I-Abacavir, iDolutegravir, neLamivudine

-Delile

• I-Abacavir, i-dolutegravir, ne-lamivudine kungadala ukusabela okweqile noma okusongela impilo. Shayela udokotela wakho ngokushesha uma uba nesifo esisodwa kumaqembu amabili noma ngaphezulu kulawa alandelayo ukuze ubone ukuthi kufanele uyeke ukuthatha i-abacavir, i-dolutegravir, ne-lamivudine:
• Ngaphambi kokuthatha i-abacavir, i-dolutegravir, ne-lamivudine,
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalezi zimpawu ezilandelayo, noma lezo ezishiwo esigabeni ESIBALULEKILE SEXWAYISO, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

I-Abacavir, i-dolutegravir, ne-lamivudine kungadala ukusabela okweqile noma okusongela impilo. Shayela udokotela wakho ngokushesha uma uba nesifo esisodwa kumaqembu amabili noma ngaphezulu kulawa alandelayo ukuze ubone ukuthi kufanele uyeke ukuthatha i-abacavir, i-dolutegravir, ne-lamivudine:

• Iqembu 1: umkhuhlane
• Iqembu 2: ukuqubuka
• Iqembu 3: isicanucanu, ukuhlanza, isifo sohudo, noma ubuhlungu bendawo yesisu
• Iqembu 4: ukugula ngokuvamile, ukukhathala ngokweqile, noma ukukhathazeka
• Iqembu 5: ukuphefumula, ukukhwehlela, noma umphimbo obuhlungu

Futhi, shayela udokotela wakho ngokushesha uma uhlangabezana nalezi zimpawu ezilandelayo: ikhanda; ubuhlungu bemisipha noma obuhlangene; ukuvuvukala kobuso, izandla, izinyawo, amaqakala, noma imilenze engezansi; ubuhlungu, ukushisa, noma ukuhayiza ezandleni noma ezinyaweni; ukulunywa; ukushwabana noma ukuxebuka kwesikhumba; ubunzima bokugwinya noma ukuphefumula; amehlo abomvu, avuvukile, alumayo noma anezinyembezi; noma izilonda emlonyeni.

Usokhemisi wakho uzokunikeza ikhadi lesixwayiso lapho uthola imishanguzo azokuphatha. Ikhadi Lesixwayiso liqukethe amaqembu ezimpawu abhalwe ngenhla ukwenza kube lula kuwe nakubantu abakuzungezile ukuthi babone uma unezinto ezingezwani neze. Qiniseka ukuthi uphatha leli Khadi Lesixwayiso ngaso sonke isikhathi.

Abanye abantu bangase babe nethuba lokungazwani ne-abacavir, i-dolutegravir, ne-lamivudine ngokuya ngofuzo lwabo noma ukwakheka kofuzo. Udokotela wakho angalawula ukuhlolwa kwelebhu yezakhi zofuzo ngaphambi kokuqala i-abacavir, i-dolutegravir, ne-lamivudine noma uma ungazange uhlolwe ngaphambilini ukuthola ukuthi kungenzeka yini ukuthi uthola ukungahambi kahle kulo muthi. Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-abacavir, i-dolutegravir, ne-lamivudine noma eminye imishanguzo equkethe i-abacavir noma i-dolutegravir noma uma wazi ukuthi unaleyo ndlela yokwakheka kofuzo.Uma ngabe uke waba nokungezwani nokwedlule ku-abacavir (e-Epzicom, ku-Trizivir, Ziagen) noma kwi-dolutegravir (Tivicay) noma yimuphi omunye umuthi oqukethe i-abacavir noma i-dolutegravir, udokotela wakho mhlawumbe uzokutshela ukuthi ungathathi i-abacavir, i-dolutegravir, ne-lamivudine. Uma udokotela wakho ekutshela ukuthi uyeke ukuthatha i-abacavir, i-dolutegravir, ne-lamivudine ngoba unegciwane, ungalokothi uthathe i-abacavir, i-dolutegravir, ne-lamivudine noma umuthi one-abacavir noma i-dolutegravir futhi. Uma uyeka ukuthatha i-abacavir, i-dolutegravir, ne-lamivudine nganoma yisiphi esinye isizathu, kufaka phakathi ukuphuthelwa imithamo eminingi ilandelana noma ukuphelelwa yimithi, ungaqali ukuyithatha futhi ngaphandle kokukhuluma nodokotela wakho kuqala. Uzodinga ukuba seduze nabantu abangakunikeza noma abafonele usizo lwezempilo oluphuthumayo, uma kudingeka, lapho uqala kabusha lo muthi.

Tshela udokotela wakho uma une noma ucabanga ukuthi ungaba nokutheleleka ngegciwane le-hepatitis B (HBV; ukutheleleka kwesibindi okuqhubekayo) noma ukutheleleka ngegciwane le-hepatitis C (HCV; ukutheleleka kwesibindi okuqhubekayo). Uma une-HBV futhi uthatha i-abacavir, i-dolutegravir, ne-lamivudine, isimo sakho singase sibe sibi ngokungazelelwe lapho uyeka ukuthatha i-abacavir, i-dolutegravir, ne-lamivudine. Udokotela wakho uzokuhlola futhi a-oda izivivinyo zebhu njalo ezinyangeni ezimbalwa ngemuva kokuyeka ukuthatha i-abacavir, i-dolutegravir, ne-lamivudine ukuze ubone ukuthi i-HBV yakho isiye yanda yini.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile ukuze ahlole impendulo yomzimba wakho ku-abacavir, i-dolutegravir, ne-lamivudine.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wokwelashwa) lapho uqala ukwelashwa nge-abacavir, i-dolutegravir, ne-lamivudine futhi isikhathi ngasinye lapho ugcwalisa umuthi wakho. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) noma iwebhusayithi yomkhiqizi ukuthola i-Medication Guide.

Khuluma nodokotela wakho ngezingozi zokuthatha i-abacavir, i-dolutegravir, ne-lamivudine.

Inhlanganisela ye-abacavir, i-dolutegravir, ne-lamivudine isetshenziswa yodwa noma neminye imithi yokwelapha ukutheleleka nge-HIV kubantu abadala abathile nezingane ezinesisindo okungenani esingu-88 lb (40 kg). I-Abacavir ne-lamivudine basesigabeni semithi ebizwa nge-nucleoside analogue reverse transcriptase inhibitors (NRTIs) kanti i-dolutegravir ikusigaba semithi esibizwa nge-integrase strand transfer inhibitors (INSTIs). Zisebenza ngokunciphisa inani le-HIV egazini lakho nokwandisa inani lamaseli omzimba asiza ukulwa nezifo emzimbeni wakho. Yize i-abacavir, i-dolutegravir, ne-lamivudine ingeke iyelaphe i-HIV, le mithi inganciphisa amathuba okuba ne-immunodeficiency syndrome (i-AIDS) kanye nezifo ezihlobene ne-HIV ezinjengokutheleleka okukhulu noma umdlavuza. Ukuthatha le mithi kanye nokwenza ucansi oluphephile nokwenza ezinye izinguquko kwimpilo yakho kunganciphisa ubungozi bokuthola noma ukudlulisela igciwane le-HIV kwabanye abantu.

Inhlanganisela ye-abacavir, i-dolutegravir, ne-lamivudine iza njengethebhulethi ezothathwa ngomlomo. Imvamisa kuthathwa kanye ngosuku noma ngaphandle kokudla. Thatha i-abacavir, i-dolutegravir, ne-lamivudine cishe ngesikhathi esifanayo nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-abacavir, i-dolutegravir, ne-lamivudine njengoba nje kuyalelwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

I-Abacavir, i-dolutegravir, ne-lamivudine zisiza ekulawuleni ukutheleleka nge-HIV kodwa zingayelaphi. Qhubeka uthathe i-abacavir, i-dolutegravir, ne-lamivudine noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-abacavir, i-dolutegravir, ne-lamivudine ngaphandle kokukhuluma nodokotela wakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-abacavir, i-dolutegravir, ne-lamivudine,

• Tshela udokotela kanye nosokhemisi wakho uma une-aleji ku-abacavir, i-dolutegravir, ne-lamivudine, noma imuphi omunye umuthi, noma yiziphi izithako ze-abacavir, i-dolutegravir, namaphilisi e-lamivudine. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
• tshela udokotela wakho uma uthatha i-dofetilide (Tikosyn). Udokotela wakho mhlawumbe uzokutshela ukuthi ungathathi i-abacavir, i-dolutegravir, ne-lamivudine uma uthatha lo muthi.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunomsoco, okwenzayo noma ohlela ukukuthatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: carbamazepine (Carbatrol, Equetro, Tegretol, abanye); i-dalfampridine (Ampyra); eminye imishanguzo ye-HIV kubandakanya abacavir (e-Epzicom, eTrizivir, Ziagen), dolutegravir (Tivicay), efavirenz (Sustiva, e-Atripla), emtricitabine (Emtriva, e-Atripla, eComplera, eTruvada, abanye), etravirine (Intelence), i-fosamprenavir (Lexiva) ethathwe nge-ritonavir (Norvir), lamivudine (Epivir, e-Combivir, e-Epzicom, e-Trizivir, abanye), i-nevirapine (Viramune), ne-tipranavir (Aptivus) ethathwe nge-ritonavir (Norvir); i-metformin (iGlumetza, iGlucophage, iRiomet); i-methadone (i-Dolophine, i-Methadose); oxcarbazepine (Oxtellar XR, Trileptal); i-phenobarbital; i-phenytoin (iDilantin, Phenytek); i-rifampin (iRifadin, iRimactane, eRifamate, eRifater); kanye ne-sorbitol noma imithi equkethe i-sorbitol. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• uma uthatha ama-antacids, laxatives, noma ama-multivitamin aqukethe i-aluminium, i-magnesium, noma i-calcium; izithako ze-calcium; izithako zensimbi; i-sucralfate (iCarafate); noma imishanguzo ebhuqiwe efana ne-aspirin e-buffered, thatha i-abacavir, i-dolutegravir, ne-lamivudine okungenani amahora amabili ngaphambi noma amahora ayisithupha ngemuva kokuthatha le mithi.
• utshele udokotela wakho ukuthi uthatha miphi imikhiqizo yamakhambi, ikakhulukazi iSt John's wort. Akufanele uthathe i-wort yaseSt. John ngenkathi uthatha i-abacavir, i-dolutegravir, ne-lamivudine.
• utshele udokotela wakho uma uke waba nesifo sesibindi noma wake waba naso. Udokotela wakho mhlawumbe uzokutshela ukuthi ungathathi i-abacavir, i-dolutegravir, ne-lamivudine.
• utshele udokotela wakho uma ubhema noma uphuza utshwala, noma uma uke waba nomfutho wegazi ophakeme noma unesifo somfutho wegazi ophezulu, isifo sikashukela, isifo sikashukela, noma isifo senhliziyo noma sezinso.
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uzodinga ukwenza ukuhlolwa kokukhulelwa ngaphambi kokuqala ukwelashwa. Akufanele ukhulelwe ngenkathi uthatha i-abacavir, i-dolutegravir, ne-lamivudine. Khuluma nodokotela wakho ngezindlela ezisebenzayo zokulawula ukubeletha ongazisebenzisa ngesikhathi sokwelashwa kwakho. Uma ukhulelwa ngenkathi uthatha i-abacavir, i-dolutegravir, ne-lamivudine, shayela udokotela wakho ngokushesha. IDolutegravir ingalimaza umbungu.
• tshela udokotela wakho uma uncelisa. Akufanele uncelise ibele uma utheleleke nge-HIV noma uma uthatha i-abacavir, i-dolutegravir, ne-lamivudine.
• buza udokotela wakho ngokusetshenziswa okuphephile kweziphuzo ezidakayo nemithi equkethe utshwala ngenkathi uthatha i-abacavir, i-dolutegravir, ne-lamivudine.
• kufanele wazi ukuthi ngenkathi uthatha imishanguzo yokwelapha ukutheleleka nge-HIV, amasosha omzimba wakho angaqina futhi aqale ukulwa nezinye izifo ezazivele zisemzimbeni wakho. Lokhu kungadala ukuthi ube nezimpawu zalezo zifo. Uma unezimpawu ezintsha noma eziya ziba zimbi noma kunini ngesikhathi sokwelashwa kwakho nge-abacavir, i-dolutegravir, ne-lamivudine, qiniseka ukuthi utshela udokotela wakho.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalezi zimpawu ezilandelayo, noma lezo ezishiwo esigabeni ESIBALULEKILE SEXWAYISO, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukukhathala ngokweqile; ubuthakathaka, isiyezi, noma ikhanda elikhanyayo; ukushaya kwenhliziyo okusheshayo noma okungajwayelekile; ubuhlungu bemisipha; ubuhlungu besisu ngokuhlanza nokuhlanza; ukuphefumula noma ukuphefumula kanzima; izimpawu ezinjengomkhuhlane, umkhuhlane, noma ukukhwehlela; noma uzizwe ubanda, ikakhulukazi ezandleni noma emilenzeni
• ukunyakaza kwamathumbu okukhanyayo; ukuphuzi kwesikhumba noma kwamehlo; ukulahlekelwa ukudla; ukopha okungavamile noma ukulimaza; umchamo omnyama ophuzi noma onsundu; noma ubuhlungu engxenyeni engaphezulu kwesokudla yesisu

I-Abacavir, i-dolutegravir, ne-lamivudine ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese). Ungayikhiphi i-desiccant (iphakethe elincane elifakwe nemithi yokubamba umswakama) ebhodleleni lakho.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Gcina i-abacavir, i-dolutegravir, ne-lamivudine esandleni. Ungalindi uze uphelelwe yimithi yokugcwalisa imishanguzo yakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Triumeq^®