Inaliti ye-Phenytoin

-Delile

• Ngaphambi kokuthola umjovo we-phenytoin,
• I-Phenytoin ingadala ukwanda kushukela wegazi lakho. Khuluma nodokotela wakho ngezimpawu zeshukela ephezulu yegazi nokuthi yini okufanele uyenze uma uhlangabezana nalezi zimpawu.
• Umjovo wePhenytoin ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo noma lezo ezisohlwini lwe-SPECIAL PRECAUTIONS section, shayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

Ungahle ubhekane nengcindezi yegazi ephansi noma esongela impilo noma isigqi senhliziyo esingajwayelekile ngenkathi uthola umjovo we-phenytoin noma ngemuva kwalokho. Tshela udokotela wakho uma ngabe uke waba nezigqi zenhliziyo ezingajwayelekile noma i-heart block (isimo lapho izimpawu zikagesi zingadluliswa ngokujwayelekile kusuka kumagumbi aphezulu enhliziyo kuya emakamelweni aphansi). Udokotela wakho angahle angafuni ukuthi uthole umjovo we-phenytoin. Futhi, tshela udokotela wakho uma ngabe uke waba nokuhluleka kwenhliziyo noma umfutho ophansi wegazi. Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo, tshela udokotela wakho ngokushesha: isiyezi, ukukhathala, ukushaya kwenhliziyo okungajwayelekile, noma ubuhlungu besifuba.

Uzothola umthamo ngamunye womjovo we-phenytoin esikhungweni sezokwelapha, futhi udokotela noma umhlengikazi uzokuqapha ngokucophelela ngenkathi uthola umuthi nangemuva kwalokho.

Umjovo we-Phenytoin usetshenziselwa ukwelapha ukuqubuka kwe-tonic-clonic okuyisisekelo (okwaziwa ngaphambili ngokuthi ukuqubuka okukhulu komzimba; ukuquleka okubandakanya umzimba wonke) nokwelapha nokuvimbela ukuquleka okungase kuqale ngesikhathi noma ngemuva kokuhlinzwa kuya ebuchosheni noma ohlelweni lwezinzwa. Umjovo we-Phenytoin ungasetshenziselwa ukulawula izinhlobo ezithile zokubanjwa kwabantu abangakwazi ukuthatha i-phenytoin yomlomo. I-Phenytoin isekilasini lemithi ebizwa ngama-anticonvulsants. Isebenza ngokunciphisa umsebenzi kagesi ongajwayelekile ebuchosheni.

Umjovo wePhenytoin uza njengesisombululo (uketshezi) sokujova kancane ngaphakathi (emthanjeni) ngudokotela noma umhlengikazi esikhungweni sezokwelapha. Kuvamise ukujova kanye njalo emahoreni ayisithupha noma ayisishiyagalombili.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Umjovo wePhenytoin nawo usetshenziselwa ukulawula ukushaya kwenhliziyo okungajwayelekile. Khuluma nodokotela wakho ngezingozi zokusebenzisa lo muthi ngesimo sakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola umjovo we-phenytoin,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-phenytoin, eminye imithi ye-hydantoin efana ne-ethotoin (Peganone) noma i-fosphenytoin (i-Cerebyx), noma yimiphi eminye imithi, noma iziphi izithako zomjovo we-phenytoin. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho uma uthatha i-delavirdine (Rescriptor). Udokotela wakho cishe ngeke afune ukuthi uthole umjovo we-phenytoin uma uthatha lo muthi.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: i-albendazole (i-Albenza); i-amiodarone (i-Nexterone, i-Pacerone); ama-anticoagulants (’ama-thinner egazi’) njenge-warfarin (i-Coumadin, i-Jantoven); imishanguzo yokulwa nobuthi efana ne-fluconazole (i-Diflucan), i-ketoconazole (i-Nizoral), i-itraconazole (i-Onmel, i-Sporanox, i-Tolsura), i-miconazole (i-Oravig), i-posaconazole (i-Noxafil), ne-voriconazole (i-Vfend); imishanguzo ethile efana ne-efavirenz (Sustiva, e-Atripla), indinavir (Crixivan), lopinavir (e-Kaletra), i-nelfinavir (i-Viracept), i-ritonavir (i-Norvir, e-Kaletra), ne-saquinavir (i-Invirase); i-bleomycin; i-capecitabine (Xeloda); i-carboplatin; i-chloramphenicol; i-chlordiazepoxide (iLibrium, eLibrax); imithi ye-cholesterol efana ne-atorvastatin (Lipitor, eCaduet), i-fluvastatin (Lescol), ne-simvastatin (iZocor, eVytorin); i-cisplatin; i-clozapine (iFazaclo, iVersacloz); i-cyclosporine (Gengraf, Neoral, Sandimmune); diazepam (Valium); diazoxide (Proglycem); i-digoxin (i-Lanoxin); i-disopyramide (iNorpace); i-disulfiram (i-Antabuse); i-doxorubicin (Doxil); doxycycline (Acticlate, Doryx, Monodox, Oracea, Vibramycin); i-fluorouracil; i-fluoxetine (i-Prozac, i-Sarafem, ku-Symbyax, abanye); i-fluvoxamine (i-Luvox); i-folic acid; i-fosamprenavir (Lexiva); i-furosemide (i-Lasix); H₂ abaphikisana nabo njenge-cimetidine (Tagamet), i-famotidine (i-Pepcid), i-nizatidine (i-Axid), ne-ranitidine (i-Zantac); izindlela zokuvimbela inzalo zamahomoni (amaphilisi okulawula ukubeletha, amabala, izindandatho, noma imijovo); ukwelashwa kwe-hormone replacement (HRT); i-irinotecan (iCamptosar); i-isoniazid (iLaniazid, eRifamate, eRifater); imithi yokugula ngengqondo kanye nesicanucanu; eminye imithi yokwelashwa okufana ne-carbamazepine (Carbatrol, Equetro, Tegretol, abanye), ethosuximide (Zarontin), felbamate (Felbatol), lamotrigine (Lamictal), methsuximide (Celontin), oxcarbazepine (Trilepta, Oxtellar XR), phenobate XR), phenobate ), kanye ne-valproic acid (Depakene); i-methadone (i-Dolophine, i-Methadose); i-methotrexate (i-Otrexup, i-Rasuvo, i-Trexall, i-Xatmep); i-methylphenidate (Daytrana, Concerta, Metadate, Ritalin); i-mexiletine; i-nifedipine (i-Adalat, i-Procardia), i-nimodipine (i-Nymalize), i-nisoldipine (i-Sular); omeprazole (Prilosec); i-steroids yomlomo efana ne-dexamethasone, i-methylprednisolone (i-Medrol), i-prednisolone, ne-prednisone (i-Rayos); i-paclitaxel (i-Abraxane, i-Taxol); i-paroxetine (Paxil, Pexeva); i-praziquantel (i-Biltricide); i-quetiapine (iSeroquel); i-quinidine (ku-Nuedexta); qamba kabusha; i-rifampin (iRifadin, iRimactane, eRifamate, eRifater); ubuhlungu be-salicylate buqeda njenge-aspirin, i-choline magnesium trisalicylate, i-choline salicylate, i-diflunisal, i-magnesium salicylate (i-Doan's, abanye), ne-salsalate; i-sertraline (iZoloft); i-sulfa antibiotic; i-teniposide; i-theophylline (i-Elixophyllin, i-Theo-24, i-Theochron); i-ticlopidine; tolbutamide; i-trazodone; i-verapamil (Calan, Verelan, eTarka); i-vigabatrin (iSabril); novithamini D. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• utshele udokotela wakho ukuthi uthatha miphi imikhiqizo yamakhambi, ikakhulukazi iSt John's wort.
• utshele udokotela wakho ukuthi wake waba nenkinga yesibindi ngenkathi uthatha i-phenytoin. Udokotela wakho cishe ngeke afune ukuthi uthole umjovo we-phenytoin.
• utshele udokotela wakho uma uphuza noma wake waphuza utshwala obuningi. Tshela udokotela wakho uma ngabe uhlolwe elabhorethri okubike ukuthi unesici esizuzwe njengefa esenza kube namathuba amaningi okuthi ube nokuphendula okunamandla kwesikhumba ku-phenytoin. Futhi, tshela udokotela wakho uma uke waba nesifo sikashukela noma i-porphyria (isimo lapho izinto ezithile zemvelo zakha khona emzimbeni futhi zingadala ubuhlungu besisu, izinguquko ekucabangeni noma ekuziphatheni, noma ezinye izimpawu), amazinga aphansi e-albin ku igazi, noma isifo sezinso noma sesibindi.
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Akufanele ukhulelwe ngenkathi uthola i-phenytoin. Khuluma nodokotela wakho ngezindlela ezisebenzayo zokulawula ukubeletha ongazisebenzisa ngesikhathi sokwelashwa kwakho. Uma ukhulelwa ngenkathi uthola i-phenytoin, shayela udokotela wakho. I-Phenytoin ingalimaza umbungu.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi uthola i-phenytoin.
• Kufanele wazi ukuthi lo muthi ungadala isiyezi, ukozela, nezinkinga ngokuxhumana. Ungashayeli imoto noma usebenzise imishini uze wazi ukuthi lo muthi ukuthinta kanjani.
• khuluma nodokotela wakho ngokusetshenziswa okuphephile kotshwala ngenkathi uthatha lo muthi.
• khuluma nodokotela wakho ngendlela engcono yokunakekela amazinyo akho, izinsini, nomlomo ngenkathi welashwa nge-phenytoin. Kubaluleke kakhulu ukuthi unakekele umlomo wakho kahle ukwehlisa ubungozi bokulimazeka kwezinsini okubangelwa yi-phenytoin.

I-Phenytoin ingadala ukwanda kushukela wegazi lakho. Khuluma nodokotela wakho ngezimpawu zeshukela ephezulu yegazi nokuthi yini okufanele uyenze uma uhlangabezana nalezi zimpawu.

Umjovo wePhenytoin ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ubunzima bokulala noma ukulala
• ukunyakaza kwamehlo okungalawuleki
• ukunyakaza komzimba okungajwayelekile
• ukulahleka kokuxhumanisa
• ukudideka
• inkulumo engahambi kahle
• ikhanda
• ushintsho kumqondo wakho wokunambitha
• ukuqunjelwa
• ukukhula kwezinwele okungafuneki
• ukuqina kwezici zobuso
• ukukhuliswa kwezindebe
• ukukhula kwezinsini
• ubuhlungu noma ukusonga kwenduku

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo noma lezo ezisohlwini lwe-SPECIAL PRECAUTIONS section, shayela udokotela wakho ngokushesha:

• ukuvuvukala, ukushintsha kombala, noma ubuhlungu endaweni yomjovo
• ukuqubuka
• isifuba
• ukulunywa
• ukuvuvukala kwamehlo, ubuso, umphimbo, ulimi, izingalo, izandla, amaqakala noma imilenze engezansi
• ukuphefumula kanzima noma ukugwinya
• ukushaqeka
• izindlala ezivuvukele
• isicanucanu
• ukuhlanza
• ukuphuzi kwesikhumba noma kwamehlo
• ubuhlungu engxenyeni engenhla kwesokudla yesisu
• ukukhathala ngokweqile
• ukulimaza noma ukopha okungavamile
• amabala amancane abomvu noma ansomi esikhunjeni
• ukulahlekelwa isifiso sokudla
• izimpawu ezinjengomkhuhlane
• umkhuhlane, umphimbo obuhlungu, ukuqubuka, izilonda zomlomo, noma ukulimazeka okulula, noma ukuvuvukala kobuso

Umjovo wePhenytoin ungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Ukuthatha i-phenytoin kungakhuphula ubungozi bokuthi uzoba nezinkinga ngama-lymph node wakho kubandakanya isifo sikaHodgkin (umdlavuza oqala ohlelweni lwe-lymph). Khuluma nodokotela wakho ngezingozi zokusebenzisa lo muthi ukwelapha isimo sakho.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• ukunyakaza kwamehlo okungalawuleki
• ukulahleka kokuxhumanisa
• inkulumo ehamba kancane noma engacacile
• ukukhathala
• ukungaboni kahle
• ukuzamazama okungalawuleki kwengxenye yomzimba
• isicanucanu
• ukuhlanza

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho anga-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yakho kumjovo we-phenytoin.

Ngaphambi kokwenza noma yiluphi uvivinyo lwelabhoratri, tshela udokotela wakho kanye nabasebenzi baselebhu ukuthi uthola umjovo we-phenytoin.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• UDilantin^®¶

^¶ Lo mkhiqizo onophawu alusekho emakethe. Ezinye izindlela ezijwayelekile zingatholakala.