Isihloko se-Bexarotene

-Delile

• Ukuze usebenzise ijeli, landela lezi zinyathelo:
• Ngaphambi kokusebenzisa i-bexarotene,
• Izihloko ze-bexarotene zingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

I-bexarotene yama-topical isetshenziselwa ukwelapha i-T-cell lymphoma (CTCL, uhlobo lomdlavuza wesikhumba) olungenakwelashwa ngeminye imithi. UBexarotene usesigabeni semithi ebizwa ngama-retinoids. Isebenza ngokumisa ukukhula kwamangqamuzana omdlavuza.

I-bexarotene eyisihloko iza njengejeli ukufaka esikhumbeni. Imvamisa isetshenziswa kanye njalo ngosuku lokuqala futhi kancane kancane isetshenziswe kaningi kuze kube kabili noma kane ngosuku. Sebenzisa i-bexarotene yama-topical ngezikhathi ezifanayo nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Sebenzisa i-bexarotene njengoba nje kuqondisiwe. Ungayisebenzisi ngaphezulu noma ngaphansi kwayo noma uyisebenzise kaningi kunokuyalelwa ngudokotela wakho.

Udokotela wakho mhlawumbe uzokuqala ngomthamo ophansi we-bexarotene yama-topical futhi akhuphule kancane umthamo wakho, hhayi kaningi ngesonto. Udokotela wakho anganciphisa umthamo wakho uma uba nemiphumela emibi.

Isimo sakho singathuthuka ngokushesha ngemuva kwamaviki ama-4 ngemuva kokuqala ukusebenzisa i-bexarotene, noma kungathatha izinyanga ezimbalwa ngaphambi kokuthi ubone noma yikuphi ukuthuthuka. Qhubeka nokusebenzisa i-bexarotene eyisihloko ngemuva kokubona ukuthuthuka; isimo sakho singaqhubeka nokuba ngcono. Ungayeki ukusebenzisa i-bexarotene yama-topical ngaphandle kokukhuluma nodokotela wakho.

Ijeli yeBexarotene ingasha. Ungayisebenzisi le mithi eduze komthombo wokushisa noma eduze kwelangabi elivulekile njengogwayi.

Ijel Bexarotene ingeyokusetshenziswa kwangaphandle kuphela. Ungayigwinyi imithi futhi ugcine umuthi kude namehlo akho, amakhala, umlomo, izindebe, isitho sangasese sowesifazane, ipipi lepipi, i-rectum kanye ne-anus.

Ungageza, ugeze, noma ubhukude ngesikhathi sokwelashwa kwakho nge-bexarotene, kodwa kufanele usebenzise kuphela insipho emnene, engeyona iphunga. Kufanele ulinde okungenani imizuzu engama-20 ngemuva kokugeza noma ukugeza ngaphambi kokufaka i-bexarotene eyisihloko. Ngemuva kokufaka umuthi, ungagezi, ungabhukudi noma ugeze okungenani amahora amathathu.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Ukuze usebenzise ijeli, landela lezi zinyathelo:

1. Geza izandla zakho.
2. Uma usebenzisa ithubhu entsha yejeli ye-bexarotene, susa ikepisi bese uhlola ukuthi ukuvulwa kweshubhu kumbozwe ngophawu lokuphepha lwensimbi. Ungayisebenzisi ishubhu uma ungayiboni uphawu lokuphepha noma uma uphawu lubhoboziwe. Uma ubona uphawu lokuphepha, jikisa ikepisi ubheke phansi bese usebenzisa iphuzu elibukhali ukubhoboza uphawu.
3. Sebenzisa umunwe ohlanzekile ukufaka isendlalelo esivulekile sejel endaweni ezolashwa kuphela. Qaphela ukuthi ungatholi i-gel esikhunjeni esinempilo esizungeze indawo ethintekile. Ungayihlikihli ijeli esikhunjeni. Kufanele ukwazi ukubona ijeli endaweni ethintekile ngemuva kokuqeda ukuyisebenzisa.
4. Ungayimbozi indawo elashwawe ngebhandishi eliqinile noma ngokugqoka ngaphandle uma utshelwe ngudokotela wakho ukuthi wenze njalo.
5. Sula umunwe owawusebenzisa ukufaka ijeli ngesicubu bese ulahla izicubu. Geza izandla zakho ngensipho namanzi.
6. Vumela ijeli ukuthi lome imizuzu emi-5 kuya kwengu-10 ngaphambi kokumboza ngezingubo ezikhululekile. Ungagqoki izingubo eziqinile endaweni ethintekile.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokusebenzisa i-bexarotene,

• utshele udokotela wakho kanye nosokhemisi uma unegciwane ku-bexarotene; noma iyiphi enye i-retinoid efana ne-acitretin (Soriatane), etretinate (Tegison), isotretinoin (Accutane), noma i-tretinoin (Vesanoid); noma yimuphi omunye umuthi.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: ama-antifungal athile afana ne-ketoconazole (Nizoral) ne-itraconazole (Sporanox); i-erythromycin (i-E.E.S., i-E-Mycin, i-Erythrocin); gemfibrozil (Lopid); eminye imithi noma imikhiqizo efakwa esikhunjeni; novithamini A (kumavithamini amaningi). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imithi eminingi ingase futhi ihlanganyele ne-bexarotene yama-topical, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho nalawo angaveli kulolu hlu.
• tshela udokotela wakho uma uke waba nesifo sezinso noma sesibindi.
• utshele udokotela wakho uma ukhulelwe noma uhlela ukukhulelwa. I-bexarotene eyisihloko ingadala ukukhubazeka okukhulu kokuzalwa, ngakho-ke kuzodingeka uthathe izinyathelo zokuvikela ukukhulelwa ngesikhathi nangemva nje kokwelapha kwakho. Uzoqala ukwelashwa kwakho ngosuku lwesibili noma lwesithathu esikhathini sakho sokuya esikhathini, futhi kuzodingeka ukuthi ube nokuhlolwa kokukhulelwa okungekuhle kungakapheli isonto elilodwa uqale ukwelashwa kwakho kanye kanye ngenyanga ngemuva kokwelashwa kwakho. Kufanele usebenzise izindlela ezi-2 ezamukelekile zokulawulwa kokubeletha ngesikhathi sokwelashwa kwakho nenyanga eyodwa ngemuva kokwelashwa kwakho. Uma ukhulelwa ngesikhathi sokwelashwa kwakho nge-bexarotene yama-topical, shayela udokotela wakho ngokushesha.
• tshela udokotela wakho uma uncelisa.
• uma ungowesilisa futhi unomlingani okhulelwe noma ongakhulelwa, khuluma nodokotela wakho mayelana nezinyathelo okufanele uzithathe ngenkathi welashwa. Shayela udokotela wakho ngokushesha uma umlingani wakho ekhulelwa ngenkathi usebenzisa i-bexarotene.
• hlela ukugwema ukuvezwa yilanga nezibani zelanga ngokungadingekile noma isikhathi eside futhi ugqoke izingubo zokuzivikela, izibuko zelanga, kanye nezigcobo zelanga. Izihloko ze-bexarotene zingenza isikhumba sakho sizwele elangeni.
• ungasebenzisi iziphikisi zezinambuzane noma eminye imikhiqizo equkethe i-DEET ngesikhathi sokwelashwa kwakho nge-bexarotene yama-topical.
• musa ukuklwebha izindawo ezithintekile ngesikhathi sokwelashwa kwakho nge-bexarotene yama-topical.

Khuluma nodokotela wakho mayelana nokudla isithelo samagilebhisi nokuphuza ijusi lamagilebhisi ngenkathi usebenzisa lo muthi.

Sebenzisa umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungafaki i-gel eyengeziwe ukwenzela umthamo ophuthelwe.

Izihloko ze-bexarotene zingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ukulunywa
• ububomvu, ukuvutha, ukucasuka, noma ukukala kwesikhumba
• ukuqubuka
• ubuhlungu
• ukujuluka
• ubuthakathaka
• ikhanda
• ukuvuvukala kwezingalo, izandla, izinyawo, amaqakala, noma imilenze engezansi

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

• umphimbo obuhlungu, umkhuhlane, ukubanda, noma ezinye izimpawu zokutheleleka
• izindlala ezivuvukele

I-Bexarotene ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi usebenzisa lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivaleke ngci, futhi ingafinyeleleki futhi ingabonakali ezinganeni. Ukugcine ekamelweni lokushisa kude nokukhanya, ukushisa okweqile, amalangabi avulekile, nomswakama (hhayi endlini yangasese).

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Gcina wonke ama-aphoyintimenti nodokotela wakho.

Ungavumeli omunye umuntu asebenzise imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Targretin^® I-Gel yezihloko