Inaliti yeRomiplostim

-Delile

• Ngaphambi kokuthola umjovo we-romiplostim,
• Umjovo we-Romiplostim ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

Umjovo we-Romiplostim usetshenziselwa ukukhulisa inani lama-platelet (amaseli asiza igazi ukuba livale) ukuze kuncishiswe ingozi yokopha kubantu abadala abane-immune thrombocytopenia (ITP; idiopathic thrombocytopenic purpura; isimo esiqhubekayo esingadala ukulimazeka noma ukopha kalula ngenxa yenani eliphansi ngokungajwayelekile lamagazi egazini). Umjovo weRomiplostim nawo usetshenziselwa ukukhulisa inani lama-platelet ukunciphisa ingozi yokuphuma kwegazi ezinganeni okungenani unyaka owodwa ubudala obene-ITP okungenani izinyanga eziyisithupha. Umjovo we-Romiplostim kufanele usetshenziswe kuphela kubantu abadala kanye nezingane ezineminyaka engu-1 ubudala noma ngaphezulu abangakwazi ukwelashwa noma abangazange basizwe ezinye izindlela zokwelapha, kufaka phakathi eminye imithi noma ukuhlinzwa ukususa ubende. Umjovo weRomiplostim akufanele usetshenziselwe ukwelapha abantu abanamazinga aphansi eplatelet abangelwa i-myelodysplastic syndrome (iqembu lezimo lapho umnkantsha ukhiqiza khona amaseli egazi angafakwanga kahle futhi angavezi amaseli egazi anempilo) noma ezinye izimo ezibanga amazinga eplatelet ngaphandle kwe-ITP. Umjovo we-Romiplostim usetshenziselwa ukukhulisa inani lama-platelet anele ukwehlisa ubungozi bokuphuma kwegazi, kepha alisetshenziswanga ukukhulisa inani lama-platelet libe sezingeni elijwayelekile. URomiplostim usesigabeni semithi ebizwa ngama-thrombopoietin receptor agonists. Isebenza ngokwenza amaseli emnkantsheni wethambo akhiqize ama-platelet amaningi.

Umjovo weRomiplostim uza njengempuphu ezohlanganiswa noketshezi oluzofakwa ngaphansi kwesikhumba) ngudokotela noma umhlengikazi ehhovisi lezokwelapha. Kuvame ukujova kanye ngesonto.

Udokotela wakho mhlawumbe uzokuqala ngomthamo ophansi womjovo we-romiplostim futhi alungise umthamo wakho, hhayi ngaphezu kwesisodwa njalo ngesonto. Ekuqaleni kokwelashwa kwakho, udokotela wakho uzokuyalela ukuhlolwa kwegazi ukubheka izinga leplatelet yakho kanye ngesonto. Udokotela wakho angakhuphula umthamo wakho uma izinga leplatelet lakho liphansi kakhulu. Uma izinga lakho leplatelet liphezulu kakhulu, udokotela wakho anganciphisa umthamo wakho noma angakuniki umuthi nhlobo. Ngemuva kokuthi ukwelashwa kwakho kuqhubeke isikhathi esithile futhi udokotela wakho ethole umthamo okusebenzelayo, izinga lakho leplatelet lizohlolwa kanye ngenyanga. Izinga lakho leplatelet lizobhekwa okungenani amasonto ama-2 ngemuva kokuqeda ukwelashwa kwakho ngomjovo we-romiplostim.

Umjovo weRomiplostim awusebenzi kuwo wonke umuntu. Uma izinga lakho leplatelet lingakhuli ngokwanele ngemuva kokuthola umjovo we-romiplostim isikhathi esithile, udokotela wakho uzoyeka ukukunika umuthi. Udokotela wakho futhi anga-oda ukuhlolwa kwegazi ukuthola ukuthi kungani umjovo we-romiplostim ungakusebenzelanga.

Umjovo weRomiplostim ulawula i-ITP kepha ayiyelaphi. Qhubeka nokugcina ama-aphoyintimenti ukuthola umjovo we-romiplostim noma ngabe uzizwa uphilile.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa ngomjovo we-romiplostim. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs) noma iwebhusayithi yomkhiqizi ukuthola uMhlahlandlela Wezokwelapha.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola umjovo we-romiplostim,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-romiplostim injection noma yimuphi omunye umuthi.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi kokulandelayo: ama-anticoagulants (ama-thinner egazi) njenge-warfarin (i-Coumadin); i-aspirin nezinye izidakamizwa ezingezona ukuvuvukala (ama-NSAID) njenge-ibuprofen (Advil, Motrin) ne-naproxen (Aleve, Naprosyn); i-cilostazol (i-Pletal); i-clopidogrel (i-Plavix); i-dipyridamole (Aggrenox); i-heparin; kanye ne-ticlopidine (Ticlid). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo eminingi ingaxhumana ne-romiplostim, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho nalawo angaveli kulolu hlu.
• Tshela udokotela wakho uma uke waba negazi noma waba nezinkinga zokopha, noma yiluphi uhlobo lomdlavuza oluthinta amangqamuzana akho egazi, i-myelodysplastic syndrome (isimo lapho umnkantsha ukhiqiza amaseli egazi angajwayelekile futhi kunengozi yokuthi umdlavuza amaseli egazi angakhula), noma yisiphi esinye isimo esithinta umnkantsha wakho, noma isifo sesibindi. Tshela nodokotela wakho uma ngabe ususwe ubende.
• utshele udokotela wakho uma ukhulelwe noma uhlela ukukhulelwa. Uma ukhulelwa ngenkathi uthola umjovo we-romiplostim, shayela udokotela wakho.
• tshela udokotela wakho uma uncelisa. Akufanele uncelise ibele ngesikhathi sokwelashwa kwakho ngomjovo we-romiplostim.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi uthola umjovo we-romiplostim.
• qhubeka nokugwema imisebenzi engadala ukulimala nokopha ngesikhathi sokwelashwa kwakho ngomjovo we-romiplostim. Umjovo weRomiplostim unikezwa ukunciphisa ubungozi bokuthi uzophuma kakhulu, kepha kusesengozini yokuthi ukuphuma kwegazi kungahle kwenzeke.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Shayela udokotela wakho ngokushesha uma ungakwazi ukugcina i-aphoyintimenti ukuze uthole umthamo womjovo we-romiplostim.

Umjovo we-Romiplostim ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ikhanda
• ubuhlungu obuhlangene noma besisipha
• ubuhlungu ezingalweni, emilenzeni, noma emahlombe
• ukuba ndikindiki, ukushiswa, noma ukuncinza ezingalweni noma emilenzeni
• ubuhlungu besisu
• isilungulela
• ukuhlanza
• isifo sohudo
• ubunzima bokulala noma ukulala
• ukuphuma kwamakhala, ukuminyana, ukukhwehlela, noma ezinye izimpawu ezibandayo
• ubuhlungu bomlomo noma bomphimbo

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

• ukopha
• ukulinyazwa
• ukuvuvukala, ubuhlungu, isisa, imfudumalo noma ubomvu emlenzeni owodwa
• ukuphelelwa umoya
• ekhwehlela igazi
• ukushaya kwenhliziyo okusheshayo
• ukuphefumula okusheshayo
• ubuhlungu lapho uphefumula ngokujulile
• ubuhlungu esifubeni, ezingalweni, emuva, entanyeni, emihlathini, noma esiswini
• aqhume umjuluko obandayo
• isicanucanu
• ubumhlophe
• inkulumo ehamba kancane noma enzima
• isiyezi noma ukuquleka
• ubuthakathaka noma ukuba ndikindiki kwengalo noma komlenze

Umjovo weRomiplostim ungadala ushintsho kumnkantsha wakho wethambo. Lezi zinguquko zingadala ukuthi umnkantsha wakho wenze amangqamuzana egazi ambalwa noma wenze amaseli egazi angajwayelekile. Lezi zinkinga zegazi zingasongela impilo.

Umjovo we-Romiplostim ungadala ukuthi izinga lakho leplatelet likhule kakhulu. Lokhu kungandisa ubungozi bokuthi uzoba negazi, elingasabalala liye emaphashini, noma libangele isifo senhliziyo noma isifo sohlangothi. Udokotela wakho uzoqapha izinga lakho leplatelet ngokucophelela ngenkathi welashwa ngomjovo we-romiplostim.

Ngemuva kokuphela kokwelashwa kwakho ngomjovo we-romiplostim, izinga lakho leplatelet lingahle lehle kunangaphambi kokuba uqale ukwelashwa kwakho ngomjovo we-romiplostim. Lokhu kwandisa ingozi yokuthi uzoba nezinkinga zokopha. Udokotela wakho uzokuqapha ngokucophelela amasonto amabili ngemuva kokuphela kokwelashwa kwakho. Uma unokulimala okungavamile noma ukuphuma kwegazi, tshela udokotela wakho ngokushesha.

Khuluma nodokotela wakho ngezingozi zokuthola umjovo we-romiplostim.

Umjovo we-Romiplostim ungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthola lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho kumjovo we-romiplostim.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Nplate^®