I-Saxagliptin

-Delile

• Ngaphambi kokuthatha i-saxagliptin,
• Lo muthi ungadala ushintsho kushukela wakho wegazi. Kufanele wazi izimpawu zikashukela wegazi ophansi futhi ophakeme nokuthi yini okufanele uyenze uma unalezi zimpawu.
• I-Saxagliptin ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, yeka ukuthatha i-saxagliptin bese ushayela udokotela wakho ngokushesha:

I-Saxagliptin isetshenziswa kanye nokudla nokuzivocavoca ukwehlisa amazinga kashukela egazini ezigulini ezinesifo sikashukela sohlobo 2 (isimo lapho ushukela wegazi uphakeme kakhulu ngoba umzimba awukhiqizi noma usebenzise i-insulin ngokwejwayelekile). I-Saxagliptin isekilasini lemithi ebizwa nge-dipeptidyl peptidase-4 (DPP-4) inhibitors. Isebenza ngokwandisa inani le-insulin ekhiqizwa ngumzimba ngemuva kokudla lapho ushukela wegazi uphakeme. I-Saxagliptin ayisetshenziselwa ukwelapha uhlobo lwesifo sikashukela sohlobo 1 (isimo lapho umzimba ungakhiqizi khona i-insulin, ngakho-ke, awukwazi ukulawula inani likashukela egazini) noma i-ketoacidosis yesifo sikashukela (isimo esibi esingakhula uma ushukela ophakeme wegazi ungelashwa ).

Ngokuhamba kwesikhathi, abantu abanesifo sikashukela kanye noshukela ophakeme wegazi bangakhula babe nezinkinga ezinkulu noma ezisongela impilo, kufaka phakathi isifo senhliziyo, isifo sohlangothi, izinkinga zezinso, ukulimala kwemizwa nezinkinga zamehlo. Ukuthatha imishanguzo, ukwenza ushintsho endleleni ophila ngayo (isb., Ukudla, ukuzivocavoca umzimba, ukuyeka ukubhema), nokuhlola njalo ushukela wegazi lakho kungasiza ukuphatha isifo sikashukela nokuthuthukisa impilo yakho. Lokhu kwelashwa kunganciphisa namathuba akho okuhlaselwa yisifo senhliziyo, isifo sohlangothi, noma ezinye izinkinga ezihlobene nesifo sikashukela njengokuhluleka kwezinso, ukulimala kwemizwa (okundikindiki, imilenze ebandayo noma izinyawo; ukwehla kwekhono lezocansi kwabesilisa nabesifazane), izinkinga zamehlo, kufaka phakathi izinguquko noma ukulahleka kombono, noma isifo sezinsini. Udokotela wakho nabanye abahlinzeki bezokunakekelwa kwezempilo bazokhuluma nawe ngendlela engcono yokuphatha isifo sikashukela.

I-Saxagliptin iza njengethebhulethi ezothathwa ngomlomo. Imvamisa kuthathwa kanye ngosuku noma ngaphandle kokudla. Thatha i-saxagliptin ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-saxagliptin njengoba nje uqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

I-Saxagliptin ilawula uhlobo lwesifo sikashukela esingu-2 kodwa ayiselaphi. Qhubeka uthathe i-saxagliptin noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-saxagliptin ngaphandle kokukhuluma nodokotela wakho.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa nge-saxagliptin futhi isikhathi ngasinye lapho ugcwalisa umuthi wakho. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) noma iwebhusayithi yomkhiqizi ukuthola i-Medication Guide.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-saxagliptin,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-saxagliptin, noma imuphi omunye umuthi, noma iziphi izithako ezikumaphilisi e-saxagliptin. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: imishanguzo ethize yokubulala izinhlungu efana ne-itraconazole (Onmel, Sporanox) ne-ketoconazole (Nizoral); i-clarithromycin (i-Biaxin); imishanguzo ethile ye-HIV (human immunodeficiency virus) noma i-AIDS (etholwe i-immunodeficiency syndrome) efana ne-atazanavir (Reyataz, e-Evotaz), i-indinavir (i-Crixivan), i-nelfinavir (i-Viracept), i-ritonavir (i-Norvir, e-Kaletra), ne-saquinavir (i-Invirase); i-insulin noma imithi yomlomo yesifo sikashukela njenge-chlorpropamide (i-Diabinese), i-glimepiride (i-Amaryl, e-Duetact), i-glipizide (i-Glucotrol), i-glyburide (i-Diabeta, i-Glynase, e-Glucovance), i-nateglinide (i-Starlix), i-pioglitazone (i-Actos, e-Actoplus Met, e I-Duetact), i-repaglinide (Prandin, ePrandimet), i-rosiglitazone (i-Avandia), i-tolazamide, ne-tolbutamide; nefazodone; kanye ne-telithromycin (ayisatholakali e-U.S .; Ketek). Udokotela wakho kungadingeka ukuthi ushintshe imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• Tshela udokotela wakho uma uphuza noma wake waphuza utshwala obuningi, uma uke waphathwa i-pancreatitis (ukuvuvukala kwamanyikwe), amatshe enyongo, amazinga aphezulu e-triglycerides (okunamafutha) egazini lakho, ukwehluleka kwenhliziyo, i-ketoacidosis yesifo sikashukela, noma isifo sezinso.
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha i-saxagliptin, shayela udokotela wakho.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi uthatha i-saxagliptin.
• khuluma nodokotela wakho ngalokho okufanele ukwenze uma ulimala noma uba nomkhuhlane noma ukutheleleka. Lezi zimo zingathinta ushukela wegazi lakho kanye nenani le-saxagliptin ongayidinga.

Qiniseka ukuthi ulandela zonke izincomo zokuzivocavoca nezokudla ezenziwa ngudokotela wakho noma udokotela odlayo. Kubalulekile ukudla ukudla okunempilo, ukuzivocavoca umzimba njalo, nokunciphisa isisindo uma kunesidingo. Lokhu kuzosiza ukulawula isifo sakho sikashukela futhi kusize i-saxagliptin isebenze kahle.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenzela okulahlekile ngaphandle kokuthi udokotela wakho ekutshela ukuthi kufanele.

Lo muthi ungadala ushintsho kushukela wakho wegazi. Kufanele wazi izimpawu zikashukela wegazi ophansi futhi ophakeme nokuthi yini okufanele uyenze uma unalezi zimpawu.

I-Saxagliptin ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• Umphimbo obuhlungu
• ikhanda
• ubuhlungu obuhlangene

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, yeka ukuthatha i-saxagliptin bese ushayela udokotela wakho ngokushesha:

• ukuqubuka
• isifuba
• ukuxebuka kwesikhumba
• ukulunywa
• ukuvuvukala kobuso, izindebe, ulimi noma umphimbo
• ukuphefumula kanzima noma ukugwinya
• ukushaqeka
• ubuhlungu obuqhubekayo, obuqala phezulu kwesobunxele noma maphakathi nesisu kepha bungasabalala baye emuva
• ukuhlanza
• ukulahlekelwa isifiso sokudla
• ukukhathala ngokweqile
• ukuphefumula, ikakhulukazi lapho ulele phansi
• ukuvuvukala kwezinyawo, amaqakala, noma imilenze
• ukuzuza kwesisindo ngokungazelelwe

I-Saxagliptin ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho mhlawumbe uzo-oda izivivinyo ezithile zaselabhorethri ngaphambi nangesikhathi sokwelashwa kwakho nge-saxagliptin ukuhlola impendulo yomzimba wakho kuyo. Ushukela wegazi kanye ne-hemoglobin eglycosylated (HbA1c) kufanele ihlolwe njalo ukuthola impendulo yakho ku-saxagliptin. Udokotela wakho angakutshela nokuthi ungayihlola kanjani impendulo yakho ku-saxagliptin ngokulinganisa amazinga egazi lakho noma umchamo ekhaya. Landela lezi zinkomba ngokucophelela.

Kufanele njalo ufake isongo lokuhlonza isifo sikashukela ukuze uqiniseke ukuthi uthola ukwelashwa okufanele esimeni esiphuthumayo.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Onglyza^®

• UKombiglyze^® I-XR (equkethe iMetformin, iSaxagliptin)
• Qtern^® (equkethe iDapagliflozin, Saxagliptin)
• Qternmet^® I-XR (equkethe iDapagliflozin, Metformin, Saxagliptin)