ICapmatinib

-Delile

• Ngaphambi kokuthatha i-capmatinib,
• ICapmatinib ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

ICapmatinib isetshenziselwa ukwelapha uhlobo oluthile lomdlavuza wamaphaphu weseli (non-small) wamaphaphu (NSCLC) osabalalele kwezinye izingxenye zomzimba. ICapmatinib isekilasini lemithi ebizwa nge-kinase inhibitors. Isebenza ngokuvimba isenzo sephrotheni engavamile ekhombisa ukuthi amangqamuzana omdlavuza ayanda. Lokhu kusiza ukunciphisa noma ukumisa ukusabalala kwamangqamuzana omdlavuza.

ICapmatinib iza njengethebhulethi ezothathwa ngomlomo. Imvamisa kuthathwa kabili ngosuku noma ngaphandle kokudla. Thatha i-capmatinib ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-capmatinib njengoba iqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Gwinya wonke amaphilisi; ungawahlukanisi, ungawahlafune noma uwagxoze.

Uma uhlanza ngemuva kokuthatha i-capmatinib, ungathathi omunye umthamo. Qhubeka nesimiso sakho sokulinganisa okuvamile.

Udokotela wakho angadinga ukumisa ukwelashwa kwakho okwesikhashana noma unomphela noma anciphise umthamo wakho we-capmatinib ngesikhathi sokwelashwa kwakho. Lokhu kuncike ekutheni umuthi usebenza kanjani kuwe kanye nemiphumela emibi oyitholayo. Qiniseka ukuthi utshela udokotela wakho ukuthi uzizwa kanjani ngesikhathi sokwelashwa kwakho nge-capmatinib.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-capmatinib,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-capmatinib, noma imuphi omunye umuthi, noma iziphi izithako kumaphilisi e-capmatinib. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: i-amitriptyline, i-carbamazepine (iCarbatrol, i-Epitol, iTegretol, nezinye); i-clarithromycin (ku-Biaxin); i-clozapine (iVersacloz); ama-corticosteroids; imishanguzo ethile yegciwane lesandulela-ngculazi (i-HIV) noma i-immunodeficiency syndrome (i-AIDS) efana ne-efavirenz (Sustiva, e-Atripla), indinavir (Crixivan), nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norvir, e Kaletra), kanye i-saquinavir (i-Invirase); itraconazole (Onmel, Sporanox, Tolsura); ketoconazole; nefazodone; oxcarbazepine (Trileptal); i-phenobarbital; i-phenytoin (iDilantin, Phenytek); i-pioglitazone (Actos, eDuetact, e-Oseni); i-rifabutin (i-Mycobutin); i-rifampin (iRifadin, iRimactane, eRifater); i-rosuvastatin (iCrestor, i-Ezallor); i-verapamil (Verelan, eTarka); noma i-warfarin (Coumadin, Jantoven). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo eminingi ingaxhumana ne-capmatinib, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu.
• utshele udokotela wakho ukuthi uthatha miphi imikhiqizo yamakhambi, ikakhulukazi iSt John's wort.
• Tshela udokotela wakho uma uke waba nesifo samaphaphu noma izinkinga zokuphefumula ngaphandle komdlavuza wamaphaphu, noma isifo sesibindi.
• utshele udokotela wakho uma ukhulelwe, noma uhlele ukukhulelwa. Akufanele ukhulelwe ngenkathi uthatha i-capmatinib. Uzodinga ukuhlolwa kokukhulelwa ngaphambi kokuqala ukwelashwa, futhi kufanele usebenzise ukuvimbela ukukhulelwa ukuvimbela ukukhulelwa ngesikhathi sokwelashwa kwakho futhi okungenani isonto elilodwa ngemuva komthamo wakho wokugcina. Uma ungowesilisa onomlingani wesifazane ongakhulelwa, kufanele usebenzise ukuvimbela ukukhulelwa ukuvimbela ukukhulelwa ngenkathi welashwa futhi okungenani isonto elilodwa ngemuva komthamo wakho wokugcina. ICapmatinib ingalimaza ingane yakho engakazalwa. Uma wena noma umlingani wakho ukhulelwa ngesikhathi sokwelashwa kwakho nge-capmatinib, shayela udokotela wakho ngokushesha.
• tshela udokotela wakho uma uncelisa. Akufanele uncelise ngenkathi uthatha i-capmatinib futhi okungenani isonto elilodwa ngemuva komthamo wakho wokugcina.
• hlela ukugwema ukuvezwa yilanga ngokungadingekile noma isikhathi eside nokugqoka isigqoko, ezinye izingubo zokuzivikela, izibuko zelanga, kanye nelanga.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Yeqa umthamo ophuthelwe bese uqhubeka nesimiso sakho sokulinganisa esivamile. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

ICapmatinib ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ukuhlanza
• isicanucanu
• ukukhathala
• ukuqunjelwa
• ukuncipha komzimba
• ukuhlungu obusemhlane
• ukulahlekelwa isifiso sokudla
• ukukhathala
• ukuvuvukala ezandleni, ezinyaweni, emaqakaleni, noma emilenzeni engezansi

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukuphefumula, ukukhwehlela, umkhuhlane, noma ezinye izimpawu zokutheleleka
• ubuhlungu besifuba
• ubuhlungu engxenyeni engenhla yesisu; ukulimaza noma ukopha okungavamile; umchamo omnyama; ukuphuzi kwesikhumba namehlo; noma ukulahlekelwa isifiso sokudla

I-Capmatinib ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina lo muthi esitsheni uwafake ngaphakathi, uvalwe uvalwe, futhi lapho izingane zingafinyelele khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese). Ungayisusi i-desiccant (igobolondo elincane elifakwe namathebulethi ukumunca umswakama) ebhodleleni lakho. Lahla noma imaphi amaphilisi angasetshenziswanga emasontweni ayisithupha ngemuva kokuvula ibhodlela kuqala.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ku-capmatinib.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

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