Ixazomib

-Delile

• Ngaphambi kokuthatha ixazomib,
• Ixazomib ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu shayela udokotela wakho ngokushesha:

Ixazomib isetshenziswa ngokuhlangana ne-lenalidomide (Revlimid) ne-dexamethasone ukwelapha i-myeloma eminingi (umdlavuza wamangqamuzana e-plasma emnkantsheni wethambo) osekubi kakhulu ngemuva kokwelashwa ngeminye imithi ye-chemotherapy. U-Ixazomib usesigabeni semithi ebizwa nge-proteasome inhibitors. Isebenza ngokusiza ukubulala amangqamuzana omdlavuza.

U-Ixazomib uza njenge-capsule ezothathwa ngomlomo. Imvamisa ithathwa ngamanzi esiswini esingenalutho, okungenani ihora eli-1 ngaphambi noma amahora amabili ngemuva kokudla. Kuthathwa ngezinsuku eziyi-1,8, kanye ne-15 kumjikelezo wokwelashwa wezinsuku ezingama-28. Thatha ixazomib ngasikhathi sinye nsuku zonke oyithatha. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha ixazomib njengoba nje kuqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Ungathathi ixazomib ne-dexamethasone ngasikhathi sinye ngoba kufanele uthathe i-dexamethasone nokudla.

Gwinya wonke amaphilisi; ungawahlukanisi, ungawahlafune noma uwagxoze.

Qaphela lapho uphatha amaphilisi e-ixazomib. Ungavumeli isikhumba sakho, amehlo, umlomo, noma ikhala ukuthi kuhlangane namaphilisi we-ixazomib aphukile noma agayiwe. Uma ukuthintana okunjalo kwenzeka, geza isikhumba sakho kahle ngensipho namanzi noma ugeze amehlo akho kahle ngamanzi alula.

Uma uhlanza ngemuva kokuthatha ixazulula, ungaphindi umthamo. Thatha umthamo wakho olandelayo we-ixazomib ngosuku olulandelayo oluhleliwe okufanele uluthathe.

Udokotela wakho kungadingeka ukuthi ayeke ukwelashwa kwakho okwesikhashana noma unomphela noma anciphise umthamo wakho we-ixazomib, noma eminye imithi oyiphuzayo, kuya ngemiphumela emibi oyitholayo. Qiniseka ukuthi ukhuluma nodokotela wakho mayelana nokuthi uzizwa kanjani ngesikhathi sokwelashwa kwakho. Ungayeki ukuthatha ixazomib ngaphandle kokukhuluma nodokotela wakho.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha ixazomib,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-ixazomib, noma imiphi eminye imithi, noma iziphi izithako ezikuma-capsule e-ixazomib. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela noma ongayinikiwe, amavithamini, izithako zokudla okunomsoco ozithathayo noma ohlela ukuzithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: carbamazepine (Epitol, Equetro, Carbatrol, Tegretol, Teril), efavirenz (Sustiva, e-Atripla), nevirapine (Viramune), phenobarbital, pioglitazone (Actos, e-Actoplus, Duetact, Oseni), phenytoin (I-Dilantin, i-Phenytek), i-rifabutin (i-Mycobutin), ne-rifampin (i-Rifadin, i-Rimactane, e-Rifamate, i-Rifater). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• utshele udokotela wakho ukuthi uthatha miphi imikhiqizo yamakhambi, ikakhulukazi iSt John's wort.
• utshele udokotela wakho uma uke waba nesifo sesibindi noma sezinso.
• utshele udokotela wakho uma ukhulelwe noma uhlela ukukhulelwa, noma uhlele ukuba nobaba wengane. Akufanele ukhulelwe ngenkathi uthatha ixazomib. Sebenzisa ukulawulwa kokubeletha okusebenzayo ngesikhathi sokwelashwa kwakho nge-ixazomib nezinsuku ezingama-90 ngemuva komthamo wakho wokugcina. Uma ungowesilisa futhi umlingani wakho angakhulelwa, kufanele usebenzise ukulawulwa kokubeletha okusebenzayo ngesikhathi sokwelashwa kwakho nezinsuku ezingama-90 ngemuva komthamo wakho wokugcina. Khuluma nodokotela wakho ngezindlela zokulawula ukubeletha ezizokusebenzela. Uma wena noma umlingani wakho ukhulelwa ngenkathi uthatha ixazomib, shayela udokotela wakho ngokushesha. Ixazomib ingalimaza umbungu.
• tshela udokotela wakho uma uncelisa. Akufanele uncelise ibele ngenkathi uthatha ixazulula.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula.Kodwa-ke, uma kungaphakathi kwamahora angama-72 (izinsuku ezi-3) zomthamo wakho olandelayo ohleliwe, weqa umthamo ongabanjwanga bese uqhubeka nesimiso sakho sokulinganisa ngokujwayelekile. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

Ixazomib ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isifo sohudo
• ukuqunjelwa
• isicanucanu
• ukuqhuma okusha noma okuba nzima
• ukuhlungu obusemhlane
• ukuvuvukala okungavamile kwezingalo noma imilenze yakho
• ukukhuluphala ngenxa yokuvuvukala
• ukungaboni kahle
• amehlo omile
• iso elibomvana

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu shayela udokotela wakho ngokushesha:

• isicanucanu
• ukukhathala ngokweqile
• ukulahlekelwa isifiso sokudla
• izimpawu ezinjengomkhuhlane
• ukopha okungajwayelekile noma ukulinyazwa
• ukuphuzi kwesikhumba sakho noma kwamehlo akho
• ubuhlungu engxenyeni engenhla yangakwesokudla yesisu sakho
• ukuvutha, ukushoshozela, ukuba ndikindiki, ubuhlungu, noma ubuthakathaka ezingalweni noma emilenzeni
• enegazi noma emnyama, isitulo sokulinda

Ixazomib ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese). Shiya umuthi emaphaketheni asekuqaleni kuze kube ngaphambi kokuwuthatha.

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ku-ixazomib.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• UNinlaro^®