IPenicillamine

-Delile

• Ngaphambi kokuthatha i-penicillamine,
• IPenicillamine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu shayela udokotela wakho ngokushesha:

IPenicillamine isetshenziselwa ukwelapha isifo sikaWilson (isimo esizuzwe njengefa esidala ukuthi ithusi lakheke emzimbeni futhi kungahle kube nezimpawu ezinqala) kanye necystinuria (isimo esizuzwe njengefa esingaholela ezinsweni zezinso). Iphinde isetshenziswe ngokuhlangana nezinye izindlela zokwelapha i-rheumatoid arthritis (isimo lapho amasosha omzimba ehlasela khona amalunga awo, abangele ubuhlungu, ukuvuvukala, nokulahleka komsebenzi) okungazange kube ngcono ngemuva kokwelashwa ngeminye imithi. IPenicillamine isekilasini lemithi ebizwa ngabaphikisi bensimbi enzima. Kuyasebenza ukwelapha isifo sikaWilson ngokubophela ithusi elengeziwe emzimbeni nokusibangela ukuthi sishiye umzimba ngomchamo. Isebenza ukwelapha i-cystinuria ngokubophezela entweni eyenza amatshe ezinso nokuyivimba ukuthi yakhe futhi yakhe amatshe. Kusebenza ekwelapheni isifo samathambo ngokunciphisa ezinye izenzo zesistimu yomzimba.

I-Penicillamine iza njenge-capsule nanjenge-tablet ezothathwa ngomlomo. Imvamisa iphuzwa esiswini esingenalutho okungenani ihora eli-1 ngaphambi noma amahora amabili ngemuva kokudla, futhi okungenani ihora eli-1 ngaphambi noma ngemuva kwanoma yikuphi ukudla noma ubisi. Ekwelapheni isifo sikaWilson ne-cystinuria, i-penicillamine ivame ukuthathwa kane ngosuku. Ekwelapheni i-rheumatoid arthritis kuvame ukuthatha kanye ngosuku, kepha ngemithamo ekhuphukile, ingaphuzwa izikhathi ezine ngosuku. Udokotela wakho uzoncoma ukuthi kufanele uthole ukwelashwa isikhathi esingakanani ngokuya ngesimo sakho, ukuthi umzimba wakho uphendula kahle kanjani emithini, kanye nanoma imiphi imiphumela emibi ohlangabezana nayo. Thatha i-penicillamine cishe ngesikhathi esifanayo (ama) nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-penicillamine njengoba nje uqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Udokotela wakho mhlawumbe uzokuqala ngomthamo ophansi we-penicillamine futhi akhuphule kancane umthamo wakho.

Ukwelashwa kwesifo sikaWilson nesifo samathambo kungathatha inyanga eyodwa kuya kwezintathu noma ngaphezulu ngaphambi kokuba uzwe inzuzo ephelele ye-penicillamine. Kukho konke ukusetshenziswa qhubeka nokuthatha i-penicillamine noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-penicillamine ngaphandle kokukhuluma nodokotela wakho, noma ngabe izimpawu zakho ziba zimbi kakhulu. Uma uyeka ukuthatha i-penicillamine usengozini enkulu yokuthola ukusabela okweqile lapho uqala ukuthatha umuthi futhi.

Qiniseka ukuthi utshela udokotela wakho ukuthi uzizwa kanjani ngesikhathi sokwelashwa kwakho nge-penicillamine. Udokotela wakho angakuphatha ngeminye imithi, noma abambezele ukwelashwa kwakho, anciphise umthamo wakho, noma ayeke ukwelashwa kwakho ngokuya ngemiphumela oyitholayo.

IPenicillamine kwesinye isikhathi isetshenziswa njengemithi yokulandelela ubuthi bomthofu ngemuva kokuphathwa ngeminye imithi. Futhi kwesinye isikhathi kusetshenziselwa ukwelapha izinhlobo ezithile zezifo zesibindi. Khuluma nodokotela wakho ngezingozi zokusebenzisa lo muthi ngesimo sakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-penicillamine,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-penicillamine, penicillin, noma imuphi omunye umuthi, noma iziphi izithako ezikuma-penicillamine capsules noma amaphilisi. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qinisekisa ukusho noma yikuphi kokulandelayo: izinhlanganisela zegolide ezifana ne-auranofin (i-Ridaura) ne-aurothioglucose (i-Solganol); imithi elwa nomalaleveva efana ne-chloroquine, i-hydroxychloroquine (i-Plaquenil); kanye nama-immunosuppressants athile afana ne-azathioprine (Azasan, Imuran), ne-methotrexate (Otrexup, Rasuvo, Trexall, Xatmep). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo eminingi ingaxhumana ne-penicillamine, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu.
• uma uthatha insimbi equkethe umkhiqizo, thatha amahora amabili ngaphambi noma ngemuva uma uthatha i-penicillamine. Uma uthatha noma imuphi omunye umuthi, i-antacid, noma i-zinc equkethe umkhiqizo, thatha ihora eli-1 ngaphambi noma ngemuva kokuthatha i-penicillamine.
• Tshela udokotela wakho uma wake welashwa nge-penicillamine esikhathini esedlule futhi waba nomphumela omubi ohlobene negazi. Udokotela wakho uzokutshela ukuthi ungathathi i-penicillamine futhi.
• Tshela udokotela wakho uma ngabe uke waphendula ngokungathi sína kumakhemikhali egolide, noma uma uke waba nesifo sezinso noma wake waba naso.
• tshela udokotela wakho uma ukhulelwe, noma uma uhlela ukukhulelwa. Uma ukhulelwa ngenkathi uthatha i-penicillamine, shayela udokotela wakho ngokushesha.
• tshela udokotela wakho uma uncelisa. Akufanele uncelise ibele ngenkathi uthola ukwelashwa nge-penicillamine.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi uthatha i-penicillamine.
• udokotela wakho mhlawumbe uzokutshela ukuthi uthathe i-pyridoxine (uvithamini B₆) engeza ngesikhathi sokwelashwa kwakho nge-penicillamine.

Uma welashelwa isifo sikaWilson udokotela wakho mhlawumbe uzokuncoma ukudla okukhethekile okungakutholi kakhulu ithusi. Lokhu kudla kugwema okusanhlamvu nezengezo zokudla ezinothiswa ngethusi, ushokoledi, amantongomane, izimbaza, amakhowe, isibindi, ama-molasses, i-broccoli, nokunye ukudla okuphezulu okuqukethe ukudla. Udokotela wakho futhi angancoma ukuthi uphuze amanzi acolisisiwe noma adonswe ngamanzi, esikhundleni samanzi ompompi avamile. Qiniseka ukuthi ulandela zonke izincomo zokudla ezenziwe udokotela wakho.

Uma welashelwa i-cystinuria udokotela wakho angakutusa ukudla okukhethekile okungaphansi kwe-methionine (uhlobo lwamaprotheni). Kodwa-ke uma uyingane noma uma ukhulelwe udokotela wakho kungenzeka angakutusi lokhu kudla. Udokotela wakho futhi mhlawumbe uzoncoma ukuthi uphuze uketshezi olwanele.

Uma welashelwa i-rheumatoid arthritis, qhubeka nokudla kwakho okujwayelekile ngaphandle kokuthi udokotela wakho akutshele ngenye indlela.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

IPenicillamine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ukulahlekelwa isifiso sokudla
• shintsha ngendlela izinto ezinambitha ngayo
• isicanucanu
• ukuhlanza
• isifo sohudo
• ubuhlungu besisu
• imibimbi yesikhumba
• izipikili ziyashintsha

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu shayela udokotela wakho ngokushesha:

• ukuqubuka, ukulunywa, isifuba, ukuchitheka kwesikhumba, umkhuhlane, ubuhlungu bamalunga, noma ama-lymph node avuvukile
• amabhamuza abuhlungu noma alumayo nezilonda esikhunjeni, emlonyeni nasezitho zangasese
• umkhuhlane, umphimbo obuhlungu, amakhaza, ukopha okungavamile noma ukulimaza
• ukuphefumula, ukukhwehlela okungaqondakali noma ukuphefumula
• umchamo onamagwebu noma obomvana, obomvu, onsundu noma onegazi
• ubuthakathaka bemisipha, amajwabu amehlo alengayo, noma ukubona kabili

IPenicillamine ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ku-penicillamine.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

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