Inaliti ye-Belinostat

-Delile

• Ngaphambi kokuthola umjovo we-belinostat,
• Umjovo we-Belinostat ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

I-Belinostat isetshenziselwa ukwelapha i-peripheral T-cell lymphoma (PTCL; uhlobo lomdlavuza oluqala ngohlobo oluthile lwamaseli kumasosha omzimba) olungazange luthuthuke noma olubuyile ngemuva kokwelashwa ngeminye imithi. I-Belinostat isekilasini lemithi ebizwa nge-histone deacetylase inhibitors. Isebenza ngokubulala amangqamuzana omdlavuza.

I-Belinostat iza njengesisombululo (uketshezi) sokujova ngomjovo (emthanjeni) ngudokotela noma umhlengikazi esibhedlela noma emtholampilo. Imvamisa inikezwa isikhathi esiyimizuzu engama-30 kanye ngosuku ngezinsuku 1 kuye ku-5 zomjikelezo wezinsuku ezingama-21. Ukwelashwa kwakho kuzoqhubeka kuze kube yilapho isimo sakho siba sibi noma uba nemiphumela emibi kakhulu.

Udokotela wakho angadinga ukulungisa umthamo wakho noma ayeke ukwelashwa kwakho uma uhlangabezana nemiphumela ethile emibi. Qiniseka ukuthi utshela udokotela wakho ukuthi uzizwa kanjani ngenkathi welashwa ngomjovo we-belinostat.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola umjovo we-belinostat,

• Tshela udokotela wakho kanye nosokhemisi uma une-allergen kumjovo we-belinostat, noma imiphi eminye imithi, noma yiziphi izithako zomjovo we-belinostat. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyisebenzisa noma oyisebenzisayo. Qiniseka ukuthi usho noma yikuphi okulandelayo: indinavir (Crixivan), ketoconazole (Nizoral), noma i-ritonavir (iNorvir, eKaletra). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• Tshela udokotela wakho ukuthi wake wakuthola ukwelashwa ngeminye imithi yokwelapha ngamakhemikhali noma uma unayo noma ucabanga ukuthi ungahle ube nohlobo oluthile lokutheleleka manje. Phinda utshele udokotela wakho uma uke waba nesifo sezinso noma sesibindi.
• utshele udokotela wakho uma ukhulelwe, ungakhulelwa, noma uhlele ukukhulelwa. Akufanele ukhulelwe ngenkathi uthola umjovo we-belinostat. Khuluma nodokotela wakho ngezindlela zokulawula ukubeletha ongazisebenzisa ngesikhathi sokwelashwa kwakho. Uma ukhulelwa ngenkathi uthola umjovo we-belinostat, shayela udokotela wakho ngokushesha. Umjovo we-Belinostat ungalimaza umbungu.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi uthola umjovo we-belinostat.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Umjovo we-Belinostat ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isicanucanu
• isifo sohudo
• ukuhlanza
• ukuqunjelwa
• ikhanda
• ukukhathala
• ukuncipha kokudla
• ubuhlungu endaweni yomjovo
• ukuvuvukala kwezandla, izinyawo, noma amaqakala

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

• umkhuhlane, ukukhwehlela, ukugodola, ubuhlungu bemisipha, izimpawu ezifana nomkhuhlane, noma ezinye izimpawu zokutheleleka
• ukuchama okubuhlungu, okuvamile, okushisayo noma okunzima
• ukopha okungajwayelekile noma ukulinyazwa
• isiyezi
• ukuphelelwa umoya
• ukuqubuka
• ukulunywa
• ubuhlungu endaweni engakwesokudla esiswini
• ukuphuzi kwesikhumba noma kwamehlo
• umchamo omnyama

Umjovo we-Belinostat ungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthola lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho kumjovo we-belinostat.

Buza udokotela wakho noma usokhemisi noma imiphi imibuzo onayo ngemithi yakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Beleodaq^®