Inaliti ye-Melphalan

-Delile

• Ngaphambi kokuthola umjovo we-melphalan,
• Umjovo weMelphalan ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SEXWAYISO, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

Umjovo weMelphalan kufanele unikezwe kuphela ngaphansi kokuqondisa kukadokotela onolwazi ekusetshenzisweni kwemithi yokwelapha ngamakhemikhali.

IMelphalan ingadala ukwehla okukhulu kwenani lamaseli egazi emnkantsheni wakho wethambo. Lokhu kungadala izimpawu ezithile futhi kungakhuphula ubungozi bokuthi uzoba nokutheleleka okungathi sína noma ukopha. Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: umkhuhlane, umphimbo obuhlungu, ukukhwehlela okuqhubekayo nokuminyana, noma ezinye izimpawu zokutheleleka; ukopha okungavamile noma ukulimaza; ezinegazi noma ezimnyama, izitulo zokulinda; ukuhlanza kwegazi; noma ukugabha igazi noma okokusundu okufana nezindawo zekhofi.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo zaselebhu njalo ngaphambi nangesikhathi sokwelashwa kwakho ukubona ukuthi amaseli akho egazi ayathinteka yini yilo muthi.

IMelphalan ingakhuphula ubungozi bokuthi uzoba neminye imidlavuza. Khuluma nodokotela wakho ngezingozi zokuthatha i-melphalan.

Umjovo weMelphalan usetshenziselwa ukwelapha i-myeloma eminingi (uhlobo lomdlavuza womnkantsha wethambo). Umjovo weMelphalan kufanele usetshenziselwe ukwelapha abantu abangakwazi ukuthatha i-melphalan ngomlomo. UMelphalan usesigabeni semithi ebizwa ngama-alkylating agents. Isebenza ngokumisa noma ukunciphisa ukukhula kwamangqamuzana omdlavuza emzimbeni wakho.

Umjovo weMelphalan uza njengempuphu ezoxubaniswa noketshezi oluzofakwa kancane ngaphakathi (emthanjeni) ngaphezu kwemizuzu eyi-15 kuye kwengama-30 ngudokotela noma umhlengikazi esikhungweni sezokwelapha. Imvamisa inikezwa kanye njalo emavikini ama-2 ngemithamo emi-4 nangemva kwalokho, kanye njalo emavikini amane. Ubude bokwelashwa buxhomeke ekutheni umzimba wakho uphendula kanjani ekwelashweni.

Udokotela wakho angadinga ukubambezela ukwelashwa kwakho noma alungise umthamo wakho uma uhlangabezana nemiphumela ethile emibi. Kubalulekile ukuthi utshele udokotela wakho ukuthi uzizwa kanjani ngesikhathi sokwelashwa kwakho nge-melphalan

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola umjovo we-melphalan,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-melphalan, noma imiphi eminye imithi, noma yiziphi izithako zomjovo we-melphalan. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha.Qiniseka ukuthi usho noma yikuphi okulandelayo: i-carmustine (BICNU, BCNU), i-cisplatin (i-Platinol AQ), i-cyclosporine (i-Sandimmune, i-Gengraf, i-Neoral), noma i-interferon alfa (i-Intron A, i-Infergen, i-Alferon N).
• Tshela udokotela wakho uma ngabe uke wathatha i-melphalan phambilini, kepha umdlavuza wakho awuphendulanga emithini. Udokotela wakho cishe ngeke afune ukuthi uthole umjovo we-melphalan.
• tshela udokotela wakho uma ngabe uthole ukwelashwa ngemisebe noma enye i-chemotherapy muva nje noma uma uke waba nesifo sezinso noma wake waba naso.
• kufanele wazi ukuthi i-melphalan ingaphazamisa umjikelezo ojwayelekile wokuya esikhathini (isikhathi) kwabesifazane futhi ingamisa okwesikhashana noma unomphela ukukhiqizwa kwesidoda emadodeni. I-Melphalan ingadala ukungazali (ubunzima bokukhulelwa); noma kunjalo, akufanele ucabange ukuthi awukwazi ukukhulelwa noma ukuthi awukwazi ukukhulelisa omunye umuntu. Abesifazane abakhulelwe noma abancelisayo kufanele batshele odokotela babo ngaphambi kokuba baqale ukusebenzisa lo muthi. Akufanele uhlele ukuba nezingane noma ukuncelisa ibele ngenkathi uthola i-chemotherapy noma isikhashana ngemuva kokwelashwa. (Khuluma nodokotela wakho ukuthola eminye imininingwane.) Sebenzisa indlela ethembekile yokulawula inzalo ukuvimbela ukukhulelwa. IMelphalan ingalimaza umbungu.
• ungenayo imigomo ngaphandle kokukhuluma nodokotela wakho.

Umjovo weMelphalan ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isicanucanu
• ukuhlanza
• ukulahlekelwa isifiso sokudla noma isisindo
• isifo sohudo
• izilonda emlonyeni nasemphinjeni
• isikhathi sokuya esikhathini (emantombazaneni nakwabesifazane)
• ukulahleka kwezinwele
• umuzwa ofudumele kanye / noma wokushosholoza

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SEXWAYISO, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ubuhlungu, ukulunywa, ububomvu, ukuvuvukala, amabhamuza, noma izilonda endaweni lapho kwafakwa khona umuthi
• ukuqubuka
• isifuba
• ukulunywa
• ukuphefumula kanzima noma ukugwinya
• isikhumba esiphaphathekile
• ukukhathala okungajwayelekile noma ubuthakathaka
• ukuquleka
• ukushaya kwenhliziyo okusheshayo, okungajwayelekile, noma okushaya ngamandla
• ubuhlungu besifuba
• ukuphuzi kwesikhumba noma kwamehlo
• ubuhlungu engxenyeni engenhla kwesokudla yesisu
• umchamo onombala omnyama
• izigaxa noma uquqaba olungavamile

Umjovo weMelphalan ungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• isicanucanu esinzima
• ukuhlanza okukhulu
• isifo sohudo esibi
• izilonda emlonyeni nasemphinjeni
• okumnyama, okulindile, noma okokuchitha okunegazi
• ukuhlanza okunegazi noma okokuhlanza okubukeka njengezizathu zekhofi
• ukulimaza noma ukopha okungavamile
• isithuthwane
• kwehle ukwazi
• ukulahleka kwekhono lokuhambisa imisipha nokuzwa ingxenye yomzimba

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Alkeran^® Ukujova

• Isinaphi sePhenylalanine