Umlobi: Clyde Lopez
Usuku Lokudalwa: 26 Ujulayi 2021
Ukuvuselela Usuku: 18 Unovemba 2024
Anonim
New Prescribing Information on Survival Benefit for Nubeqa® (Darolutamide) Approved
Ividiyo: New Prescribing Information on Survival Benefit for Nubeqa® (Darolutamide) Approved

-Delile

I-Darolutamide isetshenziselwa ukwelapha izinhlobo ezithile zomdlavuza wendlala yesinye (umdlavuza oqala endlaleni yobulili [indlala yokuzala yowesilisa]) ongazange usabalalele kwezinye izingxenye zomzimba emadodeni angakasizwanga ngezinye izindlela zokwelapha. UDarolutamide usesigabeni semithi ebizwa nge-androgen receptor inhibitors. Isebenza ngokuvimba imiphumela ye-androgen (i-hormone yokuzala yowesilisa) ukunqanda ukukhula nokusabalala kwamangqamuzana omdlavuza.

UDarolutamide uza njengethebhulethi azoyithatha ngomlomo. Imvamisa kuthathwa ngokudla kabili ngosuku. Thatha i-darolutamide cishe ngesikhathi esifanayo (ama) nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-darolutamide njengoba nje kuqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Gwinya wonke amaphilisi; ungawahlukanisi, ungawahlafune noma uwagxoze.

Udokotela wakho angakutshela ukuthi uyeke ukuthatha i-darolutamide isikhashana noma wehlise umthamo wakho uma uba nemiphumela emibi ngesikhathi sokwelashwa kwakho. Qiniseka ukuthi ukhuluma nodokotela wakho mayelana nokuthi uzizwa kanjani ngesikhathi sokwelashwa kwakho nge-darolutamide.


Uma udokotela wakho enikeze omunye umuthi onjenge-goserelin (Zoladex), i-histrelin (i-Supprelin LA, i-Vantas), i-leuprolide (i-Eligard, i-Lupron), noma i-triptorelin (i-Trelstar) yokwelapha umdlavuza wakho wendlala yesinye, uzodinga ukuqhubeka nokuthola lo muthi ngesikhathi sakho ukwelashwa nge-darolutamide.

Qhubeka uthathe i-darolutamide noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-darolutamide ngaphandle kokukhuluma nodokotela wakho.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-darolutamide,

  • Tshela udokotela kanye nosokhemisi wakho uma unegciwane ku-darolutamide, noma imiphi eminye imithi, noma iziphi izithako ezikumaphilisi e-darolutamide. Buza usokhemisi wakho ukuthola uhlu lwezithako.
  • Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: ama-antifungal athile afana ne-itraconazole (Sporanox) ne-ketoconazole (Nizoral), i-apalutamide, i-carbamazepine (i-Carbatrol, i-Equetro, i-Tegretol), i-clarithromycin (i-Biaxin); i-fosphenytoin (i-Cerebyx), i-phenytoin (i-Dilantin, i-Phenytek), i-rifampin (i-Rimactane, e-Rifamate, e-Rifater), ne-ritonavir (i-Norvir, e-Kaletra, e-Technivie). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo eminingi ingaxhumana ne-darolutamide, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu.
  • utshele udokotela wakho ukuthi yimiphi imikhiqizo yamakhambi oyithathayo, ikakhulukazi iSt John's Wort.
  • tshela udokotela wakho uma uke waba nesifo sezinso noma sesibindi.
  • kufanele wazi ukuthi i-darolutamide isetshenziselwa abesilisa kuphela. Abesifazane akufanele bathathe le mithi, ikakhulukazi uma bekhulelwe noma bengakhulelwa noma bencelisa. Uma ithathwa ngabesifazane abakhulelwe, i-darolutamide ingalimaza umbungu. Uma owesifazane okhulelwe ethatha i-darolutamide, kufanele abize udokotela wakhe ngokushesha. Uma umlingani wakho wesifazane engakhulelwe kepha engakhulelwa, wena nomlingani wakho kufanele nisebenzise ukulawulwa kokubeletha ngesikhathi sokwelashwa kwenu nangesonto eli-1 ngemuva komthamo wakho wokugcina.
  • kufanele wazi ukuthi lo muthi unganciphisa ukuzala emadodeni. Kodwa-ke, akufanele ucabange ukuthi umlingani wakho wesifazane akakwazi ukukhulelwa ngesikhathi sokwelashwa kwakho.

Ungadli isithelo samagilebhisi noma uphuze ijusi lamagilebhisi ngenkathi uthatha lo muthi.


Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

IDarolutamide ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

  • ukukhathala ngokweqile
  • ubuhlungu bengalo, umlenze, isandla, noma unyawo

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

  • ubuhlungu bengalo, umlenze, isandla, noma unyawo
  • ukuqubuka
  • igazi emchameni
  • engakwazi ukuchama
  • umkhuhlane, ukuphefumula okusheshayo kanye / noma okungajulile, noma ukukhwehlela

I-Darolutamide ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).


Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho angalawula izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ku-darolutamide.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

  • UNubeqa®
Kugcine ukubuyekezwa - 09/15/2019

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