U-Artemether noLumefantrine

-Delile

• Ngaphambi kokuthatha i-artemether ne-lumefantrine,
• I-Artemether ne-lumefantrine kungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi.Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

Inhlanganisela ye-artemether ne-lumefantrine isetshenziselwa ukwelapha izinhlobo ezithile zezifo zikamalaleveva (ukutheleleka okuyingozi okusatshalaliswa omiyane ezingxenyeni ezithile zomhlaba futhi kungadala ukufa). I-Artemether ne-lumefantrine akufanele zisetshenziselwe ukuvikela umalaleveva. U-Artemether no-lumefantrine basesigabeni semithi ebizwa ngama-antimalarials. Isebenza ngokubulala izinto ezibanga umalaleveva.

Inhlanganisela ye-artemether ne-lumefantrine iza njengethebhulethi ezothathwa ngomlomo. Imvamisa kuthathwa kabili ngosuku izinsuku ezi-3 njengokuyalelwa ngudokotela wakho. Njalo thatha i-artemether ne-lumefantrine ngokudla. Uma ungakwazi ukudla, xhumana nodokotela wakho. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-artemether ne-lumefantrine njengoba nje kuqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Uma unenkinga yokugwinya amaphilisi, angagaywa futhi ahlanganiswe nethisipuni elilodwa noma amabili wamanzi esitsheni esihlanzekile. Phuza ingxube ngokushesha. Hlanza ingilazi ngamanzi amaningi bese ugwinya konke okuqukethwe.

Ungahlanza ngemuva nje kokuthatha umuthi. Uma uhlanza kungakapheli ihora elilodwa kuya kwamabili ngemuva kokuthatha i-artemether ne-lumefantrine, kufanele uthathe omunye umthamo ogcwele we-artemether ne-lumefantrine. Uma uhlanza futhi ngemuva kokuthatha umthamo owengeziwe, shayela udokotela wakho.

Kufanele uqale ukuzizwa ungcono phakathi nezinsuku ezimbalwa zokuqala zokwelashwa nge-artemether ne-lumefantrine. Uma izimpawu zakho zingathuthuki noma ziba zimbi kakhulu, shayela udokotela wakho. Phinda ushayele udokotela wakho uma unemfiva, ukugodola, ubuhlungu bemisipha, noma ikhanda ngemuva nje kokuqeda ukwelashwa kwakho. Lokhu kungaba wuphawu lokuthi usatheleleke ngomalaleveva.

Thatha i-artemether ne-lumefantrine uze uqede incwadi kadokotela, noma ngabe uzizwa ungcono. Uma uyeka ukuthatha i-artemether ne-lumefantrine maduzane noma weqe imithamo, ukutheleleka kwakho kungenzeka kungalashwa ngokuphelele futhi izinto eziphilayo zingamelana nama-antimalarials.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-artemether ne-lumefantrine,

• Tshela udokotela wakho kanye nosokhemisi uma uxabana ne-artemether ne-lumefantrine, noma imuphi omunye umuthi, noma iziphi izithako ezikumaphilisi e-artemether kanye ne-lumefantrine. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• utshele udokotela wakho uma uthatha i-carbamazepine (Carbatrol, Epitol, Tegretol); i-phenytoin (iDilantin, Phenytek); i-rifampin (iRifadin, eRifamate, eRifater, eRimactane); noma iSt. Udokotela wakho mhlawumbe uzokutshela ukuthi ungathathi i-artemether ne-lumefantrine uma uthatha eyodwa noma ngaphezulu yale mithi.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma ikuphi kokulandelayo: imishanguzo yokulwa nokudangala okubandakanya i-amitriptyline (Elavil), clomipramine (Anafranil), ne-imipramine (Tofranil); ama-antifungal athile afana ne-fluconazole (Diflucan); i-itraconazole (i-Sporanox) ne-ketoconazole (i-Nizoral); imishanguzo efana ne-mefloquine (Lariam) ne-quinine (i-Qualaquin); i-cisapride (Propulsid) (ayitholakali e-U.S.); ama-antibiotic e-fluoroquinolone njenge-ciprofloxacin (Cipro), i-gatifloxacin (i-Tequin) (ayitholakali e-US), i-gemifloxacin (i-Factive), i-levofloxacin (i-Levaquin), i-lomefloxacin (i-Maxaquin) (ayitholakali e-US), i-moxifloxacin (Avelox) (NegGram), norfloxacin (Noroxin), ofloxacin (Floxin), kanye ne-sparfloxacin (Zagam) (ayitholakali e-US); ama-antibiotic e-macrolide afana ne-clarithromycin (i-Biaxin, ku-PrevPac), i-erythromycin (i-EES, i-Ery-tab, i-Eryc), ne-telithromycin (Ketek); imishanguzo ethile yegciwane lesandulela ngculazi (i-HIV) noma i-immunodeficiency syndrome (i-AIDS) efana ne-atazanavir (Reyataz), i-darunavir (i-Prezista), i-delavirdine (i-Rescriptor), i-efavirenz (i-Sustiva, e-Atripla), i-etravirine (Intelence), i-fosamprenavir (Lexiva) , indinavir (Crixivan), lopinavir (eKaletra), nelfinavir (Viracept), nevirapine (Viramune), rilpivirine (Edurant, eComplera), ritonavir (Norvir, eKaletra), saquinavir (Invirase), nase-tipranavir (Aptivus); imishanguzo yokushaya kwenhliziyo okungajwayelekile kubandakanya i-amiodarone (Cordarone), i-disopyramide (i-Norpace), i-flecainide (iTambocor), i-procainamide (i-Procanbid), i-quinidine, ne-sotalol (i-Betapace, i-Betapace AF, i-Sorine); nemithi ethile yokugula ngengqondo efana ne-pimozide (Orap) ne-ziprasidone (Geodon). Phinda utshele udokotela noma usokhemisi wakho uma uthatha noma uyekile ukuthatha i-halofantrine (Halfan) (ayitholakali e-U.S) enyangeni edlule. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imithi eminingi ingase futhi ihlanganyele ne-artemether ne-lumefantrine, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu.
• Tshela udokotela wakho uma wena noma omunye emndenini wakho enikade isikhathi eside se-QT (inkinga yenhliziyo engajwayelekile engadala ukushaya kwenhliziyo okungajwayelekile, ukuquleka, noma ukufa okungazelelwe); noma uma uke waba nokushaya kwenhliziyo okuhamba kancane, okusheshayo, noma okungafanele; ukuhlaselwa yinhliziyo muva nje; izinga eliphansi le-magnesium noma i-potassium egazini lakho; isifo sezinso, senhliziyo, noma sesibindi.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha i-artemether ne-lumefantrine, shayela udokotela wakho.
• kufanele wazi ukuthi i-artemether ne-lumefantrine kunganciphisa ukusebenza kwezindlela zokuvimbela inzalo zamahomoni (amaphilisi okulawula ukubeletha, amabala, izindandatho, okufakelwa kanye nemijovo). Khuluma nodokotela wakho ngezindlela zokulawula ukubeletha ezizokusebenzela ngenkathi uthatha i-artemether ne-lumefantrine.

Ungaphuzi ijusi yamagilebhisi ngenkathi uthatha lo muthi.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Artemether ne-lumefantrine kungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ikhanda
• isiyezi
• ubuthakathaka
• ubuhlungu bemisipha noma bamalunga
• ukukhathala
• ubunzima bokulala noma ukulala
• ukuhlanza
• ukulahlekelwa isifiso sokudla
• imfiva
• Ukugodola

Eminye imiphumela emibi ingaba mibi.Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukushaya kwenhliziyo okungavamile noma okusheshayo
• ukuquleka
• ukuqubuka
• isifuba
• ukuphefumula kanzima noma ukugwinya
• ukuvuvukala kwezindebe, ulimi, ubuso, noma umphimbo
• ukushaqeka
• kunzima ukukhuluma

I-Artemether ne-lumefantrine kungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Isidakamizwa sakho kungenzeka ukuthi asigcwaliseki. Uma usenezimpawu zokutheleleka ngemuva kokuqeda i-artemether ne-lumefantrine, shayela udokotela wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Coartem^® (equkethe u-Artemether, uLumefantrine)