I-Dalfampridine

-Delile

• Ngaphambi kokuthatha i-dalfampridine,
• IDalfampridine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho noma uthole ukwelashwa okuphuthumayo ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

I-Dalfampridine isetshenziselwa ukuthuthukisa ukuhamba kubantu abane-multiple sclerosis (MS; isifo lapho izinzwa zingasebenzi kahle futhi zingadala ubuthakathaka, ukuba ndikindiki, ukulahleka kokuhlangana kwemisipha, nezinkinga ngombono, ukukhuluma, nokulawula isinye). IDalfampridine ingasetshenziswa yodwa noma ngeminye imithi elawula izimpawu ze-MS. IDalfampridine isekilasini lemithi ebizwa nge-potassium channel blockers. Isebenza ngokuqinisa amasiginali athunyelwe ubuchopho ngezinzwa ezonakaliswe yi-MS.

IDalfampridine iza njengethebhulethi ekhishwa isikhathi eside ezothathwa ngomlomo. Imvamisa kuthathwa ngokudla noma ngaphandle kokudla kabili ngosuku. Beka isikhala imithamo yakho ukuze uthathe umthamo owodwa cishe njalo emahoreni ayi-12, bese uthatha i-dalfampridine ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-dalfampridine njengoba nje kuqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Gwinya wonke amaphilisi; ungawahlukanisi, ungawahlafune, ungawaqedi noma uwaqede.

IDalfampridine ayitholakali ezikhemisi. Ungathola kuphela i-dalfampridine ngeposi kusuka ekhemisi ekhethekile. Buza udokotela wakho uma unemibuzo mayelana nokuthola imithi yakho.

IDalfampridine ingasiza ekuthuthukiseni ukuhamba kwakho kuphela uma nje uqhubeka nokukuthatha. Kungathatha amasonto ayisithupha noma ngaphezulu ngaphambi kokuba uzwe ngokugcwele nge-dalfampridine. Qhubeka uthathe i-dalfampridine noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-dalfampridine ngaphandle kokukhuluma nodokotela wakho.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa nge-dalfampridine futhi isikhathi ngasinye lapho ugcwalisa umuthi wakho. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) ukuthola uMhlahlandlela Wezokwelapha.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-dalfampridine,

• Tshela udokotela kanye nosokhemisi wakho uma une-allergies ku-dalfampridine, 4-aminopyridine (4-AP, fampridine) ebilungiswa ngusokhemisi wakho, noma imuphi omunye umuthi, noma iziphi izithako ezikumaphilisi e-dalfampridine. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qinisekisa ukusho noma yiluphi olunye uhlobo lwe-4-aminopyridine (4-AP, fampridine) esilungiswe ngusokhemisi wakho. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• utshele udokotela wakho ukuthi wake waquleka yini futhi unesifo sezinso. Udokotela wakho mhlawumbe uzokutshela ukuthi ungathathi i-dalfampridine.
• Tshela udokotela wakho uma wake waba ne-electroencephalogram engajwayelekile (i-EEG, isivivinyo esilinganisa ukusebenza kukagesi ebuchosheni).
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha i-dalfampridine, shayela udokotela wakho.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Yeqa umthamo ophuthelwe bese uqhubeka nesimiso sakho sokulinganisa esivamile. Ungathathi imithamo engaphezu kwemibili ye-dalfampridine esikhathini samahora angama-24 futhi ungathathi umthamo ophindwe kabili ukwenzela okulahlekile.

IDalfampridine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ubunzima bokulala noma ukulala
• isiyezi
• ikhanda
• isicanucanu
• isilungulela
• ukuqunjelwa
• ubuthakathaka
• ukuhlungu obusemhlane
• ubunzima ngokulinganisela
• ukwanda kwezimpawu ze-sclerosis eziningi
• ukushisa, ukudlikizela noma ukulunywa kwesikhumba
• ubuhlungu noma ukucasuka emakhaleni noma emphinjeni

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho noma uthole ukwelashwa okuphuthumayo ngokushesha:

• isithuthwane
• ukuchama okubuhlungu, okunzima, noma okuvamile
• umkhuhlane noma amakhaza
• ubuhlungu emuva, ohlangothini, noma esiswini

IDalfampridine ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• ukudideka
• isithuthwane
• ukuzamazama okungalawuleki kwengxenye yomzimba wakho
• ukujuluka
• ukulahleka kwememori
• izinkinga zokukhuluma
• ubuthakathaka

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ku-dalfampridine.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Ampyra^®

• I-4-aminopyridine
• I-4-AP
• fampridine