Umlobi: Janice Evans
Usuku Lokudalwa: 23 Ujulayi 2021
Ukuvuselela Usuku: 1 Udisemba 2024
Anonim
FDA approves Deflazacort for Duchenne muscular dystrophy
Ividiyo: FDA approves Deflazacort for Duchenne muscular dystrophy

-Delile

I-Deflazacort isetshenziselwa ukwelapha iDuchenne muscular dystrophy (i-DMD; isifo esiqhubekayo lapho imisipha ingasebenzi kahle) kubantu abadala nezingane ezineminyaka emibili nangaphezulu. I-Deflazacort isekilasini lemithi ebizwa nge-corticosteroids. Isebenza ngokunciphisa ukuvuvukala (ukuvuvukala) nangokushintsha indlela amasosha omzimba asebenza ngayo.

I-Deflazacort iza njengethebhulethi nokumiswa (uketshezi) ukuthatha ngomlomo. Imvamisa kuthathwa kanye ngosuku noma ngaphandle kokudla. Thatha i-deflazacort ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-deflazacort njengoba nje kuqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Uma ungeke ukwazi ukuligwinya lonke ithebhulethi, ungahle uyichoboze bese uhlangana ne-appleauce. Ingxube kufanele ithathwe ngokushesha.

Nyakazisa ukumiswa kahle ngaphambi kokusebenzisa ngakunye ukuxuba umuthi ngokulinganayo. Sebenzisa isisetshenziswa sokulinganisa ukukala umthamo we-deflazacort bese ufaka kancane umthamo kuma-ounces amathathu kuya kwayi-4 (90 kuye ku-120 ml) wobisi noma ujusi wezithelo uthathe ngokushesha. Ungahlanganisi ukumiswa kwe-deflazacort nejusi lamagilebhisi.


Udokotela wakho angadinga ukushintsha umthamo wakho we-deflazacort uma uhlangabezana nokucindezeleka okungavamile emzimbeni wakho njengokuhlinzwa, ukugula noma ukutheleleka. Tshela udokotela wakho uma izimpawu zakho ziba ngcono noma ziba zimbi noma uma ugula noma unoshintsho empilweni yakho ngesikhathi sokwelashwa kwakho.

Ungayeki ukuthatha i-deflazacort ngaphandle kokukhuluma nodokotela wakho. Ukuyeka lesi sidakamizwa kungazelele kungadala izimpawu ezifana nokulahlekelwa isifiso sokudla, isisu esibuhlungu, ukuhlanza, ukozela, ukudideka, ikhanda elibuhlungu, umkhuhlane, ubuhlungu bamalunga nemisipha, isikhumba esihlabayo kanye nokwehlisa isisindo. Udokotela wakho mhlawumbe uzokwehlisa umthamo wakho kancane kancane ukuvumela umzimba wakho ukuthi ulungise ngaphambi kokumisa umuthi ngokuphelele. Bheka le miphumela emibi uma unciphisa umthamo wakho kancane kancane nangemva kokuyeka ukuthatha amaphilisi noma ukumiswa ngomlomo. Uma lezi zinkinga zenzeka, shayela udokotela wakho ngokushesha.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.


Ngaphambi kokuthatha i-deflazacort,

  • Tshela udokotela wakho kanye nosokhemisi uma une-aleji ku-deflazacort, noma imiphi eminye imithi, noma iziphi izithako ezikumaphilisi e-deflazacort noma ukumiswa. Buza usokhemisi wakho ukuthola uhlu lwezithako.
  • Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: i-aspirin nezinye izidakamizwa ezingezona ukuvuvukala (ama-NSAID) njenge-ibuprofen (Advil, Motrin) ne-naproxen (Aleve, Naprosyn), carbamazepine (Carbatrol, Epitol, Equetro, Tegretol), clarithromycin (Biaxin , e-Prevpac), efavirenz (Sustiva, e-Atripla), i-fluconazole (i-Diflucan), i-diltiazem (i-Cardizem, i-Cartia, i-Diltzac, i-Taztia), imishanguzo yesifo sikashukela kubandakanya i-insulin, i-phenytoin (i-Dilantin, i-Phenytek), i-rifampin (i-Rifadin, i-Rimactane, i-Rifactane, i-Rifadine, i-Rifadine, i-Rifadin, i-Rifadine , eRifater), imishanguzo yegilo, kanye ne-verapamil (Calan, eTarka, Verelan). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo eminingi ingaxhumana ne-deflazacort, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho nalawo angaveli kulolu hlu.
  • utshele udokotela wakho uma uke waba ne-hepatitis B (HBV, igciwane elithelela isibindi futhi elingadala ukulimala kwesibindi); ukutheleleka kwamehlo i-herpes (uhlobo lokutheleleka kwamehlo oludala ukuqaqamba kwejwabu leso noma iso); inkalakatha (ukufiphalisa ilensi yeso); i-glaucoma (isifo samehlo); umfutho wegazi ophakeme; ukwehluleka kwenhliziyo; ukuhlaselwa yinhliziyo muva nje; isifo sikashukela; izinkinga ezingokomzwelo, ukudangala, noma ezinye izinhlobo zokugula ngengqondo; i-myasthenia gravis (isimo lapho imisipha iba buthaka khona); i-osteoporosis (isimo lapho amathambo eba buthakathaka khona futhi entekenteke futhi engaphuka kalula); i-pheochromocytoma (isimila endlaleni encane eduze kwezinso); izilonda; ihlule legazi emilenzeni, emaphashini, noma emehlweni; noma isibindi, izinso, inhliziyo, amathumbu, i-adrenal, noma isifo se-thyroid. Phinda utshele udokotela wakho uma unanoma yiluphi uhlobo lwe-bacterial, fungal, parasitic, noma ukutheleleka ngegciwane okungalashwa.
  • tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha i-deflazacort, shayela udokotela wakho.
  • uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi uthatha i-deflazacort.
  • thintana nodokotela wakho ukuze ubone uma ngabe udinga ukuthola noma yimiphi imigomo. Kubalulekile ukuthi yonke imishanguzo yokugoma ilungele iminyaka yakho ngaphambi kokuqala ukwelashwa kwakho nge-deflazacort. Ungabi nayo imigomo ngesikhathi sokwelashwa kwakho ngaphandle kokukhuluma nodokotela wakho.
  • kufanele wazi ukuthi i-deflazacort inganciphisa ikhono lakho lokulwa nokutheleleka futhi ingakuvimbela ekuthuthukiseni izimpawu uma uthola ukutheleleka. Hlala kude nabantu abagulayo futhi ugeze izandla zakho kaningi ngenkathi uthatha lo muthi. Qiniseka ukuthi ugwema abantu abane-pox noma isimungumungwane. Shayela udokotela wakho ngokushesha uma ucabanga ukuthi kungenzeka wake wasondela kumuntu owayephethwe umkhuhlane wezinkukhu noma isimungumungwane.

Ungadli isithelo samagilebhisi noma uphuze ijusi lamagilebhisi ngenkathi uthatha lo muthi.


Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Deflazacort ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

  • ikhanda
  • isikhumba esincane, esintekenteke
  • amabala abomvu noma ansomi noma imigqa ngaphansi kwesikhumba
  • ukukhula kwezinwele
  • induna
  • Amehlo aqhamukayo
  • izikhathi zokuya esikhathini ezingajwayelekile noma ezingekho
  • ukuphulukiswa okuphuzile kokusikeka nokulimala
  • izinguquko endleleni okusakazeka ngayo amafutha emzimbeni wonke
  • imisipha ebuthakathaka
  • ubuhlungu obuhlangene
  • ukuchama kaningi emini
  • isiyezi
  • ubunzima bokulala noma ukulala
  • ukwanda kwesifiso sokudla
  • isisu esibuhlungu
  • ukuhlungu obusemhlane
  • isilungulela

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

  • umphimbo obuhlungu, umkhuhlane, amakhaza, ukukhwehlela, noma ezinye izimpawu zokutheleleka
  • isithuthwane
  • ubuhlungu beso, ubomvu, noma ukudwengula
  • izinguquko embonweni
  • ukuvuvukala kwamehlo, ubuso, izindebe, ulimi, umphimbo, izingalo, izandla, izinyawo, amaqakala noma imilenze engezansi
  • ukuphefumula kanzima noma ukugwinya
  • ukuphelelwa umoya
  • ukuzuza kwesisindo ngokungazelelwe
  • ukuqubuka
  • isifuba
  • ukulunywa
  • isikhumba esihlabayo noma esishayayo
  • ubuhlungu besisu
  • ukudideka
  • ushintsho olukhulu ekuguqukeni kwemizwa ebuntwini
  • injabulo engafanele
  • ukudana
  • ubuhlungu obuqhubekayo obuqala endaweni yesisu, kepha bungasabalala baye emuva

I-Deflazacort inganciphisa ukukhula nentuthuko ezinganeni.Udokotela wengane yakho uzobuka ukukhula kwakhe ngokucophelela. Khuluma nodokotela wengane yakho ngezingozi zokunikeza ingane yakho i-deflazacort.

Abantu abasebenzisa i-deflazacort isikhathi eside bangaba ne-glaucoma noma i-cataract. Khuluma nodokotela wakho ngezingozi zokusebenzisa i-deflazacort nokuthi amehlo akho kufanele ahlolwe kangaki ngesikhathi sokwelashwa kwakho.

I-Deflazacort ingakhuphula ubungozi bokuba ne-osteoporosis. Khuluma nodokotela wakho ngezingozi zokusebenzisa lo muthi.

I-Deflazacort ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese). Lahla noma yikuphi ukumiswa okungasetshenziswanga (uketshezi) ngemuva kwenyanga engu-1.

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzohlola umfutho wegazi lakho njalo futhi a-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ku-deflazacort.

Ngaphambi kokwenza noma yiluphi uvivinyo lwelabhoratri, tshela udokotela wakho kanye nabasebenzi belebhuthi ukuthi uthatha i-deflazacort.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

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