Inaliti ye-Pertuzumab

-Delile

• Ngaphambi kokuthola umjovo we-pertuzumab,
• Umjovo wePertuzumab ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu noma lezo ezisohlwini LWEZEXWAYISO EZIBALULEKILE nokuthi ZIYINI izingxenye, shayela udokotela wakho ngokushesha:

Umjovo wePertuzumab ungadala izinkinga zenhliziyo ezinkulu noma ezisongela impilo, kufaka phakathi ukwehluleka kwenhliziyo. Tshela udokotela wakho uma ngabe usanda kuhlaselwa yinhliziyo noma uke waba nomfutho wegazi ophakeme, ukwehluleka kwenhliziyo, isigqi senhliziyo esingajwayelekile, noma isifo senhliziyo. Udokotela wakho uzohlola ukusebenza kwenhliziyo yakho ngaphambi nangesikhathi sokwelashwa kwakho. Uma uhlangabezana nalezi zimpawu ezilandelayo, tshela udokotela wakho ngokushesha: ukuphefumula, ukukhwehlela, ukuvuvukala kwamaqakala, imilenze, noma ubuso, ukushaya kwenhliziyo okusheshayo, ukuzuza kwesisindo okungazelelwe, isiyezi, noma ukulahlekelwa ukwazi.

Umjovo wePertuzumab akufanele usetshenziswe ngabesifazane abakhulelwe noma abangakhulelwa. Kukhona ingozi yokuthi i-pertuzumab izodala ukulahleka kokukhulelwa noma izodala ukuthi ingane izalwe inokukhubazeka kokuzalwa (izinkinga zomzimba ezikhona lapho kuzalwa). Tshela udokotela wakho uma ukhulelwe noma uhlela ukukhulelwa. Uzodinga ukuhlolwa kokukhulelwa ngaphambi kokuthola le mithi. Kufanele usebenzise ukulawulwa kokubeletha okusebenzayo ngenkathi welashwa ngomjovo we-pertuzumab nezinyanga eziyi-7 ngemuva komthamo wakho wokugcina. Khuluma nodokotela wakho ngezindlela zokulawula ukubeletha ezizokusebenzela. Uma ukhulelwa ngesikhathi sokwelashwa ngomjovo we-pertuzumab, noma ucabanga ukuthi kungenzeka ukhulelwe, shayela udokotela wakho ngokushesha.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho anga-oda izivivinyo ezithile ngaphambi nangesikhathi sokwelashwa kwakho ukuze ahlole impendulo yomzimba wakho kumjovo we-pertuzumab.

Khuluma nodokotela wakho ngengozi yokwelashwa ngomjovo we-pertuzumab.

Umjovo wePertuzumab usetshenziswa kanye ne-trastuzumab (Herceptin) ne-docetaxel (Taxotere) ukwelapha uhlobo oluthile lomdlavuza webele oselusabalele nakwezinye izingxenye zomzimba. Ibuye isetshenziswe ngaphambi nangemva kokuhlinzwa kanye ne-trastuzumab (Herceptin) neminye imithi yokwelapha ngamakhemikhali ukwelapha izinhlobo ezithile zomdlavuza webele wesigaba sokuqala. Umjovo wePertuzumab usesigabeni semithi ebizwa ngama-antibody monoclonal. Isebenza ngokumisa ukukhula kwamangqamuzana omdlavuza.

Umjovo wePertuzumab uza njengesisombululo (uketshezi) ukujojelwa emthanjeni ngaphezu kwemizuzu engama-30 kuye kwangama-60 ngudokotela noma umhlengikazi esibhedlela noma esikhungweni sezokwelapha. Imvamisa inikezwa njalo emavikini amathathu. Ubude bokwelashwa kwakho buncike ekutheni umzimba wakho uphendula kahle kanjani emithini nasemiphumeleni oyitholayo.

Umjovo wePertuzumab ungadala ukusabela okungathi sína noma okungenzeka kusongele impilo okungenzeka ngenkathi kunikezwa umuthi nangesikhathi esithile ngemuva kwalokho. Udokotela wakho noma umhlengikazi uzokubuka ngokucophelela ngenkathi uthola umjovo ngamunye we-injection ye-pertuzumab, futhi okungenani ihora elilodwa ngemuva komthamo wakho wokuqala nemizuzu engamashumi amathathu ngemuva kokukhishwa kamuva. Tshela udokotela noma umhlengikazi wakho ngokushesha uma uhlangabezana nalezi zimpawu ezilandelayo ngesikhathi noma ngemuva nje kokumunyelwa kwakho: ukuphefumula, ukuphefumula noma ukuphefumula okunomsindo, ukudinwa, ubunzima bokugwinya, isifuba, ukuqubuka, ukulunywa, imfiva, ukubanda, ukukhathala, ikhanda, ubuthakathaka, ukuhlanza, ukunambitheka okungavamile emlonyeni, noma ubuhlungu bemisipha.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola umjovo we-pertuzumab,

• Tshela udokotela wakho kanye nosokhemisi uma une-aleji kumjovo we-pertuzumab, noma imiphi eminye imithi, noma iziphi izithako zomjovo we-pertuzumab. Buza udokotela wakho uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• utshele udokotela wakho uma uke welashwa ngamakhemikhali noma ngemisebe.
• tshela udokotela wakho uma uncelisa.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi uthola umjovo we-pertuzumab.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Shayela udokotela wakho khona manjalo uma ungakwazi ukugcina i-aphoyintimenti yokuthola isilinganiso somjovo we-pertuzumab.

Umjovo wePertuzumab ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isicanucanu
• isifo sohudo
• ukuncipha kokudla
• ubunzima bokulala noma ukulala
• ubuhlungu, ukuvutha, ukuba ndikindiki, noma ukuncinza ezandleni noma ezinyaweni
• amehlo anezinyembezi
• isikhumba esiphaphathekile noma esomile
• ukulahleka kwezinwele
• izilonda zomlomo

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu noma lezo ezisohlwini LWEZEXWAYISO EZIBALULEKILE nokuthi ZIYINI izingxenye, shayela udokotela wakho ngokushesha:

• umphimbo obuhlungu, umkhuhlane, amakhaza, ukukhwehlela, nezinye izimpawu zokutheleleka
• isicanucanu; ukuhlanza; ukulahlekelwa ukudla; ukukhathala; ukushaya kwenhliziyo okusheshayo; umchamo omnyama; ukuncipha kwenani lomchamo; ubuhlungu besisu; ukuquleka; ukusangana; noma amajaqamba kanye nama-spasms

Khuluma nodokotela wakho ngezingozi zokuthatha lo muthi.

Umjovo wePertuzumab ungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthola lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Umhlinzeki wakho wezokunakekelwa kwempilo uzogcina imithi yakho.

Udokotela wakho uzoku-oda ukuhlolwa kwelebhu ngaphambi kokuba uqale ukwelashwa kwakho ukuze ubone ukuthi umdlavuza wakho ungelashwa nge-pertuzumab.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Perjeta^®