Elagolix

-Delile

• Ngaphambi kokuthatha i-elagolix,
• I-Elagolix ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

I-Elagolix isetshenziselwa ukuphatha izinhlungu ngenxa ye-endometriosis (isimo lapho uhlobo lwethishu eligudla isibeletho [isibeletho] lukhula kwezinye izindawo zomzimba futhi lubangele ukungabi nenzalo, ubuhlungu ngaphambi nangesikhathi sokuya esikhathini, ubuhlungu ngesikhathi nangemva kokuya ocansini, nokopha okunzima noma okungajwayelekile). U-Elagolix usesigabeni semithi ebizwa nge-gonadotropin-releasing hormone (GnRH) receptor antagonists. Isebenza ngokunciphisa inani lamahomoni athile emzimbeni.

I-Elagolix iza njengethebhulethi ezothathwa ngomlomo. Imvamisa kuthathwa noma ngaphandle kokudla kanye ngosuku kuze kube yizinyanga ezingama-24 noma kabili ngosuku kuze kube izinyanga eziyisithupha. Thatha i-elagolix cishe ngesikhathi esifanayo (ama) nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-elagolix njengoba nje kuqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Udokotela wakho angakunikeza noma ancoma ukwengezwa kwe-calcium nevithamini D okufanele ukwenze ngesikhathi sokwelashwa kwakho. Kufanele uthathe lezi zithasiselo njengoba uqondiswe ngudokotela wakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-elagolix,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-elagolix, noma imiphi eminye imithi, noma iziphi izithako kumaphilisi e-elagolix. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
• Tshela udokotela wakho uma uthatha i-cyclosporine (Gengraf, Neoral, Sandimmune) noma i-gemfibrozil (Lopid). Udokotela wakho mhlawumbe uzokutshela ukuthi ungathathi i-elagolix uma uthatha omunye wale mithi.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: i-digoxin (i-Lanoxin), i-ketoconazole (i-Nizoral), i-midazolam, i-rifampin (i-Rifadin, i-Rimactane, i-Rifamate, i-Rifater), ne-rosuvastatin (i-Crestor). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imithi eminingi ingahle ihlanganyele ne-elagolix, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho nalawo angaveli kulolu hlu.
• Tshela udokotela wakho uma une-osteoporosis (isimo lapho amathambo eba mncane futhi abe buthakathaka futhi aphuke kalula), noma uma uke waba nesifo sesibindi noma wake waba naso. Udokotela wakho angakutshela ukuthi ungathathi i-elagolix.
• utshele udokotela wakho uma uke waphuka amathambo, wakhathazeka, wakhathazeka, wenza izinguquko ezingavamile ekuziphatheni noma emoyeni, noma wacabanga noma wazama ukuzibulala.
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Ungathathi i-elagolix uma ukhulelwe noma ucabanga ukuthi ukhulelwe. Udokotela wakho uzokwenza isivivinyo sokukhulelwa ngaphambi kokuqala ukwelashwa noma akutshele ukuthi uqale ukwelashwa kwakho ezinsukwini eziyi-7 ngemuva kokuqala ukuya esikhathini ukuze uqiniseke ukuthi awukhulelwe lapho uthatha i-elagolix. I-Elagolix ingaphazamisa ukusebenza kwezindlela ezithile zokuvimbela inzalo zamahomoni, ngakho-ke akufanele uzisebenzise njengendlela yakho kuphela yokulawula ukubeletha ngesikhathi sokwelashwa kwakho. Uzodinga ukusebenzisa indlela ethembekile engeyona eye-hormonal control control ukuvimbela ukukhulelwa ngesikhathi sokwelashwa kwakho nangesonto eli-1 ngemuva komthamo wakho wokugcina. Buza udokotela wakho ukuthi akusize ukhethe indlela yokulawula ukubeletha ezokusebenzela. Uma ukhulelwa ngenkathi uthatha i-elagolix, shayela udokotela wakho ngokushesha. I-Elagolix ingalimaza umbungu.
• kufanele wazi ukuthi impilo yakho yengqondo ingashintsha ngezindlela ezingalindelekile futhi ungazibulala (ucabanga ngokuzilimaza noma ukuzibulala noma ukuhlela noma ukuzama ukwenza kanjalo) ngenkathi uthatha i-elagolix. Wena, umndeni wakho, noma umnakekeli wakho kufanele ushayele udokotela wakho ngokushesha uma uhlangabezana nalezi zimpawu ezilandelayo: ukucasuka okusha noma okuba kubi kakhulu, ukukhathazeka, noma ukucindezeleka; ukukhuluma noma ukucabanga ngokufuna ukuzilimaza noma ukuqeda impilo yakho; ukuhoxa kubangani nomndeni; ukukhathazeka ngokufa nokufa; noma olunye uguquko olungajwayelekile ekuziphatheni noma emoyeni. Qiniseka ukuthi umndeni wakho noma umnakekeli wakho uyazi ukuthi yiziphi izimpawu ezingaba zimbi kakhulu ukuze bakwazi ukubiza udokotela uma ungakwazi ukuzifunela ukwelashwa wedwa.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Thatha umthamo ongabanjwanga ngosuku olufanayo ngokushesha uma uwukhumbula. Qhubeka nesimiso sakho sokulinganisa okuvamile. Ungathathi umthamo ongaphezu kowodwa usuku ngalunye (uma uwuthatha kanye ngosuku) noma ngaphezulu kwemithamo emibili ngosuku (uma uyithatha kabili ngosuku). Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Elagolix ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ukushisa okushisayo (ukuqhuma okungazelelwe kokushisa komzimba okuncane noma okukhulu)
• ukujuluka ebusuku
• ikhanda
• isicanucanu
• isifo sohudo
• ukuqunjelwa
• ubuhlungu besisu
• ukuzuza kwesisindo
• ubunzima bokulala noma ukulala
• izinguquko esikhathini sokuya esikhathini (ukuphuma kwegazi ngokungajwayelekile noma ukubona, ukuphuma kancane noma ukungabikho nhlobo, ukunciphisa ubude bezikhathi)
• ubuhlungu obuhlangene
• izinguquko ezifisweni zocansi

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• okuphuzi kwesikhumba noma kwamehlo; umchamo onombala omnyama; ukukhathala ngokweqile; isicanucanu nokuhlanza; ubuhlungu besisu sangaphezulu kwesokudla; ukopha okungavamile noma ukulinyazwa

I-Elagolix ingadala noma yenze mandundu i-osteoporosis. Kunganciphisa ukuminyana kwamathambo akho futhi kwandise amathuba okuphuka kwamathambo nokuqhekeka. Khuluma nodokotela wakho ngezingozi zokuthatha lo muthi.

I-Elagolix ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina amaphilisi ekamelweni lokushisa noma esiqandisini (2-30 ° C) futhi kude nokushisa okwedlulele nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho angalawula izivivinyo ezithile zebhu ngaphambi nangesikhathi sokwelashwa kwakho ukuze ahlole impendulo yomzimba wakho ku-elagolix.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• U-Orilissa^®