Ukujova kweSemaglutide

-Delile

• Ngaphambi kokuthatha umjovo we-semaglutide,
• Umjovo we-Semaglutide ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

Umjovo we-Semaglutide ungakhuphula ubungozi bokuthi uzoba nezicubu zomgudu wegilo, kufaka phakathi i-medullary thyroid carcinoma (MTC; uhlobo lomdlavuza wegilo). Izilwane zaselabhorethri ezinikezwe ama-semaglutide zaba nezimila, kepha akwaziwa ukuthi lo muthi wandisa ingozi yezimila kubantu. Tshela udokotela wakho ukuthi ngabe wena noma omunye emndenini wakho une-MTC noma i-Multiple Endocrine Neoplasia syndrome type 2 (MEN 2; isimo esidala izicubu ezingxenyeni ezingaphezu kweyodwa emzimbeni). Uma kunjalo, udokotela wakho uzokutshela ukuthi ungasebenzisi umjovo we-semaglutide. Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: isigaxa noma ukuvuvukala entanyeni; ukushaqeka; ubunzima bokugwinya; noma ukuphefumula okuncane.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho anga-oda izivivinyo ezithile ukuze ahlole impendulo yomzimba wakho kumjovo we-semaglutide.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa ngomjovo we-semaglutide futhi isikhathi ngasinye lapho ugcwalisa umuthi wakho. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) noma iwebhusayithi yomkhiqizi ukuthola i-Medication Guide.

Khuluma nodokotela wakho ngezingozi zokusebenzisa umjovo we-semaglutide.

Umjovo weSemaglutide usetshenziswa kanye nohlelo lokudla nokuzivocavoca ukulawula amazinga kashukela egazini kubantu abadala abanesifo sikashukela sohlobo 2 (isimo lapho umzimba ungasebenzisi i-insulin ngokujwayelekile ngakho-ke awukwazi ukulawula inani likashukela egazini) lapho eminye imithi ingazange lawula amazinga kashukela ngokwanele. Ibuye isetshenziselwe ukunciphisa ubungozi bokushaywa unhlangothi, isifo senhliziyo, noma ukufa kubantu abadala abane-type 2 yesifo sikashukela kanye nesifo senhliziyo nesifo segazi. Umjovo we-Semaglutide awusetshenziswanga ukwelapha uhlobo lwesifo sikashukela sohlobo 1 (isimo lapho umzimba ungakhiqizi khona i-insulin ngakho-ke awukwazi ukulawula inani likashukela egazini) noma isifo sikashukela ketoacidosis (isimo esibi esingavela uma ushukela ophakeme wegazi ungelashwa) . Umjovo we-Semaglutide awusetshenziswanga esikhundleni se-insulin ukwelapha abantu abanesifo sikashukela abadinga i-insulin. Umjovo we-Semaglutide usesigabeni semithi ebizwa nge-incretin mimetics. Isebenza ngokusiza ama-pancreas ukukhipha inani elifanele le-insulin lapho amazinga kashukela egazi ephezulu. I-insulin isiza ukuhambisa ushukela egazini uye kwezinye izicubu zomzimba lapho usetshenziselwa khona amandla. Umjovo weSemaglutide nawo usebenza ngokunciphisa ukuhamba kokudla esiswini.

Ngokuhamba kwesikhathi, abantu abanesifo sikashukela kanye noshukela ophakeme wegazi bangakhula babe nezinkinga ezinkulu noma ezisongela impilo, kufaka phakathi isifo senhliziyo, isifo sohlangothi, izinkinga zezinso, ukulimala kwemizwa nezinkinga zamehlo. Ukusebenzisa imithi, ukwenza izinguquko endleleni ophila ngayo (isb., Ukudla, ukuzivocavoca, ukuyeka ukubhema), nokuhlola njalo ushukela wegazi lakho kungasiza ukuphatha isifo sikashukela futhi kuthuthukise impilo yakho. Lokhu kwelashwa kunganciphisa namathuba akho okuhlaselwa yisifo senhliziyo, isifo sohlangothi, noma ezinye izinkinga ezihlobene nesifo sikashukela njengokuhluleka kwezinso, ukulimala kwemizwa (okundikindiki, imilenze ebandayo noma izinyawo; ukwehla kwekhono lezocansi kwabesilisa nabesifazane), izinkinga zamehlo, kufaka phakathi izinguquko noma ukulahleka kombono, noma isifo sezinsini. Udokotela wakho nabanye abahlinzeki bezokunakekelwa kwezempilo bazokhuluma nawe ngendlela engcono yokuphatha isifo sikashukela.

Umjovo we-Semaglutide uza njengesisombululo (uketshezi) epeni lokufaka elinqunyelwe ukufaka umjovo ngaphansi (kwesikhumba). Imvamisa ijovwa kanye ngesonto ngaphandle kokubheka ukudla. Sebenzisa umjovo we-semaglutide ngosuku olufanayo evikini ngalinye nganoma yisiphi isikhathi sosuku. Ungaguqula usuku lwesonto olisebenzisa i-semaglutide inqobo nje uma sekuyizinsuku ezi-2 noma ngaphezulu (amahora angama-48 noma ngaphezulu) selokhu wasebenzisa umthamo wakho wokugcina. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Sebenzisa umjovo we-semaglutide njengoba uqondisiwe. Ungayisebenzisi ngaphezulu noma ngaphansi kwayo noma uyisebenzise kaningi kunokuyalelwa ngudokotela wakho.

Udokotela wakho kungenzeka akuqale ngomthamo ophansi womjovo we-semaglutide futhi akhuphule umthamo wakho ngemuva kwamasonto e-4. Udokotela wakho angaphinde akhuphule umthamo wakho ngemuva kwamanye amasonto ama-4 ngokuya ngempendulo yomzimba wakho emithini.

Umjovo weSemaglutide ulawula isifo sikashukela kepha awuselaphi. Qhubeka nokusebenzisa umjovo we-semaglutide noma ngabe uzizwa uphilile. Ungayeki ukusebenzisa umjovo we-semaglutide ngaphandle kokukhuluma nodokotela wakho.

Funda ngokucophelela imiyalelo yomkhiqizi yokusetshenziswa eza nomuthi. Le miyalo ichaza ukuthi ungawujova kanjani umthamo womjovo we-semaglutide. Qiniseka ukuthi ubuza usokhemisi noma udokotela wakho uma unemibuzo mayelana nokuthi ungawujova kanjani lo muthi.

Njalo bheka isisombululo se-semaglutide ngaphambi kokusijova. Kufanele icace, ingenambala, futhi ingabi nezinhlayiya. Ungayisebenzisi i-semaglutide uma inombala, inamafu, ijiyile, noma iqukethe izinhlayiya eziqinile, noma uma usuku lokuphelelwa yisikhathi ebhodleleni seludlulile.

Ungalokothi usebenzise izinaliti futhi ungalokothi wabelane ngezinaliti noma izibaya. Susa njalo inaliti ngemuva nje kokujova umthamo wakho. Lahla izinaliti esitsheni esingamelana nokubhoboza. Buza udokotela wakho noma usokhemisi ukuthi ungasilahla kanjani isitsha esimelana nokubhoboza.

Ungafaka i-semaglutide engalweni yakho ephezulu, ethangeni, noma esiswini. Shintsha (jikelezisa) indawo yokujova ngomjovo ngamunye. Ungafaka i-semaglutide ne-insulin endaweni efanayo yomzimba, kepha akufanele unikeze imijovo eduze komunye nomunye. Vumela ipeni ukuthi lifudumale ekamelweni lokushisa ngaphambi kokujova uma ipeni ligcinwe esiqandisini.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha umjovo we-semaglutide,

• Tshela udokotela wakho kanye nosokhemisi uma une-allergies ku-semaglutide, albiglutide (Tanzeum; ayisatholakali e-US), dulaglutide (Trulicity), exenatide (Bydureon, Byetta), liraglutide (Saxenda, Victoza), lixisenatide (Adlyxin, eSoliqua) , noma imuphi omunye umuthi, noma iziphi izithako zomjovo we-semaglutide. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Kubaluleke kakhulu ukutshela udokotela wakho ngayo yonke imithi oyiphuzayo ngomlomo ngoba i-semaglutide ingashintsha indlela umzimba wakho oyithatha ngayo le mithi. Futhi qiniseka ukuthi usho i-insulin kanye ne-sulfonylureas efana ne-chlorpropamide (i-Diabinese, i-Glucamide), i-glimepiride (i-Amaryl, ku-Duetact), i-glipizide (i-Glucotrol), i-glyburide (i-DiaBeta, i-Glynase), i-tolazamide, ne-tolbutamide. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• Tshela udokotela wakho uma uke waba ne-pancreatitis (ukuvuvukala kwamanyikwe), isifo sikashukela sokuphindaphinda (ukulimala kwamehlo okubangelwa yisifo sikashukela), noma isifo sezinso. Phinda utshele udokotela wakho uma usanda kuba nohudo, isicanucanu, noma ukuhlanza noma uma ungakwazi ukuphuza uketshezi ngomlomo, okungadala ukoma (ukulahlekelwa inani elikhulu lamanzi omzimba).
• tshela udokotela wakho uma uhlela ukukhulelwa. Udokotela wakho angakutshela ukuthi uyeke ukusebenzisa umjovo we-semaglutide izinyanga ezi-2 ngaphambi kokukhulelwa okuhleliwe.
• utshele udokotela wakho uma ukhulelwe noma uncelisa. Uma ukhulelwa ngenkathi usebenzisa umjovo we-semaglutide, shayela udokotela wakho.
• buza udokotela wakho ukuthi wenzeni uma kunoshintsho olukhulu ekudleni kwakho, ekuzivocavoca umzimba, noma esisindweni; noma uma ugula, uba nesifo noma umkhuhlane, ube nengcindezi engajwayelekile, noma ulimale. Lezi zinguquko nezimo zingathinta ushukela wakho wegazi kanye nenani lomjovo we-semaglutide ongawudinga.

Qiniseka ukuthi ulandela zonke izincomo zokuzivocavoca nezokudla ezenziwa ngudokotela wakho noma udokotela odlayo.

Jova umthamo ophuthelwe ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma kudlule izinsuku ezingaphezu kwezingu-5 kusukela kumthamo ongabanjwanga, weqa umthamo ophuthelwe bese uqhubeka nesimiso sakho sokulinganisa. Musa ukujova umthamo ophindwe kabili ukwenzela okulahlekile.

Umjovo we-Semaglutide ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isicanucanu
• ukuhlanza
• isifo sohudo
• ubuhlungu besisu
• ukuqunjelwa
• isilungulela
• ukubhoboza

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ubuhlungu obuqhubekayo obuqala ngaphezulu kwesobunxele noma maphakathi nesisu kepha bungasabalala buye emhlane, ngokuhlanza noma ngaphandle kokuhlanza
• ukuqubuka; ukulunywa; ukuvuvukala kwamehlo, ubuso, umlomo, ulimi, noma umphimbo; noma ukuphefumula kanzima noma ukugwinya
• ukuncipha kokuchama; noma ukuvuvukala kwemilenze, amaqakala, noma izinyawo
• umbono uyashintsha

Umjovo we-Semaglutide ungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi usebenzisa lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ingena futhi ingafinyeleleki ezinganeni. Yigcine kude nokukhanya nokushisa, ufake ipeni. Gcina izibaya ze-semaglutide ezingasetshenzisiwe esiqandisini (36 ° F kuye ku-46 ° F [2 ° C kuye ku-8 ° C]) kodwa ungazibeki eduze kwento epholisa isiqandisi. Uma ipeni le-semaglutide selisetshenzisiwe ungaligcina ekamelweni lokushisa (59 ° F kuye ku-86 ° F [15 ° C kuye ku-30 ​​° C]) noma esiqandisini. Ungafrizi. Ungasebenzisi i-semaglutide uma iqandisiwe.

Lapho izibaya ezihambayo ezisetshenziswayo zingagcinwa ekamelweni lokushisa (59 ° F kuye ku-86 ° F [15 ° C kuye ku-30 ​​° C]) (hhayi egumbini legilavu ​​lemoto noma kwenye indawo eshisayo).

Bhala usuku owaqala ngalo ukusebenzisa ipeni le-semaglutide, bese ulilahla ngemuva kwezinsuku ezingama-56, noma ngabe kukhona isixazululo esisele esibayeni.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

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