Suvorexant

-Delile

• Ngaphambi kokuthatha i-suvorexant,
• ISuvorexant ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu noma lezo ezisohlwini lwe-SPECIAL PRECAUTIONS section, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
• Izimpawu zokudlula ngokweqile zingafaka:

ISuvorexant isetshenziselwa ukwelapha ukuqwasha (ubunzima bokulala noma ukulala).ISuvorexant isekilasini lemithi ebizwa ngama-orexin receptor antagonists. Isebenza ngokuvimba ukusebenza kwento ethile yemvelo ebuchosheni ebangela ukuphaphama.

ISuvorexant iza njengethebhulethi ezothathwa ngomlomo. Imvamisa kuthathwa kanye ngosuku, uma kudingeka, kungakapheli imizuzu engama-30 ngaphambi kokulala. ISuvorexant ingathathwa nokudla noma ngaphandle kokudla kepha izoqala ukusebenza ngokushesha uma ithathwa isisu esingenalutho. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-suvorexant njengoba nje kuqondisiwe. Ungalokothi uthathe umthamo ongaphezu koyedwa we-suvorexant ngosuku noma ngabe usenenkinga yokulala noma ukulala.

Mhlawumbe uzolala ngokushesha ngemuva kokuthatha i-suvorexant futhi uzohlala ulele isikhashana ngemuva kokuphuza umuthi. Hlela ukulala ngemuva nje kokuphuza umuthi nokuhlala embhedeni okungenani amahora ayi-7. Ungathathi i-suvorexant uma ungeke ukwazi ukuhlala ulele ngenombolo edingekayo yamahora ngemuva kokuthatha umuthi. Uma uvuka ngokushesha kakhulu ngemuva kokuthatha i-suvorexant, ungahle wehlelwe ukozela nobunzima bokushayela noma ukwenza imisebenzi edinga ukuqapha.

Izinkinga zakho zokulala kufanele zithuthuke kungakapheli izinsuku eziyi-7 kuya kwezingu-10 ngemuva kokuqala ukuthatha i-suvorexant. Shayela udokotela wakho uma izinkinga zakho zokulala zingathuthuki ngalesi sikhathi noma uma ziba zimbi kakhulu nganoma yisiphi isikhathi lapho welashwa.

Udokotela wakho mhlawumbe uzokuqala ngomthamo ophansi we-suvorexant futhi angakhuphula kancane umthamo wakho uma ukulala kwakho kungathuthuki. Udokotela wakho futhi anganciphisa umthamo wakho we-suvorexant noma akutshele ukuthi uyeke ukuthatha umuthi uma kukwenza uzizwe ukozela kakhulu emini.

Gwinya wonke amaphilisi; ungawahlukanisi, ungawahlafune noma uwagxoze.

ISuvorexant ingaba umkhuba wokwakha. Ungathathi umthamo omkhulu, uthathe kaningi, noma uthathe isikhathi eside kunokuyalelwa ngudokotela wakho.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa nge-suvorexant futhi isikhathi ngasinye lapho ugcwalisa umuthi wakho. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) noma iwebhusayithi yomkhiqizi ukuthola i-Medication Guide.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-suvorexant,

• Tshela udokotela kanye nosokhemisi wakho uma une-aleji ku-suvorexant, noma imiphi eminye imithi, noma iziphi izithako ezikumaphilisi e-suvorexant. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma ikuphi kokulandelayo: imishanguzo yokubulala amagciwane efana ne-fluconazole (Diflucan), itraconazole (Onmel, Sporanox), ketoconazole, ne-posaconazole (Noxafil); i-aprepitant (Hlela); i-boceprevir (i-Victrelis); carbamazepine (Carbatrol, Equetro); i-ciprofloxacin (Cipro); i-clarithromycin (i-Biaxin, ku-Prevpac); i-conivaptan (iVaprisol); i-digoxin (i-Lanoxin); i-diltiazem (iCardizem, iTiazac); i-erythromycin (EES.S., i-Ery-tab); imatinib (Gleevec); imishanguzo ethile yegciwane lengculazi (i-HIV) efana ne-atazanavir (Reyataz), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, e Kaletra), ne-saquinavir (Invirase); imishanguzo yokukhathazeka, ukugula kwengqondo, ubuhlungu nokuquleka; nefazodone; i-phenytoin (iDilantin, Phenytek); i-rifampin (i-Rifadin, i-Rimactane); iTelaprevir (Incivek); i-telithromycin (Ketek); i-tricyclic antidepressants efana ne-amitriptyline, amoxapine, clomipramine (Anafranil), desipramine (Norpramin), doxepin (Silenor), imipramine (Tofranil), nortriptyline (Pamelor), protriptyline (Vivactil), ne-trimontramine (Surimipramine) i-verapamil (Verelan, Covera); isidambisi; amaphilisi okulala; kanye nezithambisi. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• Tshela udokotela wakho uma une-narcolepsy (isimo esibangela ukulala ngokweqile emini). Udokotela wakho mhlawumbe uzokutshela ukuthi ungathathi i-suvorexant.
• tshela udokotela wakho uma uphuza noma wake waphuza utshwala obuningi, wasebenzisa noma wake wasebenzisa izidakamizwa zasemgwaqweni, noma usebenzise ngokweqile imithi kadokotela. Phinda utshele udokotela wakho ukuthi ukhuluphele ngokweqile, nokuthi ngabe uke waba nokudangala noma wake waba nakho yini; ukugula ngengqondo; imicabango yokuzilimaza noma ukuzibulala noma ukuzama ukwenza kanjalo; isifo esingelapheki samaphaphu (COPD; iqembu lezifo ezithinta amaphaphu nemigwaqo yomoya); i-apnea yokulala (isimo lapho ukuphefumula kuyeka khona izikhathi eziningi ebusuku); noma yiziphi ezinye izinkinga zamaphaphu noma zokuphefumula; ubuthakathaka bemisipha obenzeka ngokuzumayo; noma isifo sesibindi.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha i-suvorexant, shayela udokotela wakho.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi uthatha i-suvorexant.
• kufanele wazi ukuthi i-suvorexant ingadala ukozela, yehlise ukuqapha kwengqondo, nezinkinga ngokuxhumeka ngemuva kosuku uyithathile, futhi le miphumela ingahlala ezinsukwini ezimbalwa ngemuva kokuyeka umuthi. Lokhu kungakhuphula ubungozi bokuwa okungadala ukulimala kanzima, ikakhulukazi uma usukhulile. ISuvorexant nayo ingaphazamisa ikhono lakho lokushayela futhi inyuse nengozi yokulala ngenkathi ushayela. Ikhono lakho lokushayela noma ukusebenzisa imishini ngosuku olulandelayo ngemuva kokuthatha i-suvorexant lingakhubazeka noma ngabe uzizwa uphapheme ngokuphelele. Ungashayeli imoto, sebenzisa imishini, noma wenze noma yimuphi umsebenzi oyingozi kungakapheli amahora ayisishiyagalombili uthathe i-suvorexant futhi uze uzizwe uphapheme ngokuphelele. Khuluma nodokotela wakho ngezingozi zokushayela noma ukusebenzisa imishini ngemuva kokuthatha i-suvorexant.
• ungaphuzi utshwala ngenkathi uthatha i-suvorexant. Utshwala bungenza imiphumela emibi evela ku-suvorexant ibe yimbi kakhulu.
• kufanele wazi ukuthi abanye abantu abathathe i-suvorexant bavuka embhedeni bashayela izimoto zabo, balungisa futhi badla ukudla, baya ocansini, bashaya izingcingo, noma benza ezinye izinto ngenkathi belele kancane. Ngemuva kokuvuka kwabo, laba bantu bebevame ukungakhumbuli abakwenzile. Shayela udokotela wakho ngokushesha uma uthola ukuthi ubeshayela noma wenza noma yini enye engajwayelekile ngenkathi ulele.
• kufanele wazi ukuthi isimilo sakho nempilo yakho yengqondo kungashintsha ngezindlela ezingalindelekile ngenkathi uthatha lo muthi. Lezi zinguquko zingabangelwa yi-suvorexant noma zingabangelwa ukugula ngokomzimba noma kwengqondo osuvele unakho noma okudala ngesikhathi sokwelashwa kwakho. Tshela udokotela wakho khona manjalo uma uhlangabezana nalezi zimpawu ezilandelayo: ulaka, isimilo noma isimilo esiphuma ngokungajwayelekile, ukubona izinto ezingekho (ukubona izinto noma ukuzwa amazwi angekho), uzizwe ungaphandle komzimba wakho, izinkinga zememori, ukukhathazeka ukudangala okusha noma okuya ngokuya kuba kubi, ucabanga ukuzibulala noma ukuzama ukwenza kanjalo, ukudideka, kanye nolunye uguquko emicabangweni yakho ejwayelekile, imizwa, noma indlela oziphatha ngayo. Qiniseka ukuthi umndeni wakho uyazi ukuthi yiziphi izimpawu ezingaba zimbi kakhulu ukuze bakwazi ukushayela udokotela uma ungakwazi ukufuna ukwelashwa uwedwa.

Khuluma nodokotela wakho ngokudla isithelo samagilebhisi nokuphuza ijusi lamagilebhisi ngenkathi uthatha lo muthi.

Lo muthi uvame ukuphathwa lapho kudingeka. Ungathatha i-suvorexant noma ngabe ingemuva kwesikhathi esivamile, inqobo nje uma uzokwazi ukuhlala embhedeni ngenombolo edingekayo yamahora ngemuva kokuyithatha.

ISuvorexant ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ukozela
• isiyezi
• ikhanda
• amaphupho angajwayelekile
• umlomo owomile
• ukukhwehlela
• isifo sohudo

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu noma lezo ezisohlwini lwe-SPECIAL PRECAUTIONS section, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukwehluleka okwesikhashana ukunyakaza noma ukukhuluma kuze kube yimizuzu eminingana ngenkathi uyolala noma uvuka
• ubuthakathaka bomlenze besikhashana emini noma ebusuku

ISuvorexant ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Ukugcine ekamelweni lokushisa kude nokukhanya, ukushisa okweqile nomswakama (hhayi endlini yangasese).

Gcina i-suvorexant endaweni ephephile ukuze kungabikho omunye umuntu ongayithatha ngephutha noma ngenhloso. Gcina umbhalo walokho ukuthi kushiywe amaphilisi amangaki ukuze wazi ukuthi kukhona yini okungekho.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka:

• ukozela ngokweqile

Gcina wonke ama-aphoyintimenti nodokotela wakho.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. ISuvorexant yinto elawulwayo. Okubhalwe phansi kungagcwaliswa izikhathi ezimbalwa kuphela; buza usokhemisi wakho uma unemibuzo.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Belsomra^®