I-Niraparib

-Delile

• Ngaphambi kokuthatha i-niraparib,
• I-Niraparib ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

I-Niraparib isetshenziselwa ukusiza ukugcina ukuphendula kwezinhlobo ezithile zama-ovarian (izitho zokuzala zabesifazane lapho kwakhiwa khona amaqanda), ishubhu le-fallopian (ishubhu elihambisa amaqanda akhishwe ama-ovari liye esibelethweni), kanye ne-peritoneal (ungqimba lwezicubu ezihambisa isisu) umdlavuza kubantu abaphendule ngokuphelele noma abaphendule kancane kweminye imithi (i) yamakhemikhali. Ibuye isetshenziselwe ukwelapha izinhlobo ezithile zomdlavuza we-ovari, i-fallopian, noma i-peritoneal lapho umdlavuza usukhule kakhulu ngemuva kokwelashwa kwamakhemikhali ama-3 noma ngaphezulu. INiraparib isekilasini lemithi ebizwa nge-poly (ADP-ribose) polymerase (PARP) inhibitors. Isebenza ngokubulala amangqamuzana omdlavuza.

INiraparib iza njengephilisi elizothathwa ngomlomo kanye nsuku zonke. Thatha i-niraparib ngasikhathi sinye nsuku zonke noma ngaphandle kokudla. Uma uhlangabezana nesicanucanu ngemuva kokuthatha i-niraparib, yithathe kanye ngosuku ngesikhathi sokulala. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-niraparib njengoba iqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Gwinya wonke amaphilisi; ungazivuli, uzihlafune noma uziqede.

Uma uhlanza ngemuva kokuthatha i-niraparib, ungathathi omunye umthamo. Qhubeka nesimiso sakho sokulinganisa okuvamile.

Udokotela wakho anganciphisa umthamo wakho we-niraparib, noma ayeke unomphela noma okwesikhashana ukwelashwa kwakho, uma uhlangabezana nemiphumela ethile emibi. Qiniseka ukuthi utshela udokotela wakho ukuthi uzizwa kanjani ngesikhathi sokwelashwa kwakho nge-niraparib.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-niraparib,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-niraparib, noma imuphi omunye umuthi, noma yiziphi izithako ezikuma-capsule e-niraparib. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• Tshela udokotela wakho uma ngabe uke waba ne-arrhythmias (isigqi senhliziyo esingajwayelekile), umfutho wegazi ophakeme, noma isifo senhliziyo.
• utshele udokotela wakho uma ukhulelwe noma uhlela ukukhulelwa. Uzodinga ukuhlolwa kokukhulelwa okungekuhle ngaphambi kokuqala ukwelashwa futhi kufanele usebenzise ukulawulwa kokuzalwa ukuvimbela ukukhulelwa ngesikhathi sokwelashwa kwakho nezinyanga eziyisithupha ngemuva komthamo wakho wokugcina we-niraparib. Khuluma nodokotela wakho ngezindlela zokulawula ukubeletha ezizokusebenzela. Uma ukhulelwa ngenkathi uthatha i-niraparib, shayela udokotela wakho ngokushesha. INiraparib ingalimaza umbungu.
• tshela udokotela wakho uma uncelisa noma uhlela ukuncelisa. Akufanele uncelise ngenkathi uthatha i-niraparib kanye nenyanga engu-1 ngemuva komthamo wakho wokugcina.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Yeqa umthamo ophuthelwe bese uqhubeka nesimiso sakho sokulinganisa esivamile. Ungathathi umthamo ophindwe kabili ukwenzela umthamo ophuthelwe.

I-Niraparib ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isicanucanu
• ukuhlanza
• ukuqunjelwa
• isilungulela
• umlomo owomile
• izilonda emlonyeni
• ukulahlekelwa isifiso sokudla
• ukuhlungu obusemhlane
• ikhanda
• isiyezi
• izinguquko ekunambithekeni
• ubunzima bokulala noma ukulala
• ukukhathazeka
• ukuqubuka

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

• isikhumba esiphaphathekile
• ukuphelelwa umoya
• ubuthakathaka
• ukukhathala
• ukuncipha komzimba
• ukulimaza noma ukopha kalula
• igazi emchameni noma esitulweni
• umuzwa ovuthayo lapho uchama
• kaningi noma ngokuphuthumayo isidingo sokuchama
• umkhuhlane, ukukhwehlela, ukuphuma kwamakhala, noma ezinye izimpawu zokutheleleka

INiraparib ingakhuphula ubungozi bokuthi uzoba neminye imidlavuza. Khuluma nodokotela wakho ngale ngozi.

INiraparib inganciphisa ukuzala emadodeni. Khuluma nodokotela wakho ngezingozi zokuthatha i-niraparib.

I-Niraparib ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzohlola umfutho wegazi lakho njalo futhi a-oda izivivinyo ezithile zelebhu ngaphambi nangesikhathi sokwelashwa kwakho ukuze ahlole impendulo yomzimba wakho ku-niraparib.

Kwezinye izimo, i-niraparib ingasetshenziswa kuphela kubantu abanokwakheka okuthile kofuzo. Udokotela wakho angalawula ukuhlolwa kwegazi ukusiza ukunquma ukuthi le mithi ikulungele yini.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• UZejula^®