I-Lofexidine

-Delile

• Ngaphambi kokuthatha i-lofexidine,
• I-Lofexidine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu noma lezo ezisohlwini lwe-SPECIAL PRECAUTIONS section, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

I-Lofexidine isetshenziselwa ukuphatha izimpawu zokuhoxa kwe-opioid (isb., Ukuzwa ukugula, amajaqamba esiswini, ukuqubuka kwemisipha noma ukudikiza, ukuzwa okubandayo, ukushaya kwenhliziyo, ukuqina kwemisipha, ubuhlungu nezinhlungu, ukuzamula, amehlo agijimayo, noma ubunzima bokulala noma ukulala) okungase kwenzeka ngemuva kokuthi umuthi we-opioid umiswe ngokuzumayo. ILofexidine isekilasini lemithi ebizwa ngokuthi i-central alpha adrenergic agonists. Isebenza ngokuphumuza imithambo yegazi ukuze igazi ligeleze kalula emzimbeni.

ILofexidine iza njengethebhulethi ezothathwa ngomlomo. Imvamisa kuthathwa noma ngaphandle kokudla kane ngosuku (amahora ama-5 kuye kwayisithupha phakathi kwesilinganiso ngasinye) ukuphatha izimpawu zokuhoxa ngemuva kokusebenzisa kwakho okokugcina umuthi we-opioid. Kungathathwa kuze kube yizinsuku eziyi-14 ngokuya ngezimpawu zakho nemiphumela engemihle. Thatha i-lofexidine cishe ngezikhathi ezifanayo nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-lofexidine njengoba nje iqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Udokotela wakho angadinga ukunciphisa, ukuphazamisa, noma ukuyeka ukwelashwa kwakho uma uhlangabezana nemiphumela ethile emibi. Khuluma nodokotela wakho mayelana nokuthi uzizwa kanjani ngesikhathi sokwelashwa kwakho.

ILofexidine isiza ukunciphisa ubunzima bezimpawu zokuhoxa ze-opioid kepha kungenzeka ingazivimbeli ngokuphelele. Ungayeki ukuthatha i-lofexidine ngaphandle kokukhuluma nodokotela wakho. Uma uyeka ngokungazelelwe ukuthatha i-lofexidine, umfutho wegazi ungakhuphuka noma ungathola izimpawu zokuhoxa njengokuhuda, ubunzima bokulala noma ukulala, ukukhathazeka, ukubanda, ukujuluka, nobuhlungu bomlenze noma bengalo. Udokotela wakho uzokutshela ukuthi wehlise umthamo wakho kancane kancane ezinsukwini ezimbili kuya kwezingu-4.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-lofexidine,

• Tshela udokotela kanye nosokhemisi wakho uma une-aleji ye-lofexidine, noma imiphi eminye imithi, noma iziphi izithako ezisemaphilisi e-lofexidine. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha.Qiniseka ukuthi usho noma ikuphi kokulandelayo: amitriptyline; imishanguzo; ama-antifungals anjenge ketoconazole, itraconazole (Onmel, Sporanox), noma i-voriconazole (Vfend); imithi yokukhathazeka; ama-barbiturates afana ne-phenobarbital (Luminal); ama-benzodiazepines afana ne-alprazolam (Xanax), i-lorazepam (Ativan), ne-triazolam (i-Halcion); i-clarithromycin (i-Biaxin, ku-Prevpac); i-erythromycin (E.E.S., E-Mycin, Erythrocin); i-granisetron (i-Kytril); i-haloperidol (iHaldol); imithi yomfutho wegazi ophakeme; imishanguzo ethile yegciwane lesandulela ngculazi (i-HIV) noma i-immunodeficiency syndrome (i-AIDS) efana ne-atazanavir (Reyataz), i-nelfinavir (i-Viracept), i-ritonavir (i-Norvir, e-Kaletra), ne-saquinavir (i-Invirase); imithi ethile yokushaya kwenhliziyo okungajwayelekile njenge-amiodarone (Pacerone), i-disopyramide (i-Norpace), i-dofetilide (iTikosyn), i-procainamide, i-quinidine, ne-sotalol (i-Betapace, i-Betapace AF, i-Sotylize); imithi yokugula kwengqondo; i-methadone (i-Dolophine, i-Methadose); i-naltrexone (i-Vivitrol) lapho inikezwa ngomlomo; i-ondansetron (iZofran); imithi yezinhlungu; i-paroxetine (Brisdelle, Paxil, Pexeva); isidambisi; amaphilisi okulala; kanye nezithambisi. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• Tshela udokotela wakho uma wena noma omunye emndenini wakho enesifo se-QT eside (isimo esandisa ingozi yokuhlaselwa ukushaya kwenhliziyo okungajwayelekile okungadala ukuquleka noma ukufa ngokuzuma), noma olunye uhlobo lokushaya kwenhliziyo okungajwayelekile noma inkinga yesigqi senhliziyo, noma uma uke waba namazinga aphansi egazi we-magnesium noma i-potassium egazini lakho, isifo senhliziyo, ukwehluleka kwenhliziyo, umfutho wegazi ophansi noma ophakeme, isifo se-cerebrovascular (ukuvimba noma ukwenza buthaka imithambo yegazi ebuchosheni noma eholele ebuchosheni) , noma inhliziyo, isibindi noma isifo sezinso.
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha i-lofexidine, shayela udokotela wakho.
• kufanele wazi ukuthi i-lofexidine ingakwenza ukozele. Ungashayeli imoto noma usebenzise imishini uze wazi ukuthi lo muthi ukuthinta kanjani.
• buza udokotela wakho ngokusetshenziswa okuphephile kweziphuzo ezidakayo ngenkathi uthatha i-lofexidine. Utshwala bungenza imiphumela emibi evela ku-lofexidine ibe yimbi kakhulu.
• kufanele wazi ukuthi i-lofexidine ingadala isizungu, ikhanda elikhanyayo, nokuquleka lapho uvuka ngokushesha okukhulu kusuka endaweni yokulala. Ukugwema le nkinga, phuma embhedeni kancane, uphumule izinyawo zakho phansi imizuzu embalwa ngaphambi kokuma. Uma uhlangabezana nalezi zimpawu, hlala noma ulale phansi. Uma lezi zimpawu zingathuthuki, shayela udokotela wakho.
• kufanele wazi ukuthi ungaquleka uma uphelelwa amanzi emzimbeni noma ushisa ngokweqile ngenkathi welashwa nge-lofexidine. Qiniseka ukuthi uphuza iziphuzo eziningi futhi uhlale upholile ngenkathi uthatha lo muthi.
• kufanele wazi ukuthi ngemuva kwesikhathi sokungazisebenzisi izidakamizwa ze-opioid, ungahle uzwele kakhulu emiphumeleni yama-opioid futhi usengozini enkulu yokweqisa ngokweqile uma ubungathatha noma usebenzise kakhulu.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Bese uqala ukuthatha umthamo wakho olandelayo (amahora ama-5 kuya kwayisithupha kamuva). Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Lofexidine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ubunzima bokulala noma ukulala
• umlomo owomile
• kukhala ezindlebeni

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu noma lezo ezisohlwini lwe-SPECIAL PRECAUTIONS section, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukuquleka
• isiyezi noma ikhanda elikhanyayo

I-Lofexidine ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese). Ungayisusi i-desiccant (i-agent eyomisa) ebhodleleni.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• ukuquleka
• ukuthambisa

Gcina wonke ama-aphoyintimenti nodokotela wakho. Udokotela wakho anga-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ku-lofexidine.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Lucemyra^®