho uma izimpawu zakho zingathuthuki ngalesi sikhathi.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokusebenzisa umjovo we-estrogen,

• Tshela udokotela kanye nosokhemisi wakho uma une-aleji kumjovo we-estrogen, noma imiphi eminye imikhiqizo ye-estrogen, noma imiphi eminye imithi, noma yiziphi izithako zomjovo we-estrogen. Buza usokhemisi wakho noma hlola imininingwane yesiguli yomkhiqizi ukuthola uhlu lwezithako zomkhiqizo womjovo we-estrogen ohlela ukuwusebenzisa.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela noma engabhaliswanga, amavithamini, kanye nezithako zokudla okunomsoco ozithathayo noma ohlela ukuzithatha. Qiniseka ukuthi usho noma ikuphi kokulandelayo: amiodarone (Cordarone, Pacerone); ama-antifungal athile afana ne-itraconazole (Sporanox) ne-ketoconazole (Nizoral); i-aprepitant (Emend); i-carbamazepine (i-Carbatrol, i-Epitol, iTegretol); i-cimetidine (iTagamet); i-clarithromycin (i-Biaxin); i-cyclosporine (iNeoral, iSandimmune); i-dexamethasone (i-Decadron, i-Dexpak); i-diltiazem (Cardizem, Dilacor, Tiazac, abanye); i-erythromycin (E.E.S, Erythrocin); i-fluoxetine (i-Prozac, iSarafem); i-fluvoxamine (i-Luvox); i-griseofulvin (i-Fulvicin, i-Grifulvin, i-Gris-PEG); i-lovastatin (Altocor, Mevacor); imishanguzo yegciwane lesandulela ngculazi (i-HIV) noma i-immunodeficiency syndrome (i-AIDS) efana ne-atazanavir (Reyataz), i-delavirdine (i-Rescriptor), i-efavirenz (i-Sustiva), i-indinavir (i-Crixivan), i-lopinavir (e-Kaletra), i-nelfinavir (i-Viracept), i-nevirapine ( I-Viramune), i-ritonavir (i-Norvir, e-Kaletra), ne-saquinavir (i-Fortovase, i-Invirase); imithi yesifo se-thyroid; nefazodone; i-phenobarbital; i-phenytoin (iDilantin, Phenytek); i-rifabutin (i-Mycobutin); i-rifampin (iRifadin, iRimactane, eRifamate); i-sertraline (iZoloft); troleandomycin (TAO); i-verapamil (Calan, Covera, Isoptin, Verelan); futhi zafirlukast (Accolate). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• utshele udokotela wakho ukuthi uthatha miphi imikhiqizo yamakhambi, ikakhulukazi iSt John's wort.
• Tshela udokotela wakho uma uke waphuza noma waphuka isikhumba noma amehlo ngesikhathi ukhulelwe noma ngesikhathi sokwelashwa kwakho ngomkhiqizo we-estrogen, i-endometriosis (isimo lapho uhlobo lwesicubu esilingana nesibeletho [isibeletho] lukhula kwezinye izindawo umzimba), i-uterine fibroids (ukukhula kwesibeletho okungawona umdlavuza), isifuba somoya, ikhanda elibuhlungu, ukuquleka, i-porphyria (isimo lapho izinto ezingavamile zakha khona egazini futhi zidale izinkinga ngesikhumba noma ngohlelo lwezinzwa), eziphakeme kakhulu noma kakhulu amazinga aphansi we-calcium egazini lakho, noma i-thyroid, isibindi, izinso, i-gallbladder, noma isifo se-pancreatic.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi usebenzisa umjovo we-estrogen, shayela udokotela wakho.

Khuluma nodokotela wakho mayelana nokudla isithelo samagilebhisi nokuphuza ijusi lamagilebhisi ngenkathi usebenzisa lo muthi.

Uma uphuthelwa i-aphoyintimenti yokwamukela umjovo we-estrogen, shayela udokotela wakho ngokushesha okukhulu.

Umjovo we-Estrogen ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ubuhlungu besifuba noma isisa
• isisu esibuhlungu
• ukuhlanza
• ukuzuza kwesisindo noma ukwehla
• isiyezi
• uvalo
• ukudana
• ukucasuka
• izinguquko ezifisweni zocansi
• ukulahleka kwezinwele
• ukukhula kwezinwele okungafuneki
• mnyama mnyama esikhunjeni ebusweni
• ubunzima bokugqoka amalensi wokuxhumana
• amajaqamba omlenze
• ukuvuvukala, ukubomvu, ukushisa, ukulunywa, noma ukucasuka kwesitho sangasese sowesifazane
• ukukhishwa kwesitho sangasese sowesifazane

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:

• Amehlo aqhamukayo
• ubuhlungu, ukuvuvukala, noma ukuthamba esiswini
• ukulahlekelwa isifiso sokudla
• ubuthakathaka
• ukuphuzi kwesikhumba noma kwamehlo
• ubuhlungu obuhlangene
• ukunyakaza okunzima ukulawula
• ukuqubuka noma amabhamuza
• isifuba
• ukulunywa
• ukuvuvukala kwamehlo, ubuso, ulimi, umphimbo, izandla, izingalo, izinyawo, amaqakala noma imilenze engezansi
• ukushaqeka
• ukuphefumula kanzima noma ukugwinya

I-Estrogen ingakhuphula ingozi yokuba nomdlavuza wama-ovari noma isifo se-gallbladder esingadinga ukwelashwa ngokuhlinzwa. Khuluma nodokotela wakho ngezingozi zokusebenzisa umjovo we-estrogen.

I-Estrogen ingadala ukukhula noma ukuyeka kusenesikhathi ezinganeni ezithola amanani amakhulu isikhathi eside. Umjovo we-Estrogen nawo ungathinta isikhathi nesivinini sokukhula kocansi ezinganeni.UDokotela wengane yakho uzomqapha ngokucophelela ngesikhathi eselashwa nge-estrogen. Khuluma nodokotela wengane yakho ngezingozi zokunikeza ingane yakho lo muthi.

Umjovo we-Estrogen ungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Udokotela wakho uzogcina umuthi ehhovisi lakhe.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka:

• isisu esibuhlungu
• ukuhlanza
• ukopha esithweni sangasese

Gcina wonke ama-aphoyintimenti nodokotela wakho.

Ngaphambi kokwenza noma yiluphi uvivinyo lwelabhoratri, tshela udokotela wakho kanye nabasebenzi belebhuthi ukuthi usebenzisa umjovo we-estrogen.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Delestrogen^®
• I-DEPO-Estradiol^®
• Ngaphambi kwangaphambilini^® I.V.

• i-estradiol cypionate
• i-estradiol valerate
• ama-estrogen ahlanganisiwe