Topotecan

-Delile

• Ngaphambi kokuthatha i-topotecan,
• I-Topotecan ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu noma lezo ezibalwe ezigabeni EZIBALULEKILE ZESEXWAYISO noma ZOKUQapha, shayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka:

I-Topotecan ingadala ukwehla kwenani lamaseli egazi enziwe ngomnkantsha wakho. Lokhu kwandisa ubungozi bokuthi uzoba nokutheleleka okungathi sína. Akufanele uthathe i-topotecan uma usuvele unenani eliphansi lamaseli egazi. Udokotela wakho uzo-oda izivivinyo zaselebhu njalo ngaphambi nangesikhathi sokwelashwa kwakho ukubheka ukuthi umzimba wakho unamaseli wegazi anele yini. Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: umphimbo obuhlungu, amakhaza, umkhuhlane, ukukhwehlela, ukushisa noma ukuchama kabuhlungu, noma ezinye izimpawu zokutheleleka; ubuhlungu besisu; ukulimaza noma ukopha okungavamile; ukukhathala ngokweqile; ikhanda; isiyezi; ukudideka; isikhumba esiphaphathekile; ukushaya kwenhliziyo okusheshayo; noma ukuphefumula okuncane.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile ukuze ahlole impendulo yomzimba wakho ku-topotecan.

Khuluma nodokotela wakho ngezingozi zokuthatha i-topotecan.

I-Topotecan isetshenziselwa ukwelapha umdlavuza omncane wamaphaphu wamangqamuzana (uhlobo lomdlavuza oqala emaphashini) owelashwa ngempumelelo ngemithi ehlukile yamakhemikhali kepha ubuyile kungakadluli izinsuku ezingama-45 ngemuva kokuba umthamo wokugcina wemithi yokuqala yamakhemikhali uthathiwe. I-Topotecan isekilasini lemithi ebizwa nge-topoisomerase I inhibitors. Isebenza ngokubulala amangqamuzana omdlavuza.

I-Topotecan iza njenge-capsule ezothathwa ngomlomo. Kungathathwa nokudla noma ngaphandle kokudla. Imvamisa kuthathwa kanye ngosuku izinsuku ezi-5 zilandelana njalo ezinsukwini ezingama-21. Udokotela wakho uzonquma ukuthi kufanele uwuphindaphinde kangaki lo mjikelezo. Thatha i-topotecan ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-topotecan njengoba nje kuqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Gwinya wonke amaphilisi ngamanzi; ungazivuli, uzihlafune noma uzichoboze.

Amaphilisi weTopotecan afika ngamandla amabili ahlukene. Udokotela wakho angafuna ukuthi uthathe inhlanganisela yamandla womabili wamaphilisi okwenza umthamo wakho ogcwele. Qiniseka ukuthi uyazi ukuthi uhlobo ngalunye lwe-capsule lubukeka kanjani nokuthi uzothatha kangaki ngalunye. Buza udokotela wakho noma usokhemisi uma unemibuzo.

Uma kukhona noma yimaphi amaphilisi aphukile noma avuzayo, ungawathinti ngezandla zakho. Lahla ngokucophelela amaphilisi aphukile ngaphandle kokuwathinta ngqo bese ugeza izandla zakho kahle ngensipho namanzi. Uma okuqukethwe kwe-capsule kuthinta isikhumba sakho, geza indawo kahle ngensipho namanzi khona lapho. Uma ngabe kukhona okuqukethwe okuyi-capsule emehlweni akho, geza amehlo akho ngaso leso sikhathi ngamanzi ageleza kamnandi okungenani imizuzu eyi-15. Shayela udokotela wakho uma kukhona ukusabela kwesikhumba noma uma umuthi ungena emehlweni akho.

Ungahlanza ngemuva kokuthatha umuthi. Uma lokhu kwenzeka, yazisa udokotela wakho ngokushesha. Ungathathi omunye umthamo we-topotecan ngosuku olufanayo.

Udokotela wakho angadinga ukubambezela ukwelashwa kwakho noma alungise umthamo wakho uma uhlangabezana nemiphumela ethile emibi. Qiniseka ukuthi utshela udokotela wakho ukuthi uzizwa kanjani ngenkathi ukwelashwa nge-topotecan.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-topotecan,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-topotecan, noma imiphi eminye imithi, noma yiziphi izithako kuma-capsule we-topotecan. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: i-cyclosporine (Gengraf, Neoral, Sandimmune); ketoconazole (Nizoral); i-ritonavir (iNorvir, eKaletra); noma i-saquinavir (i-Fortovase, i-Invirase). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• Tshela udokotela wakho uma uke waba nesifo sezinso noma wake waba naso.
• utshele udokotela wakho uma ukhulelwe noma uhlela ukukhulelwa. Akufanele ukhulelwe ngenkathi uthatha i-topotecan. Khuluma nodokotela wakho ngezindlela zokulawula ukubeletha ongazisebenzisa ngesikhathi sokwelashwa kwakho. Uma ukhulelwa ngenkathi uthatha i-topotecan, shayela udokotela wakho ngokushesha. I-Topotecan ingalimaza umbungu.
• tshela udokotela wakho uma uncelisa. Akufanele uncelise ibele ngenkathi uthatha i-topotecan.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi uthatha i-topotecan.
• kufanele wazi ukuthi i-topotecan ingakwenza ukozele, ukhathele noma ube buthakathaka. Ungashayeli imoto, sebenzisa amathuluzi asindayo, noma usebenzise imishini uze wazi ukuthi lo muthi ukuthinta kanjani.
• kufanele wazi ukuthi i-topotecan ingadala isifo sohudo esibi esingadinga ukwelashwa esibhedlela. Khuluma nodokotela wakho mayelana nokuthi ungasinqanda kanjani futhi uselaphe kanjani isifo sohudo. Shayela udokotela wakho ngokushesha uma unezinye zalezi zimpawu ezilandelayo: isifo sohudo esinomkhuhlane, isifo sohudo izikhathi ezintathu noma ngaphezulu ngosuku, noma isifo sohudo esibuhlungu besisu noma amajaqamba.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Yeqa umthamo ophuthelwe bese uqhubeka nesimiso sakho sokulinganisa esivamile. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile. Yazisa udokotela wakho uma uphuthelwa umthamo.

I-Topotecan ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isicanucanu
• ukuhlanza
• isifo sohudo
• ukulahlekelwa isifiso sokudla
• ukulahleka kwezinwele

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu noma lezo ezibalwe ezigabeni EZIBALULEKILE ZESEXWAYISO noma ZOKUQapha, shayela udokotela wakho ngokushesha:

• isifuba
• ukuqubuka
• ukulunywa
• ukushaqeka
• ukuphefumula kanzima noma ukugwinya

I-Topotecan ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Yigcine esiqandisini bese uyivikela ekukhanyeni.

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka:

• umphimbo obuhlungu, amakhaza, umkhuhlane, ukukhwehlela, ukushisa noma ukuchama kabuhlungu, noma ezinye izimpawu zokutheleleka
• ukulimaza noma ukopha okungavamile
• ukukhathala ngokweqile
• ikhanda
• isiyezi
• ukudideka
• isikhumba esiphaphathekile
• ukushaya kwenhliziyo okusheshayo
• ukuphelelwa umoya

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Hycamtin^®