I-Bempedoic Acid

-Delile

• Ngaphambi kokuthatha i-bempedoic acid,
• I-Bempedoic acid ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, yeka ukuthatha i-bempedoic acid bese ushayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

I-Bempedoic acid isetshenziswa kanye nokushintsha kwendlela yokuphila (ukudla, ukwehlisa isisindo, ukuvivinya umzimba) kanye nemithi ethile yokwehlisa i-cholesterol (HMG-CoA reductase inhibitors [statins]) ukwehlisa ukwehla kwe-low-density lipoprotein (LDL) cholesterol ('cholesterol embi') egazini labantu abadala abane-heterozygous hypercholesterolemia yomndeni (HeFH; isimo esizuzwe njengefa lapho i-cholesterol ingeke isuswe emzimbeni ngokujwayelekile) noma isifo senhliziyo. I-Bempedoic acid isekilasini lemithi ebizwa nge-adenosine triphosphate-citrate lyase (ACL) inhibitors. Isebenza ngokuvimba ukukhiqizwa kwe-cholesterol esibindini.

I-Bempedoic acid iza njengethebhulethi ezothathwa ngomlomo. Imvamisa kuthathwa kanye ngosuku noma ngaphandle kokudla. Thatha i-bempedoic acid ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-bempedoic acid njengoba nje kuqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-bempedoic acid,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-bempedoic acid, noma imiphi eminye imithi, noma iziphi izithako ezibhebheni ze-bempedoic acid. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: ama-antibiotic e-fluoroquinolone afaka i-ciprofloxacin (Cipro), i-gatifloxacin (i-Zymar, i-Zymaxid), i-levofloxacin (i-Levaquin), noma i-ofloxacin; i-pravastatin (Pravachol); simvastatin (Flolipid, eVytorin); noma i-oral or injectable steroids efana ne-dexamethasone, methylprednisolone (Medrol), noma i-prednisone (i-Rayos). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• Tshela udokotela wakho uma ngabe uke waba ne-gout, i-tendon (isicubu esinezicubu esixhuma ithambo nemisipha), noma isifo sezinso noma sesibindi.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha i-bempedoic acid, shayela udokotela wakho.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Bempedoic acid ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ukuphazamiseka kwemisipha
• ukuhlungu obusemhlane
• ubuhlungu ezandleni noma ezinyaweni

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, yeka ukuthatha i-bempedoic acid bese ushayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ubuhlungu obukhulu, ububomvu, ukufudumala, isisa, noma ukuvuvukala kwamalunga, ikakhulukazi endaweni enkulu yezwane
• ukuzwa noma ukuzwa i-snap noma i-pop endaweni yethenda; ukulimaza ngemuva kokulimala endaweni yethenda; noma ukungakwazi ukuhambisa noma ukuthwala isisindo endaweni ethintekile yethenda

I-Bempedoic acid ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese). Ungayikhiphi i-desiccant (iphakethe elincane elifakwe namathebulethi ukumunca umswakama) ebhodleleni lakho.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ku-bempedoic acid.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Nexletol^®

• I-Nexlizet^® (equkethe iBempedoic Acid, Ezetimibe)