I-Rucaparib

-Delile

• Ngaphambi kokuthatha i-rucaparib,
• I-Rucaparib ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

I-Rucaparib isetshenziselwa ukusiza ukugcina impendulo kwezinye izindlela zokwelashwa zezinhlobo ezithile zomdlavuza wesibeletho (umdlavuza oqala ezithweni zokuzala zabesifazane lapho kwakhiwa khona amaqanda), ishubhu lesisu (ishubhu elihambisa amaqanda akhishwe ama-ovari liye esibelethweni), futhi okuyinhloko I-peritoneal (ungqimba lwezicubu ezibeka isisu) umdlavuza obuyile kubantu abadala abaphendule ngokuphelele noma abaphendule ngokwengxenye kolunye ukwelashwa ngamakhemikhali. Ibuye isetshenziselwe ukwelapha izinhlobo ezithile zomdlavuza we-ovari, umdlavuza we-fallopian tube, nomdlavuza oyinhloko we-peritoneal kubantu abanegciwane elithile abathole ukwelashwa okungenani ngezinye izindlela ezimbili zokwelashwa ngamakhemikhali. I-Rucaparib ibuye isetshenziselwe ukwelapha izinhlobo ezithile zomdlavuza wendlala yesinye eye yasabalala kwezinye izindawo emzimbeni kubantu abanegciwane elithile abathole ezinye izindlela zokwelashwa. URucaparib usesigabeni semithi ebizwa nge-poly (ADP-ribose) polymerase (PARP) inhibitors. Isebenza ngokubulala amangqamuzana omdlavuza.

URucaparib uza njengethebhulethi ukuthatha ngomlomo. Imvamisa kuthathwa ngokudla noma ngaphandle kokudla kabili ngosuku, cishe amahora angama-12 ahlukene. Thatha i-rucaparib ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-rucaparib njengoba iqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Udokotela wakho angadinga ukubambezela ukwelashwa kwakho noma alungise umthamo wakho we-rucaparib ngokuya ngempendulo yakho ekwelashweni nanoma yimiphi imiphumela emibi ohlangabezana nayo. Khuluma nodokotela wakho mayelana nokuthi uzizwa kanjani ngesikhathi sokwelashwa kwakho. Ungayeki ukuthatha i-rucaparib ngaphandle kokukhuluma nodokotela wakho.

Uma uhlanza ngemuva kokuthatha i-rucaparib, ungathathi omunye umthamo. Qhubeka nesimiso sakho sokulinganisa okuvamile.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-rucaparib,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-rucaparib, noma imuphi omunye umuthi, noma iziphi izithako ezibhebheni ze-rucaparib. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunomsoco, okwenzayo noma ohlela ukukuthatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: warfarin (Coumadin, Jantoven). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo eminingi ingaxhumana ne-rucaparib, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uhlele ukuba nobaba wengane. Akufanele ukhulelwe ngenkathi uthatha i-rucaparib. Uzodinga ukwenza ukuhlolwa kokukhulelwa ngaphambi kokuqala ukwelashwa. Sebenzisa ukulawulwa kokubeletha okusebenzayo ngesikhathi sokwelashwa kwakho nge-rucaparib nangezinyanga eziyisithupha ngemuva komthamo wakho wokugcina. Uma ungowesilisa, wena nomlingani wakho wesifazane kufanele nisebenzise ukulawulwa kokubeletha ngesikhathi sokwelashwa futhi izinyanga ezintathu ngemuva komthamo wakho wokugcina. Khuluma nodokotela wakho ngezindlela zokulawula ukubeletha ezizokusebenzela. Uma ukhulelwa ngenkathi uthatha i-rucaparib, shayela udokotela wakho.
• tshela udokotela wakho uma uhlela ukuncelisa. Akufanele uncelise ngesikhathi sokwelashwa kwakho nge-rucaparib kanye namasonto ama-2 ngemuva komthamo wakho wokugcina.
• hlela ukugwema ukuvezwa yilanga ngokungadingekile noma isikhathi eside futhi ugqoke izingubo zokuzivikela, isigqoko, izibuko zelanga, nezigcobo zelanga. I-Rucaparib ingenza isikhumba sakho sizwele ekukhanyeni kwelanga.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Yeqa umthamo ophuthelwe bese uqhubeka nesimiso sakho sokulinganisa esivamile. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Rucaparib ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isicanucanu
• ukuhlanza
• ukuqunjelwa
• isifo sohudo
• ubuhlungu besisu
• ukulahlekelwa isifiso sokudla
• ukunambitheka okubi emlonyeni
• ukulunywa
• izilonda zomlomo
• ukuminyana kwamakhala, ikhala eligobayo, ukuthimula, umphimbo obuhlungu noma onwaya, noma ukukhwehlela

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

• ubuthakathaka, ukukhathala, umkhuhlane, ukunciphisa umzimba, ukulimaza noma ukopha kalula, noma igazi emchameni noma esitulweni
• isikhumba esiphaphathekile
• ukuphelelwa umoya
• ukuqubuka

I-Rucaparib ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ngaphambi kokuthi uqale futhi ngezikhathi ezahlukahlukene kulo lonke ukwelashwa kwakho ukuze uhlole impendulo yomzimba wakho ku-rucaparib. Kwezinye izimo, udokotela wakho uzokuyalela ukuhlolwa kwelebhu ngaphambi kokuba uqale ukwelashwa kwakho ukuze ubone ukuthi umdlavuza wakho ungelashwa nge-rucaparib.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Rubraca^®