Ukujova kwe-Bendamustine

-Delile

• Ngaphambi kokuthola umjovo we-bendamustine,
• Umjovo we-Bendamustine ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
• Izimpawu zokudlula ngokweqile zingafaka:

Umjovo we-Bendamustine usetshenziselwa ukwelapha i-lymphocytic leukemia (CLL; uhlobo lomdlavuza wamaseli amhlophe egazi). Umjovo we-Bendamustine uphinde usetshenziselwe ukwelapha uhlobo lwe-non-Hodgkins lymphoma (NHL: umdlavuza oqala ohlotsheni lwamaseli amhlophe egazi alwa nokutheleleka) okuhamba kancane ukusabalala, kepha okuqhubekile nokuba kubi kakhulu ngesikhathi nangemva kokwelashwa ngomunye umuthi. I-Bendamustine isekilasini lemithi ebizwa ngama-alkylating agents. Isebenza ngokubulala amangqamuzana omdlavuza akhona nokunciphisa ukukhula kwamangqamuzana omdlavuza amasha.

I-Bendamustine iza njengesisombululo (uketshezi) noma njengempuphu ezoxutshwa noketshezi futhi ifakwe ngomjovo (emthanjeni) ngaphezulu kwemizuzu eyi-10 noma ifakwe ngaphakathi ngemizuzu engaphezu kwengama-30 noma engama-60 ngudokotela noma umhlengikazi ehhovisi lezokwelapha noma emtholampilo wabangalaliswa esibhedlela. Lapho umjovo we-bendamustine usetshenziselwa ukwelapha i-CLL, uvamise ukujova kanye ngosuku izinsuku ezimbili, kulandelwe izinsuku ezingama-26 lapho umuthi unganikezwa. Le nkathi yokwelashwa ibizwa ngokuthi umjikelezo, futhi umjikelezo ungaphindwa njalo ezinsukwini ezingama-28 isikhathi eside njengokufika kwemijikelezo engu-6. Lapho umjovo we-bendamustine usetshenziselwa ukwelapha i-NHL, uvamise ukujova kanye ngosuku izinsuku ezimbili, kulandelwe izinsuku eziyi-19 lapho umuthi unganikezwa. Lo mjikelezo wokwelashwa ungaphindwa njalo ezinsukwini ezingama-21 kuze kube yimijikelezo engu-8.

Udokotela wakho angadinga ukubambezela ukwelashwa kwakho futhi alungise umthamo wakho uma uhlangabezana nemiphumela ethile emibi. Udokotela wakho angakunikeza neminye imithi ukuvimbela noma ukwelapha imiphumela ethile engemihle. Qiniseka ukuthi utshela udokotela wakho ukuthi uzizwa kanjani ngenkathi welashwa ngomjovo we-bendamustine.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola umjovo we-bendamustine,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-bendamustine, noma imiphi eminye imithi, noma yiziphi izithako zomjovo we-bendamustine. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: i-ciprofloxacin (Cipro), i-fluvoxamine (i-Luvox, ne-omeprazole (i-Prilosec). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imithi eminingi ingaxhumana ne-bendamustine , ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu.
• Tshela udokotela wakho uma ngabe uke waba nokutheleleka nge-cytomegalovirus (CMV; ukutheleleka ngegciwane okungadala izimpawu ezigulini ezinamasosha omzimba abuthakathaka), ukutheleleka ngegciwane le-hepatitis B (HBV; ukutheleleka kwesibindi okuqhubekayo), isifo sofuba (i-TB; isifo esibi lokho kuthinta amaphaphu futhi kwesinye isikhathi nezinye izingxenye zomzimba), i-herpes zoster (i-shingles; ukuqubuka okungenzeka kubantu abake baba nenkukhu ngaphambilini), noma isifo sezinso noma sesibindi.
• tshela udokotela wakho uma ukhulelwe noma uhlela ukukhulelwa, noma uma uhlela ukuba nobaba wengane. Wena noma umlingani wakho akufanele ukhulelwe ngenkathi uthola umjovo we-bendamustine. Kufanele usebenzise ukulawulwa kokubeletha ukuvimbela ukukhulelwa kuwe noma kumlingani wakho ngesikhathi sokwelashwa kwakho ngomjovo we-bendamustine nezinyanga ezi-3 ngemuva kwalokho. Khuluma nodokotela wakho ngezindlela zokulawula ukubeletha ezizokusebenzela. Uma wena noma umlingani wakho ukhulelwa ngenkathi uthola umjovo we-bendamustine, shayela udokotela wakho. Umjovo we-Bendamustine ungalimaza umbungu.
• tshela udokotela wakho uma uncelisa. Akufanele uncelise ibele ngesikhathi sokwelashwa kwakho nge-bendamustine.
• kufanele wazi ukuthi umjovo we-bendamustine ungakudinisa. Ungashayeli imoto noma usebenzise imishini uze wazi ukuthi lo muthi ukuthinta kanjani.
• utshele udokotela wakho uma usebenzisa imikhiqizo kagwayi. Ukubhema kunganciphisa ukusebenza kwalo muthi.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Shayela udokotela wakho ngokushesha uma ungakwazi ukugcina i-aphoyintimenti ukuze uthole umthamo womjovo we-bendamustine.

Umjovo we-Bendamustine ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isicanucanu
• ukuhlanza
• isifo sohudo
• isilungulela
• ukuqunjelwa
• ubuhlungu besisu noma ukuvuvukala
• izilonda noma amabala amhlophe emlonyeni
• umlomo owomile
• ukunambitheka kabi emlonyeni noma ubunzima bokunambitha ukudla
• ukulahlekelwa isifiso sokudla
• ukuncipha komzimba
• ikhanda
• ukukhathazeka
• ukudana
• ubunzima bokulala noma ukulala
• iqolo, ithambo, amalunga, ingalo noma ubuhlungu bomlenze
• isikhumba esomile
• ukujuluka
• ukujuluka ebusuku

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ubuhlungu endaweni lapho umjovo wafakwa khona
• isifuba
• ukuqubuka
• ukulunywa
• isikhumba esishayayo noma esikhanyayo
• ukuphefumula kanzima noma ukugwinya
• ukuvuvukala kwamehlo, ubuso, izindebe, ulimi, izingalo, izandla, izinyawo, amaqakala noma imilenze engezansi
• ukuphelelwa umoya
• ubuhlungu besifuba
• ukushaya kwenhliziyo okusheshayo
• ukukhathala ngokweqile noma ubuthakathaka
• isikhumba esiphaphathekile
• umkhuhlane, ukubanda, ukukhwehlela, noma ezinye izimpawu zokutheleleka
• isicanucanu; ukuhlanza; ukopha okungavamile noma ukulimaza; ukuphuzi kwesikhumba noma kwamehlo, umchamo omnyama, noma isitulo esinombala okhanyayo; ubumnene ohlangothini olungakwesokudla olungaphezulu kwesisu

Umjovo we-Bendamustine ungadala ukungabi nenzalo kwamanye amadoda. Lokhu kuzala kungaphela ngemuva kokwelashwa, kungahlala iminyaka eminingana, noma kungahlala unomphela. Khuluma nodokotela wakho ngezingozi zokuthola lo muthi.

Abanye abantu bahlakulela ezinye izinhlobo zomdlavuza ngenkathi besebenzisa umjovo we-bendamustine. Akukho lwazi olwanele lokutshela ukuthi umjovo we-bendamustine ubangele ukuthi le mikhamo ikhule. Khuluma nodokotela wakho ngezingozi zokuthola lo muthi.

Umjovo we-Bendamustine ungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthola lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka:

• ukushaya kwenhliziyo okusheshayo, okungajwayelekile, noma okushaya ngamandla

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho kumjovo we-bendamustine.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

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