I-Lesinurad

-Delile

• Ngaphambi kokuthatha i-lesinurad,
• I-Lesinurad ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe ezingxenyeni EZIBALULEKILE ZESixwayiso, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

I-Lesinurad ingadala izinkinga ezinkulu zezinso. Tshela udokotela wakho uma welashwa nge-dialysis (ukwelashwa ukuhlanza igazi lapho izinso zingasebenzi kahle), uthole ukufakelwa izinso, noma uke waba nesifo sezinso noma wake waba naso. Ingozi yokuthi uzoba nezinkinga ezinkulu zezinso inkulu uma uthatha i-lesinurad wedwa. I-Lesinurad kumele ithathwe ihlanganiswe ne-xanthine oxidase inhibitor efana ne-allopurinol (Lopurin, Zyloprim) noma i-febuxostat (Uloric). Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: isicanucanu, ukuhlanza, noma ubuhlungu besisu sangaphezulu ngakwesokudla.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho angalawula izivivinyo ezithile ngaphambi nangesikhathi sokwelashwa ukuze ahlole impendulo yomzimba wakho ku-lesinurad.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa nge-lesinurad futhi isikhathi ngasinye lapho ugcwalisa umuthi wakho. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) ukuthola uMhlahlandlela Wezokwelapha.

I-Lesinurad isetshenziswa ngokuhlangana ne-xanthine oxidase inhibitor ukwelapha i-hyperuricemia (amazinga aphezulu e-uric acid) kubantu abane-gout (ukuhlaselwa okungazelelwe kokubomvu, ukuvuvukala, ubuhlungu, nokushisa kwilunga elilodwa noma ngaphezulu) isifo sabo esingalawulwa namanje imithi. I-Lesinurad isekilasini lemithi ebizwa ngokuthi i-uric acid reabsorption inhibitors ekhethiwe. Isebenza ngokusiza izinso ukususa i-uric acid emzimbeni.

I-Lesinurad iza njengethebhulethi ezothathwa ngomlomo. Imvamisa kuthathwa kanye nsuku zonke ekuseni ngokudla namanzi. Thatha i-lesinurad ngasikhathi sinye nsuku zonke futhi ngasikhathi sinye lapho uthatha i-xanthine oxidase inhibitor efana ne-allopurinol (Lopurin, Zyloprim) noma i-febuxostat (Uloric). Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-lesinurad njengoba nje iyalelwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

I-Lesinurad ilawula i-hyperuricemia kubantu abane-gout kodwa ayiyelaphi. I-gout yakho ingahle iqhume (ukuhlangana okubuhlungu okukhulu, ukuvuvukala) lapho uqala ukuthatha i-lesinurad, kepha ungayeki ukuyithatha. Udokotela wakho uzokunika eminye imithi yokusiza ukuvimbela ukuqhuma kwama-gout. Qhubeka uthathe i-lesinurad noma ngabe uzizwa uphilile noma uhlaselwa yi-gout. Ungayeki ukuthatha i-lesinurad ngaphandle kokukhuluma nodokotela wakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-lesinurad,

• Tshela udokotela wakho kanye nosokhemisi uma une-allergies ku-lesinurad, noma imuphi omunye umuthi, noma iziphi izithako ezikumaphilisi e-lesinurad. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: amiodarone (Cordarone, Nexterone, Pacerone), amlodipine (Norvasc), aspirin, carbamazepine (Epitol, Equetro, Teril, others), fluconazole (Diflucan), rifampin (Rifadin, Rimactane, in Rifamate, kuRifater), sildenafil (Revatio, Viagra), noma i-valproic acid (Depakene). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo eminingi ingaxhumana ne-lesinurad, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho nalawo angaveli kulolu hlu.
• Tshela udokotela wakho uma ngabe uke waba nanoma yiziphi zezimo ezishiwo esigabeni ESIBALULEKILE SESEXWAYISO, i-tumor lysis syndrome (isimo esibangela ukuthi amangqamuzana omdlavuza aphule ngokushesha futhi akhiphe imikhiqizo egazini), noma i-Lesch-Nyhan syndrome (i isifo esizuzwe njengefa esidala amazinga aphezulu e-uric acid egazini). Udokotela wakho mhlawumbe uzokutshela ukuthi ungathathi i-lesinurad.
• utshele udokotela wakho uma uke wahlaselwa isifo sohlangothi, wahlaselwa yinhliziyo, umfutho wegazi ophakeme, isifo senhliziyo, i-cholesterol ephezulu, noma isifo sesibindi.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Izindlela zokuvimbela inzalo zeHormonal (amaphilisi okulawula ukubeletha, amabala, izindandatho, isibhamu, okufakelwa kanye namadivayisi we-intrauterine) kungenzeka angasebenzi kahle uma esetshenziswa ne-lesinurad futhi akufanele isetshenziswe njengendlela yakho kuphela yokulawula ukubeletha. Khuluma nodokotela wakho ngezindlela zokulawula ukubeletha ezizokusebenzela. Uma ukhulelwa ngenkathi uthatha i-lesinurad, shayela udokotela wakho.

Phuza okungenani ama-ounces ama-68 (amalitha amabili) wamanzi noma olunye uketshezi njalo emahoreni angama-24 ngenkathi uthatha i-lesinurad ngaphandle kokuthi uqondiswe ngenye indlela ngudokotela wakho.

Uma uphuthelwa ukuthatha i-lesinurad ekuseni, ungayibeki ngemuva kosuku. Qhubeka nesimiso sakho sokulinganisa okujwayelekile ngakusasa ngokudla namanzi. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Lesinurad ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• izimpawu ezinjengomkhuhlane njengekhanda, umkhuhlane, ukujuluka, ubuhlungu bemisipha nokukhathala
• isilungulela

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe ezingxenyeni EZIBALULEKILE ZESixwayiso, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ubuhlungu besifuba, ingcindezi, noma ukungaphatheki kahle
• ukuphelelwa umoya noma ukuphefumula kanzima
• ubuthakathaka engxenyeni eyodwa noma ohlangothini lomzimba wabo
• inkulumo engahambi kahle

I-Lesinurad ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Ukugcine ekamelweni lokushisa kude nokukhanya, ukushisa okweqile nomswakama (hhayi endlini yangasese).

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Zurampic^®