I-Vortioxetine

-Delile

• Ngaphambi kokuthatha i-vortioxetine,
• IVortioxetine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu noma lezo ezibalwe ezigabeni EZIBALULEKILE ZESEXWAYISO noma ZOKUQapha, shayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

Inani elincane lezingane, intsha, nabantu abadala abancane (abangafika eminyakeni engama-24 ubudala) abathathe imishanguzo yokudambisa ingcindezi ('mood elevators') efana ne-vortioxetine phakathi nezifundo zomtholampilo baba ukuzibulala (becabanga ngokuzilimaza noma ukuzibulala noma ukuhlela noma ukuzama ukwenza kanjalo ). Izingane, intsha, kanye nabantu abadala abasebancane abathatha imishanguzo yokulwisana nokucindezelwa ukwelapha ukudangala noma ezinye izifo zengqondo bangase babe sethubeni lokuzibulala kunezingane, intsha kanye nabantu abadala abangawasebenzisi ama-anti-depressants ukwelapha lezi zimo. Kodwa-ke, kukhona nezingozi lapho ukucindezeleka kungelashwa ezinganeni nasebusheni. Khuluma nodokotela wengane yakho ngalezi zingozi nokuthi ingane yakho kufanele yini ithathe i-antidepressant. IVortioxetine ayikaze ifundwe ezinganeni ezineminyaka engaphansi kwengu-18 ubudala.

Kufanele wazi ukuthi impilo yakho yengqondo ingashintsha ngezindlela ezingalindelekile lapho uthatha i-vortioxetine noma amanye ama-anti-depressants noma ngabe umdala ngaphezu kweminyaka engama-24. Ungase uzibulale, ikakhulukazi ekuqaleni kokwelashwa kwakho futhi nganoma yisiphi isikhathi lapho umthamo wakho wanda noma wehla. Wena, umndeni wakho, noma umnakekeli wakho kufanele ushayele udokotela wakho ngokushesha uma uhlangabezana nalezi zimpawu ezilandelayo: ukucindezeleka okusha noma okuya kuba kubi; ukucabanga ngokuzilimaza noma ukuzibulala, noma ukuhlela noma ukuzama ukwenza kanjalo; ukukhathazeka ngokweqile; ukuyaluza; ukwethuka; ubunzima bokulala noma ukulala; isimilo esinolaka; ukucasuka; ukwenza ngaphandle kokucabanga; ukungahlaliseki okukhulu; nokuhlanya okungajwayelekile. Qiniseka ukuthi umndeni wakho noma umnakekeli wakho uyazi ukuthi yiziphi izimpawu ezingaba zimbi kakhulu ukuze bakwazi ukubiza udokotela uma ungakwazi ukuzifunela ukwelashwa wedwa.

Umhlinzeki wakho wezokunakekelwa kwempilo uzofuna ukukubona kaningi ngenkathi uthatha i-vortioxetine, ikakhulukazi ekuqaleni kokwelashwa kwakho. Qiniseka ukuthi ugcina wonke ama-aphoyintimenti wokuvakashelwa ehhovisi nodokotela wakho.

Udokotela noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa nge-vortioxetine. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungathola futhi iMihlahlandlela Yezokwelapha kwiwebhusayithi ye-FDA: http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm.

Kungakhathaliseki ukuthi uneminyaka emingaki, ngaphambi kokuba uthathe i-anti-depressant, wena, umzali wakho, noma umnakekeli wakho kufanele ukhulume nodokotela wakho ngezingozi nezinzuzo zokwelapha isimo sakho nge-anti-depressant noma ngezinye izindlela zokwelapha. Kufanele futhi ukhulume ngobungozi nezinzuzo zokungaselaphi isimo sakho. Kufanele wazi ukuthi ukuba nokudangala noma esinye isifo sengqondo kusandisa kakhulu ingozi yokuthi uzozibulala. Le ngozi ingaphezulu uma wena noma omunye emndenini wakho unenkinga yokuphazamiseka kwengqondo okuguquguqukayo (imizwa eguquka isuke ekucindezelekeni iye ekuthokozeni okungavamile) noma imania (edidekile, ejabule ngokweqile) noma uke wacabanga noma wazama ukuzibulala. Khuluma nodokotela wakho ngesimo sakho, izimpawu zakho, nomlando wakho wezempilo nowomndeni. Wena nodokotela wakho niyonquma ukuthi hlobo luni lwezokwelapha olulungele nina.

IVortioxetine isetshenziselwa ukwelapha ukudangala kubantu abadala. IVortioxetine isekilasini lemithi ebizwa nge-serotonin modulators. Isebenza ikakhulukazi ngokwandisa inani le-serotonin, into yemvelo ebuchosheni esiza ukugcina ukulinganisela kwengqondo.

IVortioxetine iza njengethebhulethi ezothathwa ngomlomo. Imvamisa kuthathwa nokudla noma ngaphandle kokudla kanye ngosuku. Thatha i-vortioxetine ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-vortioxetine njengoba nje iqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Udokotela wakho angalungisa umthamo wakho we-vortioxetine kuye ngokuthi uphendula kahle kangakanani ekwelashweni nokuthi ngabe unemiphumela emibi yini. Qiniseka ukuthi ukhuluma nodokotela wakho mayelana nokuthi uzizwa kanjani ngesikhathi sokwelashwa kwakho nge-vortioxetine.

Kungathatha amasonto ama-2 kuye kwayi-4 noma ngaphezulu ngaphambi kokuthi uzwe inzuzo ephelele ye-vortioxetine. Qhubeka uthathe i-vortioxetine noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-vortioxetine ngaphandle kokukhuluma nodokotela wakho. Uma ngokungazelelwe uyeka ukuthatha i-vortioxetine, ungahle ube nemiphumela emibi kubandakanya ikhanda, ukuqina kwemisipha, ukushintsha kwemizwelo, ukuqhuma kwentukuthelo, isiyezi, noma ikhala eligijimayo. Udokotela wakho anganciphisa umthamo wakho kancane kancane.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-vortioxetine,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-vortioxetine, noma imiphi eminye imithi, noma iziphi izithako ezikumaphilisi e-vortioxetine. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
• Tshela udokotela wakho uma uthatha i-monoamine oxidase (MAO) inhibitors, kufaka phakathi i-isocarboxazid (Marplan), linezolid (Zyvox), methylene blue, phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), ne-tranylcypromine (i-Parnate) noma uma ngiyekile ukuwaphuza emasontweni amabili edlule. Udokotela wakho angakutshela ukuthi ungathathi i-vortioxetine. Uma uyeka ukuthatha i-vortioxetine, kufanele ulinde okungenani izinsuku ezingama-21 ngaphambi kokuqala ukuthatha i-MAO inhibitor.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, namavithamini, izithako zokudla okunomsoco ozithathayo noma ohlela ukuzithatha. Qiniseka ukuthi usho noma ikuphi kokulandelayo: ama-anticoagulants (’ama-thinner egazi’) njenge-warfarin (i-Coumadin, i-Jantoven); imishanguzo elwa nezidakamizwa ('mood elevators') efana ne-amitriptyline, amoxapine, clomipramine (Anafranil), desipramine (Norpramin), doxepin (Silenor), imipramine (Tofranil), nortriptyline (Aventyl, Pamelor), protriptyline (Vivactiline), ; i-bupropion (i-Aplenzin, i-Forfivo, i-Wellbutrin, i-Zyban); i-aspirin nezinye izidakamizwa ezingezona ukuvuvukala (ama-NSAID) njenge-ibuprofen (Advil, Motrin) ne-naproxen (Aleve, Naprosyn); buspirone; carbamazepine (Carbatrol, Equetro, Tegretol); isisu (‘amaphilisi amanzi’); i-fentanyl (Actiq, iDuragesic, iFentora, iLazanda, nabanye); i-lithium (i-Lithobid); imithi yokugula kwengqondo; imithi yezinhlungu ze-migraine ezifana ne-almotriptan (Axert), i-eletriptan (i-Relpax), i-frovatriptan (i-Frova), i-naratriptan (i-Amerge), i-rizatriptan (i-Maxalt), i-sumatriptan (i-Imitrex), ne-zolmitriptan (iZomig); i-phenytoin (iDilantin, Phenytek); i-quinidine (ku-Nuedexta); i-rifampin (i-Rifadin, i-Rimactane); amanye ama-serotonin-reuptake inhibitors akhethiwe njenge-citalopram (Celexa), i-escitalopram (Lexapro), i-fluoxetine (i-Prozac, i-Sarafem, e-Symbyax), i-fluvoxamine (i-Luvox), i-paroxetine (i-Brisdelle, i-Prozac, i-Pexeva), ne-sertraline (i-Zoloft); i-serotonin ne-norepinephrine reuptake inhibitors efana ne-duloxetine (Cymbalta), desvenlafaxine (Khedezla, Pristiq), ne-venlafaxine (Effexor); kanye ne-tramadol (Conzip, Ulltram). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• utshele udokotela wakho ukuthi yimiphi imikhiqizo yamakhambi kanye nezithako zokudla okunomsoco ozithathayo, ikakhulukazi iSt John's wort ne-tryptophan.
• Tshela udokotela wakho ukuthi unezinga eliphansi le-sodium egazini lakho, uma uphuza noma wake waphuza utshwala obuningi, futhi uma uke waquleka noma waba nezinkinga zokugula, noma ukopha noma isifo sesibindi.
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha i-vortioxetine, shayela udokotela wakho. IVortioxetine ingadala izinkinga ezinganeni ezisanda kuzalwa ngemuva kokubeletha uma zithathwa ezinyangeni ezimbalwa ezedlule zokukhulelwa.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, noma ukuhlolwa kwezokwelapha okubandakanya odayi, tshela udokotela noma udokotela wamazinyo ukuthi uthatha i-vortioxetine.
• kufanele wazi ukuthi i-vortioxetine ingathinta ukwahlulela, ukucabanga nokunyakaza kwakho. Ungashayeli imoto noma usebenzise imishini uze wazi ukuthi lo muthi ukuthinta kanjani.
• buza udokotela wakho mayelana nokusetshenziswa okuphephile kweziphuzo ezidakayo ngenkathi uthatha i-vortioxetine.
• kufanele wazi ukuthi i-vortioxetine ingadala i-angle-closure glaucoma (isimo lapho uketshezi luvinjwe ngokuzumayo futhi lungakwazi ukuphuma esweni kubangele ukwanda okusheshayo, okunzima kwengcindezi yamehlo okungaholela ekulahlekelweni kombono). Khuluma nodokotela wakho ngokuhlolwa iso ngaphambi kokuba uqale ukusebenzisa le mithi. Uma unesicanucanu, ubuhlungu beso, izinguquko embonweni, njengokubona izindandatho ezinemibala ezungeze izibani, nokuvuvukala noma ukubomvu ngaphakathi noma ezungeze iso, shayela udokotela wakho noma uthole ukwelashwa okuphuthumayo ngokushesha.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

IVortioxetine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isicanucanu
• ukuhlanza
• isifo sohudo
• ukuqunjelwa
• igesi
• umlomo owomile
• isiyezi
• amaphupho angajwayelekile
• izinguquko kwisifiso sobulili noma ikhono

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu noma lezo ezibalwe ezigabeni EZIBALULEKILE ZESEXWAYISO noma ZOKUQapha, shayela udokotela wakho ngokushesha:

• ukuqubuka
• isifuba
• ukulunywa
• ukuvuvukala kwamehlo, ubuso, izindebe, ulimi, noma umphimbo
• ukushaqeka
• ukuphefumula kanzima noma ukugwinya
• ukulimaza noma ukopha okungavamile
• umkhuhlane, ukujuluka, ukudideka, ukushaya kwenhliziyo okusheshayo noma okungajwayelekile, nokuqina kwemisipha okunzima
• ekhaleni
• ikhanda
• ubunzima bokugxila
• izinkinga zememori
• ukudideka
• ubuthakathaka
• ukungazinzi
• ukusangana
• ukuquleka
• isithuthwane
• ikhoma (ukulahlekelwa ukwazi isikhathi esithile)

IVortioxetine ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• isicanucanu
• ukuhlanza
• isiyezi
• isifo sohudo
• ubuhlungu besisu
• ukulunywa
• ubuthongo
• ukuqhuma

Gcina wonke ama-aphoyintimenti nodokotela wakho.

Ngaphambi kokwenza noma yiluphi uvivinyo lwe-laboratory (ikakhulukazi lezo ezibandakanya i-methylene blue), tshela udokotela wakho nabasebenzi be-laboratory ukuthi uthatha i-vortioxetine.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Trintellix^®
• I-Brintellix^®¶

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