Isavuconazonium

-Delile

• Ngaphambi kokuthatha i-isavuconazonium,
• I-Isavuconazonium ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

I-Isavuconazonium isetshenziselwa ukwelapha ukutheleleka okunzima okufana ne-aspergillosis (isifo esikhunta esiqala emaphashini bese sisakazeka egazini liye kwezinye izitho) kanye ne-mucormycosis (isifo sokukhunta esivame ukuqala ezonweni, ebuchosheni noma emaphashini). I-Isavuconazonium isekilasini lemithi ebizwa ngama-azole antifungals. Isebenza ngokunciphisa ukukhula kwesikhunta okubangela ukutheleleka.

I-Isavuconazonium iza njengephilisi elizothathwa ngomlomo. Imvamisa kuthathwa ngokudla noma ngaphandle kokudla njalo emahoreni ayisishiyagalombili kumithamo yokuqala eyisithupha bese kuthi kanye ngosuku. Thatha i-isavuconazonium ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-isavuconazonium njengoba iqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Gwinya wonke amaphilisi; ungawavuli, ungawahlafune, ungawaqedi noma uwagxoze.

Ubude bokwelashwa kwakho buxhomeke empilweni yakho ejwayelekile, uhlobo lokutheleleka onalo, nokuthi uphendula kahle kanjani emithini. Qhubeka uthathe i-isavuconazonium noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-isavuconazonium ngaphandle kokukhuluma nodokotela wakho.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-isavuconazonium,

• Tshela udokotela kanye nosokhemisi wakho uma uxabana ne-isavuconazonium, i-fluconazole, i-itraconazole, i-ketoconazole, i-posaconazole, i-voriconazole, noma imiphi eminye imithi, noma iziphi izithako ezikuma-capsule e-isavuconazonium. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho uma uthatha i-carbamazepine (Carbatrol, Tegretol), ketoconazole (Nizoral), phenobarbital, rifampin (Rifadin, Rifamate), ritonavir (Norvir, in Kaletra), noma iSt John's wort. Udokotela wakho uzokutshela ukuthi ungathathi i-isavuconazonium uma uthatha eyodwa noma ngaphezulu yale mithi.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma ikuphi kokulandelayo: ), i-sirolimus (i-Rapamune), noma i-tacrolimus (i-Prograf). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo eminingi ingaxhumana ne-isavuconazonium, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho nalawo angaveli kulolu hlu.
• Tshela udokotela wakho uma wena noma omunye emndenini wakho enesifo esifushane se-QT (isimo esandisa ubungozi bokushaya kwenhliziyo okungajwayelekile, isiyezi, ukuquleka noma ukufa ngokuzuma). Udokotela wakho mhlawumbe uzokutshela ukuthi ungathathi i-isavuconazonium.
• utshele udokotela wakho uma uke waba nezinkinga zenhliziyo noma zesibindi noma wake waba nazo.
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha i-isavuconazonium, shayela udokotela wakho.

Khuluma nodokotela wakho ngokudla isithelo samagilebhisi nokuphuza ijusi lamagilebhisi ngenkathi uthatha lo muthi.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Isavuconazonium ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isifo sohudo
• ukuqunjelwa
• ikhanda
• ukuhlungu obusemhlane
• ukukhwehlela
• ubunzima bokulala noma ukulala
• ukukhathazeka
• ukuyaluza
• ukudideka
• ukuncipha kokudla

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• isifuba
• ukuqubuka
• ukulunywa
• isikhumba esihlabayo noma esishayayo
• isicanucanu
• ukuhlanza
• ukuphuzi kwesikhumba noma kwamehlo
• ukukhathala ngokweqile
• izimpawu ezinjengomkhuhlane
• ubuhlungu bemisipha, amajaqamba, noma ubuthakathaka
• ukushaya kwenhliziyo okungajwayelekile
• ukuvuvukala kwezandla, izinyawo, izingalo noma imilenze
• ukuphefumula kanzima noma ukugwinya

I-Isavuconazonium ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. I-Isavuconazonium iza ngokufakwa kwamablister kanti isigaba ngasinye se-blister sinamaphakethe amabili. Iphakethe langakwesobunxele line-desiccant (iphakethe elincane eliqukethe into edonsa umswakama ukugcina umuthi womile) kanti nephakethe elifanele linomuthi. Vula kuphela iphakethe le-isavuconazonium bese ushiya i-desiccant emaphaketheni. Ungasusi i-isavuconazonium emaphaketheni asekuqaleni uze ulungele ukuthatha umthamo wakho. Ungafaki i-isavuconazonium emabhokisini amaphilisi noma abahleli bamaphilisi. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• ikhanda
• isiyezi
• ubuhlungu, ukushisa, noma ukuncinza ezandleni noma ezinyaweni
• ukozela
• ubunzima bokugxila
• shintsha ngomqondo wokunambitha
• umlomo owomile
• ukuba ndikindiki emlonyeni
• isifo sohudo
• ukuhlanza
• ukubomvu ngokungazelelwe kobuso, intamo, noma isifuba esingenhla
• ukukhathazeka
• ukungahlaliseki
• ukushaya ngamandla noma ukushaya kwenhliziyo okusheshayo
• ukuzwela kwamehlo ekukhanyeni
• ubuhlungu obuhlangene

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho angalawula izivivinyo ezithile zebhu ukuze ahlole impendulo yomzimba wakho ku-isavuconazonium.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• UCremba^®