I-Diclofenac Topical (i-actinic keratosis)

-Delile

• Ngaphambi kokusebenzisa ijeli ye-diclofenac,
• Ijeli le-Diclofenac lingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu shayela udokotela wakho ngokushesha:

Abantu abasebenzisa izidakamizwa ezingezona ukuvuvukala (ama-NSAID) (ngaphandle kwe-aspirin) njenge-topical diclofenac (i-Solaraze) bangaba nengozi enkulu yokuhlaselwa yisifo senhliziyo noma isifo sohlangothi kunabantu abangayisebenzisi le mithi. Le micimbi ingenzeka ngaphandle kwesixwayiso futhi ingadala ukufa. Le ngozi ingase ibe phezulu kubantu abasebenzisa ama-NSAID isikhathi eside. Ungathathi i-NSAID efana ne-diclofenac yama-topical uma usanda kuhlaselwa yisifo senhliziyo, ngaphandle kokuthi uqondiswe ngudokotela wakho. Tshela udokotela wakho uma wena noma omunye emndenini wakho enesifo senhliziyo, isifo senhliziyo, noma isifo sohlangothi; uma ubhema; futhi uma uke waba noma uke waba ne-cholesterol ephezulu, umfutho wegazi ophakeme, noma isifo sikashukela. Thola usizo lwezempilo oluphuthumayo ngokushesha uma uhlangabezana nalezi zimpawu ezilandelayo: ubuhlungu besifuba, ukuphefumula okuncane, ubuthakathaka engxenyeni eyodwa noma ohlangothini lomzimba wakho, noma inkulumo engacacile.

Uma uzobe ubhekene nomthambo we-coronary bypass graft (CABG; uhlobo lokuhlinzwa kwenhliziyo), akufanele usebenzise i-topical diclofenac (Solaraze) ngaphambi noma ngemuva kokuhlinzwa.

Ama-NSAID anjenge-topical diclofenac (Solaraze) angadala ukuvuvukala, izilonda, ukopha, noma izimbobo esiswini noma emathunjini. Lezi zinkinga zingakhula nganoma yisiphi isikhathi ngesikhathi sokwelashwa, zingenzeka ngaphandle kwezimpawu zokuxwayisa, futhi zingadala nokufa. Ingozi ingaba phezulu kubantu abasebenzisa ama-NSAID isikhathi eside, sebekhulile ngeminyaka, banempilo ebuthaka, bayabhema, noma baphuza utshwala ngenkathi besebenzisa i-diclofenac eyisihloko. Tshela udokotela wakho uma unalezi zinto eziyingozi futhi uma uke waba nezilonda noma wopha esiswini noma emathunjini, noma ezinye izifo zokopha. Tshela udokotela wakho uma uthatha noma imuphi wale mithi elandelayo: ama-anticoagulants (’ama-thinner egazi’) afana ne-warfarin (Coumadin, Jantoven); i-aspirin; amanye ama-NSAID afana ne-ibuprofen (Advil, Motrin) noma naproxen (Aleve, Naprosyn); i-steroids yomlomo efana ne-dexamethasone, i-methylprednisolone (i-Medrol), ne-prednisone (i-Rayos); i-serotonin reuptake inhibitors (SSRIs) ekhethiwe njenge-citalopram (Celexa), i-fluoxetine (i-Prozac, i-Sarafem, i-Selfemra, ku-Symbyax), i-fluvoxamine (i-Luvox), i-paroxetine (i-Brisdelle, i-Paxil, i-Pexeva) ne-sertraline (i-Zoloft); noma i-serotonin norepinephrine reuptake inhibitors (SNRIs) efana ne-desvenlafaxine (Khedezla, Pristiq), duloxetine (Cymbalta), ne-venlafaxine (Effexor XR). Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo, yeka ukusebenzisa i-diclofenac eyisihloko bese ufonela udokotela wakho: ubuhlungu besisu, isilungulela, ukuhlanza into enegazi noma ebukeka njengezizathu zekhofi, igazi esitokisini, noma izitulo ezimnyama nezokulinda.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzoqapha izimpawu zakho ngokucophelela futhi mhlawumbe uzothatha umfutho wegazi lakho futhi a-oda izivivinyo ezithile ukuhlola impendulo yomzimba wakho ku-diclofenac yama-topical (Solaraze). Qiniseka ukuthi utshela udokotela wakho ukuthi uzizwa kanjani ukuze udokotela akwazi ukukubeka inani elifanele lemithi yokwelapha isimo sakho ngengozi ephansi kakhulu yemiphumela emibi kakhulu.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa nge-diclofenac ewuchungechunge futhi isikhathi ngasinye ugcwalisa umuthi wakho. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) ukuthola uMhlahlandlela Wezokwelapha.

I-Diclofenac topical gel (Solaraze) isetshenziselwa ukwelapha i-actinic keratosis (isicaba, isikhumba esikhulayo esikhunjeni esidalwa wukuchayeka kakhulu elangeni). I-Diclofenac isekilasini lemithi ebizwa ngama-nonsteroidal anti-inflammatory drug (NSAIDs). Indlela i-diclofenac gel esebenza ngayo ukwelapha i-actinic keratosis ayaziwa.

I-Diclofenac iyatholakala futhi njengoketshezi (i-Pennsaid) ne-gel (i-Voltaren) esetshenziswa esikhumbeni ukwelapha ubuhlungu be-arthritis. Le monograph inika kuphela imininingwane nge-diclofenac gel (Solaraze) ye-actinic keratosis. Uma usebenzisa omunye wemikhiqizo ye-osteoarthritis, funda i-monograph enesihloko esithi diclofenac topical (ubuhlungu be-osteoarthritis).

I-diclofenac eyisihloko ye-actinic keratosis iza njengejeli (iSolaraze) ukufaka esikhumbeni. Isetshenziswa endaweni ethintekile izikhathi ezimbili ngosuku izinsuku ezingama-60 kuya kwezingama-90. Faka ijeli le-diclofenac ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Sebenzisa i-diclofenac gel njengoba nje kuqondisiwe. Ungayisebenzisi ngaphezulu noma ngaphansi kwayo noma uyisebenzise kaningi kunokuyalelwa ngudokotela wakho.

Ungafaki i-diclofenac gel ukuvula amanxeba esikhumba, ukutheleleka, noma isikhumba esibomvu, esine-scaly, noma esikhulayo.

Ijeli le-Diclofenac lisetshenziselwa kuphela esikhumbeni. Qaphela ukuthi ungatholi umuthi emehlweni akho.

Geza izandla zakho ngaphambi kokufaka ijeli ye-diclofenac. Bese usebenzisa iminwe yakho ukushelela kahle ijeli endaweni ngayinye ethintekile. Sebenzisa ijeli eyanele ukumboza izindawo ngokuphelele. Uma usuqedile ukufaka ijeli, geza izandla zakho futhi. Qaphela ukuthi ungathinti amehlo noma amakhala ngaphambi kokugeza izandla.

Isimo sakho singaqala ukuba ngcono ngemuva kwezinsuku ezingama-30 sokwelashwa, kepha kungathatha izinsuku ezingama-30 ngemuva kokuphela kokwelashwa ngaphambi kokuthi ubone ukuphulukiswa okuphelele kwendawo ethintekile noma inzuzo ephelele yejeli ye-diclofenac. Qhubeka nokusebenzisa ijeli ye-diclofenac noma ngabe isimo sakho sesiqale ukuba ngcono. Ungayeki ukusebenzisa umuthi ngaphandle kokukhuluma nodokotela wakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokusebenzisa ijeli ye-diclofenac,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-diclofenac (eCambia, Flector, Voltaren, Pennsaid, Zipsor, Zorvolex, e-Arthrotec), i-aspirin, noma amanye ama-NSAID; noma imiphi eminye imithi; noma yiziphi izithako ezisejelini le-diclofenac. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma ikuphi kokulandelayo: i-angiotensin-converting enzyme (ACE) inhibitors efana ne-benazepril (Lotensin, eLotrel), i-captopril, i-enalapril (i-Vasotec, e-Vaseretic), i-fosinopril, i-lisinopril (i-Prinivil, i-Zestril, i-Prinzide ne-Zestoretic) , moexipril (Univasc, in Uniretic), perindopril (Aceon, in Prestalia), quinapril (Accupril, in Quinaretic), ramipril (Altace), ne-trandolapril (Mavik, eTarka); ama-angiotensin receptor blockers anjenge-candesartan (Atacand, e-Atacand HCT), eprosartan (Teveten), irbesartan (Avapro, e-Avalide), losartan (Cozaar, e-Hyzaar), olmesartan (Benicar, e-Azor, e-Benicar HCT, e-Tribenzor), i-telmisartan (Micardis, e-Micardis HCT, e-Twynsta), ne-valsartan (e-Exforge HCT); i-aspirin noma eminye imishanguzo yokulwa nokuvuvukala (ama-NSAID) njenge-ibuprofen (Advil, Motrin) ne-naproxen (Aleve, Naprosyn); isisu (‘amaphilisi amanzi’); neminye imithi efakwa esikhunjeni. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• khuluma nodokotela wakho ngaphambi kokufaka i-sunscreen noma izimonyo esikhumbeni eselashwa nge-gel ye-diclofenac.
• Tshela udokotela wakho uma uke waba ne-asthma, ikakhulukazi uma unezimpumputhe ezivame kakhulu noma ezigijimayo noma ama-nasal polyps (ukuvuvukala kwendwangu yekhala), ukuhluleka kwenhliziyo, noma isifo sezinso noma sesibindi.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa; noma ukuncelisa ibele. I-Diclofenac ingalimaza umbungu futhi idale izinkinga ngokulethwa uma isetshenziswa cishe amasonto angama-20 noma kamuva ngesikhathi sokukhulelwa. Ungasebenzisi i-diclofenac gel ezungeze noma ngemuva kwamasonto angama-20 ukhulelwe, ngaphandle kwalapho utshelwa ngudokotela wakho ukuthi wenze njalo. Uma ukhulelwa ngenkathi usebenzisa i-diclofenac gel, shayela udokotela wakho.
• hlela ukugwema ukuvezwa yilanga langempela nelokufakelwa (amalambu elanga) nokugqoka izingubo zokuzivikela nezibuko zelanga ngesikhathi sokwelashwa kwakho ngejeli ye-diclofenac.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Sebenzisa umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungafaki i-gel eyengeziwe ukwenzela umthamo ophuthelwe.

Ijeli le-Diclofenac lingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ubomvu, ukulunywa, ukuxebuka noma isikhumba esomile, ukucasuka, ukuvuvukala, noma ukuqhuma endaweni lapho usebenzise khona umuthi
• ubuhlungu, ukuvutha, ukuba ndikindiki, noma ukudlikiza kwesikhumba esiphathwayo
• ubuhlungu bemisipha, obuhlangene noma obuya emuva
• ikhanda

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu shayela udokotela wakho ngokushesha:

• isifuba
• ukuqubuka
• ukulunywa
• ubunzima bokugwinya
• ukushaqeka
• ukuzuza kwesisindo okungaqondakali
• ukuphefumula okuncane noma ukuphefumula kanzima
• ukuvuvukala esiswini, emaqakaleni, ezinyaweni, noma emilenzeni

Ijeli le-Diclofenac lingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi usebenzisa lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Yigcine ekamelweni lokushisa kude nokukhanya, ukushisa okweqile, nomswakama (hhayi endlini yangasese). Ungavumeli i-gel ye-diclofenac iqhwa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma othile egwinya i-diclofenac gel, shayela isikhungo sakho sendawo sokulawula ubuthi ku-1-800-222-1222. Uma isisulu siwile noma singaphefumuli, shayela abezimo eziphuthumayo zendawo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho.

Ungavumeli omunye umuntu asebenzise imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Solaraze^® Ijeli