I-Desvenlafaxine

-Delile

• Ngaphambi kokuthatha i-desvenlafaxine,
• I-Desvenlafaxine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SESixwayiso noma SOKUQAPHA, shayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka:

Inani elincane lezingane, intsha, nabantu abadala abasebasha (abangafika eminyakeni engama-24 ubudala) abathathe imishanguzo yokulwa nengcindezi ('mood elevators') efana ne-desvenlafaxine phakathi nezifundo zomtholampilo baba ukuzibulala (becabanga ngokuzilimaza noma ukuzibulala noma ukuhlela noma ukuzama ukwenza kanjalo ). Izingane, intsha, kanye nabantu abadala abasebancane abathatha imishanguzo yokulwisana nokucindezelwa ukwelapha ukudangala noma ezinye izifo zengqondo bangase babe sethubeni lokuzibulala kunezingane, intsha kanye nabantu abadala abangawasebenzisi ama-anti-depressants ukwelapha lezi zimo. Kodwa-ke, ochwepheshe abaqiniseki ngokuthi le ngozi ingakanani nokuthi kufanele icatshangelwe kangakanani ekunqumeni ukuthi ingane noma osemusha kufanele yini athathe i-anti-depressant. Izingane ezingaphansi kweminyaka engu-18 ubudala akufanele zivame ukuthatha i-desvenlafaxine, kodwa kwezinye izimo, udokotela anganquma ukuthi i-desvenlafaxine iyimithi engcono kakhulu yokwelapha isimo sengane.

Kufanele wazi ukuthi impilo yakho yengqondo ingashintsha ngezindlela ezingalindelekile lapho uthatha i-desvenlafaxine noma amanye ama-anti-depressants noma ngabe umdala ngaphezu kweminyaka engama-24. Ungase uzibulale, ikakhulukazi ekuqaleni kokwelashwa kwakho futhi nganoma yisiphi isikhathi lapho umthamo wakho wanda noma wehla. Wena, umndeni wakho, noma umnakekeli wakho kufanele ushayele udokotela wakho ngokushesha uma uhlangabezana nalezi zimpawu ezilandelayo: ukucindezeleka okusha noma okuya kuba kubi; ukucabanga ngokuzilimaza noma ukuzibulala, noma ukuhlela noma ukuzama ukwenza kanjalo; ukukhathazeka ngokweqile; ukuyaluza; ukwethuka; ubunzima bokulala noma ukulala; isimilo esinolaka; ukucasuka; ukwenza ngaphandle kokucabanga; ukungahlaliseki okukhulu; noma isasasa elingajwayelekile. Qiniseka ukuthi umndeni wakho noma umnakekeli wakho uyazi ukuthi yiziphi izimpawu ezingaba zimbi kakhulu ukuze bakwazi ukubiza udokotela uma ungakwazi ukuzifunela ukwelashwa wedwa.

Umhlinzeki wakho wezokunakekelwa kwempilo uzofuna ukukubona kaningi ngenkathi uthatha i-desvenlafaxine, ikakhulukazi ekuqaleni kokwelashwa kwakho. Qiniseka ukuthi ugcina wonke ama-aphoyintimenti wokuvakashelwa ehhovisi nodokotela wakho.

Udokotela noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa nge-desvenlafaxine.Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungathola futhi i-Medication Guide kuwebhusayithi ye-FDA: http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm.

Akunandaba ukuthi uneminyaka emingaki, ngaphambi kokuba uthathe i-anti-depressant, wena, umzali wakho, noma umnakekeli wakho kufanele ukhulume nodokotela wakho ngezingozi nezinzuzo zokwelapha isimo sakho nge-anti-depressant noma ngezinye izindlela zokwelapha. Kufanele futhi ukhulume ngobungozi nezinzuzo zokungaselaphi isimo sakho. Kufanele wazi ukuthi ukuba nokudangala noma esinye isifo sengqondo kusandisa kakhulu ingozi yokuthi uzozibulala. Le ngozi ingaphezulu uma wena noma omunye emndenini wakho unenkinga yokuphazamiseka kwengqondo okuguquguqukayo (imizwa eguquka isuke ekucindezelekeni iye ekuthokozeni okungavamile) noma imania (edidekile, ejabule ngokweqile) noma uke wacabanga noma wazama ukuzibulala. Khuluma nodokotela wakho ngesimo sakho, izimpawu zakho, nomlando wakho wezempilo nowomndeni. Wena nodokotela wakho niyonquma ukuthi hlobo luni lwezokwelapha olulungele nina.

I-Desvenlafaxine isetshenziselwa ukwelapha ukucindezeleka. UDesvenlafaxine usesigabeni semithi ebizwa nge-serotonin ekhethiwe ne-norepinephrine reuptake inhibitors (SNRIs). Isebenza ngokwandisa inani le-serotonin ne-norepinephrine, izinto zemvelo ebuchosheni ezisiza ukugcina ukulinganisela kwengqondo.

IDesvenlafaxine iza njengethebhulethi ekhishwe isikhathi eside (esebenza isikhathi eside) ezothathwa ngomlomo. Imvamisa kuthathwa kanye ngosuku noma ngaphandle kokudla. Thatha i-desvenlafaxine ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-desvenlafaxine njengoba nje kuqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Gwinya wonke amaphilisi ngamanzi amaningi; ungawahlukanisi, ungawahlafune, uwachoboze noma uwaqede.

I-Desvenlafaxine ilawula ukudangala, kepha ayiyelaphi. Kungathatha amasonto ambalwa ngaphambi kokuba uzwe inzuzo ephelele ye-desvenlafaxine. Qhubeka uthathe i-desvenlafaxine noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-desvenlafaxine ngaphandle kokukhuluma nodokotela wakho. Udokotela wakho mhlawumbe uzokwehlisa umthamo wakho kancane kancane. Uma ngokungazelelwe uyeka ukuthatha i-desvenlafaxine, ungahlangabezana nezimpawu zokuhoxa ezifana nesiyezi, ukudideka, isicanucanu, ikhanda, ukukhala ezindlebeni, ukucasuka, ukungakwazi ukulawula imizwa, ukuguquka kwemizwelo njalo, ukujabula ngokweqile, ubunzima bokulala noma ukulala, isifo sohudo, ukukhathazeka, ukukhathala ngokweqile, amaphupho angajwayelekile, ukuquleka, ukujuluka, ukuqhaqhazela okungalawuleki kwengxenye yomzimba, noma ubuhlungu, ukushisa noma ukuncinza ezandleni noma ezinyaweni. Tshela udokotela wakho uma uhlangabezana nalezi zimpawu ngenkathi unciphisa umthamo wakho we-desvenlafaxine noma ngemuva nje kokuyeka ukuthatha i-desvenlafaxine.

I-Desvenlafaxine kwesinye isikhathi isetshenziselwa ukwelapha ukushisa (ukushisa okushisayo; imizwa eshubile engazelelwe yokushisa nokujuluka) kwabesifazane abaye babhekana nokunqamuka kokuya esikhathini ('ushintsho lwempilo'; ukuphela kwezikhathi zokuya esikhathini njalo ngenyanga). Khuluma nodokotela wakho ngezingozi zokusebenzisa lo muthi ngesimo sakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-desvenlafaxine,

• Tshela udokotela kanye nosokhemisi wakho uma une-aleji ye-desvenlafaxine, i-venlafaxine (i-Effexor), noma imiphi eminye imishanguzo, noma yiziphi izithako ezikumaphilisi e-desvenlafaxine. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
• Tshela udokotela wakho uma uthatha i-monoamine oxidase (MAO) inhibitor, efana ne-isocarboxazid (Marplan), linezolid (Zyvox), methylene blue, phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), ne-tranylcypromine (iParnate), noma uma uyekile ukuthatha owodwa wale mithi ezinsukwini eziyi-14 ezedlule. Udokotela wakho mhlawumbe uzokutshela ukuthi akufanele uthathe i-desvenlafaxine. Uma uyeka ukuthatha i-desvenlafaxine, udokotela wakho uzokutshela ukuthi kufanele ulinde okungenani izinsuku eziyi-7 ngaphambi kokuqala ukuthatha i-MAO inhibitor.
• kufanele wazi ukuthi i-desvenlafaxine ifana kakhulu nenye i-SNRI, venlafaxine (Effexor). Akufanele uthathe le mithi ndawonye.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela noma ongayinikezwa noma amavithamini owathathayo noma ohlela ukuwaphuza. Qinisekisa ukusho noma yikuphi kokulandelayo: ama-amphetamine afana ne-amphetamine (e-Adderall), i-dextroamphetamine (i-Dexedrine, i-Dextrostat, e-Adderall), ne-methamphetamine (i-Desoxyn); ama-anticoagulants (’ama-thinner egazi’) afana ne-warfarin (Coumadin); ama-antifungal athile afana ne-itraconazole (Sporanox) ne-ketoconazole (Nizoral); amiodarone (Cordarone, Pacerone); i-aspirin nezinye izidakamizwa ezingezona ukuvuvukala (ama-NSAID) njenge-ibuprofen (Advil, Motrin) ne-naproxen (Aleve, Naprosyn); i-atomoxetine (iStraterra); ibuspirone (Buspar); i-clarithromycin (i-Biaxin); i-dextromethorphan (etholakala emithini eminingi yokukhwehlela; eNuedexta); isisu (‘amaphilisi amanzi’); i-fentanyl (i-Actiq, i-Duragesic, i-Fentora); lithium (Eskalith, Lithobid); imithi yokukhathazeka, ukugula kwengqondo, noma ukuquleka; imishanguzo ethile yegciwane lengculazi (i-HIV) njenge-indinavir (Crixivan), i-nelfinavir (i-Viracept), ne-ritonavir (i-Norvir); imithi ye-migraine efana ne-almotriptan (Axert), i-eletriptan (i-Relpax), i-frovatriptan (i-Frova), i-naratriptan (i-Amerge), i-rizatriptan (i-Maxalt), i-sumatriptan (i-Imitrex), ne-zolmitriptan (i-Zomig); i-metoprolol (iLopressor, iTrolrol XL); i-midazolam; i-nebivolol (Bystolic); nefazodone; i-perphenazine (ku-Duo-Vil); isidambisi; i-serotonin reuptake inhibitors (SSRIs) ekhethiwe efana ne-citalopram (Celexa), i-escitalopram (Lexapro), i-fluoxetine (i-Prozac, i-Sarafem), i-fluvoxamine (i-Luvox), i-paroxetine (i-Paxil), ne-sertraline (i-Zoloft); amanye ama-SNRI afana ne-duloxetine (Cymbalta); sibutramine (Meridia); amaphilisi okulala; i-tolterodine (i-Detrol); i-tramadol (i-Ultram); okokunciphisa umzimba; kanye ne-tricyclic antidepressants efana ne-amitriptyline, amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Sinequan), imipramine (Tofranil), nortriptyline (Aventyl, Pamelor), protriptyine (Vivactiline) Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo eminingi ingaxhumana ne-desvenlafaxine, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu.
• utshele udokotela wakho ukuthi yimiphi imikhiqizo yamakhambi kanye nezithako zokudla okunomsoco ozithathayo, ikakhulukazi iSt John's wort ne-tryptophan.
• utshele udokotela wakho uma usebenzisa noma wake wasebenzisa izidakamizwa zasemgwaqeni noma uke wasebenzisa ngokweqile imithi kadokotela. Phinda utshele udokotela wakho uma usanda kuhlaselwa yinhliziyo futhi uma uke waba nezinkinga zokopha; isifo sohlangothi; umfutho wegazi ophakeme; i-cholesterol ephezulu noma i-triglycerides (amafutha egazini); amazinga aphansi e-sodium egazini; noma isifo senhliziyo, sezinso, noma sesibindi.
• Tshela udokotela wakho uma ukhulelwe, ikakhulukazi uma usezinyangeni ezimbalwa ezedlule zokukhulelwa kwakho, noma uma uhlela ukukhulelwa noma ukuncelisa. Uma ukhulelwa ngenkathi uthatha i-desvenlafaxine, shayela udokotela wakho. I-Desvenlafaxine ingadala izinkinga ezinganeni ezisanda kuzalwa ngemuva kokubeletha uma zithathwa ezinyangeni zokugcina zokukhulelwa.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi uthatha i-desvenlafaxine.
• kufanele wazi ukuthi i-desvenlafaxine ingakwenza ukozele. Ungashayeli imoto noma usebenzise imishini uze wazi ukuthi lo muthi ukuthinta kanjani.
• buza udokotela wakho mayelana nokusetshenziswa okuphephile kweziphuzo ezidakayo ngenkathi uthatha i-desvenlafaxine. Utshwala bungenza imiphumela emibi evela ku-desvenlafaxine ibe yimbi kakhulu.
• kufanele wazi ukuthi kubantu abadala asebekhulile, i-desvenlafaxine ingadala isiyezi, ikhanda elikhanyayo, nokuquleka lapho uvuka ngokushesha okukhulu kusuka endaweni yokulala. Ukugwema le nkinga, phuma embhedeni kancane, uphumule izinyawo zakho phansi imizuzu embalwa ngaphambi kokuma.
• kufanele wazi ukuthi i-desvenlafaxine ingadala i-angle-closure glaucoma (isimo lapho uketshezi luvinjwe ngokuzumayo futhi lungakwazi ukuphuma esweni kubangele ukwanda okusheshayo, okunzima kwengcindezi yamehlo okungaholela ekulahlekelweni kombono). Khuluma nodokotela wakho ngokuhlolwa iso ngaphambi kokuba uqale ukusebenzisa le mithi. Uma unesicanucanu, ubuhlungu beso, izinguquko embonweni, njengokubona izindandatho ezinemibala ezungeze izibani, nokuvuvukala noma ukubomvu ngaphakathi noma ezungeze iso, shayela udokotela wakho noma uthole ukwelashwa okuphuthumayo ngokushesha.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Desvenlafaxine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ukuqunjelwa
• ukulahlekelwa isifiso sokudla
• umlomo owomile
• isiyezi
• ukukhathala ngokweqile
• amaphupho angajwayelekile
• kuzamula
• ukujuluka
• ukuzamazama okungalawuleki kwengxenye yomzimba
• ubuhlungu, ukuvutha, ukuba ndikindiki, noma ukushosheka engxenyeni ethile yomzimba
• abafundi abakhulisiwe (imibuthano emnyama ezindaweni zamehlo)
• izinguquko kwisifiso sobulili noma ikhono
• ubunzima bokuchama

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SESixwayiso noma SOKUQAPHA, shayela udokotela wakho ngokushesha:

• ukuqubuka
• isifuba
• ukuvuvukala kobuso, umphimbo, ulimi, izindebe, amehlo, izandla, izinyawo, amaqakala noma imilenze engezansi
• ukushaqeka
• ubunzima bokugwinya noma ukuphefumula
• ukushaya kwenhliziyo okusheshayo
• ukukhwehlela
• isifuba, ingalo, iqolo, intamo, noma ubuhlungu bomhlathi
• imfiva
• ikhoma (ukulahlekelwa ukwazi isikhathi esithile)
• isithuthwane
• ukusangana (ukubona izinto noma ukuzwa amazwi angekho)
• umkhuhlane, ukujuluka, ukudideka, ukushaya kwenhliziyo okusheshayo noma okungajwayelekile, nokuqina kwemisipha okunzima
• ukopha okungajwayelekile noma ukulinyazwa
• ukuphuma kwamakhala
• amachashazi amancane abomvu noma ansomi esikhunjeni
• isicanucanu
• ukuhlanza
• isifo sohudo
• ikhanda
• ubunzima bokugxila
• izinkinga zememori
• ukudideka
• ubuthakathaka
• izinkinga ngokuxhumanisa
• ukwanda kokuwa
• ukuquleka

I-Desvenlafaxine ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka:

• ikhanda
• ukuhlanza
• ukuyaluza
• isiyezi
• isicanucanu
• ukuqunjelwa
• isifo sohudo
• umlomo owomile
• ubuhlungu, ukuvutha, ukuba ndikindiki, noma ukushosheka engxenyeni ethile yomzimba
• ukushaya kwenhliziyo okusheshayo

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzohlola umfutho wegazi lakho kaningi futhi anga-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ku-desvenlafaxine.

Ngaphambi kokwenza noma yiluphi uvivinyo lwelabhoratri, tshela udokotela wakho kanye nabasebenzi baselebhu ukuthi uthatha i-desvenlafaxine.

Ithebhulethi ekhishwe isikhathi eside ayincibiliki esiswini ngemuva kokugwinya. Uwukhipha kancane umuthi njengoba udlula ohlelweni lwakho lokugaya ukudla. Ungaqaphela ukumbozwa kwethebhulethi esitokisini. Lokhu kujwayelekile futhi akusho ukuthi awutholanga umthamo ophelele wemithi.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• UPristiq^®