Inaliti ye-Belatacept

-Delile

• Ngaphambi kokuthola umjovo we-belatacept,
• Umjovo we-Belatacept ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

Ukuthola umjovo we-belatacept kungakhuphula ubungozi bokuthi uzoba ne-post-transplant lymphoproliferative disorder (PTLD, isimo esibi ngokukhula okusheshayo kwamaseli athile amhlophe egazi, angahle abe uhlobo lomdlavuza). Ingozi yokuthuthukisa i-PTLD ingaphezulu uma ungazange uvezwe ngegciwane le-Epstein-Barr (i-EBV, igciwane elibangela i-mononucleosis noma i- '' mono '') noma uma une-cytomegalovirus infection (CMV) noma uthole ezinye izindlela zokwelapha eziphansi Ama-lymphocyte T (uhlobo lweseli elimhlophe) egazini lakho. Udokotela wakho uzo-oda izivivinyo ezithile zebhu ukuze ahlole lezi zimo ngaphambi kokuthi uqale ukwelashwa ngalo muthi. Uma ungazange uvezwe ngegciwane le-Epstein-Barr, udokotela wakho cishe ngeke akunikeze umjovo we-belatacept. Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo ngemuva kokuthola umjovo we-belatacept, shayela udokotela wakho ngokushesha: ukudideka, ukucabanga kanzima, izinkinga ngememori, ukuguquka kwemizwelo noma indlela oziphatha ngayo, ukushintsha endleleni ohamba ngayo noma okhuluma ngayo, ukwehla kwamandla noma ubuthakathaka uhlangothi lomzimba wakho, noma izinguquko kumbono.

Ukuthola umjovo we-belatacept kungakhuphula nobungozi bokuthola umdlavuza, kufaka phakathi umdlavuza wesikhumba, kanye nokutheleleka okungathi sína, kubandakanya isifo sofuba (i-TB, ukutheleleka kwamaphaphu kwebhaktheriya) kanye ne-leukoencephalopathy eqhubekayo ye-multifocal (PML, isifo esingajwayelekile, esibi kakhulu sobuchopho). Uma uhlangabezana nalezi zimpawu ezilandelayo ngemuva kokuthola i-belatacept, shayela udokotela wakho khona manjalo: isikhumba esisha noma iqhubu, noma ushintsho kusayizi noma kumbala wemvukuzane, umkhuhlane, umphimbo obuhlungu, ukugodola, ukukhwehlela nezinye izimpawu ukutheleleka; ukujuluka ebusuku; ukukhathala okungapheli; ukuncipha komzimba; ama-lymph node avuvukile; izimpawu ezinjengomkhuhlane; ubuhlungu endaweni yesisu; ukuhlanza; isifo sohudo; ubumnene phezu kwendawo yezinso ezifakiwe; ukuchama kaningi noma okubuhlungu; igazi emchameni; ubumpofu; ukwanda kobuthakathaka; izinguquko zobuntu; noma izinguquko embonweni nasenkulumweni.

Umjovo we-Belatacept kufanele unikezwe kuphela esikhungweni sezokwelapha ngaphansi kweso lodokotela onolwazi ekwelapheni abantu abaye bafakelwa izinso nasekunikeni imishanguzo eyehlisa ukusebenza kwamasosha omzimba.

Umjovo we-Belatacept ungadala ukwenqatshwa kwesibindi esisha noma ukufa kubantu abaye bafakelwa isibindi. Lo muthi akufanele unikezwe ukuvimbela ukwenqatshwa kokufakelwa kwesibindi.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa ngomjovo we-belatacept futhi isikhathi ngasinye lapho ugcwalisa umuthi wakho. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) noma iwebhusayithi yomkhiqizi ukuthola i-Medication Guide.

Khuluma nodokotela wakho ngezingozi zokuthola ukwelashwa nge-belatacept.

Umjovo we-Belatacept usetshenziswa ngokuhlangana neminye imishanguzo ukuvimbela ukwenqatshwa (ukuhlaselwa kwesitho esithwelwe kabusha amasosha omzimba womuntu othola isitho) sokufakelwa kwezinso. Umjovo we-Belatacept usesigabeni semithi ebizwa ngama-immunosuppressants. Isebenza ngokunciphisa ukusebenza kwamasosha omzimba ukuyivimba ekuhlaseleni izinso ezifakiwe.

Umjovo we-Belatacept uza njengesisombululo (uketshezi) esizofakwa ngaphezu kwemizuzu engama-30 emthanjeni, imvamisa udokotela noma umhlengikazi esibhedlela noma esikhungweni sezokwelapha. Imvamisa inikezwa ngosuku lokufakelwa kabusha, ezinsukwini eziyi-5 ngemuva kokufakelwa, ekupheleni kwamasonto 2 no-4, bese kanye kanye emavikini amane.

Udokotela wakho uzokuqapha ngokucophelela. Khuluma nodokotela wakho mayelana nokuthi uzizwa kanjani ngesikhathi sokwelashwa kwakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola umjovo we-belatacept,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-belatacept noma eminye imithi, noma yiziphi izithako zomjovo we-belatacept. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• utshele udokotela wakho uma unezimo ezithile zezokwelapha.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha umjovo we-belatacept, shayela udokotela wakho.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi uthola umjovo we-belatacept.
• hlela ukugwema ukuvezwa yilanga ngokungadingekile noma isikhathi eside, imibhede yokushuka, namalambu elanga I-Belatacept ingenza isikhumba sakho sizwele ekukhanyeni kwelanga. Gqoka izingubo zokuzivikela, izibuko zelanga, nesikhumba esivikela ilanga esinezinto zokuvikela (SPF) lapho kufanele ube selangeni ngesikhathi sokwelashwa kwakho.
• ungenayo imigomo ngaphandle kokukhuluma nodokotela wakho.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Uma uphuthelwa isikhathi sokuthola umjovo we-belatacept, shayela udokotela wakho ngokushesha okukhulu.

Umjovo we-Belatacept ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ikhanda
• ukukhathala ngokweqile
• isikhumba esiphaphathekile
• ukushaya kwenhliziyo okusheshayo
• ubuthakathaka
• ukuvuvukala kwezandla, izinyawo, amaqakala, noma imilenze engezansi
• ukuqunjelwa

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:

• ukuphelelwa umoya

Umjovo we-Belatacept ungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthola lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• ukudideka
• ubunzima bokukhumbula
• shintsha esimeni, ebuntwini, noma ekuziphatheni
• ubulukhuni
• shintsha ekuhambeni noma ekukhulumeni
• ukuncipha kwamandla noma ubuthakathaka ngakolunye uhlangothi lomzimba
• shintsha embonweni noma enkulumweni

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Nulojix^®