Injection ye-Irinotecan Lipid Complex

-Delile

• Ngaphambi kokuthatha i-irinotecan lipid complex,
• I-Irinotecan lipid complex ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SEXWAYISO, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

Inkimbinkimbi ye-lipin ye-Irinotecan ingadala ukwehla okukhulu kwenani lamaseli amhlophe egazi enziwe ngomnkantsha wakho. Ukwehla kwenani lamaseli amhlophe egazi emzimbeni wakho kungandisa ubungozi bokuthi uzoba nokutheleleka okungathi sína. Udokotela wakho uzo-oda ukuhlolwa kwe-laboratory njalo ngesikhathi sokwelashwa kwakho ukubheka inani lamaseli amhlophe egazi egazini lakho. Ungaba sengozini enkulu yokuthola lo mphumela oseceleni uma ungowokuzalwa e-Asia. Uma uhlangabezana nalezi zimpawu ezilandelayo zokutheleleka, shayela udokotela wakho ngokushesha: umkhuhlane, amakhaza, umphimbo obuhlungu, ukukhwehlela okuqhubekayo nokucinana, noma ezinye izimpawu zokutheleleka.

I-Irinotecan lipid complex ingadala isifo sohudo esibi futhi esisongela impilo esingaholela ekuphelelweni amanzi emzimbeni. Tshela udokotela wakho uma uke waba nokuvinjelwa kwamathumbu noma ukuvimbela emathunjini akho. Ungahlangabezana nalezi zimpawu ezilandelayo kungakapheli amahora angama-24 ngemuva kokuthola i-irinotecan lipid complex: isifo sohudo (kwesinye isikhathi esibizwa ngokuthi "isifo sohudo sakuqala"), ikhala eligijimayo, amathe akhuphukile, abafundi abanciphayo (imibuthano emnyama phakathi kwamehlo), amehlo anamanzi, ukujuluka, ukugeleza , ukushaya kwenhliziyo okunciphile, noma amajaqamba esisu. Tshela udokotela wakho ngokushesha uma uhlangabezana nalezi zimpawu. Ungase futhi ube nohudo olunzima ngaphezu kwamahora angama-24 ngemuva kokuthola i-irinotecan lipid complex (kwesinye isikhathi ibizwa ngokuthi "isifo sohudo sekwephuzile"). Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo zohudo sekwedlule isikhathi, shayela udokotela wakho ngokushesha: isifo sohudo, ukuhlanza okukuvimba ekuphuzeni noma yini, indle emnyama noma enegazi, ikhanda elikhanyayo, isiyezi, noma ukuquleka. Udokotela wakho mhlawumbe uzokutshela ukuthi uthathe i-loperamide (Imodium AD) ukwelapha izimpawu zohudo sekwedlule isikhathi.

Khuluma nodokotela wakho ngezingozi zokuthola i-irinotecan lipid complex.

I-Irinotecan lipid complex isetshenziswa ngokuhlangana neminye imishanguzo yokwelapha umdlavuza we-pancreatic osabalele kwezinye izingxenye zomzimba eziye zaba nzima ngemuva kokwelashwa ngeminye imithi ye-chemotherapy. I-Irinotecan lipid complex isekilasini lemithi elwa namagciwane ebizwa nge-topoisomerase I inhibitors. Isebenza ngokumisa ukukhula kwamangqamuzana omdlavuza.

I-Irinotecan lipid complex iza njengoketshezi oluzofakwa ngaphakathi (emthanjeni) ngaphezu kwemizuzu engama-90 ngudokotela noma umhlengikazi esikhungweni sezokwelapha. Imvamisa inikezwa kanye njalo emavikini ama-2.

Udokotela wakho angadinga ukubambezela ukwelashwa kwakho futhi alungise umthamo wakho uma uhlangabezana nemiphumela ethile emibi. Qiniseka ukuthi utshela udokotela wakho ukuthi uzizwa kanjani ngenkathi welashwa nge-irinotecan lipid complex.

Udokotela wakho angakunika imithi yokuvikela isicanucanu nokuhlanza ngaphambi kokuthola umthamo ngamunye we-irinotecan lipid complex. Udokotela wakho angakunika noma akutshele ukuthi uthathe eminye imithi ukuvimbela noma ukwelapha eminye imiphumela emibi.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-irinotecan lipid complex,

• Tshela udokotela wakho kanye nosokhemisi uma une-irinotecan, noma imuphi omunye umuthi, noma iziphi izithako zomjovo we-irinotecan lipid. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho uma uthatha i-carbamazepine (Carbatrol, Equetro, Tegretol, Teril, Epitol), phenobarbital, phenytoin (Dilantin, Phenytek), rifabutin (Mycobutin), rifampin (Rifadin, Rimactane, in Rifamate, Rifap, ). Udokotela wakho mhlawumbe uzokutshela ukuthi ungayithathi le mithi okungenani amasonto ama-2 ngaphambili, nangesikhathi sokwelashwa kwakho nge-irinotecan lipid complex. Tshela udokotela wakho uma uthatha i-clarithromycin (Biaxin, e-Prevpac), indinavir (Crixivan), itraconazole (Onmel , Sporanox), ketoconazole, lopinavir (eKaletra), nefazodone, nelfinavir (Viracept), ritonavir (Norvir, eKaletra, Viekira Pak), saquinavir (Invirase), telaprevir (Incivek), ne-voriconazole (Vfend). Udokotela wakho mhlawumbe uzokutshela ukuthi ungayithathi le mithi okungenani isonto elilodwa ngaphambili, nangesikhathi sokwelashwa kwakho nge-irinotecan lipid complex.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunomsoco, okwenzayo noma ohlela ukukuthatha. Qiniseka ukuthi uyayisho imishanguzo ebhalwe ngenhla nokunye okulandelayo: i-atazanavir (Reyataz, e-Evotaz) ne-gemfibrozil (Lopid). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo eminingi ingaxhumana ne-irinotecan lipid complex, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulezi zinhlu.
• utshele udokotela wakho ukuthi uthatha miphi imikhiqizo yamakhambi, ikakhulukazi iSt John's wort. Udokotela wakho mhlawumbe uzokutshela ukuthi ungathathi i-wort yaseSt.John okungenani amasonto ama-2 ngaphambili, nangesikhathi sokwelashwa kwakho nge-irinotecan lipid complex.
• utshele udokotela wakho uma uke waba nesifo sesibindi noma sezinso.
• utshele udokotela wakho uma ukhulelwe noma uhlela ukukhulelwa, noma uhlele ukuba nobaba wengane. Akufanele ukhulelwe ngenkathi uthola i-irinotecan lipid complex kanye nenyanga e-1 ngemuva kokuthola ukwelashwa kwakho kokugcina. Sebenzisa indlela ethembekile yokulawula ukubeletha ngesikhathi sokwelashwa kwakho nenyanga e-1 ngemuva kokwelashwa kwakho kokugcina. Uma ungowesilisa futhi umlingani wakho angakhulelwa, kufanele usebenzise ukulawulwa kokubeletha ngenkathi uthola lo muthi, futhi izinyanga ezine ngemuva kokwelashwa kwakho kokugcina. Khuluma nodokotela wakho ngezindlela zokulawula ukubeletha ezizokusebenzela. Uma wena noma umlingani wakho ukhulelwa ngenkathi uthola i-irinotecan lipid complex, shayela udokotela wakho ngokushesha. Irinotecan lipid complex ingalimaza umbungu.
• tshela udokotela wakho uma uncelisa. Udokotela wakho angakutshela ukuthi ungancelisi ibele ngesikhathi sokwelashwa kwakho nenyanga e-1 ngemuva kokwelashwa kwakho kokugcina.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

I-Irinotecan lipid complex ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ukukhathala okungajwayelekile noma ubuthakathaka
• ukuncipha kokudla
• isicanucanu
• ukuvuvukala noma izilonda emlonyeni
• ukulahleka kwezinwele

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SEXWAYISO, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukuqubuka
• ukulunywa
• isifuba
• ukuqina kwesifuba noma ubuhlungu
• isifuba
• ukukhwehlela okusha noma okuba kubi kakhulu
• ukuvuvukala kobuso, umphimbo, ulimi, izindebe, noma amehlo
• ukuphefumula kanzima noma ukugwinya
• indawo yesikhumba esibomvu, esifudumele, esibuhlungu, noma esivuvukele eduze kwendawo lapho umjovo wafakwa khona
• ukuhlanza
• ukuncipha kokuchama
• ukuvuvukala kwemilenze nezinyawo
• isiyezi
• ukuphelelwa umoya
• ukopha okungajwayelekile noma ukulinyazwa

I-Irinotecan lipid complex ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri.

Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana ne-irinotecan lipid complex.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Onivyde^®