Inaliti ye-Albiglutide

-Delile

• Ngaphambi kokusebenzisa umjovo we-albiglutide,
• Lo muthi ungadala ushintsho kushukela wakho wegazi. Kufanele wazi izimpawu zikashukela wegazi ophansi futhi ophakeme nokuthi yini okufanele uyenze uma unalezi zimpawu.
• Umjovo we-Albiglutide ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SEXWAYISO, yeka ukusebenzisa umjovo we-albiglutide bese ushayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
• Izimpawu zokudlula ngokweqile zingafaka:

Umjovo we-Albiglutide ngeke usatholakala e-United States ngemuva kukaJulayi 2018. Uma njengamanje usebenzisa umjovo we-albiglutide, kufanele ushayele udokotela wakho ukuze axoxe ngokushintshela kolunye ukwelashwa.

Umjovo we-Albiglutide ungakhuphula ubungozi bokuthi uzoba nezicubu zomgudu wegilo, kufaka phakathi i-medullary thyroid carcinoma (MTC; uhlobo lomdlavuza wegilo). Izilwane zaselabhorethri ezinikezwe imishanguzo efana ne-albiglutide yathuthuka izicubu, kepha akwaziwa ukuthi le mithi iyayandisa ingozi yezimila kubantu. Tshela udokotela wakho ukuthi ngabe wena noma omunye emndenini wakho une-MTC noma i-Multiple Endocrine Neoplasia syndrome type 2 (MEN 2; isimo esidala izicubu ezingxenyeni ezingaphezu kweyodwa emzimbeni). Uma kunjalo, udokotela wakho uzokutshela ukuthi ungasebenzisi umjovo we-albiglutide. Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: isigaxa noma ukuvuvukala entanyeni; ukushaqeka; ubunzima bokugwinya; noma ukuphefumula okuncane.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho anga-oda izivivinyo ezithile ukuze ahlole impendulo yomzimba wakho kumjovo we-albiglutide.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa ngomjovo we-albiglutide futhi isikhathi ngasinye lapho ugcwalisa khona incwadi kadokotela. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) noma iwebhusayithi yomkhiqizi ukuthola i-Medication Guide.

Khuluma nodokotela wakho ngezingozi zokusebenzisa umjovo we-albiglutide.

Umjovo we-Albiglutide usetshenziswa nohlelo lokudla nokuzivocavoca ukulawula amazinga kashukela kubantu abadala abanesifo sikashukela sohlobo lwesibili (isimo lapho umzimba ungasebenzisi khona i-insulin ngokwejwayelekile ngakho-ke awukwazi ukulawula inani likashukela egazini) lapho eminye imithi ingalawuleki amazinga ngokwanele. Umjovo we-Albiglutide awusetshenziswanga ukwelapha uhlobo lwesifo sikashukela sohlobo 1 (isimo lapho umzimba ungakhiqizi khona i-insulin ngakho-ke awukwazi ukulawula inani likashukela egazini) noma isifo sikashukela ketoacidosis (isimo esibi esingavela uma ushukela wegazi ongelashwa) . Umjovo we-Albiglutide usesigabeni semithi ebizwa nge-incretin mimetics. Isebenza ngokusiza ama-pancreas ukukhipha inani elifanele le-insulin lapho amazinga kashukela egazi ephezulu. I-insulin isiza ukuhambisa ushukela egazini uye kwezinye izicubu zomzimba lapho usetshenziselwa khona amandla. Umjovo we-Albiglutide nawo usebenza ngokunciphisa ukuhamba kokudla esiswini.

Ngokuhamba kwesikhathi, abantu abanesifo sikashukela kanye noshukela ophakeme wegazi bangakhula babe nezinkinga ezinkulu noma ezisongela impilo, kufaka phakathi isifo senhliziyo, isifo sohlangothi, izinkinga zezinso, ukulimala kwemizwa nezinkinga zamehlo. Ukusebenzisa imithi, ukwenza izinguquko endleleni ophila ngayo (isb., Ukudla, ukuzivocavoca, ukuyeka ukubhema), nokuhlola njalo ushukela wegazi lakho kungasiza ukuphatha isifo sikashukela futhi kuthuthukise impilo yakho. Lokhu kwelashwa kunganciphisa namathuba akho okuhlaselwa yisifo senhliziyo, isifo sohlangothi, noma ezinye izinkinga ezihlobene nesifo sikashukela njengokuhluleka kwezinso, ukulimala kwemizwa (okundikindiki, imilenze ebandayo noma izinyawo; ukwehla kwekhono lezocansi kwabesilisa nabesifazane), izinkinga zamehlo, kufaka phakathi izinguquko noma ukulahleka kombono, noma isifo sezinsini. Udokotela wakho nabanye abahlinzeki bezokunakekelwa kwezempilo bazokhuluma nawe ngendlela engcono yokuphatha isifo sikashukela.

Umjovo we-Albiglutide uza njengempuphu ezoxutshwa namanzi ngepeni lokufaka elifakiwe ukuze ujove ngaphansi (kwesikhumba). Imvamisa ijovwa kanye ngesonto ngaphandle kokubheka ukudla. Sebenzisa umjovo we-albiglutide ngosuku olufanayo ngesonto ngalinye nganoma yisiphi isikhathi sosuku. Ungalushintsha usuku lwesonto olusebenzisa i-albiglutide inqobo nje uma sekunezinsuku ezi-4 noma ngaphezulu selokhu wasebenzisa umthamo wakho wokugcina. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Sebenzisa umjovo we-albiglutide njengoba uqondisiwe.Ungayisebenzisi ngaphezulu noma ngaphansi kwayo noma uyisebenzise kaningi kunokuyalelwa ngudokotela wakho.

Umjovo we-Albiglutide ulawula isifo sikashukela kepha awuselaphi. Qhubeka nokusebenzisa umjovo we-albiglutide noma ngabe uzizwa uphilile. Ungayeki ukusebenzisa umjovo we-albiglutide ngaphandle kokukhuluma nodokotela wakho.

I-Albiglutide iza ezibayeni zokufaka ezifakwe kuqala eziqukethe imishanguzo eyanele yedosi eyodwa. Faka njalo i-albiglutide epeni layo lokufaka elithandayo; ungalinge uyixube nomunye umuthi.

Funda ngokucophelela imiyalelo yomkhiqizi yokusetshenziswa eza nomuthi. Le miyalo ichaza ukuthi ungalungiswa futhi ujovwe kanjani umjovo we-albiglutide. Qiniseka ukuthi ubuza usokhemisi noma udokotela wakho uma unanoma yimiphi imibuzo mayelana nokuthi ungayilungisa kanjani noma uyijove kanjani le mithi.

Njalo bheka i-albiglutide yakho ngaphambi kokuyijova. Kufanele icace, iphuzi, futhi ingabi nezinhlayiya eziqinile.

Ungafaka i-albiglutide yakho engalweni yakho ephezulu, ethangeni, noma esiswini. Ungalokothi ujove i-albiglutide emthanjeni noma emisipheni. Shintsha (jikelezisa) indawo yokujova ngaphakathi kwendawo ekhethiwe ngomthamo ngamunye. Ungafaka i-albiglutide ne-insulini endaweni efanayo yomzimba, kepha akufanele unikeze imijovo eceleni komunye nomunye.

Ungalokothi uphinde usebenzise noma wabelane ngezinaliti noma amapeni. Njalo sebenzisa inaliti entsha ngomjovo ngamunye. Lahla izinaliti esitsheni esingamelana nokubhoboza. Buza udokotela wakho noma usokhemisi ukuthi ungasilahla kanjani isitsha esimelana nokubhoboza.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokusebenzisa umjovo we-albiglutide,

• Tshela udokotela kanye nosokhemisi wakho uma ungenwe i-albiglutide, noma imiphi eminye imithi, noma iziphi izithako zomjovo we-albiglutide. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Kubaluleke kakhulu ukutshela udokotela wakho ngayo yonke imithi oyiphuzayo ngomlomo ngoba i-albiglutide ingashintsha indlela umzimba wakho oyithatha ngayo le mithi. Futhi qiniseka ukuthi ukhuluma ngemithi ye-insulin noma yomlomo yesifo sikashukela ikakhulukazi i-sulfonylureas, kufaka phakathi i-chlorpropamide (i-Diabinese), i-glimepiride (i-Amaryl, e-Avandaryl, e-Duetact), i-glipizide (i-Glucotrol), i-glyburide (i-DiaBeta, i-Glynase, e-Glucovance), i-tolazamide, ne-tolbutamide . Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• tshela udokotela wakho uma uke waba ne-pancreatitis noma (wake wavuvukala amanyikwe); izinkinga ezinzima zesisu, kufaka phakathi i-gastroparesis (ukuhamba kancane kokudla kusuka esiswini kuya emathunjini amancane) noma izinkinga zokugaya ukudla; noma isifo sezinso noma sesibindi.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi usebenzisa umjovo we-albiglutide, shayela udokotela wakho.
• buza udokotela wakho ukuthi wenzeni uma ugula, uba nesifo noma umkhuhlane, noma uhlangabezana nokucindezeleka okungavamile. Lezi zimo zingathinta ushukela wegazi lakho kanye nenani le-albiglutide ongayidinga.

Qiniseka ukuthi ulandela zonke izincomo zokuzivocavoca nezokudla ezenziwa ngudokotela wakho noma udokotela odlayo.

Sebenzisa umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma kungaphezu kwezinsuku ezi-3 ngemuva komthamo ongabanjwanga, yeqa umthamo ophuthelwe bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungasebenzisi umthamo ophindwe kabili ukwenza okulahlekile.

Lo muthi ungadala ushintsho kushukela wakho wegazi. Kufanele wazi izimpawu zikashukela wegazi ophansi futhi ophakeme nokuthi yini okufanele uyenze uma unalezi zimpawu.

Umjovo we-Albiglutide ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isifo sohudo
• isicanucanu
• isilungulela
• ububomvu, ukuvuvukala, noma ukulunywa esizeni somjovo
• ukukhwehlela noma izimpawu ezifana nomkhuhlane

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SEXWAYISO, yeka ukusebenzisa umjovo we-albiglutide bese ushayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ubuhlungu obuqhubekayo obuqala ngaphezulu kwesobunxele noma maphakathi nesisu kepha bungadlulela emuva
• ukuhlanza
• isifuba
• ukuqubuka
• ukulunywa
• ukuphefumula kanzima

Umjovo we-Albiglutide ungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi usebenzisa lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Yigcine ekamelweni lokushisa kuze kube amasonto ama-4 ngaphambi kokuyisebenzisa noma esiqandisini, futhi kude nokushisa nomswakama okweqile (hhayi endlini yangasese). Ungafrizi.

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka:

• isicanucanu esinzima nokuhlanza

Ungavumeli omunye umuntu asebenzise imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Tanzeum^®