Inaliti ye-Daclizumab

-Delile

• Ngaphambi kokusebenzisa umjovo we-daclizumab,
• Umjovo we-Daclizumab ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SEXWAYISO, bese ushayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

Umjovo we-Daclizumab awusatholakali. Uma njengamanje usebenzisa i-daclizumab, kufanele ushayele udokotela wakho ukuze axoxe ngokushintshela kolunye ukwelashwa.

I-Daclizumab ingadala ukulimala kwesibindi okungathi sína noma okusongela ukuphila. Ingozi yokulimala kwesibindi ingakhuphuka kubantu abathatha eminye imishanguzo eyaziwa ngokudala ukulimala kwesibindi, nakubantu asebavele benesifo sesibindi. Tshela udokotela wakho uma uke waba nezinkinga zesibindi noma i-hepatitis. Udokotela wakho angakutshela ukuthi ungasebenzisi umjovo we-daclizumab. Tshela udokotela wakho kanye nosokhemisi ngayo yonke imithi oyiphuzayo ukuze bakwazi ukubheka ukuthi ngabe ikhona yini imishanguzo yakho engakhuphula ubungozi bokuthi uzoba nokulimala kwesibindi ngesikhathi ukwelashwa kwakho nge-daclizumab. Udokotela wakho uzokuqapha ngezimpawu zezinkinga zesibindi ngesikhathi nangezinyanga eziyi-6 ngemuva kokwelashwa kwakho nge-daclizumab. Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: isicanucanu, ukuhlanza, ukukhathala ngokweqile, ukopha okungavamile noma ukulimaza, ukungabi namandla, ukulahlekelwa isifiso sokudla, ubuhlungu engxenyeni engenhla kwesokudla yesisu, ukuphuzi kwesikhumba noma kwamehlo , umchamo onombala omnyama, noma izimpawu ezifana nomkhuhlane.

I-Daclizumab ingadala ukuphazamiseka okukhulu kwamasosha omzimba (izimo ezenzeka lapho amasosha omzimba ehlasela amaseli anempilo emzimbeni). Tshela udokotela wakho uma uke waba nezinkinga zesikhumba noma owake waba nazo, kufaka phakathi i-eczema noma i-psoriasis. Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: ukubomvu, ukulunywa, noma ukukala kwesikhumba; izindlala ezivuvukile entanyeni, emakhwapheni, noma emgodini; isifo sohudo; indle enegazi; ubuhlungu besisu; noma yiluphi uphawu olusha, olungachazwanga oluthinta noma iyiphi ingxenye yomzimba wakho.

Ngenxa yezingozi zalo muthi, umjovo we-daclizumab utholakala kuphela ngohlelo olukhethekile lokusabalalisa olukhawulelwe. Uhlelo selusungulwe ngumenzi we-daclizumab ukuze aqiniseke ukuthi abantu abayisebenzisi i-daclizumab injection ngaphandle kokuqapha okudingekayo okubizwa ngeZinbryta Risk Evaluation and Mitigation Strategies (REMS) Programme. Udokotela wakho kanye nosokhemisi wakho kumele babhaliswe nohlelo lweZinbryta REMS. Buza udokotela wakho ukuthola eminye imininingwane ngalolu hlelo nokuthi uzoyithola kanjani imithi yakho.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile ngaphambi, ngesikhathi, nangezinyanga eziyi-6 ngemuva komthamo wakho wokugcina ukuze ahlole impendulo yomzimba wakho kumjovo we-daclizumab.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa ngomjovo we-daclizumab futhi isikhathi ngasinye lapho ugcwalisa umuthi wakho. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) ukuthola uMhlahlandlela Wezokwelapha.

Khuluma nodokotela wakho ngobungozi (s) bokuthola umjovo we-daclizumab.

I-Daclizumab isetshenziselwa ukuvimbela iziqephu zezimpawu futhi yehlise ukwanda kokukhubazeka kubantu abanamafomu okubuyisela emuva (izifo zesifo lapho izimpawu zivela khona ngezikhathi ezithile) ze-multiple sclerosis (MS; isifo lapho izinzwa zingasebenzi khona kahle futhi abantu bangathola ubuthakathaka, ukuba ndikindiki, ukulahleka kokuxhumanisa kwemisipha, nezinkinga ngombono, ukukhuluma, nokulawula isinye). I-Daclizumab ivame ukusetshenziswa ngabantu abangazange basizwe okungenani eminye imithi emibili ye-MS. UDaclizumab usesigabeni semithi ebizwa ngama-immunomodulators. Kucatshangwa ukuthi kusebenza ngokunciphisa ukuvuvukala nokunciphisa isenzo samaseli omzimba angadala ukulimala kwezinzwa.

IDaclizumab iza njengesisombululo (uketshezi) kusirinji ekhethiwe ukujova ngomgogodla (ngaphansi kwesikhumba). Kuvame ukujova kanye ngenyanga. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Sebenzisa i-daclizumab njengoba nje kuqondisiwe. Ungayisebenzisi ngaphezulu noma ngaphansi kwayo noma uyisebenzise kaningi kunokuyalelwa ngudokotela wakho.

Uzothola umthamo wakho wokuqala we-daclizumab ehhovisi likadokotela wakho. Ngemuva kwalokho, ungazifaka i-daclizumab ngokwakho noma umngane noma isihlobo senze imijovo. Ngaphambi kokusebenzisa i-daclizumab ngokwakho okokuqala, funda imiyalo ebhaliwe eza nayo. Buza udokotela wakho noma usokhemisi ukuthi akubonise noma umuntu ozobe ejova umuthi ukuthi ungawujova kanjani.

Ungafaka i-daclizumab ngemuva kwezingalo zakho ezingaphezulu, indawo yesisu, noma amathanga akho. Ungafaki umuthi wakho esikhumbeni esicasukile, esilimele, esibomvu, esingenwe yigciwane, esibaziweyo noma esibhalwe emzimbeni.

Ungalokothi uphinde usebenzise noma wabelane ngezinaliti noma imijovo ekhethiwe yemithi. Phonsa imijovo esetshenzisiwe esitsheni esingamelana nokubhoboza. Khuluma nodokotela wakho noma usokhemisi mayelana nokuthi ungasilahla kanjani isitsha esingamelana nokubhoboza.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokusebenzisa umjovo we-daclizumab,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-daclizumab, noma imiphi eminye imithi, noma yiziphi izithako zomjovo we-daclizumab. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• Tshela udokotela wakho uma uke waba nesifo sofuba noma wake waba nesifo. Futhi, tshela udokotela wakho uma uke waba nokudangala noma wake wacabanga noma wazama ukuzibulala.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi usebenzisa i-daclizumab, shayela udokotela wakho.
• kufanele wazi ukuthi ungahle ucindezeleke noma uzibulale (ucabanga ngokuzilimaza noma ukuzibulala noma ukuhlela noma ukuzama ukwenza kanjalo) ngenkathi usebenzisa umjovo we-daclizumab. Wena, umndeni wakho, noma umnakekeli wakho kufanele ushayele udokotela wakho ngokushesha uma uhlangabezana nalezi zimpawu ezilandelayo: ukucindezeleka okusha noma okuya kuba kubi, ukukhuluma noma ukucabanga ngokufuna ukuzilimaza noma ukuqeda impilo yakho, noma ezinye izinguquko ezingajwayelekile ekuziphatheni noma emoyeni . Qiniseka ukuthi umndeni wakho noma umnakekeli wakho uyazi ukuthi yiziphi izimpawu ezingaba zimbi kakhulu ukuze bakwazi ukubiza udokotela uma ungakwazi ukuzifunela ukwelashwa wedwa.
• awunayo imigomo ngesikhathi sokwelashwa kwakho nge-daclizumab noma kufika ezinyangeni ze-4 ngemuva komthamo wakho wokugcina ngaphandle kokukhuluma nodokotela wakho.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Uma uphuthelwa umthamo womjovo we-daclizumab, jovela umthamo wakho olahlekile ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma kungaphezu kwamasonto ama-2 ngemuva kokwehla kwedosi yakho, weqa umthamo ophuthelwe bese uqhubeka nesimiso sakho sokulinganisa. Musa ukujova umthamo ophindwe kabili ukwenzela umthamo ongabanjwanga. Shayela udokotela wakho uma uphuthelwa umthamo futhi unemibuzo mayelana nokuthi wenzeni.

Umjovo we-Daclizumab ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• induna
• ubuhlungu bomlomo

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SEXWAYISO, bese ushayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukuqubuka
• isifuba
• ukulunywa
• ukuphefumula kanzima noma ukugwinya
• ukuvuvukala kwamehlo, ubuso, umlomo, ulimi, noma umphimbo
• ukucindezeleka okusha noma okuya kuba kubi
• ushintsho esimweni sengqondo noma ekuziphatheni
• ukucabanga ngokuzilimaza noma ukuzibulala noma ukuhlela noma ukuzama ukwenza kanjalo
• ukuphuma kwamakhala, ukukhwehlela, umphimbo obuhlungu, umkhuhlane, ukugodola nezinye izimpawu zokutheleleka
• ubunzima bokuchama
• ubuhlungu lapho uchama
• isithuthwane

I-Daclizumab ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi ebhokisini efike kuyo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina i-daclizumab esiqandisini kodwa ungayifaki iqhwa. Uma ufaka umuthi ngephutha, kufanele ulahle lo mjovo. I-Daclizumab ingagcinwa ekamelweni lokushisa izinsuku ezingama-30 kepha kufanele ivikelwe ekukhanyeni. IDaclizumab akufanele ibuyiselwe esiqandisini ngemuva kokuthi igcinwe ekamelweni lokushisa.

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Ngaphambi kokwenza noma yiluphi uvivinyo lwelabhoratri, tshela udokotela wakho kanye nabasebenzi belebhuthi ukuthi usebenzisa umjovo we-daclizumab.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

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• IZenapax^®¶

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